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Search results 1 to 100 out of 347 for Cdh23

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0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Cadherin-23 (CDH23) is an adhesion protein that contains several calcium dependent extracellular (EC) domains. It is required for establishing and/or maintaining the proper organisation of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development []. CDH23 is part of the tip-links, oblique filaments that interconnect the stereocilia of the hair bundle []. CDH23 is associated with Usher syndrome type 1 (USH1D), isolated deafness (DFNB12) in humans, and deafness and circling behavior in waltzer mice [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Lagziel A
Year: 2005
Journal: Dev Biol
Title: Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development.
Volume: 280
Issue: 2
Pages: 295-306
Publication
First Author: Bolz H
Year: 2001
Journal: Nat Genet
Title: Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D.
Volume: 27
Issue: 1
Pages: 108-12
Publication
First Author: Caberlotto E
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.
Volume: 108
Issue: 14
Pages: 5825-30
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Sengupta S
Year: 2009
Journal: J Biol Chem
Title: EHD4 and CDH23 are interacting partners in cochlear hair cells.
Volume: 284
Issue: 30
Pages: 20121-9
Publication
First Author: Wilson SM
Year: 2001
Journal: Genomics
Title: Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice.
Volume: 74
Issue: 2
Pages: 228-33
Publication      
First Author: Harris BS
Year: 2005
Journal: MGI Direct Data Submission
Title: Waltzer 7 Jackson, a remutation of the Cdh23 gene
Publication
First Author: Liu S
Year: 2012
Journal: Gene
Title: A mutation in the cdh23 gene causes age-related hearing loss in Cdh23(nmf308/nmf308) mice.
Volume: 499
Issue: 2
Pages: 309-17
Publication
First Author: Manji SS
Year: 2011
Journal: Am J Pathol
Title: An ENU-induced mutation of Cdh23 causes congenital hearing loss, but no vestibular dysfunction, in mice.
Volume: 179
Issue: 2
Pages: 903-14
Publication
First Author: Kane KL
Year: 2012
Journal: Hear Res
Title: Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice.
Volume: 283
Issue: 1-2
Pages: 80-8
Publication  
First Author: Watson CJ
Year: 2013
Journal: Hear Res
Title: A new Atp2b2 deafwaddler allele, dfw(i5), interacts strongly with Cdh23 and other auditory modifiers.
Volume: 304
Pages: 41-8
Publication
First Author: Libby RT
Year: 2003
Journal: Exp Eye Res
Title: Cdh23 mutations in the mouse are associated with retinal dysfunction but not retinal degeneration.
Volume: 77
Issue: 6
Pages: 731-9
Publication      
First Author: Kane K
Year: 2008
Journal: MGI Direct Data Submission
Title: Jackson waltzer 11J, a new spontaneous mutation in the Cdh23 gene
Publication
First Author: Johnson KR
Year: 2010
Journal: Hear Res
Title: Separate and combined effects of Sod1 and Cdh23 mutations on age-related hearing loss and cochlear pathology in C57BL/6J mice.
Volume: 268
Issue: 1-2
Pages: 85-92
Publication
First Author: Rzadzinska AK
Year: 2009
Journal: Neuroscience
Title: Presence of interstereocilial links in waltzer mutants suggests Cdh23 is not essential for tip link formation.
Volume: 158
Issue: 2
Pages: 365-8
Publication
First Author: Holme RH
Year: 2004
Journal: J Assoc Res Otolaryngol
Title: Progressive hearing loss and increased susceptibility to noise-induced hearing loss in mice carrying a Cdh23 but not a Myo7a mutation.
Volume: 5
Issue: 1
Pages: 66-79
Publication  
First Author: Johnson KR
Year: 2017
Journal: Sci Rep
Title: Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains.
Volume: 7
Pages: 44450
Publication
First Author: Han F
Year: 2012
Journal: Pharmacogenomics J
Title: A new mouse mutant of the Cdh23 gene with early-onset hearing loss facilitates evaluation of otoprotection drugs.
Volume: 12
Issue: 1
Pages: 30-44
Publication
First Author: Johnson KR
Year: 2008
Journal: Genomics
Title: A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice.
Volume: 92
Issue: 4
Pages: 219-25
Protein
Organism: Mus musculus
Length: 3354  
Fragment?: false
Protein
Organism: Mus musculus
Length: 3321  
Fragment?: false
Protein
Organism: Mus musculus
Length: 283  
Fragment?: true
Protein
Organism: Mus musculus
Length: 3353  
Fragment?: false
Protein
Organism: Mus musculus
Length: 3352  
Fragment?: false
Protein
Organism: Mus musculus
Length: 3283  
Fragment?: false
Protein
Organism: Mus musculus
Length: 3267  
Fragment?: false
Protein
Organism: Mus musculus
Length: 347  
Fragment?: true
Protein
Organism: Mus musculus
Length: 3352  
Fragment?: false
Publication      
First Author: Prince L
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for hersey.
Publication
First Author: Noben-Trauth K
Year: 2003
Journal: Nat Genet
Title: Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss.
Volume: 35
Issue: 1
Pages: 21-3
Publication
First Author: Bork JM
Year: 2001
Journal: Am J Hum Genet
Title: Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23.
Volume: 68
Issue: 1
Pages: 26-37
Publication
First Author: Di Palma F
Year: 2001
Journal: Nat Genet
Title: Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D.
Volume: 27
Issue: 1
Pages: 103-7
Publication
First Author: Yonezawa S
Year: 2006
Journal: Hum Mutat
Title: Fates of Cdh23/CDH23 with mutations affecting the cytoplasmic region.
Volume: 27
Issue: 1
Pages: 88-97
Publication  
First Author: Mock BE
Year: 2016
Journal: Neurobiol Aging
Title: Differential effects of Cdh23(753A) on auditory and vestibular functional aging in C57BL/6J mice.
Volume: 43
Pages: 13-22
Publication
First Author: Mianné J
Year: 2016
Journal: Genome Med
Title: Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair.
Volume: 8
Issue: 1
Pages: 16
Publication
First Author: Miyasaka Y
Year: 2013
Journal: Exp Anim
Title: Compound heterozygosity of the functionally null Cdh23(v-ngt) and hypomorphic Cdh23(ahl) alleles leads to early-onset progressive hearing loss in mice.
Volume: 62
Issue: 4
Pages: 333-46
Publication  
First Author: Burghard AL
Year: 2019
Journal: Neurobiol Aging
Title: Mice heterozygous for the Cdh23/Ahl1 mutation show age-related deficits in auditory temporal processing.
Volume: 81
Pages: 47-57
Publication
First Author: Elledge HM
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members.
Volume: 107
Issue: 23
Pages: 10708-12
Publication
First Author: Zheng QY
Year: 2009
Journal: Neurobiol Aging
Title: A locus on distal chromosome 10 (ahl4) affecting age-related hearing loss in A/J mice.
Volume: 30
Issue: 10
Pages: 1693-705
Publication
First Author: Xu Z
Year: 2008
Journal: J Neurosci
Title: MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23.
Volume: 28
Issue: 44
Pages: 11269-76
Publication
First Author: Di Palma F
Year: 2001
Journal: Gene
Title: Genomic structure, alternative splice forms and normal and mutant alleles of cadherin 23 (Cdh23).
Volume: 281
Issue: 1-2
Pages: 31-41
Publication
First Author: Zheng QY
Year: 2005
Journal: Hum Mol Genet
Title: Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans.
Volume: 14
Issue: 1
Pages: 103-11
Publication
First Author: Johnson KR
Year: 2005
Journal: Genomics
Title: The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.
Volume: 85
Issue: 5
Pages: 582-90
Publication
First Author: Miyasaka Y
Year: 2016
Journal: Hum Mol Genet
Title: Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.
Volume: 25
Issue: 10
Pages: 2045-2059
Publication
First Author: Schwander M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells.
Volume: 106
Issue: 13
Pages: 5252-7
Publication
First Author: Kazmierczak P
Year: 2007
Journal: Nature
Title: Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.
Volume: 449
Issue: 7158
Pages: 87-91
Publication
First Author: Drayton M
Year: 2006
Journal: Hear Res
Title: Mapping quantitative trait loci for hearing loss in Black Swiss mice.
Volume: 212
Issue: 1-2
Pages: 128-39
Publication
First Author: Phillips KR
Year: 2006
Journal: J Neurosci
Title: Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice.
Volume: 26
Issue: 42
Pages: 10777-88
Publication
First Author: Holme RH
Year: 2002
Journal: Hear Res
Title: Stereocilia defects in waltzer (Cdh23), shaker1 (Myo7a) and double waltzer/shaker1 mutant mice.
Volume: 169
Issue: 1-2
Pages: 13-23
Publication
First Author: Alagramam KN
Year: 2011
Journal: PLoS One
Title: Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells.
Volume: 6
Issue: 4
Pages: e19183
Publication
First Author: Zheng L
Year: 2010
Journal: J Neurosci
Title: Targeting of the hair cell proteins cadherin 23, harmonin, myosin XVa, espin, and prestin in an epithelial cell model.
Volume: 30
Issue: 21
Pages: 7187-201
Publication  
First Author: Lagziel A
Year: 2009
Journal: Mol Vis
Title: Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D.
Volume: 15
Pages: 1843-57
Publication
First Author: Zheng QY
Year: 2012
Journal: Hum Mol Genet
Title: Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genes.
Volume: 21
Issue: 11
Pages: 2588-98
Publication
First Author: Johnson KR
Year: 2006
Journal: Brain Res
Title: Strain background effects and genetic modifiers of hearing in mice.
Volume: 1091
Issue: 1
Pages: 79-88
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lutz CM
Year: 1995
Journal: Mouse Genome
Title: Remutation at the waltzer locus
Volume: 93
Issue: 3
Pages: 862
Publication
First Author: Harding GW
Year: 2005
Journal: Hear Res
Title: The effect of an age-related hearing loss gene (Ahl) on noise-induced hearing loss and cochlear damage from low-frequency noise.
Volume: 204
Issue: 1-2
Pages: 90-100
Publication
First Author: Noben-Trauth K
Year: 2010
Journal: PLoS One
Title: Phenotype and genetics of progressive sensorineural hearing loss (Snhl1) in the LXS set of recombinant inbred strains of mice.
Volume: 5
Issue: 7
Pages: e11459
Publication  
First Author: Hu J
Year: 2016
Journal: Neuroscience
Title: Tauroursodeoxycholic acid prevents hearing loss and hair cell death in Cdh23(erl/erl) mice.
Volume: 316
Pages: 311-20
Publication  
First Author: Han F
Year: 2013
Journal: Neuroscience
Title: Otoprotective effects of erythropoietin on Cdh23erl/erl mice.
Volume: 237
Pages: 1-6
Publication
First Author: Hu J
Year: 2016
Journal: Cell Death Dis
Title: ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23erl/erl mutant mice.
Volume: 7
Issue: 11
Pages: e2485
Publication      
First Author: Dismang A
Year: 2013
Journal: MGI Direct Data Submission
Title: Direct Data Submission for dee dee mutation
Publication          
First Author: Keeler CE
Year: 1931
Publication
First Author: Deol MS
Year: 1956
Journal: J Embryol Exp Morphol
Title: A gene for uncomplicated deafness in the mouse.
Volume: 4
Issue: 2
Pages: 190-195
Publication  
First Author: Otani H
Year: 1995
Journal: Acta Otolaryngol Suppl
Title: Vestibulocochlear defects and effects of deuterium oxide in mutant bustling (BUS) mice.
Volume: 519
Pages: 286-93
Publication  
First Author: Hanai A
Year: 1995
Journal: Cong Anom
Title: BUS/ldr, a mutant mouse strain exhibiting abnormal behaviors: Behavioral similarities of BUS mice and chemically labyrinthectomized mice.
Volume: 35
Pages: 467-75
Publication
First Author: Yonezawa S
Year: 1999
Journal: Hear Res
Title: Chromosomal localization of a gene responsible for vestibulocochlear defects of BUS/Idr mice: identification as an allele of waltzer.
Volume: 134
Issue: 1-2
Pages: 116-22
Publication
First Author: Moriyama K
Year: 1997
Journal: Acta Otolaryngol
Title: Degenerative hairlets on the vestibular sensory cells in mutant bustling (BUS/Idr) mice.
Volume: 117
Issue: 1
Pages: 20-4
Publication      
First Author: Zheng Y
Year: 1998
Journal: MGI Direct Data Submission
Title: The Jackson Laboratory Mouse Mutant Resource Mutation Reports
Publication      
First Author: Pelletier KM
Year: 1998
Journal: MGI Direct Data Submission
Title: The Jackson Laboratory Mouse Mutant Resource Mutation Reports
Publication
First Author: Vu AA
Year: 2013
Journal: PLoS One
Title: Integrity and regeneration of mechanotransduction machinery regulate aminoglycoside entry and sensory cell death.
Volume: 8
Issue: 1
Pages: e54794
Publication
First Author: Wada T
Year: 2001
Journal: Biochem Biophys Res Commun
Title: A point mutation in a cadherin gene, Cdh23, causes deafness in a novel mutant, Waltzer mouse niigata.
Volume: 283
Issue: 1
Pages: 113-7
Publication
First Author: Keithley EM
Year: 2004
Journal: Hear Res
Title: Age-related hearing loss and the ahl locus in mice.
Volume: 188
Issue: 1-2
Pages: 21-8
Publication
First Author: Davis RR
Year: 2001
Journal: Hear Res
Title: Genetic basis for susceptibility to noise-induced hearing loss in mice.
Volume: 155
Issue: 1-2
Pages: 82-90
Publication
First Author: Mathews CE
Year: 1999
Journal: Diabetes
Title: Resistance of ALR/Lt islets to free radical-mediated diabetogenic stress is inherited as a dominant trait.
Volume: 48
Issue: 11
Pages: 2189-96
Publication
First Author: Vázquez AE
Year: 2004
Journal: Hear Res
Title: Evaluating cochlear function and the effects of noise exposure in the B6.CAST+Ahl mouse with distortion product otoacoustic emissions.
Volume: 194
Issue: 1-2
Pages: 87-96
Publication
First Author: Johnson KR
Year: 2001
Journal: Nat Genet
Title: A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice.
Volume: 27
Issue: 2
Pages: 191-4