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Search results 1 to 100 out of 540 for Chrnb2

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Hits by Strain

Type Details Score
Gene
1141 | CHRNB2
Type: gene
Organism: human
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Gene
100101688 | chrnb2
Type: gene
Organism: frog, western clawed
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Gene
54239 | Chrnb2
Type: gene
Organism: rat
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Gene
490443 | CHRNB2
Type: gene
Organism: dog, domestic
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Gene
740303 | CHRNB2
Type: gene
Organism: chimpanzee
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Gene
517519 | CHRNB2
Type: gene
Organism: cattle
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Gene
395605 | CHRNB2
Type: gene
Organism: chicken
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Gene
561906 | chrnb2
Type: gene
Organism: zebrafish
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Gene
716830 | CHRNB2
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR032932 | CHRNB2
Type: Family
Description: CHRNB2 is a subunit of the neuronal nicotinic acetylcholine receptor. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions [].Acetylcholine receptors (AChRs) consist of two major subtypes: the metabotropic muscarinic receptors and the ionotropic nicotinic receptors (nAChRs). Both share the property of being activated by the neurotransmitter acetylcholine (ACh), and they are expressed by both neuronal and nonneuronal cells throughout the body []. Multiple subunits have been identified for the nicotinic acetylcholine receptors (nAChRs). Mutations in CHRNB2 are associated with epilepsy [].
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Protein Coding Gene
MGI:87891 | Chrnb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15964197 | -
First Author: Bertrand D
Year: 2005
Journal: Neurobiol Dis
Title: The CHRNB2 mutation I312M is associated with epilepsy and distinct memory deficits.
Volume: 20
Issue: 3
Pages: 799-804
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Publication
22361591 | -
First Author: Bondarenko V
Year: 2012
Journal: Biochim Biophys Acta
Title: NMR structures of the transmembrane domains of the α4β2 nAChR.
Volume: 1818
Issue: 5
Pages: 1261-8
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Publication
19126755 | -
First Author: Albuquerque EX
Year: 2009
Journal: Physiol Rev
Title: Mammalian nicotinic acetylcholine receptors: from structure to function.
Volume: 89
Issue: 1
Pages: 73-120
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Protein
Q8VI08
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: true
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Protein
Q9ERK7
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
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Protein
Q9R1J5
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: true
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Protein
A0A0G2JG64
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: false
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Protein
Q9R0C3
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: true
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Protein
Q9R291
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
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GXD Expression
GXD Expression
   
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189981
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Chrnb2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189981
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Chrnb2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189981
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Chrnb2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189981
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Chrnb2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189981
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Chrnb2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189981
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Chrnb2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189981
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Chrnb2
Detected: true
Specimen Num: 7
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Protein Coding Gene
MGP_CAROLIEiJ_G0025216 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027409 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027418 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027160 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_87891 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027272 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027240 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027381 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026340 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026660 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026159 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7870173 | J:23256
First Author: Picciotto MR
Year: 1995
Journal: Nature
Title: Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain.
Volume: 374
Issue: 6517
Pages: 65-7
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Publication
34242565 | J:325339
First Author: Nguyen C
Year: 2021
Journal: Neuron
Title: Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety.
Volume: 109
Issue: 16
Pages: 2604-2615.e9
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Publication
15738419 | J:96861
First Author: Cohen G
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function.
Volume: 102
Issue: 10
Pages: 3817-21
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Publication
21784105 | J:176976
First Author: Serreau P
Year: 2011
Journal: Behav Brain Res
Title: Beta2-containing neuronal nicotinic receptors as major actors in the flexible choice between conflicting motivations.
Volume: 225
Issue: 1
Pages: 151-9
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Publication
24184117 | J:207700
 
First Author: Liu Q
Year: 2014
Journal: Neuroscience
Title: Genetic deficiency of β2-containing nicotinic receptors attenuates brain injury in ischemic stroke.
Volume: 256
Pages: 170-7
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Publication
18832468 | J:143437
First Author: Avale ME
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion.
Volume: 105
Issue: 41
Pages: 15991-6
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Publication
24554727 | J:234229
First Author: Konsolaki E
Year: 2015
Journal: Cereb Cortex
Title: Premature Aging Phenotype in Mice Lacking High-Affinity Nicotinic Receptors: Region-Specific Changes in Layer V Pyramidal Cell Morphology.
Volume: 25
Issue: 8
Pages: 2138-48
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Publication
23882123 | J:203702
First Author: Coura RS
Year: 2013
Journal: FASEB J
Title: Nonaggressive and adapted social cognition is controlled by the interplay between noradrenergic and nicotinic receptor mechanisms in the prefrontal cortex.
Volume: 27
Issue: 11
Pages: 4343-54
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Publication
26780509 | J:234431
First Author: Naudé J
Year: 2016
Journal: Nat Neurosci
Title: Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking.
Volume: 19
Issue: 3
Pages: 471-8
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Publication
25610381 | J:242254
 
First Author: Nosjean A
Year: 2014
Journal: Front Behav Neurosci
Title: Acute stress in adulthood impoverishes social choices and triggers aggressiveness in preclinical models.
Volume: 8
Pages: 447
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Publication
21810785 | J:198111
First Author: Bourgeois JP
Year: 2012
Journal: Cereb Cortex
Title: Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment.
Volume: 22
Issue: 5
Pages: 1007-15
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Publication
15727510 | J:180875
First Author: Butt CM
Year: 2005
Journal: Behav Neurosci
Title: Modulation of nicotine but not ethanol preference by the mouse Chrna4 A529T polymorphism.
Volume: 119
Issue: 1
Pages: 26-37
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Publication
16752141 | J:135890
First Author: Besson M
Year: 2006
Journal: Psychopharmacology (Berl)
Title: Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome.
Volume: 187
Issue: 2
Pages: 189-99
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Publication
10064590 | J:53601
First Author: Zoli M
Year: 1999
Journal: EMBO J
Title: Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors.
Volume: 18
Issue: 5
Pages: 1235-44
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Publication
18757739 | J:139123
First Author: Sun C
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Retinal waves in mice lacking the beta2 subunit of the nicotinic acetylcholine receptor.
Volume: 105
Issue: 36
Pages: 13638-43
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Publication
32737187 | J:317134
 
First Author: Morozova E
Year: 2020
Journal: eNeuro
Title: Distinct Temporal Structure of Nicotinic ACh Receptor Activation Determines Responses of VTA Neurons to Endogenous ACh and Nicotine.
Volume: 7
Issue: 4
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Publication
25787992 | J:242445
First Author: Xu HP
Year: 2015
Journal: Dev Neurobiol
Title: Spatial pattern of spontaneous retinal waves instructs retinotopic map refinement more than activity frequency.
Volume: 75
Issue: 6
Pages: 621-40
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Publication
11044747 | J:97376
First Author: Caldarone BJ
Year: 2000
Journal: Neuropharmacology
Title: Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain.
Volume: 39
Issue: 13
Pages: 2779-84
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Publication
15215293 | J:97276
First Author: Léna C
Year: 2004
Journal: J Neurosci
Title: Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice.
Volume: 24
Issue: 25
Pages: 5711-8
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Publication
20534523 | J:161388
First Author: Ballesteros-Yáñez I
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Alterations of cortical pyramidal neurons in mice lacking high-affinity nicotinic receptors.
Volume: 107
Issue: 25
Pages: 11567-72
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Publication
16033902 | J:99845
First Author: Mrsic-Flogel TD
Year: 2005
Journal: J Neurosci
Title: Altered map of visual space in the superior colliculus of mice lacking early retinal waves.
Volume: 25
Issue: 29
Pages: 6921-8
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Publication
21689598 | J:175246
First Author: Xu HP
Year: 2011
Journal: Neuron
Title: An instructive role for patterned spontaneous retinal activity in mouse visual map development.
Volume: 70
Issue: 6
Pages: 1115-27
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Publication
15210938 | J:91432
First Author: Mechawar N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb.
Volume: 101
Issue: 26
Pages: 9822-6
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Publication
23986674 | J:290324
 
First Author: Chabout J
Year: 2013
Journal: Front Hum Neurosci
Title: Making choice between competing rewards in uncertain vs. safe social environment: role of neuronal nicotinic receptors of acetylcholine.
Volume: 7
Pages: 468
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Publication
15456819 | J:109772
First Author: Grubb MS
Year: 2004
Journal: J Neurosci
Title: Visual response properties in the dorsal lateral geniculate nucleus of mice lacking the beta2 subunit of the nicotinic acetylcholine receptor.
Volume: 24
Issue: 39
Pages: 8459-69
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Publication
22433585 | J:185456
First Author: Horst NK
Year: 2012
Journal: Behav Brain Res
Title: Impaired auditory discrimination learning following perinatal nicotine exposure or β2 nicotinic acetylcholine receptor subunit deletion.
Volume: 231
Issue: 1
Pages: 170-80
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Publication
14687550 | J:87146
First Author: Grubb MS
Year: 2003
Journal: Neuron
Title: Abnormal functional organization in the dorsal lateral geniculate nucleus of mice lacking the beta 2 subunit of the nicotinic acetylcholine receptor.
Volume: 40
Issue: 6
Pages: 1161-72
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Publication
19077117 | J:151142
First Author: Mineur YS
Year: 2009
Journal: Genes Brain Behav
Title: Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning.
Volume: 8
Issue: 3
Pages: 257-66
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Publication
16965547 | J:112912
First Author: Villégier AS
Year: 2006
Journal: Eur J Neurosci
Title: Irreversible blockade of monoamine oxidases reveals the critical role of 5-HT transmission in locomotor response induced by nicotine in mice.
Volume: 24
Issue: 5
Pages: 1359-65
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Publication
11282258 | J:106489
First Author: Zachariou V
Year: 2001
Journal: Neuropsychopharmacology
Title: Nicotine receptor inactivation decreases sensitivity to cocaine.
Volume: 24
Issue: 5
Pages: 576-89
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Publication
26269630 | J:226024
First Author: Sigalas C
Year: 2015
Journal: J Neurosci
Title: High-Affinity Nicotinic Receptors Modulate Spontaneous Cortical Up States In Vitro.
Volume: 35
Issue: 32
Pages: 11196-208
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Publication
27199738 | J:289575
 
First Author: Konsolaki E
Year: 2016
Journal: Front Aging Neurosci
Title: Early Signs of Pathological Cognitive Aging in Mice Lacking High-Affinity Nicotinic Receptors.
Volume: 8
Pages: 91
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Publication
15536004 | J:102511
First Author: Grubb MS
Year: 2004
Journal: Vision Res
Title: Biochemical and anatomical subdivision of the dorsal lateral geniculate nucleus in normal mice and in mice lacking the beta2 subunit of the nicotinic acetylcholine receptor.
Volume: 44
Issue: 28
Pages: 3365-76
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Publication
36028313 | J:352614
First Author: Zhang HJ
Year: 2023
Journal: J Neurosci
Title: Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by In Vitro Cellular Studies and In Vivo PET Imaging.
Volume: 43
Issue: 1
Pages: 2-13
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Publication
11145999 | J:263495
First Author: Grady SR
Year: 2001
Journal: J Neurochem
Title: Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum.
Volume: 76
Issue: 1
Pages: 258-68
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Publication
15450117 | J:102005
First Author: Dauger S
Year: 2004
Journal: Acta Physiol Scand
Title: Control of breathing in newborn mice lacking the beta-2 nAChR subunit.
Volume: 182
Issue: 2
Pages: 205-12
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Publication
12876201 | J:99880
First Author: Granon S
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Executive and social behaviors under nicotinic receptor regulation.
Volume: 100
Issue: 16
Pages: 9596-601
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Publication
33845128 | J:331137
 
First Author: Dhanasobhon D
Year: 2021
Journal: Neurobiol Dis
Title: Enhanced analgesic cholinergic tone in the spinal cord in a mouse model of neuropathic pain.
Volume: 155
Pages: 105363
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Publication
19020025 | J:142366
First Author: Pons S
Year: 2008
Journal: J Neurosci
Title: Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration.
Volume: 28
Issue: 47
Pages: 12318-27
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Publication
17622669 | J:134917
First Author: Zanardi A
Year: 2007
Journal: FASEB J
Title: Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment.
Volume: 21
Issue: 14
Pages: 4028-37
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Publication
9428762 | J:45151
First Author: Picciotto MR
Year: 1998
Journal: Nature
Title: Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine.
Volume: 391
Issue: 6663
Pages: 173-7
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Publication
37958495 | J:342592
 
First Author: Zammit M
Year: 2023
Journal: Int J Mol Sci
Title: Evaluation of an Image-Derived Input Function for Kinetic Modeling of Nicotinic Acetylcholine Receptor-Binding PET Ligands in Mice.
Volume: 24
Issue: 21
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Publication
11955523 | J:97341
First Author: Shoaib M
Year: 2002
Journal: Neuropharmacology
Title: The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion.
Volume: 42
Issue: 4
Pages: 530-9
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Publication
12736354 | J:123821
First Author: King SL
Year: 2003
Journal: J Neurosci
Title: Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior.
Volume: 23
Issue: 9
Pages: 3837-43
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Publication
15464132 | J:97219
 
First Author: King SL
Year: 2004
Journal: Neuropharmacology
Title: Beta2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration.
Volume: 47 Suppl 1
Pages: 132-9
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Publication
18701068 | J:149877
First Author: Huberman AD
Year: 2008
Journal: Neuron
Title: Architecture and activity-mediated refinement of axonal projections from a mosaic of genetically identified retinal ganglion cells.
Volume: 59
Issue: 3
Pages: 425-38
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Publication
34913435 | J:319846
   
First Author: Tworig JM
Year: 2021
Journal: Elife
Title: Excitatory neurotransmission activates compartmentalized calcium transients in Müller glia without affecting lateral process motility.
Volume: 10
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Publication
19176801 | J:144829
First Author: Liu Q
Year: 2009
Journal: J Neurosci
Title: A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides.
Volume: 29
Issue: 4
Pages: 918-29
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Publication
19874788 | J:157303
First Author: Stafford BK
Year: 2009
Journal: Neuron
Title: Spatial-temporal patterns of retinal waves underlying activity-dependent refinement of retinofugal projections.
Volume: 64
Issue: 2
Pages: 200-12
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Publication
22179110 | J:181567
First Author: Zhang J
Year: 2011
Journal: Nat Neurosci
Title: Visual map development depends on the temporal pattern of binocular activity in mice.
Volume: 15
Issue: 2
Pages: 298-307
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Publication
18171946 | J:131048
First Author: Shah RD
Year: 2008
Journal: J Neurosci
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Year: 2016
Journal: PLoS One
Title: Geniculo-Cortical Projection Diversity Revealed within the Mouse Visual Thalamus.
Volume: 11
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Title: Evidence for an instructive role of retinal activity in retinotopic map refinement in the superior colliculus of the mouse.
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Journal: Eur Neuropsychopharmacol
Title: Hippocampal nAChRs mediate nicotine withdrawal-related learning deficits.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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