| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao L |
| Year: |
2011 |
| Journal: |
PLoS Genet |
| Title: |
A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
e1002063 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sridevi P |
| Year: |
2010 |
| Journal: |
Exp Cell Res |
| Title: |
Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing. |
| Volume: |
316 |
| Issue: |
1 |
| Pages: |
78-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen W |
| Year: |
2021 |
| Journal: |
Int J Oral Sci |
| Title: |
Downregulation of ceramide synthase 1 promotes oral cancer through endoplasmic reticulum stress. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Turpin-Nolan SM |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. |
| Volume: |
26 |
| Issue: |
1 |
| Pages: |
1-10.e7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Spassieva SD |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency. |
| Volume: |
113 |
| Issue: |
21 |
| Pages: |
5928-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ginkel C |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes. |
| Volume: |
287 |
| Issue: |
50 |
| Pages: |
41888-902 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sridevi P |
| Year: |
2009 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Ceramide synthase 1 is regulated by proteasomal mediated turnover. |
| Volume: |
1793 |
| Issue: |
7 |
| Pages: |
1218-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sugimoto M |
| Year: |
2015 |
| Journal: |
Biochim Biophys Acta |
| Title: |
Histological analyses by matrix-assisted laser desorption/ionization-imaging mass spectrometry reveal differential localization of sphingomyelin molecular species regulated by particular ceramide synthase in mouse brains. |
| Volume: |
1851 |
| Issue: |
12 |
| Pages: |
1554-65 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Spassieva S |
| Year: |
2006 |
| Journal: |
J Biol Chem |
| Title: |
Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity. |
| Volume: |
281 |
| Issue: |
45 |
| Pages: |
33931-8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543484 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752524 |
|
| Stage: |
TS24 |
| Assay Id: |
MGI:7543516 |
| Age: |
embryonic day 16.5 |
|
|
| Specimen Label: |
a E16.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543484 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752525 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:7543516 |
| Age: |
embryonic day 17.5 |
|
|
| Specimen Label: |
b E17.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7543484 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752526 |
|
| Stage: |
TS26 |
| Assay Id: |
MGI:7543516 |
| Age: |
embryonic day 18.5 |
|
|
| Specimen Label: |
c E18.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1706828 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692354 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133254 |
|
| Specimen Label: |
MRC Harwell_2133254 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692354 |
| Age: |
postnatal adult |
| Image: |
MRC Harwell_2133253 |
|
| Specimen Label: |
MRC Harwell_2133253 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lahiri S |
| Year: |
2007 |
| Journal: |
FEBS Lett |
| Title: |
Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine. |
| Volume: |
581 |
| Issue: |
27 |
| Pages: |
5289-94 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee SJ |
| Year: |
1991 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure. |
| Volume: |
88 |
| Issue: |
10 |
| Pages: |
4250-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee SJ |
| Year: |
1990 |
| Journal: |
Mol Endocrinol |
| Title: |
Identification of a novel member (GDF-1) of the transforming growth factor-beta superfamily. |
| Volume: |
4 |
| Issue: |
7 |
| Pages: |
1034-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mizutani Y |
| Year: |
2005 |
| Journal: |
Biochem J |
| Title: |
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides. |
| Volume: |
390 |
| Issue: |
Pt 1 |
| Pages: |
263-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Novgorodov SA |
| Year: |
2016 |
| Journal: |
J Biol Chem |
| Title: |
SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY. |
| Volume: |
291 |
| Issue: |
4 |
| Pages: |
1957-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Duchala CS |
| Year: |
2004 |
| Journal: |
J Comp Neurol |
| Title: |
The toppler mouse: a novel mutant exhibiting loss of Purkinje cells. |
| Volume: |
476 |
| Issue: |
2 |
| Pages: |
113-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Clarke D |
| Year: |
2001 |
| Journal: |
Mamm Genome |
| Title: |
Comparative analysis of human 19p12-13 region in Fugu and mouse. |
| Volume: |
12 |
| Issue: |
6 |
| Pages: |
478-83 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang J |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
2315 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Z |
| Year: |
2013 |
| Journal: |
J Invest Dermatol |
| Title: |
Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. |
| Volume: |
133 |
| Issue: |
3 |
| Pages: |
668-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lau CG |
| Year: |
2014 |
| Journal: |
Mol Reprod Dev |
| Title: |
Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil. |
| Volume: |
81 |
| Issue: |
11 |
| Pages: |
994-1008 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientfic Curators |
| Year: |
2013 |
|
| Title: |
Curated associations of genes in MGI and UniProt sequence records |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koscielny G |
| Year: |
2014 |
| Journal: |
Nucleic Acids Res |
| Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
| Volume: |
42 |
| Issue: |
Database issue |
| Pages: |
D802-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Knockout Mouse Consortium |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Mouse Strain Resource |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
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•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
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|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
350
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Turner N |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
3165 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Laperrousaz E |
| Year: |
2017 |
| Journal: |
Diabetologia |
| Title: |
Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice. |
| Volume: |
60 |
| Issue: |
7 |
| Pages: |
1314-1324 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schwartz NU |
| Year: |
2018 |
| Journal: |
FASEB J |
| Title: |
Decreased ceramide underlies mitochondrial dysfunction in Charcot-Marie-Tooth 2F. |
| Volume: |
32 |
| Issue: |
3 |
| Pages: |
1716-1728 |
|
•
•
•
•
•
|