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Search results 1 to 100 out of 296 for Cdk8

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Westerling T
Year: 2007
Journal: Mol Cell Biol
Title: Cdk8 is essential for preimplantation mouse development.
Volume: 27
Issue: 17
Pages: 6177-82
Publication      
First Author: Fisher D
Year: 2013
Journal: MGI Direct Data Submission
Title: Direct Data Submission Cdk8 Allele.
Publication
First Author: Witalisz-Siepracka A
Year: 2018
Journal: Cancer Immunol Res
Title: NK Cell-Specific CDK8 Deletion Enhances Antitumor Responses.
Volume: 6
Issue: 4
Pages: 458-466
Publication
First Author: Menzl I
Year: 2019
Journal: Nat Commun
Title: A kinase-independent role for CDK8 in BCR-ABL1+ leukemia.
Volume: 10
Issue: 1
Pages: 4741
Publication
First Author: Steinparzer I
Year: 2019
Journal: Mol Cell
Title: Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions.
Volume: 76
Issue: 3
Pages: 485-499.e8
Publication
First Author: Yamada T
Year: 2022
Journal: Stem Cell Reports
Title: The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.
Volume: 17
Issue: 7
Pages: 1576-1588
Publication
First Author: Bancerek J
Year: 2013
Journal: Immunity
Title: CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.
Volume: 38
Issue: 2
Pages: 250-62
Publication  
First Author: Dannappel MV
Year: 2022
Journal: J Clin Invest
Title: CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.
Volume: 132
Issue: 20
Publication
First Author: Prieto S
Year: 2023
Journal: EMBO Rep
Title: CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium.
Volume: 24
Issue: 2
Pages: e54261
Publication
First Author: Xue J
Year: 2019
Journal: Cell Rep
Title: CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic β Cells.
Volume: 28
Issue: 11
Pages: 2892-2904.e7
Publication
First Author: McCleland ML
Year: 2015
Journal: J Pathol
Title: Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis.
Volume: 237
Issue: 4
Pages: 508-19
Publication  
First Author: Postlmayr A
Year: 2020
Journal: Development
Title: Cdk8 is required for establishment of H3K27me3 and gene repression by Xist and mouse development.
Volume: 147
Issue: 11
Publication  
First Author: Xi X
Year: 2020
Journal: Int Immunopharmacol
Title: MiR-297 alleviates LPS-induced A549 cell and mice lung injury via targeting cyclin dependent kinase 8.
Volume: 80
Pages: 106197
Publication  
First Author: Xu D
Year: 2015
Journal: Nat Commun
Title: Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis.
Volume: 6
Pages: 6641
Publication
First Author: Li N
Year: 2014
Journal: Nat Cell Biol
Title: Cyclin C is a haploinsufficient tumour suppressor.
Volume: 16
Issue: 11
Pages: 1080-91
Publication
First Author: Porter DC
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.
Volume: 109
Issue: 34
Pages: 13799-804
Publication
First Author: Lynch CJ
Year: 2020
Journal: Nat Cell Biol
Title: Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.
Volume: 22
Issue: 10
Pages: 1223-1238
Publication
First Author: Alarcón C
Year: 2009
Journal: Cell
Title: Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.
Volume: 139
Issue: 4
Pages: 757-69
Publication
First Author: Feng D
Year: 2015
Journal: PLoS One
Title: mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC).
Volume: 10
Issue: 6
Pages: e0126240
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2007-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:3761007
Age: embryonic day 11.5
Note: Widespread ubiquitous expression.
Specimen Label: 1F
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7608360
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3265122
Stage: TS22
Assay Id: MGI:7608373
Age: embryonic day 14.5
Specimen Label: 2-8
Detected: false
Specimen Num: 1
Publication
First Author: Putz EM
Year: 2013
Journal: Cell Rep
Title: CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance.
Volume: 4
Issue: 3
Pages: 437-44
Publication
First Author: Tomomori-Sato C
Year: 2004
Journal: J Biol Chem
Title: A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.
Volume: 279
Issue: 7
Pages: 5846-51
Publication
First Author: Ahuja HS
Year: 1997
Journal: Dev Genet
Title: Association of cyclin-dependent kinase 5 and its activator p35 with apoptotic cell death.
Volume: 21
Issue: 4
Pages: 258-67
Publication
First Author: Jang MK
Year: 2005
Journal: Mol Cell
Title: The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.
Volume: 19
Issue: 4
Pages: 523-34
Publication
First Author: Aranda-Orgilles B
Year: 2016
Journal: Cell Stem Cell
Title: MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.
Volume: 19
Issue: 6
Pages: 784-799
Publication
First Author: Ponce JM
Year: 2020
Journal: J Am Heart Assoc
Title: Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics.
Volume: 9
Issue: 7
Pages: e014366
Publication
First Author: Malik S
Year: 2004
Journal: Mol Cell Biol
Title: Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.
Volume: 24
Issue: 18
Pages: 8244-54
Publication  
First Author: Campbell GJ
Year: 2020
Journal: Int J Mol Sci
Title: The Role of CDKs and CDKIs in Murine Development.
Volume: 21
Issue: 15
Publication
First Author: Xie L
Year: 2012
Journal: Dev Cell
Title: Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.
Volume: 23
Issue: 2
Pages: 280-91
Publication
First Author: Kagey MH
Year: 2010
Journal: Nature
Title: Mediator and cohesin connect gene expression and chromatin architecture.
Volume: 467
Issue: 7314
Pages: 430-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: true
UniProt Feature
Begin: 5
Description: Phosphoserine; by CDK8
Type: modified residue
End: 5
UniProt Feature
Begin: 304
Description: Phosphoserine; by CDK8
Type: modified residue
End: 304
GO Term