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Search results 1 to 100 out of 172 for Cers2

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Raichur S
Year: 2014
Journal: Cell Metab
Title: CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance.
Volume: 20
Issue: 4
Pages: 687-95
Publication
First Author: Bickert A
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division.
Volume: 1863
Issue: 7
Pages: 734-749
Publication
First Author: McNally BD
Year: 2022
Journal: Nat Commun
Title: Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle.
Volume: 13
Issue: 1
Pages: 1748
Publication
First Author: Imgrund S
Year: 2009
Journal: J Biol Chem
Title: Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas.
Volume: 284
Issue: 48
Pages: 33549-60
Publication
First Author: Pewzner-Jung Y
Year: 2010
Journal: J Biol Chem
Title: A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways.
Volume: 285
Issue: 14
Pages: 10902-10
Publication
First Author: Kim YR
Year: 2017
Journal: J Cell Mol Med
Title: Ablation of ceramide synthase 2 exacerbates dextran sodium sulphate-induced colitis in mice due to increased intestinal permeability.
Volume: 21
Issue: 12
Pages: 3565-3578
Publication
First Author: Zigdon H
Year: 2013
Journal: J Biol Chem
Title: Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain.
Volume: 288
Issue: 7
Pages: 4947-56
Publication
First Author: Park WJ
Year: 2014
Journal: Biochim Biophys Acta
Title: Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length.
Volume: 1841
Issue: 12
Pages: 1754-66
Publication
First Author: Volpert G
Year: 2017
Journal: J Cell Sci
Title: Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis.
Volume: 130
Issue: 8
Pages: 1486-1493
Publication
First Author: Petrache I
Year: 2013
Journal: PLoS One
Title: Ceramide synthases expression and role of ceramide synthase-2 in the lung: insight from human lung cells and mouse models.
Volume: 8
Issue: 5
Pages: e62968
Publication
First Author: Marsching C
Year: 2014
Journal: J Lipid Res
Title: Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.
Volume: 55
Issue: 11
Pages: 2354-69
Publication  
First Author: Shin SH
Year: 2021
Journal: Int J Mol Sci
Title: Ceramide Synthase 2 Null Mice Are Protected from Ovalbumin-Induced Asthma with Higher T Cell Receptor Signal Strength in CD4+ T Cells.
Volume: 22
Issue: 5
Publication  
First Author: Barthelmes J
Year: 2015
Journal: Brain Behav Immun
Title: Lack of ceramide synthase 2 suppresses the development of experimental autoimmune encephalomyelitis by impairing the migratory capacity of neutrophils.
Volume: 46
Pages: 280-92
Publication
First Author: Oertel S
Year: 2017
Journal: Cell Mol Life Sci
Title: Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity.
Volume: 74
Issue: 16
Pages: 3039-3055
Publication
First Author: Ali M
Year: 2015
Journal: FEBS Lett
Title: LPS-mediated septic shock is augmented in ceramide synthase 2 null mice due to elevated activity of TNFα-converting enzyme.
Volume: 589
Issue: 17
Pages: 2213-7
Publication
First Author: Rieck M
Year: 2017
Journal: Eur J Immunol
Title: Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice.
Volume: 47
Issue: 4
Pages: 677-684
Publication
First Author: Spassieva SD
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency.
Volume: 113
Issue: 21
Pages: 5928-33
Publication
First Author: Kremser C
Year: 2013
Journal: Histochem Cell Biol
Title: Cell-type-specific expression pattern of ceramide synthase 2 protein in mouse tissues.
Volume: 140
Issue: 5
Pages: 533-47
Publication
First Author: Park WJ
Year: 2013
Journal: J Biol Chem
Title: Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization.
Volume: 288
Issue: 43
Pages: 30904-16
Publication
First Author: Silva LC
Year: 2012
Journal: J Lipid Res
Title: Ablation of ceramide synthase 2 strongly affects biophysical properties of membranes.
Volume: 53
Issue: 3
Pages: 430-6
Publication
First Author: Sugimoto M
Year: 2015
Journal: Biochim Biophys Acta
Title: Histological analyses by matrix-assisted laser desorption/ionization-imaging mass spectrometry reveal differential localization of sphingomyelin molecular species regulated by particular ceramide synthase in mouse brains.
Volume: 1851
Issue: 12
Pages: 1554-65
Publication
First Author: Sassa T
Year: 2016
Journal: J Biol Chem
Title: Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.
Volume: 291
Issue: 14
Pages: 7477-87
Publication
First Author: Kurz J
Year: 2019
Journal: Sci Rep
Title: Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes.
Volume: 9
Issue: 1
Pages: 747
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lu X
Year: 2014
Journal: Oncol Rep
Title: Knockout of the HCC suppressor gene Lass2 downregulates the expression level of miR-694.
Volume: 32
Issue: 6
Pages: 2696-702
Publication
First Author: Chen L
Year: 2014
Journal: Oncol Rep
Title: Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis.
Volume: 31
Issue: 2
Pages: 885-93
Publication  
First Author: Fan S
Year: 2018
Journal: Free Radic Biol Med
Title: Hepatocyte-specific deletion of LASS2 protects against diet-induced hepatic steatosis and insulin resistance.
Volume: 120
Pages: 330-341
Publication
First Author: Jin H
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Liver-specific deletion of LASS2 delayed regeneration of mouse liver after partial hepatectomy.
Volume: 493
Issue: 3
Pages: 1176-1183
Publication
First Author: Ben-David O
Year: 2011
Journal: J Biol Chem
Title: Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels.
Volume: 286
Issue: 34
Pages: 30022-33
Publication
First Author: Hla T
Year: 2014
Journal: Cell Metab
Title: C16:0-ceramide signals insulin resistance.
Volume: 20
Issue: 5
Pages: 703-5
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:4818960
Age: embryonic day 17.0
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:4818960
Age: postnatal day 0
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal day 7
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 1
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 2
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 3
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 4
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 6
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:4818959
Assay Type: RT-PCR
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4818960
Age: postnatal month 10
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7461605
Assay Type: RT-PCR
Annotation Date: 2023-04-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:7461627
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7461605
Assay Type: RT-PCR
Annotation Date: 2023-04-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:7461627
Age: embryonic day 18.5
Specimen Label: Pnpla1 tm1a
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7543485
Assay Type: RT-PCR
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752524
Stage: TS24
Assay Id: MGI:7543518
Age: embryonic day 16.5
Specimen Label: a E16.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7543485
Assay Type: RT-PCR
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:7543518
Age: embryonic day 17.5
Specimen Label: b E17.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7543485
Assay Type: RT-PCR
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:7543518
Age: embryonic day 18.5
Specimen Label: c E18.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7543482
Assay Type: Western blot
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Stage: TS26
Assay Id: MGI:7543549
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7543482
Assay Type: Western blot
Annotation Date: 2023-10-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Stage: TS26
Assay Id: MGI:7543549
Age: embryonic day 18.5
Specimen Label: Ctip2-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7543485
Assay Type: RT-PCR
Annotation Date: 2023-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:7547199
Age: embryonic day 18.5
Image: 5
Specimen Label: Ctip1+/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7543485
Assay Type: RT-PCR
Annotation Date: 2023-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752526
Stage: TS26
Assay Id: MGI:7547199
Age: embryonic day 18.5
Image: 5
Specimen Label: Ctip1-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5824380
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278626
Stage: TS26
Assay Id: MGI:5824516
Age: embryonic day 18.5
Specimen Label: 6A
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4845159
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848843
Age: embryonic day 11.5
Note: Staining is present in the antero-proximal and posterior-proximal regions of the limb.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1413001
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526590
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4818963
Age: postnatal month 5
Image: 5A
Note: Expression is in the portal triad region and to a lesser extent in the centrilobular region.
Specimen Label: 5A
Detected: true
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2010-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4818963
Age: postnatal month 5
Image: 5B
Note: Expression is in the portal triad region and to a lesser extent in the centrilobular region.
Specimen Label: 5B
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5824380
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5824516
Age: embryonic day 18.5
Specimen Label: 6A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4845159
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4848843
Age: embryonic day 9.5
Note: Staining is present in the medial neural tube.
Specimen Label: Table S4 - E9.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1413001
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526590
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the cortical plate.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5824380
Assay Type: RNA in situ
Annotation Date: 2017-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5824516
Age: embryonic day 18.5
Specimen Label: 6A
Detected: true
Specimen Num: 1
Publication
First Author: Pewzner-Jung Y
Year: 2010
Journal: J Biol Chem
Title: A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy.
Volume: 285
Issue: 14
Pages: 10911-23
Publication
First Author: Choi S
Year: 2016
Journal: Aging Cell
Title: KCa 3.1 upregulation preserves endothelium-dependent vasorelaxation during aging and oxidative stress.
Volume: 15
Issue: 5
Pages: 801-10
Publication
First Author: Sassa T
Year: 2013
Journal: Mol Cell Biol
Title: Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.
Volume: 33
Issue: 14
Pages: 2787-96
Publication
First Author: Jennemann R
Year: 2012
Journal: Hum Mol Genet
Title: Loss of ceramide synthase 3 causes lethal skin barrier disruption.
Volume: 21
Issue: 3
Pages: 586-608
Publication
First Author: Pewzner-Jung Y
Year: 2014
Journal: EMBO Mol Med
Title: Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.
Volume: 6
Issue: 9
Pages: 1205-14
Publication
First Author: Mizumura K
Year: 2018
Journal: FASEB J
Title: Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure.
Volume: 32
Issue: 4
Pages: 1880-1890
Publication
First Author: Mizutani Y
Year: 2005
Journal: Biochem J
Title: Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.
Volume: 390
Issue: Pt 1
Pages: 263-71
Publication
First Author: Novgorodov SA
Year: 2016
Journal: J Biol Chem
Title: SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.
Volume: 291
Issue: 4
Pages: 1957-73
Publication
First Author: Yamashita-Sugahara Y
Year: 2013
Journal: J Biol Chem
Title: Fam57b (family with sequence similarity 57, member B), a novel peroxisome proliferator-activated receptor γ target gene that regulates adipogenesis through ceramide synthesis.
Volume: 288
Issue: 7
Pages: 4522-37
Publication
First Author: Paget C
Year: 2019
Journal: PLoS Biol
Title: TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells.
Volume: 17
Issue: 3
Pages: e3000169
Publication
First Author: Yang Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: LASS2 regulates hepatocyte steatosis by interacting with NDUFS2/OXPHOS related proteins.
Volume: 526
Issue: 4
Pages: 871-879
Publication
First Author: Alatibi KI
Year: 2020
Journal: FEBS J
Title: Sex-specific perturbation of complex lipids in response to medium-chain fatty acids in very long-chain acyl-CoA dehydrogenase deficiency.
Volume: 287
Issue: 16
Pages: 3511-3525
Publication
First Author: Pichery M
Year: 2017
Journal: Hum Mol Genet
Title: PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.
Volume: 26
Issue: 10
Pages: 1787-1800
Publication
First Author: Wang Z
Year: 2013
Journal: J Invest Dermatol
Title: Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.
Volume: 133
Issue: 3
Pages: 668-76
Publication
First Author: Zhang J
Year: 2024
Journal: Nat Commun
Title: Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.
Volume: 15
Issue: 1
Pages: 2315