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Search results 1 to 100 out of 142 for Cers2

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0.03s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Raichur S
Year: 2014
Journal: Cell Metab
Title: CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance.
Volume: 20
Issue: 4
Pages: 687-95
Publication
First Author: Bickert A
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division.
Volume: 1863
Issue: 7
Pages: 734-749
Publication
First Author: Pewzner-Jung Y
Year: 2010
Journal: J Biol Chem
Title: A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways.
Volume: 285
Issue: 14
Pages: 10902-10
Publication
First Author: Imgrund S
Year: 2009
Journal: J Biol Chem
Title: Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas.
Volume: 284
Issue: 48
Pages: 33549-60
Publication
First Author: Zigdon H
Year: 2013
Journal: J Biol Chem
Title: Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain.
Volume: 288
Issue: 7
Pages: 4947-56
Publication
First Author: Petrache I
Year: 2013
Journal: PLoS One
Title: Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models.
Volume: 8
Issue: 5
Pages: e62968
Publication
First Author: Park WJ
Year: 2014
Journal: Biochim Biophys Acta
Title: Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length.
Volume: 1841
Issue: 12
Pages: 1754-66
Publication
First Author: Marsching C
Year: 2014
Journal: J Lipid Res
Title: Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.
Volume: 55
Issue: 11
Pages: 2354-69
Publication
First Author: Kim YR
Year: 2017
Journal: J Cell Mol Med
Title: Ablation of ceramide synthase 2 exacerbates dextran sodium sulphate-induced colitis in mice due to increased intestinal permeability.
Volume: 21
Issue: 12
Pages: 3565-3578
Publication
First Author: Volpert G
Year: 2017
Journal: J Cell Sci
Title: Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis.
Volume: 130
Issue: 8
Pages: 1486-1493
Publication
First Author: Ali M
Year: 2015
Journal: FEBS Lett
Title: LPS-mediated septic shock is augmented in ceramide synthase 2 null mice due to elevated activity of TNFα-converting enzyme.
Volume: 589
Issue: 17
Pages: 2213-7
Publication
First Author: Rieck M
Year: 2017
Journal: Eur J Immunol
Title: Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice.
Volume: 47
Issue: 4
Pages: 677-684
Publication
First Author: Spassieva SD
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency.
Volume: 113
Issue: 21
Pages: 5928-33
Publication
First Author: Sugimoto M
Year: 2015
Journal: Biochim Biophys Acta
Title: Histological analyses by matrix-assisted laser desorption/ionization-imaging mass spectrometry reveal differential localization of sphingomyelin molecular species regulated by particular ceramide synthase in mouse brains.
Volume: 1851
Issue: 12
Pages: 1554-65
Publication
First Author: Kremser C
Year: 2013
Journal: Histochem Cell Biol
Title: Cell-type-specific expression pattern of ceramide synthase 2 protein in mouse tissues.
Volume: 140
Issue: 5
Pages: 533-47
Publication
First Author: Park WJ
Year: 2013
Journal: J Biol Chem
Title: Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization.
Volume: 288
Issue: 43
Pages: 30904-16
Publication
First Author: Silva LC
Year: 2012
Journal: J Lipid Res
Title: Ablation of ceramide synthase 2 strongly affects biophysical properties of membranes.
Volume: 53
Issue: 3
Pages: 430-6
Publication
First Author: Sassa T
Year: 2016
Journal: J Biol Chem
Title: Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.
Volume: 291
Issue: 14
Pages: 7477-87
Publication
First Author: Choi S
Year: 2016
Journal: Aging Cell
Title: KCa 3.1 upregulation preserves endothelium-dependent vasorelaxation during aging and oxidative stress.
Volume: 15
Issue: 5
Pages: 801-10
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Hla T
Year: 2014
Journal: Cell Metab
Title: C16:0-ceramide signals insulin resistance.
Volume: 20
Issue: 5
Pages: 703-5
Publication
First Author: Ben-David O
Year: 2011
Journal: J Biol Chem
Title: Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels.
Volume: 286
Issue: 34
Pages: 30022-33
Publication
First Author: Lu X
Year: 2014
Journal: Oncol Rep
Title: Knockout of the HCC suppressor gene Lass2 downregulates the expression level of miR-694.
Volume: 32
Issue: 6
Pages: 2696-702
Publication
First Author: Jin H
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Liver-specific deletion of LASS2 delayed regeneration of mouse liver after partial hepatectomy.
Volume: 493
Issue: 3
Pages: 1176-1183
Publication
First Author: Chen L
Year: 2014
Journal: Oncol Rep
Title: Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis.
Volume: 31
Issue: 2
Pages: 885-93
Publication  
First Author: Fan S
Year: 2018
Journal: Free Radic Biol Med
Title: Hepatocyte-specific deletion of LASS2 protects against diet-induced hepatic steatosis and insulin resistance.
Volume: 120
Pages: 330-341
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:4818960
Age: embryonic day 17.0
Image: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:4818960
Age: postnatal day 0
Image: 1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal day 7
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 1
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 2
Image: 1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 3
Image: 1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 4
Image: 1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 5
Image: 1
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 6
Image: 1
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 10
Image: 1
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5824380
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278626
Stage: TS26
Assay Id: MGI:5824516
Age: embryonic day 18.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4845159
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848843
Age: embryonic day 11.5
Note: Staining is present in the antero-proximal and posterior-proximal regions of the limb.
Detected: true
Specimen Num: 2
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4818963
Age: postnatal month 5
Image: 5A
Note: Expression is in the portal triad region and to a lesser extent in the centrilobular region.
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4818963
Age: postnatal month 5
Image: 5B
Note: Expression is in the portal triad region and to a lesser extent in the centrilobular region.
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5824380
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5824516
Age: embryonic day 18.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4845159
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4848843
Age: embryonic day 9.5
Note: Staining is present in the medial neural tube.
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5824380
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5824516
Age: embryonic day 18.5
Detected: true
Specimen Num: 1
Publication
First Author: Pewzner-Jung Y
Year: 2010
Journal: J Biol Chem
Title: A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy.
Volume: 285
Issue: 14
Pages: 10911-23
Publication
First Author: Sassa T
Year: 2013
Journal: Mol Cell Biol
Title: Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.
Volume: 33
Issue: 14
Pages: 2787-96
Publication
First Author: Jennemann R
Year: 2012
Journal: Hum Mol Genet
Title: Loss of ceramide synthase 3 causes lethal skin barrier disruption.
Volume: 21
Issue: 3
Pages: 586-608
Publication
First Author: Pewzner-Jung Y
Year: 2014
Journal: EMBO Mol Med
Title: Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.
Volume: 6
Issue: 9
Pages: 1205-14
Publication
First Author: Mizumura K
Year: 2018
Journal: FASEB J
Title: Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure.
Volume: 32
Issue: 4
Pages: 1880-1890
Publication
First Author: Novgorodov SA
Year: 2016
Journal: J Biol Chem
Title: SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.
Volume: 291
Issue: 4
Pages: 1957-73
Publication
First Author: Yamashita-Sugahara Y
Year: 2013
Journal: J Biol Chem
Title: Fam57b (family with sequence similarity 57, member B), a novel peroxisome proliferator-activated receptor γ target gene that regulates adipogenesis through ceramide synthesis.
Volume: 288
Issue: 7
Pages: 4522-37
Publication
First Author: Mizutani Y
Year: 2005
Journal: Biochem J
Title: Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.
Volume: 390
Issue: Pt 1
Pages: 263-71
Publication
First Author: Yang Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: LASS2 regulates hepatocyte steatosis by interacting with NDUFS2/OXPHOS related proteins.
Volume: 526
Issue: 4
Pages: 871-879
Publication
First Author: Paget C
Year: 2019
Journal: PLoS Biol
Title: TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells.
Volume: 17
Issue: 3
Pages: e3000169
Publication
First Author: Pichery M
Year: 2017
Journal: Hum Mol Genet
Title: PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.
Volume: 26
Issue: 10
Pages: 1787-1800
Publication
First Author: Wang Z
Year: 2013
Journal: J Invest Dermatol
Title: Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.
Volume: 133
Issue: 3
Pages: 668-76
Publication
First Author: Lau CG
Year: 2014
Journal: Mol Reprod Dev
Title: Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.
Volume: 81
Issue: 11
Pages: 994-1008
Publication
First Author: Li S
Year: 2017
Journal: Sci Rep
Title: Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.
Volume: 7
Issue: 1
Pages: 13427
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms