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Search results 1 to 100 out of 134 for Cdk12

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
51755 | CDK12
Type: gene
Organism: human
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Gene
100038049 | cdk12
Type: gene
Organism: frog, western clawed
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Gene
192350 | Cdk12
Type: gene
Organism: rat
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Gene
454630 | CDK12
Type: gene
Organism: chimpanzee
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Gene
491027 | CDK12
Type: gene
Organism: dog, domestic
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Gene
511513 | CDK12
Type: gene
Organism: cattle
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Gene
428306 | CDK12
Type: gene
Organism: chicken
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Gene
100149834 | cdk12
Type: gene
Organism: zebrafish
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Gene
696733 | CDK12
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1098802 | Cdk12
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
39368479 | J:378395
First Author: Tien JC
Year: 2024
Journal: Cell Rep Med
Title: CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13.
Volume: 5
Issue: 10
Pages: 101758
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Publication
27073218 | J:241332
First Author: Chen HR
Year: 2017
Journal: Cereb Cortex
Title: Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex.
Volume: 27
Issue: 3
Pages: 2289-2302
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Publication
24999027 | J:217121
 
First Author: Chen HR
Year: 2014
Journal: Exp Neurol
Title: Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.
Volume: 261
Pages: 10-21
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Publication
26658019 | J:242195
First Author: Juan HC
Year: 2016
Journal: Cell Death Differ
Title: Cdk12 is essential for embryonic development and the maintenance of genomic stability.
Volume: 23
Issue: 6
Pages: 1038-48
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Publication
40504161 | J:368533
First Author: Tien JC
Year: 2025
Journal: Proc Natl Acad Sci U S A
Title: Defining CDK12 as a tumor suppressor and therapeutic target in mouse models of tubo-ovarian high-grade serous carcinoma.
Volume: 122
Issue: 24
Pages: e2426909122
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Publication
38481813 | J:360916
First Author: Zhang YL
Year: 2024
Journal: Int J Biol Sci
Title: Tubule-specific cyclin-dependent kinase 12 knockdown potentiates kidney injury through transcriptional elongation defects.
Volume: 20
Issue: 5
Pages: 1669-1687
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Publication
22547058 | J:192997
First Author: Dai Q
Year: 2012
Journal: J Biol Chem
Title: Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells.
Volume: 287
Issue: 30
Pages: 25344-52
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Protein Coding Gene
MGP_CAROLIEiJ_G0017077 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200050418 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195051807 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220049711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180046950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175042661 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1098802 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215052935 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005048245 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210052006 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185045760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205037423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230050679 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000035295 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190051392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225050413 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010050268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005043347 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018206 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010043224 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5632297
Assay Type: Western blot
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608915
Stage: TS15
Assay Id: MGI:5632313
Age: embryonic day 9.5
Image: 1
Specimen Label: E9.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5632297
Assay Type: Western blot
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:5632313
Age: embryonic day 13.5
Image: 1
Specimen Label: E13.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5632297
Assay Type: Western blot
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:5632313
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5632297
Assay Type: Western blot
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:5632313
Age: embryonic day 16.5
Image: 1
Specimen Label: E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5632297
Assay Type: Western blot
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:5632313
Age: embryonic day 17.5
Image: 1
Specimen Label: E17.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5632297
Assay Type: Western blot
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:5632313
Age: embryonic day 18.5
Image: 1
Specimen Label: E18.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5632297
Assay Type: Western blot
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5632313
Age: postnatal day 0
Image: 1
Specimen Label: P0
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6287131
Assay Type: RT-PCR
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6287208
Age: embryonic day 14.5
Image: 1
Specimen Label: fx/fx
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6287131
Assay Type: RT-PCR
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6287208
Age: embryonic day 14.5
Image: 1
Specimen Label: fx/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:942037
Assay Type: RNA in situ
Annotation Date: 2024-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7623556
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1675215
Pattern: Ubiquitous
Stage: TS15
Assay Id: MGI:5632302
Age: embryonic day 9.5
Image: 1Ad
Note: Stronger expression in tail bud mesoderm.
Specimen Label: 1Ad
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160373
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:6287215
Age: embryonic day 2.0
Image: 1Dh/r
Specimen Label: 1Dh/r
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6287215
Age: embryonic day 3.5
Image: 1Dj/t
Specimen Label: 1Dj/t
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614013
Pattern: Ubiquitous
Stage: TS13
Assay Id: MGI:5632302
Age: embryonic day 8.5
Image: 1Ac
Note: Stronger expression.
Specimen Label: 1Ac
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Ubiquitous
Stage: TS15
Assay Id: MGI:5632302
Age: embryonic day 9.5
Image: 1Ad
Note: Stronger expression.
Specimen Label: 1Ad
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5632315
Age: embryonic day 14.5
Image: S2 b/b'
Specimen Label: S2 b/b'
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610513
Stage: TS13
Assay Id: MGI:5632302
Age: embryonic day 8.5
Image: 1Ac
Specimen Label: 1Ac
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:5632302
Age: embryonic day 9.5
Image: 1Ad
Specimen Label: 1Ad
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160399
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:5632302
Age: embryonic day 6.5
Image: 1Aa
Specimen Label: 1Aa
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Ubiquitous
Stage: TS11
Assay Id: MGI:5632302
Age: embryonic day 7.5
Image: 1Ab
Note: Expressed in all cells.
Specimen Label: 1Ab
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:5632302
Age: embryonic day 8.5
Image: 1Ac
Note: Expressed in all cells, except the heart.
Specimen Label: 1Ac
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:5632302
Age: embryonic day 9.5
Image: 1Ad
Note: Expressed in all cells, except the heart.
Specimen Label: 1Ad
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Ubiquitous
Stage: TS13
Assay Id: MGI:5632302
Age: embryonic day 8.5
Image: 1Ac
Note: Stronger expression.
Specimen Label: 1Ac
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664015
Pattern: Ubiquitous
Stage: TS15
Assay Id: MGI:5632302
Age: embryonic day 9.5
Image: 1Ad
Note: Stronger expression.
Specimen Label: 1Ad
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607211
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5632302
Age: embryonic day 7.5
Image: 1Ab
Note: Stronger expression.
Specimen Label: 1Ab
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6287215
Age: embryonic day 3.5
Image: 1F
Note: Authors report greater expression in nucleus than at morula and earlier stages.
Specimen Label: 1F
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618913
Pattern: Ubiquitous
Stage: TS13
Assay Id: MGI:5632302
Age: embryonic day 8.5
Image: 1Ac
Note: Stronger expression in tail bud mesoderm.
Specimen Label: 1Ac
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6287215
Age: embryonic day 3.0
Image: 1Di/s
Specimen Label: 1Di/s
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6287215
Age: embryonic day 3.0
Image: 1E
Note: Authors state that expression is evenly distributed across cytoplasm and nucleus from two-cell to morula stage.
Specimen Label: 1E
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:942037
Assay Type: RNA in situ
Annotation Date: 2024-04-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7623556
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5632300
Assay Type: RNA in situ
Annotation Date: 2015-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160469
Pattern: Not Specified
Stage: TS09
Assay Id: MGI:5632302
Age: embryonic day 6.5
Image: 1Aa
Specimen Label: 1Aa
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6287215
Age: embryonic day 3.5
Image: 1Dj/t
Specimen Label: 1Dj/t
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3102528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6287215
Age: postnatal adult
Image: 1Df/p
Specimen Label: 1Df/p
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5632297
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Not Specified
Stage: TS02
Assay Id: MGI:6287215
Age: embryonic day 1.0
Image: 1Dg/q
Specimen Label: 1Dg/q
Detected: true
Specimen Num: 2
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Publication
41261531 | J:387591
First Author: Yin Q
Year: 2026
Journal: HGG Adv
Title: Genetic landscape of morphine response in BXD recombinant inbred mice.
Volume: 7
Issue: 1
Pages: 100535
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Publication
11711534 | J:73962
First Author: Seykora JT
Year: 2002
Journal: J Biol Chem
Title: 'Srcasm: a novel Src activating and signaling molecule.
Volume: 277
Issue: 4
Pages: 2812-22
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Publication
- | J:165963
     
First Author: Centre for Modeling Human Disease
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto
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Publication
- | J:200814
     
First Author: Toronto Centre for Phenogenomics
Year: 2013
Journal: MGI Direct Data Submission
Title: Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051).
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Publication
15741177 | J:126097
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
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First Author: Stryke D
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Journal: Front Mol Neurosci
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First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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First Author: GO Central curators, GOA curators, Rhea curators
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First Author: Velocigene
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First Author: International Mouse Strain Resource
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First Author: Helmholtz Zentrum Muenchen GmbH
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Journal: MGI Direct Data Submission
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First Author: The Gene Ontology Consortium
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Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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First Author: Mouse Genome Informatics Scientific Curators
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Journal: Nature
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First Author: MGD Nomenclature Committee
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Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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