|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 523 for Chrnb2

<< First    < Previous  |  Next >    Last >>
0.053s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: CHRNB2 is a subunit of the neuronal nicotinic acetylcholine receptor. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions [].Acetylcholine receptors (AChRs) consist of two major subtypes: the metabotropic muscarinic receptors and the ionotropic nicotinic receptors (nAChRs). Both share the property of being activated by the neurotransmitter acetylcholine (ACh), and they are expressed by both neuronal and nonneuronal cells throughout the body []. Multiple subunits have been identified for the nicotinic acetylcholine receptors (nAChRs). Mutations in CHRNB2 are associated with epilepsy [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Bertrand D
Year: 2005
Journal: Neurobiol Dis
Title: The CHRNB2 mutation I312M is associated with epilepsy and distinct memory deficits.
Volume: 20
Issue: 3
Pages: 799-804
Publication
First Author: Bondarenko V
Year: 2012
Journal: Biochim Biophys Acta
Title: NMR structures of the transmembrane domains of the α4β2 nAChR.
Volume: 1818
Issue: 5
Pages: 1261-8
Publication
First Author: Albuquerque EX
Year: 2009
Journal: Physiol Rev
Title: Mammalian nicotinic acetylcholine receptors: from structure to function.
Volume: 89
Issue: 1
Pages: 73-120
Protein
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 501  
Fragment?: false
GXD Expression    
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189981
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Chrnb2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189981
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Chrnb2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189981
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Chrnb2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189981
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Chrnb2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189981
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Chrnb2
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189981
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Chrnb2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6169803
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189981
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Chrnb2
Detected: true
Specimen Num: 5
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Huberman AD
Year: 2008
Journal: Neuron
Title: Architecture and activity-mediated refinement of axonal projections from a mosaic of genetically identified retinal ganglion cells.
Volume: 59
Issue: 3
Pages: 425-38
Publication
First Author: King SL
Year: 2003
Journal: J Neurosci
Title: Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior.
Volume: 23
Issue: 9
Pages: 3837-43
Publication
First Author: Zhang J
Year: 2011
Journal: Nat Neurosci
Title: Visual map development depends on the temporal pattern of binocular activity in mice.
Volume: 15
Issue: 2
Pages: 298-307
Publication
First Author: Xu HP
Year: 2015
Journal: Dev Neurobiol
Title: Spatial pattern of spontaneous retinal waves instructs retinotopic map refinement more than activity frequency.
Volume: 75
Issue: 6
Pages: 621-40
Publication
First Author: Xu J
Year: 2011
Journal: Mol Psychiatry
Title: Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor.
Volume: 16
Issue: 10
Pages: 1048-61
Publication
First Author: Manfredi I
Year: 2009
Journal: Hum Mol Genet
Title: Expression of mutant beta2 nicotinic receptors during development is crucial for epileptogenesis.
Volume: 18
Issue: 6
Pages: 1075-88
Publication
First Author: Nissen NI
Year: 2018
Journal: PLoS One
Title: Augmenting the antinociceptive effects of nicotinic acetylcholine receptor activity through lynx1 modulation.
Volume: 13
Issue: 7
Pages: e0199643
Publication    
First Author: Tworig JM
Year: 2021
Journal: Elife
Title: Excitatory neurotransmission activates compartmentalized calcium transients in Müller glia without affecting lateral process motility.
Volume: 10
Publication
First Author: Konsolaki E
Year: 2015
Journal: Cereb Cortex
Title: Premature Aging Phenotype in Mice Lacking High-Affinity Nicotinic Receptors: Region-Specific Changes in Layer V Pyramidal Cell Morphology.
Volume: 25
Issue: 8
Pages: 2138-48
Publication
First Author: Nguyen C
Year: 2021
Journal: Neuron
Title: Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety.
Volume: 109
Issue: 16
Pages: 2604-2615.e9
Publication
First Author: Cang J
Year: 2005
Journal: Neuron
Title: Development of precise maps in visual cortex requires patterned spontaneous activity in the retina.
Volume: 48
Issue: 5
Pages: 797-809
Publication
First Author: Shah RD
Year: 2008
Journal: J Neurosci
Title: Retinocollicular synapse maturation and plasticity are regulated by correlated retinal waves.
Volume: 28
Issue: 1
Pages: 292-303
Publication
First Author: Raybuck JD
Year: 2009
Journal: Eur J Neurosci
Title: Nicotine withdrawal-induced deficits in trace fear conditioning in C57BL/6 mice--a role for high-affinity beta2 subunit-containing nicotinic acetylcholine receptors.
Volume: 29
Issue: 2
Pages: 377-87
Publication
First Author: Chandrasekaran AR
Year: 2005
Journal: J Neurosci
Title: Evidence for an instructive role of retinal activity in retinotopic map refinement in the superior colliculus of the mouse.
Volume: 25
Issue: 29
Pages: 6929-38
Publication
First Author: Wang L
Year: 2009
Journal: J Neurosci
Title: Direction-specific disruption of subcortical visual behavior and receptive fields in mice lacking the beta2 subunit of nicotinic acetylcholine receptor.
Volume: 29
Issue: 41
Pages: 12909-18
Publication
First Author: Leiwe MN
Year: 2016
Journal: PLoS One
Title: Geniculo-Cortical Projection Diversity Revealed within the Mouse Visual Thalamus.
Volume: 11
Issue: 1
Pages: e0144846
Publication
First Author: Liu Q
Year: 2009
Journal: J Neurosci
Title: A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides.
Volume: 29
Issue: 4
Pages: 918-29
Publication  
First Author: Konsolaki E
Year: 2016
Journal: Front Aging Neurosci
Title: Early Signs of Pathological Cognitive Aging in Mice Lacking High-Affinity Nicotinic Receptors.
Volume: 8
Pages: 91
Publication
First Author: Sun C
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Retinal waves in mice lacking the beta2 subunit of the nicotinic acetylcholine receptor.
Volume: 105
Issue: 36
Pages: 13638-43
Publication  
First Author: Huang PS
Year: 2011
Journal: Neuroscience
Title: Regulated expression of neuronal SIRT1 and related genes by aging and neuronal β2-containing nicotinic cholinergic receptors.
Volume: 196
Pages: 189-202
Publication
First Author: Muir-Robinson G
Year: 2002
Journal: J Neurosci
Title: Retinogeniculate axons undergo eye-specific segregation in the absence of eye-specific layers.
Volume: 22
Issue: 13
Pages: 5259-64
Publication
First Author: Gochberg-Sarver A
Year: 2012
Journal: Mol Genet Metab
Title: Tnfα, Cox2 and AdipoQ adipokine gene expression levels are modulated in murine adipose tissues by both nicotine and nACh receptors containing the β2 subunit.
Volume: 107
Issue: 3
Pages: 561-70
Publication
First Author: Sottile SY
Year: 2017
Journal: J Neurosci
Title: Presynaptic Neuronal Nicotinic Receptors Differentially Shape Select Inputs to Auditory Thalamus and Are Negatively Impacted by Aging.
Volume: 37
Issue: 47
Pages: 11377-11389
Publication
First Author: Davis JA
Year: 2009
Journal: Eur Neuropsychopharmacol
Title: Hippocampal nAChRs mediate nicotine withdrawal-related learning deficits.
Volume: 19
Issue: 8
Pages: 551-61
Publication
First Author: Chandrasekaran AR
Year: 2007
Journal: J Neurosci
Title: Developmental homeostasis of mouse retinocollicular synapses.
Volume: 27
Issue: 7
Pages: 1746-55
Publication
First Author: Elstrott J
Year: 2008
Journal: Neuron
Title: Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.
Volume: 58
Issue: 4
Pages: 499-506
Publication
First Author: Stafford BK
Year: 2009
Journal: Neuron
Title: Spatial-temporal patterns of retinal waves underlying activity-dependent refinement of retinofugal projections.
Volume: 64
Issue: 2
Pages: 200-12
Publication
First Author: McLaughlin T
Year: 2003
Journal: Neuron
Title: Retinotopic map refinement requires spontaneous retinal waves during a brief critical period of development.
Volume: 40
Issue: 6
Pages: 1147-60
Publication
First Author: Caldarone BJ
Year: 2008
Journal: Neurosci Lett
Title: Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice.
Volume: 439
Issue: 2
Pages: 187-91
Publication
First Author: Picciotto MR
Year: 1995
Journal: Nature
Title: Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain.
Volume: 374
Issue: 6517
Pages: 65-7
Publication
First Author: Zachariou V
Year: 2001
Journal: Neuropsychopharmacology
Title: Nicotine receptor inactivation decreases sensitivity to cocaine.
Volume: 24
Issue: 5
Pages: 576-89
Publication
First Author: Mrsic-Flogel TD
Year: 2005
Journal: J Neurosci
Title: Altered map of visual space in the superior colliculus of mice lacking early retinal waves.
Volume: 25
Issue: 29
Pages: 6921-8
Publication
First Author: Grubb MS
Year: 2004
Journal: J Neurosci
Title: Visual response properties in the dorsal lateral geniculate nucleus of mice lacking the beta2 subunit of the nicotinic acetylcholine receptor.
Volume: 24
Issue: 39
Pages: 8459-69
Publication  
First Author: Nosjean A
Year: 2014
Journal: Front Behav Neurosci
Title: Acute stress in adulthood impoverishes social choices and triggers aggressiveness in preclinical models.
Volume: 8
Pages: 447
Publication
First Author: Xu HP
Year: 2011
Journal: Neuron
Title: An instructive role for patterned spontaneous retinal activity in mouse visual map development.
Volume: 70
Issue: 6
Pages: 1115-27
Publication
First Author: Mechawar N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb.
Volume: 101
Issue: 26
Pages: 9822-6
Publication
First Author: Butt CM
Year: 2005
Journal: Behav Neurosci
Title: Modulation of nicotine but not ethanol preference by the mouse Chrna4 A529T polymorphism.
Volume: 119
Issue: 1
Pages: 26-37
Publication  
First Author: Liu Q
Year: 2014
Journal: Neuroscience
Title: Genetic deficiency of β2-containing nicotinic receptors attenuates brain injury in ischemic stroke.
Volume: 256
Pages: 170-7
Publication
First Author: Zanardi A
Year: 2007
Journal: FASEB J
Title: Loss of high-affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment.
Volume: 21
Issue: 14
Pages: 4028-37
Publication
First Author: Picciotto MR
Year: 1998
Journal: Nature
Title: Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine.
Volume: 391
Issue: 6663
Pages: 173-7
Publication  
First Author: Chabout J
Year: 2013
Journal: Front Hum Neurosci
Title: Making choice between competing rewards in uncertain vs. safe social environment: role of neuronal nicotinic receptors of acetylcholine.
Volume: 7
Pages: 468
Publication  
First Author: Morozova E
Year: 2020
Journal: eNeuro
Title: Distinct Temporal Structure of Nicotinic ACh Receptor Activation Determines Responses of VTA Neurons to Endogenous ACh and Nicotine.
Volume: 7
Issue: 4
Publication
First Author: Shoaib M
Year: 2002
Journal: Neuropharmacology
Title: The role of nicotinic receptor beta-2 subunits in nicotine discrimination and conditioned taste aversion.
Volume: 42
Issue: 4
Pages: 530-9
Publication
First Author: Villégier AS
Year: 2006
Journal: Eur J Neurosci
Title: Irreversible blockade of monoamine oxidases reveals the critical role of 5-HT transmission in locomotor response induced by nicotine in mice.
Volume: 24
Issue: 5
Pages: 1359-65
Publication
First Author: Besson M
Year: 2006
Journal: Psychopharmacology (Berl)
Title: Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome.
Volume: 187
Issue: 2
Pages: 189-99
Publication
First Author: Mineur YS
Year: 2009
Journal: Genes Brain Behav
Title: Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning.
Volume: 8
Issue: 3
Pages: 257-66
Publication
First Author: Granon S
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Executive and social behaviors under nicotinic receptor regulation.
Volume: 100
Issue: 16
Pages: 9596-601
Publication
First Author: Cohen G
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function.
Volume: 102
Issue: 10
Pages: 3817-21
Publication
First Author: Grubb MS
Year: 2003
Journal: Neuron
Title: Abnormal functional organization in the dorsal lateral geniculate nucleus of mice lacking the beta 2 subunit of the nicotinic acetylcholine receptor.
Volume: 40
Issue: 6
Pages: 1161-72
Publication  
First Author: King SL
Year: 2004
Journal: Neuropharmacology
Title: Beta2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration.
Volume: 47 Suppl 1
Pages: 132-9
Publication
First Author: Pons S
Year: 2008
Journal: J Neurosci
Title: Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration.
Volume: 28
Issue: 47
Pages: 12318-27
Publication
First Author: Serreau P
Year: 2011
Journal: Behav Brain Res
Title: Beta2-containing neuronal nicotinic receptors as major actors in the flexible choice between conflicting motivations.
Volume: 225
Issue: 1
Pages: 151-9
Publication
First Author: Naudé J
Year: 2016
Journal: Nat Neurosci
Title: Nicotinic receptors in the ventral tegmental area promote uncertainty-seeking.
Volume: 19
Issue: 3
Pages: 471-8
Publication
First Author: Bourgeois JP
Year: 2012
Journal: Cereb Cortex
Title: Modulation of the mouse prefrontal cortex activation by neuronal nicotinic receptors during novelty exploration but not by exploration of a familiar environment.
Volume: 22
Issue: 5
Pages: 1007-15