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Search results 1 to 100 out of 148 for Chchd4

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) is a chaperone and catalyses the formation of disulfide bonds in proteins within the mitochondrial intermembrane space (IMS) such as COX17 [], COX19 [], MICU1 []and GFER []. A precursor of one of these proteins in a reduced state is imported into the mitochondrion where it associates with CHCHD4 forming a transient intermolecular disulfide bridge. This leads to oxidation of the precursor, formation of an intramolecular disulfide bond and the folding in the IMS [].This entry also includes the uncharacterized protein F42H10.2 from Caenorhabditis elegans.
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Hangen E
Year: 2015
Journal: Mol Cell
Title: Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis.
Volume: 58
Issue: 6
Pages: 1001-14
Publication
First Author: Sun Y
Year: 2017
Journal: Cell Death Dis
Title: Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia.
Volume: 8
Issue: 5
Pages: e2781
Publication
First Author: Hofmann S
Year: 2005
Journal: J Mol Biol
Title: Functional and mutational characterization of human MIA40 acting during import into the mitochondrial intermembrane space.
Volume: 353
Issue: 3
Pages: 517-28
Publication
First Author: Fischer M
Year: 2013
Journal: Mol Biol Cell
Title: Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells.
Volume: 24
Issue: 14
Pages: 2160-70
Publication
First Author: Banci L
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Molecular chaperone function of Mia40 triggers consecutive induced folding steps of the substrate in mitochondrial protein import.
Volume: 107
Issue: 47
Pages: 20190-5
Publication
First Author: Petrungaro C
Year: 2015
Journal: Cell Metab
Title: The Ca(2+)-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca(2+) Uptake.
Volume: 22
Issue: 4
Pages: 721-33
Protein
Organism: Mus musculus/domesticus
Length: 139  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false
Publication
First Author: Modjtahedi N
Year: 2015
Journal: Cell Cycle
Title: Metabolic epistasis among apoptosis-inducing factor and the mitochondrial import factor CHCHD4.
Volume: 14
Issue: 17
Pages: 2743-7
Publication
First Author: Ma J
Year: 2024
Journal: Cell Rep
Title: CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise.
Volume: 43
Issue: 1
Pages: 113626
Publication
First Author: Zhuang J
Year: 2016
Journal: J Biol Chem
Title: Forkhead Box O3A (FOXO3) and the Mitochondrial Disulfide Relay Carrier (CHCHD4) Regulate p53 Protein Nuclear Activity in Response to Exercise.
Volume: 291
Issue: 48
Pages: 24819-24827
Publication
First Author: Zhuang J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity.
Volume: 110
Issue: 43
Pages: 17356-61
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160398
Stage: TS08
Assay Id: MGI:7593892
Age: embryonic day 5.5-6.0
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160398
Stage: TS08
Assay Id: MGI:7593892
Age: embryonic day 5.5-6.0
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 5
Specimen Label: WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 5
Specimen Label: WT
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 5
Specimen Label: HQ
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 5
Specimen Label: HQ
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 5
Specimen Label: HQ
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 10
Specimen Label: WT
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 10
Specimen Label: WT
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 10
Specimen Label: WT
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 10
Specimen Label: HQ
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 10
Specimen Label: HQ
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 10
Specimen Label: HQ
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 30
Specimen Label: WT
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 30
Specimen Label: WT
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 30
Specimen Label: WT
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 30
Specimen Label: HQ
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 30
Specimen Label: HQ
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 30
Specimen Label: HQ
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 60
Specimen Label: WT
Detected: true
Specimen Num: 19
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 60
Specimen Label: WT
Detected: true
Specimen Num: 20
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 60
Specimen Label: WT
Detected: true
Specimen Num: 21
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 60
Specimen Label: HQ
Detected: true
Specimen Num: 22
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 60
Specimen Label: HQ
Detected: true
Specimen Num: 23
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593906
Age: postnatal day 60
Specimen Label: HQ
Detected: true
Specimen Num: 24
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 5
Specimen Label: WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 5
Specimen Label: HQ
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 5
Specimen Label: HQ
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 10
Specimen Label: WT
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 10
Specimen Label: WT
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 10
Specimen Label: HQ
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 10
Specimen Label: HQ
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 30
Specimen Label: WT
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 30
Specimen Label: WT
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 30
Specimen Label: HQ
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 30
Specimen Label: HQ
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 60
Specimen Label: WT
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 60
Specimen Label: WT
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 60
Specimen Label: HQ
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593940
Age: postnatal day 60
Specimen Label: HQ
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: HQ
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: HQ
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: HQ
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: HQ
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: HQ
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: HQ
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: WT
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:7587848
Assay Type: Western blot
Annotation Date: 2024-02-16
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7593946
Age: postnatal adult
Specimen Label: HQ
Detected: true
Specimen Num: 16