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Search results 1 to 93 out of 93 for Chfr

0.401s

Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
55743 | CHFR
Type: gene
Organism: human
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Gene
395009 | chfr
Type: gene
Organism: frog, western clawed
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Gene
288734 | Chfr
Type: gene
Organism: rat
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Gene
452391 | CHFR
Type: gene
Organism: chimpanzee
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Gene
477434 | CHFR
Type: gene
Organism: dog, domestic
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Gene
614816 | CHFR
Type: gene
Organism: cattle
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Gene
416792 | CHFR
Type: gene
Organism: chicken
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Gene
564271 | chfr
Type: gene
Organism: zebrafish
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Gene
694297 | CHFR
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2444898 | Chfr
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
101928530 | CHFR-DT
Type: gene
Organism: human
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Publication
15793587 | J:97428
First Author: Yu X
Year: 2005
Journal: Nat Genet
Title: Chfr is required for tumor suppression and Aurora A regulation.
Volume: 37
Issue: 4
Pages: 401-6
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Publication
21706008 | J:244705
First Author: Wu J
Year: 2011
Journal: Nat Struct Mol Biol
Title: Chfr and RNF8 synergistically regulate ATM activation.
Volume: 18
Issue: 7
Pages: 761-8
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Publication
26566864 | J:333319
First Author: Lu LY
Year: 2015
Journal: Cell Cycle
Title: CHFR is important for the survival of male premeiotic germ cells.
Volume: 14
Issue: 21
Pages: 3454-60
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Publication
19690386 | J:152704
First Author: Fu Z
Year: 2009
Journal: J Clin Invest
Title: Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.
Volume: 119
Issue: 9
Pages: 2714-24
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Publication
23268447 | J:200220
First Author: Liu C
Year: 2013
Journal: Nucleic Acids Res
Title: CHFR is important for the first wave of ubiquitination at DNA damage sites.
Volume: 41
Issue: 3
Pages: 1698-710
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Publication
22285184 | J:181256
First Author: Jung I
Year: 2012
Journal: Biochem Biophys Res Commun
Title: SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components.
Volume: 418
Issue: 3
Pages: 512-7
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Publication
21245198 | J:182879
First Author: Castiel A
Year: 2011
Journal: J Cell Sci
Title: The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr.
Volume: 124
Issue: Pt 4
Pages: 532-9
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Protein Coding Gene
MGP_CAROLIEiJ_G0027538 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029880 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029845 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029783 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029856 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029576 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2444898 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030309 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028984 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029543 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029693 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029781 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029681 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030350 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024120 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028536 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:5317856
Assay Type: Western blot
Annotation Date: 2012-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5317862
Age: embryonic day 9.5
Specimen Label: K/O
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5317856
Assay Type: Western blot
Annotation Date: 2012-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5317862
Age: embryonic day 9.5
Specimen Label: w.t
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5317856
Assay Type: Western blot
Annotation Date: 2012-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5317862
Age: embryonic day 9.5
Specimen Label: H
Detected: true
Specimen Num: 3
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q810L3
Organism: Mus musculus/domesticus
Length: 664  
Fragment?: false
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Protein
Q810L3-3
Organism: Mus musculus/domesticus
Length: 592  
Fragment?: false
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Protein
Q810L3-4
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
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Protein
Q810L3-2
Organism: Mus musculus/domesticus
Length: 663  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase CHFR
Type: chain
End: 664
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Protein
Q6A027
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: true
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Protein
A0A0G2JGX6
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: true
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Protein
A0A0G2JDG0
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: false
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Protein
A0A0G2JFC1
Organism: Mus musculus/domesticus
Length: 50  
Fragment?: false
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Protein
A0A0G2JG18
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: false
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Protein
A0A0G2JFU4
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: false
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Interaction Experiment
Wu J (2011)
Description: Chfr and RNF8 synergistically regulate ATM activation.
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Publication
11912157 | -
First Author: Chaturvedi P
Year: 2002
Journal: Cancer Res
Title: Chfr regulates a mitotic stress pathway through its RING-finger domain with ubiquitin ligase activity.
Volume: 62
Issue: 6
Pages: 1797-801
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Interaction Experiment
Yu X (2005)
Description: Chfr is required for tumor suppression and Aurora A regulation.
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Publication
18202552 | -
First Author: Loring GL
Year: 2008
Journal: Cell Cycle
Title: Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination.
Volume: 7
Issue: 1
Pages: 96-105
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Publication
12121644 | -
First Author: Stavridi ES
Year: 2002
Journal: Structure
Title: Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
Volume: 10
Issue: 7
Pages: 891-9
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Publication
20880844 | -
First Author: Oberoi J
Year: 2010
Journal: J Biol Chem
Title: Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING Domains (CHFR).
Volume: 285
Issue: 50
Pages: 39348-58
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Protein Domain
IPR040909 | CHFR_Znf-CRD
Type: Domain
Description: This is a cysteine rich domain which contains four zinc-binding regions (binding five zinc ions) found in CHFR, an E3 ubiquitin-protein ligase []. CHFR interacts with Poly(ADP-ribose) (PAR) through a 20-amino acid PAR binding zinc finger region (PBZ) found at the C-terminal end of this cysteine-rich domain (i.e. the 4th region towards the C-terminal). CHFR lacking PBZ does not co-localize with nuclear PAR foci in interphase cells and cannot rescue antephase checkpoint function despite retaining autoubiquitination activity. Hence it has been suggested that the CHFR-PAR interaction is an important part of the antephase checkpoint and could form part of the checkpoint sensor for cellular stress and microtubule poisons or be required for proper localization of CHFR. The PBZ region of CHFR contains two adenine binding sites [].
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Publication
17525332 | -
First Author: Matsuoka S
Year: 2007
Journal: Science
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
Volume: 316
Issue: 5828
Pages: 1160-6
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Publication
15368895 | J:92575
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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