Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
pig, domestic |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4438726 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-09-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7525612 |
Age: |
postnatal adult |
Image: |
S1D ChAT |
Note: |
Expression in cholinergic amacrine cells. |
Specimen Label: |
S1D ChAT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Erickson CS |
Year: |
2014 |
Journal: |
Neurogastroenterol Motil |
Title: |
Appearance of cholinergic myenteric neurons during enteric nervous system development: comparison of different ChAT fluorescent mouse reporter lines. |
Volume: |
26 |
Issue: |
6 |
Pages: |
874-84 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Some proteins containing this domain appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169710 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6189966 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Chat |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169710 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6189966 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Chat |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169710 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6189966 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Chat |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169710 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6189966 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Chat |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169710 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189966 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Chat |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169710 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189966 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Chat |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6169710 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189966 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Chat |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
702
 |
Fragment?: |
false |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6099117 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2017-12-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:6100932 |
Age: |
postnatal adult |
Image: |
4N |
Note: |
Authors report co-localization with Chat in most starburst amacrine cells. |
Specimen Label: |
4N |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4402753 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-05-29 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3671019 |
|
Stage: |
TS19 |
Assay Id: |
MGI:7643450 |
Age: |
embryonic day 11.5 |
Image: |
S4N |
Note: |
Conditional ablation of Twist1 produces abnormal cellular aggregates. Expression of Chat was not above background levels in the aggregates. |
Specimen Label: |
S4N |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klug JR |
Year: |
2018 |
Journal: |
Elife |
Title: |
Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions. |
Volume: |
7 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shostak DM |
Year: |
2023 |
Journal: |
Front Endocrinol (Lausanne) |
Title: |
Acetylcholine regulation of GnRH neuronal activity: A circuit in the medial septum. |
Volume: |
14 |
|
Pages: |
1147554 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chase KA |
Year: |
2019 |
Journal: |
PLoS One |
Title: |
Examining the effects of the histone methyltransferase inhibitor BIX-01294 on histone modifications and gene expression in both a clinical population and mouse models. |
Volume: |
14 |
Issue: |
6 |
Pages: |
e0216463 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen E |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Altered Baseline and Nicotine-Mediated Behavioral and Cholinergic Profiles in ChAT-Cre Mouse Lines. |
Volume: |
38 |
Issue: |
9 |
Pages: |
2177-2188 |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeong JH |
Year: |
2017 |
Journal: |
Mol Metab |
Title: |
Cholinergic neurons in the dorsomedial hypothalamus regulate food intake. |
Volume: |
6 |
Issue: |
3 |
Pages: |
306-312 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeong JH |
Year: |
2015 |
Journal: |
Mol Metab |
Title: |
Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism. |
Volume: |
4 |
Issue: |
6 |
Pages: |
483-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Severino AL |
Year: |
2020 |
Journal: |
eNeuro |
Title: |
μ-Opioid Receptors on Distinct Neuronal Populations Mediate Different Aspects of Opioid Reward-Related Behaviors. |
Volume: |
7 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Quaresma PGF |
Year: |
2020 |
Journal: |
Life Sci |
Title: |
Cholinergic neurons in the hypothalamus and dorsal motor nucleus of the vagus are directly responsive to growth hormone. |
Volume: |
259 |
|
Pages: |
118229 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dudai A |
Year: |
2020 |
Journal: |
PLoS Biol |
Title: |
Barrel cortex VIP/ChAT interneurons suppress sensory responses in vivo. |
Volume: |
18 |
Issue: |
2 |
Pages: |
e3000613 |
|
•
•
•
•
•
|
ncRNA Gene |
Type: |
lncRNA_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Lecomte MJ |
Year: |
2014 |
Journal: |
Neurobiol Dis |
Title: |
Selective disruption of acetylcholine synthesis in subsets of motor neurons: a new model of late-onset motor neuron disease. |
Volume: |
65 |
|
Pages: |
102-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Richter F |
Year: |
2019 |
Journal: |
EBioMedicine |
Title: |
Optogenetic augmentation of the hypercholinergic endophenotype in DYT1 knock-in mice induced erratic hyperactive movements but not dystonia. |
Volume: |
41 |
|
Pages: |
649-658 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pang JJ |
Year: |
2013 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Survey on amacrine cells coupling to retrograde-identified ganglion cells in the mouse retina. |
Volume: |
54 |
Issue: |
8 |
Pages: |
5151-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Herrera JA |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Methyl-CpG binding-protein 2 function in cholinergic neurons mediates cardiac arrhythmogenesis. |
Volume: |
25 |
Issue: |
22 |
Pages: |
4983-4995 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jaiswal PB |
Year: |
2017 |
Journal: |
J Neurosci Res |
Title: |
Motoneuron activity is required for enhancements in functional recovery after peripheral nerve injury in exercised female mice. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Childs JE |
Year: |
2024 |
Journal: |
Cell Rep |
Title: |
Relapse to cocaine seeking is regulated by medial habenula NR4A2/NURR1 in mice. |
Volume: |
43 |
Issue: |
3 |
Pages: |
113956 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rehani R |
Year: |
2019 |
Journal: |
eNeuro |
Title: |
Activity Patterns in the Neuropil of Striatal Cholinergic Interneurons in Freely Moving Mice Represent Their Collective Spiking Dynamics. |
Volume: |
6 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lee J |
Year: |
2016 |
Journal: |
Neuron |
Title: |
Linking Cholinergic Interneurons, Synaptic Plasticity, and Behavior during the Extinction of a Cocaine-Context Association. |
Volume: |
90 |
Issue: |
5 |
Pages: |
1071-1085 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zucca S |
Year: |
2018 |
Journal: |
Elife |
Title: |
Pauses in cholinergic interneuron firing exert an inhibitory control on striatal output in vivo. |
Volume: |
7 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Desikan S |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Target selectivity of septal cholinergic neurons in the medial and lateral entorhinal cortex. |
Volume: |
115 |
Issue: |
11 |
Pages: |
E2644-E2652 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hegedüs P |
Year: |
2023 |
Journal: |
iScience |
Title: |
Cholinergic activity reflects reward expectations and predicts behavioral responses. |
Volume: |
26 |
Issue: |
1 |
Pages: |
105814 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao P |
Year: |
2023 |
Journal: |
BMC Biol |
Title: |
Upper brainstem cholinergic neurons project to ascending and descending circuits. |
Volume: |
21 |
Issue: |
1 |
Pages: |
135 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toor RUAS |
Year: |
2019 |
Journal: |
J Neurosci |
Title: |
Neurons in the Intermediate Reticular Nucleus Coordinate Postinspiratory Activity, Swallowing, and Respiratory-Sympathetic Coupling in the Rat. |
Volume: |
39 |
Issue: |
49 |
Pages: |
9757-9766 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang L |
Year: |
2016 |
Journal: |
Neuron |
Title: |
Cholinergic Signaling Controls Conditioned Fear Behaviors and Enhances Plasticity of Cortical-Amygdala Circuits. |
Volume: |
90 |
Issue: |
5 |
Pages: |
1057-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen J |
Year: |
2023 |
Journal: |
Neural Regen Res |
Title: |
Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy. |
Volume: |
18 |
Issue: |
11 |
Pages: |
2459-2465 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng Y |
Year: |
2022 |
Journal: |
Int J Mol Sci |
Title: |
Basal Forebrain-Dorsal Hippocampus Cholinergic Circuit Regulates Olfactory Associative Learning. |
Volume: |
23 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cadeddu R |
Year: |
2023 |
Journal: |
Neuropsychopharmacology |
Title: |
Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology. |
Volume: |
48 |
Issue: |
9 |
Pages: |
1288-1299 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu Z |
Year: |
2024 |
Journal: |
Curr Biol |
Title: |
Performance errors during rodent learning reflect a dynamic choice strategy. |
Volume: |
34 |
Issue: |
10 |
Pages: |
2107-2117.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lhopitallier C |
Year: |
2022 |
Journal: |
PLoS One |
Title: |
Characterization of social behavior in young and middle-aged ChAT-IRES-Cre mouse. |
Volume: |
17 |
Issue: |
8 |
Pages: |
e0272141 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fore TR |
Year: |
2020 |
Journal: |
J Neurosci |
Title: |
Acetylcholine Modulates Cerebellar Granule Cell Spiking by Regulating the Balance of Synaptic Excitation and Inhibition. |
Volume: |
40 |
Issue: |
14 |
Pages: |
2882-2894 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang M |
Year: |
2021 |
Journal: |
J Cell Biol |
Title: |
Completion of neuronal remodeling prompts myelination along developing motor axon branches. |
Volume: |
220 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Aitta-Aho T |
Year: |
2017 |
Journal: |
eNeuro |
Title: |
Accumbal Cholinergic Interneurons Differentially Influence Motivation Related to Satiety Signaling. |
Volume: |
4 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson JA |
Year: |
2016 |
Journal: |
Elife |
Title: |
Mesencephalic representations of recent experience influence decision making. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ruan Y |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Cholinergic neurons in the pedunculopontine nucleus guide reversal learning by signaling the changing reward contingency. |
Volume: |
38 |
Issue: |
9 |
Pages: |
110437 |
|
•
•
•
•
•
|
Publication |
First Author: |
Biancardi V |
Year: |
2023 |
Journal: |
J Comp Neurol |
Title: |
Cholinergic projections to the preBötzinger complex. |
Volume: |
531 |
Issue: |
13 |
Pages: |
1317-1332 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson CJ |
Year: |
2024 |
Journal: |
J Neurosci Methods |
Title: |
A novel naïve Bayes approach to identifying grooming behaviors in the force-plate actometric platform. |
Volume: |
403 |
|
Pages: |
110026 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pimpinella D |
Year: |
2021 |
Journal: |
Elife |
Title: |
Septal cholinergic input to CA2 hippocampal region controls social novelty discrimination via nicotinic receptor-mediated disinhibition. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
NamKoong C |
Year: |
2019 |
Journal: |
Neurosci Lett |
Title: |
Chemogenetic manipulation of parasympathetic neurons (DMV) regulates feeding behavior and energy metabolism. |
Volume: |
712 |
|
Pages: |
134356 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martins-Silva C |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Novel strains of mice deficient for the vesicular acetylcholine transporter: insights on transcriptional regulation and control of locomotor behavior. |
Volume: |
6 |
Issue: |
3 |
Pages: |
e17611 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishii K |
Year: |
1990 |
Journal: |
Brain Res Mol Brain Res |
Title: |
Complementary DNAs for choline acetyltransferase from spinal cords of rat and mouse: nucleotide sequences, expression in mammalian cells, and in situ hybridization. |
Volume: |
7 |
Issue: |
2 |
Pages: |
151-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frahm S |
Year: |
2015 |
Journal: |
Elife |
Title: |
An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence. |
Volume: |
4 |
|
Pages: |
e11396 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ndjim M |
Year: |
2024 |
Journal: |
Immunity |
Title: |
Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity. |
Volume: |
57 |
Issue: |
6 |
Pages: |
1260-1273.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Misawa H |
Year: |
1994 |
Journal: |
J Neurochem |
Title: |
Calcium-independent release of acetylcholine from stable cell lines expressing mouse choline acetyltransferase cDNA. |
Volume: |
62 |
Issue: |
2 |
Pages: |
465-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng Y |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Postsynaptic histamine H(3) receptors in ventral basal forebrain cholinergic neurons modulate contextual fear memory. |
Volume: |
42 |
Issue: |
9 |
Pages: |
113073 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lowell BB |
Year: |
2006 |
Journal: |
MGI Direct Data Submission |
Title: |
Development and phenotype of ChAT-IRES-Cre mice |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bariselli S |
Year: |
2023 |
Journal: |
Neuropsychopharmacology |
Title: |
Gestational ethanol exposure impairs motor skills in female mice through dysregulated striatal dopamine and acetylcholine function. |
Volume: |
48 |
Issue: |
12 |
Pages: |
1808-1820 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu YX |
Year: |
2022 |
Journal: |
Biomed Pharmacother |
Title: |
Activation of cholinergic basal forebrain neurons improved cognitive functions in adult-onset hypothyroid mice. |
Volume: |
153 |
|
Pages: |
113495 |
|
•
•
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