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Search results 1 to 99 out of 99 for Cep135

0.031s

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
9662 | CEP135
Type: gene
Organism: human
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Gene
509483 | CEP135
Type: gene
Organism: cattle
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Gene
422746 | CEP135
Type: gene
Organism: chicken
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Gene
553303 | cep135
Type: gene
Organism: zebrafish
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Gene
696309 | CEP135
Type: gene
Organism: macaque, rhesus
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Gene
100145056 | cep135
Type: gene
Organism: frog, western clawed
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Gene
305288 | Cep135
Type: gene
Organism: rat
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Gene
482157 | CEP135
Type: gene
Organism: dog, domestic
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Gene
461311 | CEP135
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2681869 | Cep135
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR026732 | Cep135
Type: Family
Description: Centrosomal protein of 135kDa (Cep135) is a centrosomal protein involved in centriole biogenesis. It acts as a scaffolding protein during early centriole biogenesis. It is also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole [, ].
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Protein
Q6P5D4
Organism: Mus musculus/domesticus
Length: 1140  
Fragment?: false
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Publication
38062802 | J:345032
First Author: Wang K
Year: 2023
Journal: Front Biosci (Landmark Ed)
Title: Centrosomal Protein CEP135 Regulates the Migration and Angiogenesis of Endothelial Cells in a Microtubule-Dependent Manner.
Volume: 28
Issue: 11
Pages: 303
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Publication
18851962 | -
First Author: Kim K
Year: 2008
Journal: Exp Cell Res
Title: A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization.
Volume: 314
Issue: 20
Pages: 3692-700
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GXD Expression
GXD Expression
 
Probe: MGI:6202376
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6202516
Age: embryonic day 7.5-7.75
Note: The centriolar protein Cep135 was detected in cilia-assembling and cilia-disassembling cells, where it co-localized with Pifo.
Specimen Label: 4C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6202376
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6202516
Age: embryonic day 7.5-7.75
Note: Cep135 was detected in cilia-assembling cells, where it co-localized with Pifo.
Specimen Label: 4D cilia assembly left
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6202376
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6202516
Age: embryonic day 7.5-7.75
Note: Cep135 was detected in cilia-disassembling cells, where it co-localized with Pifo.
Specimen Label: 4D cilia disassembly left
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6202376
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6202516
Age: embryonic day 7.5-7.75
Note: Cep135 was detected in cilia-disassembling cells, where it co-localized with Pifo.
Specimen Label: 4D cilia disassembly right
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6202376
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:6202516
Age: embryonic day 7.5-7.75
Note: In ventral node pit cells,the centriolar protein Cep135 colocalized with Pifo.
Specimen Label: 4E ventral node pit cells 1
Detected: true
Specimen Num: 5
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Protein
Q3UVI6
Organism: Mus musculus/domesticus
Length: 1031  
Fragment?: false
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Publication
17681131 | -
First Author: Kleylein-Sohn J
Year: 2007
Journal: Dev Cell
Title: Plk4-induced centriole biogenesis in human cells.
Volume: 13
Issue: 2
Pages: 190-202
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Protein Coding Gene
MGP_CAROLIEiJ_G0027318 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029646 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029614 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029562 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2681869 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030077 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029315 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029460 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029421 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029449 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030110 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028477 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028834 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017098 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028312 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
26346620 | J:233978
 
First Author: Mizuno S
Year: 2015
Journal: Sci Rep
Title: Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation.
Volume: 5
Pages: 13632
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Publication
20643351 | J:162627
First Author: Kinzel D
Year: 2010
Journal: Dev Cell
Title: Pitchfork regulates primary cilia disassembly and left-right asymmetry.
Volume: 19
Issue: 1
Pages: 66-77
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Publication
28923932 | J:256929
First Author: Otto T
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit.
Volume: 114
Issue: 40
Pages: 10660-10665
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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GXD Expression
GXD Expression
 
Probe: MGI:6202368
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6202410
Age: embryonic day 7.5-7.75
Note: Pifo colocalized with the centriolar marker Cep135 in cilia-assembling cells.
Specimen Label: 4D cilia assembly left
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:6202368
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6202410
Age: embryonic day 7.5-7.75
Note: Pifo colocalized with the centriolar marker Cep135 in cilia-disassembling cells.
Specimen Label: 4D cilia disassembly left
Detected: true
Specimen Num: 12
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Publication
14983524 | -
First Author: Uetake Y
Year: 2004
Journal: Cell Motil Cytoskeleton
Title: Interaction of Cep135 with a p50 dynactin subunit in mammalian centrosomes.
Volume: 58
Issue: 1
Pages: 53-66
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Allele
Cep135<em1Smoc> | MGI:7288931
Name: centrosomal protein 135; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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DO Term
DOID:0070282 | primary autosomal recessive microcephaly 8
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GXD Expression
GXD Expression
 
Probe: MGI:6202368
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6202410
Age: embryonic day 7.5-7.75
Note: Pifo colocalized with the centriolar marker Cep135 in cilia-assembling and cilia-disassembling cells, but was absent from the basal body of primary ciliated node cells.
Specimen Label: 4C
Detected: true
Specimen Num: 9
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Publication
26675238 | J:233615
First Author: Kurtulmus B
Year: 2016
Journal: J Cell Sci
Title: WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis.
Volume: 129
Issue: 3
Pages: 621-36
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Publication
34237032 | J:310617
 
First Author: González-Martínez J
Year: 2021
Journal: JCI Insight
Title: Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias.
Volume: 6
Issue: 16
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Publication
22349705 | J:197278
First Author: Vulprecht J
Year: 2012
Journal: J Cell Sci
Title: STIL is required for centriole duplication in human cells.
Volume: 125
Issue: Pt 5
Pages: 1353-62
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Publication
11941369 | J:78051
First Author: Collin GB
Year: 2002
Journal: Nat Genet
Title: Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndrome.
Volume: 31
Issue: 1
Pages: 74-8
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Publication
22693585 | J:187422
First Author: Collin GB
Year: 2012
Journal: PLoS One
Title: The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.
Volume: 7
Issue: 5
Pages: e37925
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Publication
27185865 | -
First Author: Chang CW
Year: 2016
Journal: J Cell Sci
Title: CEP295 interacts with microtubules and is required for centriole elongation.
Volume: 129
Issue: 13
Pages: 2501-13
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Publication
32965218 | -
   
First Author: Chen C
Year: 2020
Journal: Elife
Title: Alstrom syndrome gene is a stem-cell-specific regulator of centriole duplication in the Drosophila testis.
Volume: 9
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Publication
32060285 | -
First Author: Atorino ES
Year: 2020
Journal: Nat Commun
Title: CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion.
Volume: 11
Issue: 1
Pages: 903
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Protein Domain
IPR029299 | ALMS_motif
Type: Domain
Description: This domain is found at the C terminus of centrosome-associated protein ALMS1, centrosomal protein of 295 kDa (CEP295, also known as KIAA1731) and (E2-independent) E3 ubiquitin-conjugating enzyme FATS (also known as C10orf90) [, ]. These proteins play a role in centrosomal functions. ALMS1 is implicated in ciliary function, cell cycle control, and intracellular transport. It interacts with alpha-actinin and components of the endosomal recycling pathway []. CEP295 is a centriole-enriched microtubule-binding protein involved in centriole biogenesis, essential for the generation of the distal portion of newborn centrioles and recruitment of centriolar proteins, such as POC1B, POC5 and CEP135 [, ].Centrosome-associated protein Alms1a, the Drosophila homologue of centrosome-associated protein ALMS1, plays critical role in ensuring centrosome duplication in asymmetrically dividing germline stem cells (GSCs), which is essential for the production of centrosomes and centrioles in all downstream germ cells []. This domain directly interacts with Klp10, a microtubule-depolymerizing kinesin of kinesin-13 family, at GSC centrosome []. Alms1a might recruit SAK for daughter centriole duplication [].
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Protein
Q8K4E0
Organism: Mus musculus/domesticus
Length: 3251  
Fragment?: false
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Protein
D2J0Y4
Organism: Mus musculus/domesticus
Length: 644  
Fragment?: false
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Protein
G3UZF7
Organism: Mus musculus/domesticus
Length: 691  
Fragment?: false
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Protein
Q3ULM5
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: true
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Protein
A0A1D5RMI8
Organism: Mus musculus/domesticus
Length: 3720  
Fragment?: false
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Protein
G3UZA2
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: true
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Protein
Q9D4E0
Organism: Mus musculus/domesticus
Length: 285  
Fragment?: false
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Publication
20844083 | -
First Author: Knorz VJ
Year: 2010
Journal: Mol Biol Cell
Title: Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731.
Volume: 21
Issue: 21
Pages: 3617-29
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom