|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 1031 for Cdk2

<< First    < Previous  |  Next >    Last >>
0.045s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: hamster, golden
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Berthet C
Year: 2003
Journal: Curr Biol
Title: Cdk2 knockout mice are viable.
Volume: 13
Issue: 20
Pages: 1775-85
Publication
First Author: Hakem A
Year: 1999
Journal: J Exp Med
Title: The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis.
Volume: 189
Issue: 6
Pages: 957-68
Publication
First Author: Mateo F
Year: 2009
Journal: Nucleic Acids Res
Title: The transcriptional co-activator PCAF regulates cdk2 activity.
Volume: 37
Issue: 21
Pages: 7072-84
Publication
First Author: Arora M
Year: 2023
Journal: Cell
Title: Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity.
Volume: 186
Issue: 12
Pages: 2628-2643.e21
Publication
First Author: Macias E
Year: 2007
Journal: Cancer Res
Title: Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.
Volume: 67
Issue: 20
Pages: 9713-20
Publication
First Author: Palmer N
Year: 2020
Journal: PLoS Biol
Title: A novel function for CDK2 activity at meiotic crossover sites.
Volume: 18
Issue: 10
Pages: e3000903
Publication
First Author: Liu H
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Functional interaction of Puralpha with the Cdk2 moiety of cyclin A/Cdk2.
Volume: 328
Issue: 4
Pages: 851-7
Publication
First Author: Palmer N
Year: 2019
Journal: J Cell Biol
Title: CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I.
Volume: 218
Issue: 9
Pages: 2896-2918
Publication
First Author: Campaner S
Year: 2010
Journal: Nat Cell Biol
Title: Cdk2 suppresses cellular senescence induced by the c-myc oncogene.
Volume: 12
Issue: 1
Pages: 54-9; sup pp 1-14
Publication
First Author: Teitz T
Year: 2018
Journal: J Exp Med
Title: CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.
Volume: 215
Issue: 4
Pages: 1187-1203
Publication
First Author: Chauhan S
Year: 2016
Journal: Biochem J
Title: Cdk2 catalytic activity is essential for meiotic cell division in vivo.
Volume: 473
Issue: 18
Pages: 2783-98
Publication  
First Author: Singh P
Year: 2019
Journal: Development
Title: CDK2 kinase activity is a regulator of male germ cell fate.
Volume: 146
Issue: 21
Publication
First Author: Satyanarayana A
Year: 2008
Journal: Development
Title: Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2.
Volume: 135
Issue: 20
Pages: 3389-400
Publication
First Author: Viera A
Year: 2009
Journal: J Cell Sci
Title: CDK2 is required for proper homologous pairing, recombination and sex-body formation during male mouse meiosis.
Volume: 122
Issue: Pt 12
Pages: 2149-59
Publication
First Author: Granés F
Year: 2004
Journal: Eur J Immunol
Title: Cdk2 activation acts upstream of the mitochondrion during glucocorticoid induced thymocyte apoptosis.
Volume: 34
Issue: 10
Pages: 2781-90
Publication
First Author: Gopinathan L
Year: 2014
Journal: Cancer Res
Title: Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis.
Volume: 74
Issue: 14
Pages: 3870-9
Publication
First Author: Palmer N
Year: 2023
Journal: PLoS One
Title: Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity.
Volume: 18
Issue: 3
Pages: e0283590
Publication
First Author: Kwon TK
Year: 1998
Journal: Exp Cell Res
Title: The differential catalytic activity of alternatively spliced cdk2 alpha and cdk2 beta in the G1/S transition and early S phase.
Volume: 238
Issue: 1
Pages: 128-35
Publication
First Author: Liu W
Year: 2014
Journal: Dev Biol
Title: Phosphorylation of CDK2 at threonine 160 regulates meiotic pachytene and diplotene progression in mice.
Volume: 392
Issue: 1
Pages: 108-16
Publication  
First Author: Yoshida A
Year: 2013
Journal: Sci Rep
Title: CSN5 specifically interacts with CDK2 and controls senescence in a cytoplasmic cyclin E-mediated manner.
Volume: 3
Pages: 1054
Publication
First Author: Wang L
Year: 2014
Journal: Biol Reprod
Title: Phosphorylation of CDK2 on threonine 160 influences silencing of sex chromosome during male meiosis.
Volume: 90
Issue: 6
Pages: 138
Publication
First Author: Tsai LH
Year: 1991
Journal: Nature
Title: Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase.
Volume: 353
Issue: 6340
Pages: 174-7
Publication
First Author: Macias E
Year: 2008
Journal: Am J Pathol
Title: CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development.
Volume: 173
Issue: 2
Pages: 526-35
Publication  
First Author: Mikolcevic P
Year: 2016
Journal: Nat Commun
Title: Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope.
Volume: 7
Pages: 11084
Publication
First Author: Dobashi Y
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Cell cycle control with minimal participation of Cdk2 in a murine fibrosarcoma clone cultured in protein-free medium.
Volume: 232
Issue: 3
Pages: 622-5
Publication
First Author: Viera A
Year: 2015
Journal: J Cell Sci
Title: CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase.
Volume: 128
Issue: 1
Pages: 88-99
Publication
First Author: Jahn SC
Year: 2013
Journal: J Cell Sci
Title: Constitutive Cdk2 activity promotes aneuploidy while altering the spindle assembly and tetraploidy checkpoints.
Volume: 126
Issue: Pt 5
Pages: 1207-17
Publication
First Author: Sdao SM
Year: 2021
Journal: Cell Rep
Title: CDK2 limits the highly energetic secretory program of mature β cells by restricting PEP cycle-dependent KATP channel closure.
Volume: 34
Issue: 4
Pages: 108690
Publication
First Author: Martín A
Year: 2005
Journal: Cancer Cell
Title: Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).
Volume: 7
Issue: 6
Pages: 591-8
Publication
First Author: Akli S
Year: 2011
Journal: Cancer Res
Title: Cdk2 is required for breast cancer mediated by the low-molecular-weight isoform of cyclin E.
Volume: 71
Issue: 9
Pages: 3377-86
Publication
First Author: Maddika S
Year: 2008
Journal: J Cell Sci
Title: Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis.
Volume: 121
Issue: Pt 7
Pages: 979-88
Publication
First Author: Berthet C
Year: 2006
Journal: Dev Cell
Title: Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation.
Volume: 10
Issue: 5
Pages: 563-73
Publication
First Author: Lim S
Year: 2012
Journal: Stem Cells
Title: Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells.
Volume: 30
Issue: 7
Pages: 1509-20
Publication
First Author: Padmakumar VC
Year: 2009
Journal: Mol Cell Biol
Title: Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
Volume: 29
Issue: 10
Pages: 2582-93
Publication
First Author: Ellenrieder C
Year: 2001
Journal: DNA Cell Biol
Title: The long form of CDK2 arises via alternative splicing and forms an active protein kinase with cyclins A and E.
Volume: 20
Issue: 7
Pages: 413-23
Publication
First Author: Adon AM
Year: 2010
Journal: Mol Cell Biol
Title: Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
Volume: 30
Issue: 3
Pages: 694-710
Publication
First Author: Jayapal SR
Year: 2015
Journal: Haematologica
Title: Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress.
Volume: 100
Issue: 4
Pages: 431-8
Publication
First Author: Smartt HJ
Year: 2007
Journal: Gastroenterology
Title: p27kip1 Regulates cdk2 activity in the proliferating zone of the mouse intestinal epithelium: potential role in neoplasia.
Volume: 133
Issue: 1
Pages: 232-43
Publication
First Author: Sangwan M
Year: 2012
Journal: Oncogene
Title: Established and new mouse models reveal E2f1 and Cdk2 dependency of retinoblastoma, and expose effective strategies to block tumor initiation.
Volume: 31
Issue: 48
Pages: 5019-28
Publication
First Author: Tu Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Speedy A-Cdk2 binding mediates initial telomere-nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation.
Volume: 114
Issue: 3
Pages: 592-597
Publication
First Author: Chae U
Year: 2019
Journal: Aging (Albany NY)
Title: Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions.
Volume: 11
Issue: 17
Pages: 7242-7256
Publication
First Author: Martinerie L
Year: 2014
Journal: PLoS Genet
Title: Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis.
Volume: 10
Issue: 2
Pages: e1004165
Publication
First Author: Wu CL
Year: 2001
Journal: Cancer Res
Title: Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers.
Volume: 61
Issue: 19
Pages: 7325-32
Publication
First Author: Puyol M
Year: 2010
Journal: Cancer Cell
Title: A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.
Volume: 18
Issue: 1
Pages: 63-73
Publication
First Author: Barrière C
Year: 2007
Journal: Mol Oncol
Title: Mice thrive without Cdk4 and Cdk2.
Volume: 1
Issue: 1
Pages: 72-83
Publication
First Author: Ortega S
Year: 2003
Journal: Nat Genet
Title: Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.
Volume: 35
Issue: 1
Pages: 25-31
Publication
First Author: Hubbi ME
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.
Volume: 111
Issue: 32
Pages: E3325-34
Publication
First Author: Duensing A
Year: 2006
Journal: Oncogene
Title: Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication.
Volume: 25
Issue: 20
Pages: 2943-9
Publication
First Author: Shin HH
Year: 2004
Journal: Biochem Biophys Res Commun
Title: The soluble glucocorticoid-induced tumor necrosis factor receptor causes cell cycle arrest and apoptosis in murine macrophages.
Volume: 316
Issue: 1
Pages: 24-32
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Publication
First Author: Ye X
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene.
Volume: 98
Issue: 4
Pages: 1682-6
Publication
First Author: Chunder N
Year: 2012
Journal: J Immunol
Title: Cyclin-dependent kinase 2 controls peripheral immune tolerance.
Volume: 189
Issue: 12
Pages: 5659-66
Publication
First Author: Berthet C
Year: 2007
Journal: Mol Cell Biol
Title: Hematopoiesis and thymic apoptosis are not affected by the loss of Cdk2.
Volume: 27
Issue: 14
Pages: 5079-89
Publication
First Author: Horiuchi D
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways.
Volume: 109
Issue: 17
Pages: E1019-27
Publication
First Author: Xiao L
Year: 2013
Journal: Mol Biol Cell
Title: miR-29b represses intestinal mucosal growth by inhibiting translation of cyclin-dependent kinase 2.
Volume: 24
Issue: 19
Pages: 3038-46
Publication
First Author: Fautsch MP
Year: 1995
Journal: J Cell Biochem
Title: Differential regulation of p34cdc2 and p33cdk2 by transforming growth factor-beta 1 in murine mammary epithelial cells.
Volume: 58
Issue: 4
Pages: 517-26
Publication
First Author: Martins RA
Year: 2006
Journal: Eur J Neurosci
Title: Glutamate regulates retinal progenitors cells proliferation during development.
Volume: 24
Issue: 4
Pages: 969-80
Publication
First Author: Xue L
Year: 2010
Journal: J Biol Chem
Title: Coupling of the cell cycle and apoptotic machineries in developing T cells.
Volume: 285
Issue: 10
Pages: 7556-65
Publication
First Author: Deshpande AM
Year: 2009
Journal: J Biol Chem
Title: Cdk2ap1 is required for epigenetic silencing of Oct4 during murine embryonic stem cell differentiation.
Volume: 284
Issue: 10
Pages: 6043-7
Publication
First Author: Huang H
Year: 2006
Journal: Science
Title: CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage.
Volume: 314
Issue: 5797
Pages: 294-7
Publication
First Author: Said TK
Year: 1995
Journal: Carcinogenesis
Title: Cell cyclins and cyclin-dependent kinase activities in mouse mammary tumor development.
Volume: 16
Issue: 4
Pages: 823-30
Publication    
First Author: Vladar EK
Year: 2018
Journal: Elife
Title: Cyclin-dependent kinase control of motile ciliogenesis.
Volume: 7
Publication
First Author: Adhikari D
Year: 2012
Journal: Hum Mol Genet
Title: Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes.
Volume: 21
Issue: 11
Pages: 2476-84
Publication
First Author: Müller-Tidow C
Year: 2004
Journal: Mol Cell Biol
Title: The cyclin A1-CDK2 complex regulates DNA double-strand break repair.
Volume: 24
Issue: 20
Pages: 8917-28
Publication
First Author: Hara KT
Year: 2005
Journal: Dev Biol
Title: Cyclin A2-CDK2 regulates embryonic gene activation in 1-cell mouse embryos.
Volume: 286
Issue: 1
Pages: 102-13
Publication
First Author: Ullah Z
Year: 2008
Journal: Genes Dev
Title: Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity.
Volume: 22
Issue: 21
Pages: 3024-36
Publication
First Author: Moore GD
Year: 1996
Journal: Mol Reprod Dev
Title: Temporal patterns of gene expression of G1-S cyclins and cdks during the first and second mitotic cell cycles in mouse embryos.
Volume: 45
Issue: 3
Pages: 264-75
Publication
First Author: Pefani DE
Year: 2014
Journal: Nat Cell Biol
Title: RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.
Volume: 16
Issue: 10
Pages: 962-71, 1-8
Publication
First Author: Trakala M
Year: 2015
Journal: Dev Cell
Title: Functional reprogramming of polyploidization in megakaryocytes.
Volume: 32
Issue: 2
Pages: 155-67
Publication
First Author: Grimm SL
Year: 2005
Journal: J Biol Chem
Title: Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice.
Volume: 280
Issue: 43
Pages: 36301-9
Publication
First Author: Liem DA
Year: 2008
Journal: J Mol Cell Cardiol
Title: Cyclin-dependent kinase 2 signaling regulates myocardial ischemia/reperfusion injury.
Volume: 45
Issue: 5
Pages: 610-6
Publication
First Author: Polanco MJ
Year: 2016
Journal: Sci Transl Med
Title: Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy.
Volume: 8
Issue: 370
Pages: 370ra181
Publication
First Author: Jablonska B
Year: 2012
Journal: J Neurosci
Title: Oligodendrocyte regeneration after neonatal hypoxia requires FoxO1-mediated p27Kip1 expression.
Volume: 32
Issue: 42
Pages: 14775-93
Publication
First Author: Kim YH
Year: 1994
Journal: J Immunol
Title: Up-regulation of c-myc induces the gene expression of the murine homologues of p34cdc2 and cyclin-dependent kinase-2 in T lymphocytes.
Volume: 152
Issue: 9
Pages: 4328-35
Publication
First Author: Maddika S
Year: 2009
Journal: Mol Cell Biol
Title: Unscheduled Akt-triggered activation of cyclin-dependent kinase 2 as a key effector mechanism of apoptin's anticancer toxicity.
Volume: 29
Issue: 5
Pages: 1235-48
Publication
First Author: Wang CY
Year: 2013
Journal: Mol Cell Biol
Title: Steroidogenic factor 1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-dependent protein kinase activation.
Volume: 33
Issue: 3
Pages: 476-84
Publication
First Author: Otto J
Year: 2023
Journal: Cell Death Dis
Title: Expression of Cyclin E1 in hepatic stellate cells is critical for the induction and progression of liver fibrosis and hepatocellular carcinoma in mice.
Volume: 14
Issue: 8
Pages: 549
Publication
First Author: Aleem E
Year: 2005
Journal: Nat Cell Biol
Title: Cdc2-cyclin E complexes regulate the G1/S phase transition.
Volume: 7
Issue: 8
Pages: 831-6
Publication
First Author: Wang GL
Year: 2004
Journal: Genes Dev
Title: Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity.
Volume: 18
Issue: 8
Pages: 912-25
Publication
First Author: Zou Y
Year: 2013
Journal: J Cell Biol
Title: CUL4B promotes replication licensing by up-regulating the CDK2-CDC6 cascade.
Volume: 200
Issue: 6
Pages: 743-56
Publication
First Author: Ravnik SE
Year: 1999
Journal: Dev Biol
Title: Regulation of meiosis during mammalian spermatogenesis: the A-type cyclins and their associated cyclin-dependent kinases are differentially expressed in the germ-cell lineage.
Volume: 207
Issue: 2
Pages: 408-18
Publication  
First Author: Barbacid M
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Cell cycle and cancer: genetic analysis of the role of cyclin-dependent kinases.
Volume: 70
Pages: 233-40
Publication
First Author: Atanasoski S
Year: 2008
Journal: Mol Cell Neurosci
Title: Postnatal Schwann cell proliferation but not myelination is strictly and uniquely dependent on cyclin-dependent kinase 4 (cdk4).
Volume: 37
Issue: 3
Pages: 519-27