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Search results 1 to 97 out of 97 for Cip2a

0.045s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: Cancerous inhibitor of PP2A (CIP2A) functions via protein binding through interactions with many other proteins including MYC, polo like kinase (PLK1) and NIMA protein. It is an inhibitor of PP2A, a tumour suppressor. CIP2A binds to PP2A and inhibits its phosphatase functions resulting in tumorigenic transformation of cells [, ]. CIP2A is overexpressed at a high frequency in a number of tumours and expression levels are independent markers for long-term outcomes in many of these tumours [].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Junttila MR
Year: 2007
Journal: Cell
Title: CIP2A inhibits PP2A in human malignancies.
Volume: 130
Issue: 1
Pages: 51-62
Protein
Organism: Mus musculus/domesticus
Length: 907  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 907  
Fragment?: false
Publication
First Author: De P
Year: 2014
Journal: Oncotarget
Title: Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands.
Volume: 5
Issue: 13
Pages: 4581-602
Publication
First Author: Ventelä S
Year: 2012
Journal: PLoS One
Title: CIP2A promotes proliferation of spermatogonial progenitor cells and spermatogenesis in mice.
Volume: 7
Issue: 3
Pages: e33209
Publication
First Author: Côme C
Year: 2016
Journal: PLoS One
Title: CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection.
Volume: 11
Issue: 4
Pages: e0152996
Publication
First Author: Kerosuo L
Year: 2010
Journal: Differentiation
Title: CIP2A increases self-renewal and is linked to Myc in neural progenitor cells.
Volume: 80
Issue: 1
Pages: 68-77
Publication
First Author: Laine A
Year: 2013
Journal: Cancer Discov
Title: Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.
Volume: 3
Issue: 2
Pages: 182-97
Publication
First Author: Myant K
Year: 2015
Journal: Cell Rep
Title: Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation.
Volume: 12
Issue: 6
Pages: 1019-31
Publication
First Author: Wang H
Year: 2017
Journal: Development
Title: CIP2A acts as a scaffold for CEP192-mediated microtubule organizing center assembly by recruiting Plk1 and aurora A during meiotic maturation.
Volume: 144
Issue: 20
Pages: 3829-3839
Publication  
First Author: Shentu YP
Year: 2019
Journal: Neurobiol Aging
Title: CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits.
Volume: 75
Pages: 198-208
Publication
First Author: Zhou Y
Year: 2020
Journal: FASEB J
Title: Polyphyllin I attenuates cognitive impairments and reduces AD-like pathology through CIP2A-PP2A signaling pathway in 3XTg-AD mice.
Volume: 34
Issue: 12
Pages: 16414-16431
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3294521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3294521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3F
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3H
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3H
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1D
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4818673
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818678
Age: embryonic day 13.0
Specimen Label: 2A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3560828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Note: Expression is in a subset of cells.
Specimen Label: 3D
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3H
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1D
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1B
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Note: Expression is in a subset of cells.
Specimen Label: 3D
Detected: true
Specimen Num: 2
UniProt Feature
Begin: 1
Description: Protein CIP2A
Type: chain
End: 907
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Soo Hoo L
Year: 2002
Journal: Oncogene
Title: Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Volume: 21
Issue: 32
Pages: 5006-15
Publication
First Author: Laine A
Year: 2021
Journal: Cancer Res
Title: CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis.
Volume: 81
Issue: 16
Pages: 4319-4331
Publication
First Author: Zou Z
Year: 2015
Journal: J Cell Biol
Title: mTORC2 promotes cell survival through c-Myc-dependent up-regulation of E2F1.
Volume: 211
Issue: 1
Pages: 105-22
Publication
First Author: Guenebeaud C
Year: 2010
Journal: Mol Cell
Title: The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase.
Volume: 40
Issue: 6
Pages: 863-76
Publication
First Author: Gomes LR
Year: 2017
Journal: Autophagy
Title: Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.
Volume: 13
Issue: 5
Pages: 928-940
Publication
First Author: Khanna A
Year: 2013
Journal: Cancer Res
Title: Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target.
Volume: 73
Issue: 22
Pages: 6548-53
Publication
First Author: Endicott SJ
Year: 2021
Journal: Autophagy
Title: Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy.
Volume: 17
Issue: 3
Pages: 612-625
Publication
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112