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Search results 1 to 100 out of 714 for Cfh

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
3075 | CFH
Type: gene
Organism: human
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Gene
280816 | CFH
Type: gene
Organism: cattle
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Gene
429057 | CFH
Type: gene
Organism: chicken
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Gene
553297 | cfh
Type: gene
Organism: zebrafish
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Gene
717346 | CFH
Type: gene
Organism: macaque, rhesus
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Gene
394826 | cfh
Type: gene
Organism: frog, western clawed
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Gene
155012 | Cfh
Type: gene
Organism: rat
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Gene
478952 | CFH
Type: gene
Organism: dog, domestic
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Gene
457601 | CFH
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:88385 | Cfh
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:2380154
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3274322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3825936
Age: embryonic day 14.5
Image: Additional file 4 Cfh
Note: Expression was in the vasculature of the pancreas.
Specimen Label: Additional file 4 Cfh
Detected: true
Specimen Num: 1
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Publication
35942101 | J:327293
First Author: Serra CFH
Year: 2022
Journal: iScience
Title: Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.
Volume: 25
Issue: 8
Pages: 104751
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Publication
24370827 | J:229141
First Author: Rowan S
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice.
Volume: 55
Issue: 1
Pages: 492-501
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Publication
25447048 | J:216960
First Author: Ding JD
Year: 2015
Journal: Am J Pathol
Title: Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice.
Volume: 185
Issue: 1
Pages: 29-42
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Publication
26030099 | J:230961
First Author: Aredo B
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice.
Volume: 56
Issue: 6
Pages: 3427-40
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Author
Serra CFH
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Publication
17517971 | J:125860
First Author: Pickering MC
Year: 2007
Journal: J Exp Med
Title: Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains.
Volume: 204
Issue: 6
Pages: 1249-56
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Publication
21148255 | J:185883
First Author: de Jorge EG
Year: 2011
Journal: J Am Soc Nephrol
Title: The development of atypical hemolytic uremic syndrome depends on complement C5.
Volume: 22
Issue: 1
Pages: 137-45
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Protein
Q61407
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: true
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Protein
Q8R0I8
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: false
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Protein
Q61405
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: false
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Publication
29895552 | J:291005
First Author: Wang X
Year: 2018
Journal: J Am Soc Nephrol
Title: Prevention of Fatal C3 Glomerulopathy by Recombinant Complement Receptor of the Ig Superfamily.
Volume: 29
Issue: 8
Pages: 2053-2059
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Publication
30025090 | J:263946
First Author: Song D
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease.
Volume: 59
Issue: 8
Pages: 3405-3415
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Publication
23487775 | J:242465
First Author: Goicoechea de Jorge E
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Dimerization of complement factor H-related proteins modulates complement activation in vivo.
Volume: 110
Issue: 12
Pages: 4685-90
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Publication
37499656 | J:341063
First Author: Kiss MG
Year: 2023
Journal: Immunity
Title: Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis.
Volume: 56
Issue: 8
Pages: 1809-1824.e10
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Publication
31133737 | J:279758
First Author: Zoshima T
Year: 2019
Journal: Sci Rep
Title: Possible role of complement factor H in podocytes in clearing glomerular subendothelial immune complex deposits.
Volume: 9
Issue: 1
Pages: 7857
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Publication
23184055 | J:318823
First Author: Ruseva MM
Year: 2013
Journal: J Am Soc Nephrol
Title: Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency.
Volume: 24
Issue: 1
Pages: 43-52
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Publication
34775843 | J:341290
First Author: Feng L
Year: 2022
Journal: Exp Biol Med (Maywood)
Title: Complement factor H deficiency combined with smoking promotes retinal degeneration in a novel mouse model.
Volume: 247
Issue: 2
Pages: 77-86
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Publication
28819420 | J:257103
First Author: Liu J
Year: 2017
Journal: J Cancer
Title: Loss of Complement Factor H in Plasma Increases Endothelial Cell Migration.
Volume: 8
Issue: 12
Pages: 2184-2190
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Publication
25991857 | J:223294
First Author: Toomey CB
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Regulation of age-related macular degeneration-like pathology by complement factor H.
Volume: 112
Issue: 23
Pages: E3040-9
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Publication
20445496 | J:184266
First Author: Fakhouri F
Year: 2010
Journal: Kidney Int
Title: Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice.
Volume: 78
Issue: 3
Pages: 279-86
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Publication
31354740 | J:284412
 
First Author: Kiss MG
Year: 2019
Journal: Front Immunol
Title: Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production.
Volume: 10
Pages: 1607
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Publication
30705315 | J:275920
First Author: Sivapathasuntharam C
Year: 2019
Journal: Sci Rep
Title: Complement factor H regulates retinal development and its absence may establish a footprint for age related macular degeneration.
Volume: 9
Issue: 1
Pages: 1082
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Publication
33859044 | J:316268
 
First Author: Acker N
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia.
Volume: 118
Issue: 16
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Publication
17921253 | J:125991
First Author: Coffey PJ
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction.
Volume: 104
Issue: 42
Pages: 16651-6
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Publication
16597679 | J:135742
First Author: Alexander JJ
Year: 2006
Journal: J Am Soc Nephrol
Title: Distinct and separable roles of the complement system in factor H-deficient bone marrow chimeric mice with immune complex disease.
Volume: 17
Issue: 5
Pages: 1354-61
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Publication
20702729 | J:163836
First Author: Alexander JJ
Year: 2010
Journal: J Immunol
Title: Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.
Volume: 185
Issue: 6
Pages: 3759-67
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Publication
23844226 | J:204297
First Author: Williams JA
Year: 2013
Journal: PLoS One
Title: Retinal changes precede visual dysfunction in the complement factor H knockout mouse.
Volume: 8
Issue: 7
Pages: e68616
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Publication
19541934 | J:149983
First Author: Lundh von Leithner P
Year: 2009
Journal: Am J Pathol
Title: Complement factor h is critical in the maintenance of retinal perfusion.
Volume: 175
Issue: 1
Pages: 412-21
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Publication
20538999 | J:171400
First Author: Ufret-Vincenty RL
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings.
Volume: 51
Issue: 11
Pages: 5878-87
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Publication
20813971 | J:165433
First Author: Lyzogubov VV
Year: 2010
Journal: Am J Pathol
Title: Role of ocular complement factor H in a murine model of choroidal neovascularization.
Volume: 177
Issue: 4
Pages: 1870-80
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Publication
22875704 | J:188589
First Author: Shaw PX
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids.
Volume: 109
Issue: 34
Pages: 13757-62
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Publication
30642982 | J:272929
First Author: Chen X
Year: 2019
Journal: J Immunol
Title: Cadmium Induces Glomerular Endothelial Cell-Specific Expression of Complement Factor H via the -1635 AP-1 Binding Site.
Volume: 202
Issue: 4
Pages: 1210-1218
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Publication
30808757 | J:272759
First Author: Landowski M
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.
Volume: 116
Issue: 9
Pages: 3703-3711
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Publication
2564419 | J:9676
First Author: Kingsmore SF
Year: 1989
Journal: J Exp Med
Title: Genetic organization of complement receptor-related genes in the mouse.
Volume: 169
Issue: 4
Pages: 1479-84
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Publication
22832515 | J:198407
First Author: Alexander JJ
Year: 2012
Journal: Kidney Int
Title: The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice.
Volume: 82
Issue: 9
Pages: 961-8
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Publication
32369457 | J:293954
First Author: Laskowski J
Year: 2020
Journal: J Clin Invest
Title: Complement factor H-deficient mice develop spontaneous hepatic tumors.
Volume: 130
Issue: 8
Pages: 4039-4054
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Publication
23747511 | J:198723
First Author: Hoh Kam J
Year: 2013
Journal: Am J Pathol
Title: Complement component C3 plays a critical role in protecting the aging retina in a murine model of age-related macular degeneration.
Volume: 183
Issue: 2
Pages: 480-92
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Publication
27918307 | J:239848
First Author: Keir LS
Year: 2017
Journal: J Clin Invest
Title: VEGF regulates local inhibitory complement proteins in the eye and kidney.
Volume: 127
Issue: 1
Pages: 199-214
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Publication
28228282 | J:254528
First Author: Calippe B
Year: 2017
Journal: Immunity
Title: Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation.
Volume: 46
Issue: 2
Pages: 261-272
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Publication
37940659 | J:342359
First Author: Nielsen MK
Year: 2023
Journal: Sci Rep
Title: Complement factor H Y402H polymorphism results in diminishing CD4(+) T cells and increasing C-reactive protein in plasma.
Volume: 13
Issue: 1
Pages: 19414
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Publication
25684976 | J:344654
 
First Author: Smit-McBride Z
Year: 2015
Journal: Mol Vis
Title: Localization of complement factor H gene expression and protein distribution in the mouse outer retina.
Volume: 21
Pages: 110-23
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Publication
21148254 | J:185884
First Author: Bao L
Year: 2011
Journal: J Am Soc Nephrol
Title: Complement factor H deficiency accelerates development of lupus nephritis.
Volume: 22
Issue: 2
Pages: 285-95
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Publication
29070671 | J:251563
First Author: Kane SJ
Year: 2017
Journal: J Immunol
Title: Complement Regulatory Protein Factor H Is a Soluble Prion Receptor That Potentiates Peripheral Prion Pathogenesis.
Volume: 199
Issue: 11
Pages: 3821-3827
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Publication
22918646 | J:214059
First Author: Faber C
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Complement factor H deficiency results in decreased neuroretinal expression of Cd59a in aged mice.
Volume: 53
Issue: 10
Pages: 6324-30
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Publication
2878046 | J:8488
First Author: D'Eustachio P
Year: 1986
Journal: J Immunol
Title: Chromosomal location of the genes encoding complement components C5 and factor H in the mouse.
Volume: 137
Issue: 12
Pages: 3990-5
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Publication
31409673 | J:280397
First Author: Zheng L
Year: 2019
Journal: Blood
Title: Synergistic effects of ADAMTS13 deficiency and complement activation in pathogenesis of thrombotic microangiopathy.
Volume: 134
Issue: 13
Pages: 1095-1105
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Publication
19411110 | J:149558
First Author: Paixão-Cavalcante D
Year: 2009
Journal: Mol Immunol
Title: Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phase.
Volume: 46
Issue: 10
Pages: 1942-50
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Publication
27564415 | J:250675
First Author: Williams JA
Year: 2016
Journal: PLoS One
Title: Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina.
Volume: 11
Issue: 8
Pages: e0161898
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Publication
23204401 | J:264171
First Author: Lesher AM
Year: 2013
Journal: J Am Soc Nephrol
Title: Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.
Volume: 24
Issue: 1
Pages: 53-65
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Publication
17028856 | J:116059
First Author: Hellwage J
Year: 2006
Journal: Immunogenetics
Title: Two factor H-related proteins from the mouse: expression analysis and functional characterization.
Volume: 58
Issue: 11
Pages: 883-93
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Publication
1689298 | J:61605
First Author: Vik DP
Year: 1990
Journal: J Biol Chem
Title: Identification and sequence analysis of four complement factor H-related transcripts in mouse liver.
Volume: 265
Issue: 6
Pages: 3193-201
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Protein Coding Gene
MGP_CAROLIEiJ_G0014671 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_AJ_G0016541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016506 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88385 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016962 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015905 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016406 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016404 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016477 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016430 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015691 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015968 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027906 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015478 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2940596 | J:8307
First Author: Kristensen T
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Murine protein H is comprised of 20 repeating units, 61 amino acids in length.
Volume: 83
Issue: 11
Pages: 3963-7
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Publication
30107932 | J:308603
First Author: Alexander JJ
Year: 2018
Journal: Immunobiology
Title: Absence of complement factor H alters bone architecture and dynamics.
Volume: 223
Issue: 12
Pages: 761-771
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Publication
23133374 | J:195365
First Author: Johnson S
Year: 2012
Journal: PLoS Pathog
Title: Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules.
Volume: 8
Issue: 10
Pages: e1002981
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Publication
29858280 | J:293121
First Author: Ueda Y
Year: 2018
Journal: J Am Soc Nephrol
Title: Blocking Properdin Prevents Complement-Mediated Hemolytic Uremic Syndrome and Systemic Thrombophilia.
Volume: 29
Issue: 7
Pages: 1928-1937
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Publication
26374608 | J:293180
First Author: Vernon KA
Year: 2016
Journal: J Am Soc Nephrol
Title: Partial Complement Factor H Deficiency Associates with C3 Glomerulopathy and Thrombotic Microangiopathy.
Volume: 27
Issue: 5
Pages: 1334-42
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Publication
32849636 | J:308196
 
First Author: Merle NS
Year: 2020
Journal: Front Immunol
Title: Circulating FH Protects Kidneys From Tubular Injury During Systemic Hemolysis.
Volume: 11
Pages: 1772
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Publication
24929970 | J:218073
First Author: Cunea A
Year: 2014
Journal: Neurobiol Aging
Title: Death by color: differential cone loss in the aging mouse retina.
Volume: 35
Issue: 11
Pages: 2584-2591
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Publication
25921262 | J:230331
 
First Author: Hoh Kam J
Year: 2015
Journal: Exp Eye Res
Title: Topical cyclodextrin reduces amyloid beta and inflammation improving retinal function in ageing mice.
Volume: 135
Pages: 59-66
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Publication
26149919 | J:235549
First Author: Calaza KC
Year: 2015
Journal: Neurobiol Aging
Title: Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but can be corrected by near infrared light.
Volume: 36
Issue: 10
Pages: 2869-76
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Publication
29392311 | J:256968
First Author: Toomey CB
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Effect of Anti-C5a Therapy in a Murine Model of Early/Intermediate Dry Age-Related Macular Degeneration.
Volume: 59
Issue: 2
Pages: 662-673
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Publication
33558624 | J:313757
First Author: Kaynezhad P
Year: 2021
Journal: Sci Rep
Title: Watching synchronous mitochondrial respiration in the retina and its instability in a mouse model of macular degeneration.
Volume: 11
Issue: 1
Pages: 3274
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Publication
23436934 | J:194744
First Author: Banda NK
Year: 2013
Journal: J Immunol
Title: Essential role of surface-bound complement factor H in controlling immune complex-induced arthritis.
Volume: 190
Issue: 7
Pages: 3560-9
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Publication
15574507 | J:110085
First Author: Alexander JJ
Year: 2005
Journal: J Am Soc Nephrol
Title: Complement factor h limits immune complex deposition and prevents inflammation and scarring in glomeruli of mice with chronic serum sickness.
Volume: 16
Issue: 1
Pages: 52-7
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Publication
32737203 | J:298927
First Author: Kelly UL
Year: 2020
Journal: J Biol Chem
Title: High-density lipoproteins are a potential therapeutic target for age-related macular degeneration.
Volume: 295
Issue: 39
Pages: 13601-13616
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Publication
23799019 | J:203471
First Author: Catchpole I
Year: 2013
Journal: PLoS One
Title: Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model.
Volume: 8
Issue: 6
Pages: e65518
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Publication
23469078 | J:198270
First Author: Begum R
Year: 2013
Journal: PLoS One
Title: Treatment with 670 nm light up regulates cytochrome C oxidase expression and reduces inflammation in an age-related macular degeneration model.
Volume: 8
Issue: 2
Pages: e57828
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Publication
34054871 | J:314531
 
First Author: Kerr H
Year: 2021
Journal: Front Immunol
Title: Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice.
Volume: 12
Pages: 681098
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Publication
27397653 | J:278415
 
First Author: Hoh Kam J
Year: 2016
Journal: Exp Eye Res
Title: Aged complement factor H knockout mice kept in a clean barriered environment have reduced retinal pathology.
Volume: 149
Pages: 116-125
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Publication
29389016 | J:263176
First Author: Goetz L
Year: 2018
Journal: Eur J Immunol
Title: Complement factor H protects mice from ischemic acute kidney injury but is not critical for controlling complement activation by glomerular IgM.
Volume: 48
Issue: 5
Pages: 791-802
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Publication
32376801 | J:301746
 
First Author: Zhang Y
Year: 2020
Journal: JCI Insight
Title: C3(H2O) prevents rescue of complement-mediated C3 glomerulopathy in Cfh-/- Cfd-/- mice.
Volume: 5
Issue: 9
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Publication
17410102 | J:136905
First Author: Abrera-Abeleda MA
Year: 2007
Journal: Kidney Int
Title: Mesangial immune complex glomerulonephritis due to complement factor D deficiency.
Volume: 71
Issue: 11
Pages: 1142-7
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Publication
21544060 | J:194806
First Author: Renner B
Year: 2011
Journal: Kidney Int
Title: Binding of factor H to tubular epithelial cells limits interstitial complement activation in ischemic injury.
Volume: 80
Issue: 2
Pages: 165-73
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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