Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
CGG triplet repeat-binding protein 1 (CGGBP1) is a repetitive DNA-binding transcription regulator with target sites at CpG-rich sequences such as CGG repeats and Alu-SINEs and L1-LINEs []. CGGBP1 mitigates cytosine methylation at repetitive DNA sequences []. It also functions in DNA damage/repair and telomere metabolism []. There are indications that it may be involved in mRNA metabolism []. CGGBP1 ensures CTCF occupancy preferentially on repeats over canonical CTCF motifs, being a regulator of CTCF and its binding sites in interspersed repeats [].CGGBP1/p20 is known to bind to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the in the promoter of the fragile X messenger ribonucleoprotein 1 (FMR1/FMRP) gene [, ], although it seems not to have a direct effect on FMR1 transcription []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh U |
Year: |
2014 |
Journal: |
Cell Cycle |
Title: |
CGGBP1 phosphorylation constitutes a telomere-protection signal. |
Volume: |
13 |
Issue: |
1 |
Pages: |
96-105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patel D |
Year: |
2019 |
Journal: |
Epigenetics Chromatin |
Title: |
CGGBP1 regulates CTCF occupancy at repeats. |
Volume: |
12 |
Issue: |
1 |
Pages: |
57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Agarwal P |
Year: |
2016 |
Journal: |
Cell Cycle |
Title: |
Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs. |
Volume: |
15 |
Issue: |
12 |
Pages: |
1558-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Agarwal P |
Year: |
2015 |
Journal: |
BMC Genomics |
Title: |
CGGBP1 mitigates cytosine methylation at repetitive DNA sequences. |
Volume: |
16 |
|
Pages: |
390 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goracci M |
Year: |
2016 |
Journal: |
Eur J Hum Genet |
Title: |
Defining the role of the CGGBP1 protein in FMR1 gene expression. |
Volume: |
24 |
Issue: |
5 |
Pages: |
697-703 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
167
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Deissler H |
Year: |
1997 |
Journal: |
J Biol Chem |
Title: |
Rapid protein sequencing by tandem mass spectrometry and cDNA cloning of p20-CGGBP. A novel protein that binds to the unstable triplet repeat 5'-d(CGG)n-3' in the human FMR1 gene. |
Volume: |
272 |
Issue: |
27 |
Pages: |
16761-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Müller-Hartmann H |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
The human 20-kDa 5'-(CGG)(n)-3'-binding protein is targeted to the nucleus and affects the activity of the FMR1 promoter. |
Volume: |
275 |
Issue: |
9 |
Pages: |
6447-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh U |
Year: |
2015 |
Journal: |
Ups J Med Sci |
Title: |
CGGBP1--an indispensable protein with ubiquitous cytoprotective functions. |
Volume: |
120 |
Issue: |
4 |
Pages: |
219-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Naumann F |
Year: |
2004 |
Journal: |
Genomics |
Title: |
Gene structure and expression of the 5'-(CGG)(n)-3'-binding protein (CGGBP1). |
Volume: |
83 |
Issue: |
1 |
Pages: |
106-18 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3038934 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603910 |
|
Stage: |
TS10 |
Assay Id: |
MGI:3038947 |
Age: |
embryonic day 7.0 |
|
|
Specimen Label: |
day 7 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3038934 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603918 |
|
Stage: |
TS18 |
Assay Id: |
MGI:3038947 |
Age: |
embryonic day 11.0 |
|
|
Specimen Label: |
day 11 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3038934 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603923 |
|
Stage: |
TS23 |
Assay Id: |
MGI:3038947 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
day 15 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3038934 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603925 |
|
Stage: |
TS25 |
Assay Id: |
MGI:3038947 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
day 17 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3510744 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-12-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:3510807 |
Age: |
embryonic day 10.5 |
Image: |
2 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3510744 |
Assay Type: |
RT-PCR |
Annotation Date: |
2004-12-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3510807 |
Age: |
embryonic day 13.5 |
Image: |
2 |
|
Specimen Label: |
None |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3510834 |
Assay Type: |
Northern blot |
Annotation Date: |
2004-12-14 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3510857 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Ear |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ficker M |
Year: |
2004 |
Journal: |
Dev Biol |
Title: |
Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule. |
Volume: |
268 |
Issue: |
1 |
Pages: |
7-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamatani T |
Year: |
2004 |
Journal: |
Hum Mol Genet |
Title: |
Age-associated alteration of gene expression patterns in mouse oocytes. |
Volume: |
13 |
Issue: |
19 |
Pages: |
2263-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bulfone A |
Year: |
2005 |
Journal: |
J Neurosci |
Title: |
Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. |
Volume: |
25 |
Issue: |
33 |
Pages: |
7586-600 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
|
Title: |
Human to Mouse ISO GO annotation transfer |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
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•
•
•
•
•
|