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Search results 1 to 98 out of 98 for Cip2a

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Hits by Category

Hits by Strain

Type Details Score
Gene
57650 | CIP2A
Type: gene
Organism: human
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Gene
100216050 | cip2a
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR042510 | CIP2A
Type: Family
Description: Cancerous inhibitor of PP2A (CIP2A) functions via protein binding through interactions with many other proteins including MYC, polo like kinase (PLK1) and NIMA protein. It is an inhibitor of PP2A, a tumour suppressor. CIP2A binds to PP2A and inhibits its phosphatase functions resulting in tumorigenic transformation of cells [, ]. CIP2A is overexpressed at a high frequency in a number of tumours and expression levels are independent markers for long-term outcomes in many of these tumours [].
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Gene
360711 | Cip2a
Type: gene
Organism: rat
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Gene
478554 | CIP2A
Type: gene
Organism: dog, domestic
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Gene
741836 | CIP2A
Type: gene
Organism: chimpanzee
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Gene
538580 | CIP2A
Type: gene
Organism: cattle
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Gene
418410 | CIP2A
Type: gene
Organism: chicken
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Gene
560948 | cip2a
Type: gene
Organism: zebrafish
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Gene
705690 | CIP2A
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2146335 | Cip2a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17632056 | -
First Author: Junttila MR
Year: 2007
Journal: Cell
Title: CIP2A inhibits PP2A in human malignancies.
Volume: 130
Issue: 1
Pages: 51-62
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Protein
Q8BWY9
Organism: Mus musculus/domesticus
Length: 907  
Fragment?: false
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Protein
D3Z7B5
Organism: Mus musculus/domesticus
Length: 907  
Fragment?: false
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Publication
25015035 | -
First Author: De P
Year: 2014
Journal: Oncotarget
Title: Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A (CIP2A): an oncoprotein with many hands.
Volume: 5
Issue: 13
Pages: 4581-602
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Publication
22461891 | J:187134
First Author: Ventelä S
Year: 2012
Journal: PLoS One
Title: CIP2A promotes proliferation of spermatogonial progenitor cells and spermatogenesis in mice.
Volume: 7
Issue: 3
Pages: e33209
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Publication
20447748 | J:161534
First Author: Kerosuo L
Year: 2010
Journal: Differentiation
Title: CIP2A increases self-renewal and is linked to Myc in neural progenitor cells.
Volume: 80
Issue: 1
Pages: 68-77
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Publication
27100879 | J:249206
First Author: Côme C
Year: 2016
Journal: PLoS One
Title: CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection.
Volume: 11
Issue: 4
Pages: e0152996
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Publication
23306062 | J:194350
First Author: Laine A
Year: 2013
Journal: Cancer Discov
Title: Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.
Volume: 3
Issue: 2
Pages: 182-97
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Publication
26235622 | J:232896
First Author: Myant K
Year: 2015
Journal: Cell Rep
Title: Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation.
Volume: 12
Issue: 6
Pages: 1019-31
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Publication
28935709 | J:245932
First Author: Wang H
Year: 2017
Journal: Development
Title: CIP2A acts as a scaffold for CEP192-mediated microtubule organizing center assembly by recruiting Plk1 and aurora A during meiotic maturation.
Volume: 144
Issue: 20
Pages: 3829-3839
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Publication
30594047 | J:276151
 
First Author: Shentu YP
Year: 2019
Journal: Neurobiol Aging
Title: CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits.
Volume: 75
Pages: 198-208
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Publication
33070372 | J:311352
First Author: Zhou Y
Year: 2020
Journal: FASEB J
Title: Polyphyllin I attenuates cognitive impairments and reduces AD-like pathology through CIP2A-PP2A signaling pathway in 3XTg-AD mice.
Volume: 34
Issue: 12
Pages: 16414-16431
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Protein Coding Gene
MGP_CAROLIEiJ_G0020798 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022871 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022838 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2146335 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023285 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022574 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022705 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022681 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021867 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016495 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021697 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3294521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3294521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3H
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3H
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4818673
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818678
Age: embryonic day 13.0
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3560828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Note: Expression is in a subset of cells.
Specimen Label: 3D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Specimen Label: 3H
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4818676
Assay Type: RNA in situ
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672021
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:4818677
Age: embryonic day 13.0
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4818675
Assay Type: Immunohistochemistry
Annotation Date: 2010-08-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4818680
Age: postnatal week 40
Note: Expression is in a subset of cells.
Specimen Label: 3D
Detected: true
Specimen Num: 2
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UniProt Feature
UniProt Feature
Begin: 1
Description: Protein CIP2A
Type: chain
End: 907
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
12118381 | -
First Author: Soo Hoo L
Year: 2002
Journal: Oncogene
Title: Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Volume: 21
Issue: 32
Pages: 5006-15
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Publication
34145035 | J:309417
First Author: Laine A
Year: 2021
Journal: Cancer Res
Title: CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis.
Volume: 81
Issue: 16
Pages: 4319-4331
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Publication
39443726 | J:358925
First Author: Tinsley SL
Year: 2024
Journal: Oncogene
Title: KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development.
Volume: 43
Issue: 50
Pages: 3673-3687
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Publication
26459601 | J:237592
First Author: Zou Z
Year: 2015
Journal: J Cell Biol
Title: mTORC2 promotes cell survival through c-Myc-dependent up-regulation of E2F1.
Volume: 211
Issue: 1
Pages: 105-22
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Publication
21172653 | J:178432
First Author: Guenebeaud C
Year: 2010
Journal: Mol Cell
Title: The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase.
Volume: 40
Issue: 6
Pages: 863-76
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Publication
28410006 | J:309805
First Author: Gomes LR
Year: 2017
Journal: Autophagy
Title: Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.
Volume: 13
Issue: 5
Pages: 928-940
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Publication
24204027 | J:206744
First Author: Khanna A
Year: 2013
Journal: Cancer Res
Title: Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target.
Volume: 73
Issue: 22
Pages: 6548-53
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Publication
32013718 | J:307425
First Author: Endicott SJ
Year: 2021
Journal: Autophagy
Title: Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy.
Volume: 17
Issue: 3
Pages: 612-625
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Publication
15368895 | J:92575
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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