|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 155 for Cdk5rap2

<< First    < Previous  |  Next >    Last >>
0.051s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: CDK5 regulatory subunit-associated protein 2 (CDK5RAP2) is a centrosomal protein that regulates centrosomal maturation by recruitment of a gamma-tubulin ring complex (gamma-TuRC) onto centrosomes []. It interacts directly with EB1, a prototypic member of microtubule plus-end tracking proteins. The CDK5RAP2-EB1 complex regulates microtubule dynamics and stability []. CDK5RAP2 also interacts with Cep169, a microtubule plus-end-tracking centrosomal protein; this interaction regulates stability of microtubules []. Mutations in the CDK5RAP2 gene cause microcephaly 3, primary, autosomal recessive (MCPH3) [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:3821384
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3826112
Age: embryonic day 14.5
Image: Additional file 4 Cdk5rap2
Specimen Label: Additional file 4 Cdk5rap2
Detected: false
Specimen Num: 1
Publication
First Author: Alfares A
Year: 2018
Journal: Ann Hum Genet
Title: A new association between CDK5RAP2 microcephaly and congenital cataracts.
Volume: 82
Issue: 3
Pages: 165-170
Publication
First Author: Bond J
Year: 2005
Journal: Nat Genet
Title: A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size.
Volume: 37
Issue: 4
Pages: 353-5
Publication
First Author: Zaqout S
Year: 2020
Journal: Ann Hum Genet
Title: Congenital microcephaly-linked CDK5RAP2 affects eye development.
Volume: 84
Issue: 1
Pages: 87-91
Publication
First Author: Fong KW
Year: 2009
Journal: Mol Biol Cell
Title: Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics.
Volume: 20
Issue: 16
Pages: 3660-70
Publication
First Author: Mori Y
Year: 2015
Journal: PLoS One
Title: Cep169, a Novel Microtubule Plus-End-Tracking Centrosomal Protein, Binds to CDK5RAP2 and Regulates Microtubule Stability.
Volume: 10
Issue: 10
Pages: e0140968
Publication
First Author: Fong KW
Year: 2008
Journal: Mol Biol Cell
Title: CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex.
Volume: 19
Issue: 1
Pages: 115-25
Publication
First Author: Barrera JA
Year: 2010
Journal: Dev Cell
Title: CDK5RAP2 regulates centriole engagement and cohesion in mice.
Volume: 18
Issue: 6
Pages: 913-26
Publication
First Author: Wang X
Year: 2021
Journal: Cell Death Dis
Title: CDK5RAP2 loss-of-function causes premature cell senescence via the GSK3β/β-catenin-WIP1 pathway.
Volume: 13
Issue: 1
Pages: 9
Publication
First Author: Lizarraga SB
Year: 2010
Journal: Development
Title: Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors.
Volume: 137
Issue: 11
Pages: 1907-17
Publication
First Author: Zaqout S
Year: 2017
Journal: Stem Cell Reports
Title: CDK5RAP2 Is Required to Maintain the Germ Cell Pool during Embryonic Development.
Volume: 8
Issue: 2
Pages: 198-204
Publication
First Author: Buchman JJ
Year: 2010
Journal: Neuron
Title: Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex.
Volume: 66
Issue: 3
Pages: 386-402
Publication
First Author: Issa L
Year: 2013
Journal: Cereb Cortex
Title: CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly.
Volume: 23
Issue: 9
Pages: 2245-60
Protein
Organism: Mus musculus/domesticus
Length: 76  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1822  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1822  
Fragment?: false
Publication
First Author: Kraemer N
Year: 2015
Journal: PLoS One
Title: Novel Alternative Splice Variants of Mouse Cdk5rap2.
Volume: 10
Issue: 8
Pages: e0136684
Publication  
First Author: Zaqout S
Year: 2019
Journal: Neurobiol Dis
Title: Altered inhibition and excitation in neocortical circuits in congenital microcephaly.
Volume: 129
Pages: 130-143
Publication
First Author: Tátrai P
Year: 2022
Journal: EMBO J
Title: Centrosome function is critical during terminal erythroid differentiation.
Volume: 41
Issue: 14
Pages: e108739
Publication
First Author: Takitoh T
Year: 2012
Journal: J Neurosci
Title: Activation of Aurora-A is essential for neuronal migration via modulation of microtubule organization.
Volume: 32
Issue: 32
Pages: 11050-66
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Russell ES
Year: 1985
Journal: Dev Biol
Title: Gametic and pleiotropic defects in mouse fetuses with Hertwig's macrocytic anemia.
Volume: 110
Issue: 2
Pages: 331-7
Publication  
First Author: Bernstein SE
Year: 1975
Journal: Jackson Lab Ann Rep
Title: Bone marrow implantation therapy in Hertwig's anemic mice.
Volume: 46
Pages: 87
Publication  
First Author: Harrison DE
Year: 1976
Journal: Jackson Lab Ann Rep
Title: Stem cell multiplication rate in W-anemic mice, and immune response of mice with Hertwig's anemia.
Volume: 47
Pages: 59
Publication      
First Author: Russell ES
Year: 1966
Title: Constitutional Diseases
Pages: 571-87
Publication
First Author: Barker JE
Year: 1995
Journal: Blood
Title: Murine Hertwig's anemia: premature death after normal bone marrow transplantation is radiation dose-dependent.
Volume: 85
Issue: 9
Pages: 2627-31
Publication  
First Author: Russell ES
Year: 1976
Journal: Jackson Lab Ann Rep
Title: Germ cell defect in Hertwig's anemic mice
Volume: 47
Pages: 89
GXD Expression
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4944943
Age: embryonic day 11.5
Image: g00382 E11.5
Note: Expression was region specific and scattered.
Specimen Label: g00382 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944943
Age: embryonic day 11.5
Image: g00382 E11.5
Specimen Label: g00382 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Note: Expression was region specific and scattered.
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944943
Age: embryonic day 11.5
Image: g00382 E11.5
Specimen Label: g00382 E11.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Note: Expression was region specific and scattered.
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944943
Age: embryonic day 11.5
Image: g00382 E11.5
Specimen Label: g00382 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944943
Age: embryonic day 11.5
Image: g00382 E11.5
Specimen Label: g00382 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3821384
Assay Type: RNA in situ
Annotation Date: 2023-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7516869
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944943
Age: embryonic day 15.5
Image: g00382 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00382 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884688
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944943
Age: postnatal day 7
Image: g00382 P7
Specimen Label: g00382 P7
Detected: true
Specimen Num: 3
Publication
First Author: Taney FH
Year: 1991
Journal: Biol Reprod
Title: The role of estrogen and relaxin in the reproductive abnormalities of mice with Hertwig's anemia.
Volume: 45
Issue: 5
Pages: 719-26
Publication
First Author: Eppig JT
Year: 1984
Journal: Blood
Title: Chromosome abnormalities in mice with Hertwig's anemia.
Volume: 64
Issue: 3
Pages: 727-32
Publication
First Author: Barker JE
Year: 2005
Journal: Exp Hematol
Title: High incidence, early onset of histiocytic sarcomas in mice with Hertwig's anemia.
Volume: 33
Issue: 10
Pages: 1118-29
Publication
First Author: Barker JE
Year: 1983
Journal: Blood
Title: Hertwig's anemia: characterization of the stem cell defect.
Volume: 61
Issue: 4
Pages: 765-9
Protein
Organism: Mus musculus/domesticus
Length: 366  
Fragment?: true
Publication
First Author: Wang X
Year: 2020
Journal: Reproduction
Title: CEP215 and AURKA regulate spindle pole focusing and aMTOC organization in mouse oocytes.
Volume: 159
Issue: 3
Pages: 261-274
Publication    
First Author: Russell ES
Year: 1970
Title: Abnormalities of erythropoiesis associated with mutant genes in mice
Volume: 1
Pages: 649-75
Publication  
First Author: Bannerman RM
Year: 1973
Journal: Prog Hematol
Title: Hereditary disorders of the red cell in animals.
Volume: 8
Pages: 131-79
Publication
First Author: Sassa S
Year: 1978
Journal: Exp Hematol
Title: Studies of erythrocyte protoporphyrin in anemic mutant mice: use of a modified hematofluorometer for the detection of heterozygotes for hemolytic disease.
Volume: 6
Issue: 5
Pages: 479-87
Publication
First Author: Hertwig P
Year: 1942
Journal: Z Indukt Abstamm Vererbungsl
Title: Neue Mutationen und Koppelungsgruppen bei der Hausmaus
Volume: 80
Issue: 1
Pages: 220-246
Publication
First Author: Gao FJ
Year: 2017
Journal: Mol Biol Cell
Title: Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.
Volume: 28
Issue: 5
Pages: 587-599
Publication      
First Author: Russell ES
Year: 1966
Title: Blood and Blood Formation
Pages: 351-72
Publication      
First Author: Bernstein SE
Year: 1969
Title: Hereditary disorders of the rodent erythron
Pages: 9-33