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Search results 1 to 98 out of 98 for Chmp1a

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: Charged multivesicular body protein 1a (CHMP1A, also known as chromatin-modifying protein 1A) is part of the ESCRT-III complex, which is required for endosome-mediated trafficking via multivesicular body (MVB) formation and sorting []. Besides being part of the ESCRT-III complex, it is also identified as a nuclear matrix protein affecting chromatin structure and cell-cycle progression []. In humans it acts as a tumour suppressor [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:6726329
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:6726349
Age: embryonic day 14.5
Image: 2E Chmp1a
Note: No expression in progenitors.
Specimen Label: 2E Chmp1a
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:6726329
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6726349
Age: embryonic day 14.5
Image: 2E Chmp1a
Note: Expression in postmitotic neurons in cerebral cortex.
Specimen Label: 2E Chmp1a
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6726329
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522327
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6726349
Age: postnatal day 0
Image: 2B Chmp1a
Note: Expression in Purkinje cell cytoplasm and dendrites; expression absent from nucleus.
Specimen Label: 2B Chmp1a
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6726329
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3521627
Stage: TS27
Assay Id: MGI:6726349
Age: postnatal day 0
Image: 2B Chmp1a
Specimen Label: 2B Chmp1a
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:6726329
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754722
Stage: TS22
Assay Id: MGI:6726349
Age: embryonic day 14.5
Image: 2E Chmp1a
Note: No expression in progenitors.
Specimen Label: 2E Chmp1a
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:6726329
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3703827
Pattern: Punctate
Stage: TS27
Assay Id: MGI:6726349
Age: postnatal day 0
Image: S3A Chmp1a
Note: Punctate expression in epithelial cells of hindbrain choroid plexus.
Specimen Label: S3A Chmp1a
Detected: true
Specimen Num: 3
Publication
First Author: Stauffer DR
Year: 2001
Journal: J Cell Sci
Title: CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression.
Volume: 114
Issue: Pt 13
Pages: 2383-93
GXD Expression    
Probe: MGI:6726329
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778727
Stage: TS27
Assay Id: MGI:6726349
Age: postnatal day 0
Image: S3D Chmp1a null
Specimen Label: S3D Chmp1a null
Detected: false
Specimen Num: 5
Protein
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: false
Publication
First Author: Coulter ME
Year: 2018
Journal: Cell Rep
Title: The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles.
Volume: 24
Issue: 4
Pages: 973-986.e8
Publication
First Author: Li J
Year: 2008
Journal: Cell Cycle
Title: Chmp1A functions as a novel tumor suppressor gene in human embryonic kidney and ductal pancreatic tumor cells.
Volume: 7
Issue: 18
Pages: 2886-93
Publication
First Author: Manohar S
Year: 2011
Journal: Cell Cycle
Title: Chromatin modifying protein 1A (Chmp1A) of the endosomal sorting complex required for transport (ESCRT)-III family activates ataxia telangiectasia mutated (ATM) for PanC-1 cell growth inhibition.
Volume: 10
Issue: 15
Pages: 2529-39
GXD Expression
Probe: MGI:5447973
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6726346
Age: embryonic day 18.5
Image: 1E Chmp1a null
Note: Authors report cortical plate is 13% thinner compared to controls.
Specimen Label: 1E Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5447971
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6726345
Age: embryonic day 18.5
Image: 1E Ctip2 Chmp1a null
Note: Authors report cortical plate is 13% thinner than in controls.
Specimen Label: 1E Ctip2 Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5699394
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6726347
Age: embryonic day 18.5
Image: 1E Chmp1a null
Note: Authors report striatum area is reduced by 25% compared to controls.
Specimen Label: 1E Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6726332
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6726351
Age: embryonic day 13.5
Image: 3C Chmp1a null
Note: Embryos have 26% fewer intermediate progenitors compared to controls.
Specimen Label: 3C Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6725841
Assay Type: RNA in situ
Annotation Date: 2021-07-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6726343
Age: postnatal day 0
Image: 3E Chmp1a null
Note: Expression reduced in cerebellum.
Specimen Label: 3E Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5827948
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6726356
Age: embryonic day 12.5
Image: S4C Chmp1a null
Note: No detectable increase in apoptosis compared to controls.
Specimen Label: S4C Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:2681585
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6726358
Age: embryonic day 14.5
Image: S4E aPKC Chmp1a null
Note: No detectable defect in cortical ventricular surface.
Specimen Label: S4E aPKC Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:2681585
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6726359
Age: embryonic day 14.5
Image: S4E aPKC Chmp1a null
Note: No detectable defect in cortical ventricular surface.
Specimen Label: S4E aPKC Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6726336
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6726360
Age: embryonic day 14.5
Image: S5A Chmp1a null
Note: No detectable difference in faction of mitotic cells in cytokinesis.
Specimen Label: S5A Chmp1a null
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6726328
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6726348
Age: postnatal day 0
Image: S4A Chmp1a null
Note: Purkinje cell layer is intact and unchanged compared to controls.
Specimen Label: S4A Chmp1a null
Detected: true
Specimen Num: 3
Publication
First Author: Guan Y
Year: 2021
Journal: Nat Commun
Title: A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.
Volume: 12
Issue: 1
Pages: 5078
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression
Probe: MGI:7529137
Assay Type: RNA in situ
Annotation Date: 2023-09-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3642217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7529139
Age: embryonic day 10.5
Image: 4C
Note: Expression was enriched in the cranial neural crest cells (CCNC) of the trigeminal stream. Co-localization was observed with the CCNC marker, Sox10.
Specimen Label: 4C
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6726329
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6726349
Age: postnatal day 0
Image: S3D Control
Specimen Label: S3D Control
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6726344
Age: postnatal day 4
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-07-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3521628
Stage: TS28
Assay Id: MGI:6726344
Age: postnatal day 4
Image: 2A
Specimen Label: 2A
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-07-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3274228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6726344
Age: postnatal day 4
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2449010
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6726357
Age: embryonic day 14.5
Image: S4E Beta Catenin Chmp1a null
Note: No detectable defect in cortical ventricular surface.
Specimen Label: S4E Beta Catenin Chmp1a null
Detected: true
Specimen Num: 2
Publication
First Author: Sasaki N
Year: 1998
Journal: Genomics
Title: Characterization of gene expression in mouse blastocyst using single-pass sequencing of 3995 clones.
Volume: 49
Issue: 2
Pages: 167-79
Publication
First Author: Azmi I
Year: 2006
Journal: J Cell Biol
Title: Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1.
Volume: 172
Issue: 5
Pages: 705-17
Publication
First Author: Wollert T
Year: 2009
Journal: Nature
Title: Membrane scission by the ESCRT-III complex.
Volume: 458
Issue: 7235
Pages: 172-7
Publication
First Author: Gompers AL
Year: 2017
Journal: Nat Neurosci
Title: Germline Chd8 haploinsufficiency alters brain development in mouse.
Volume: 20
Issue: 8
Pages: 1062-1073
Publication  
First Author: Hermosilla Aguayo V
Year: 2023
Journal: Dev Biol
Title: ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling.
Volume: 503
Pages: 25-42
Publication
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
DO Term