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Search results 1 to 100 out of 174 for Clcn5

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0.5s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Alex P
Year: 2010
Journal: J Immunol
Title: Clcn5 knockout mice exhibit novel immunomodulatory effects and are more susceptible to dextran sulfate sodium-induced colitis.
Volume: 184
Issue: 7
Pages: 3988-96
Publication
First Author: Tanaka K
Year: 1999
Journal: Genomics
Title: Characterization of novel promoter and enhancer elements of the mouse homologue of the Dent disease gene, CLCN5, implicated in X-linked hereditary nephrolithiasis.
Volume: 58
Issue: 3
Pages: 281-92
Publication
First Author: Piwon N
Year: 2000
Journal: Nature
Title: ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease.
Volume: 408
Issue: 6810
Pages: 369-73
Publication
First Author: Hayama A
Year: 2000
Journal: Gene
Title: Isolation and characterization of the human CLC-5 chloride channel gene promoter.
Volume: 261
Issue: 2
Pages: 355-64
Publication
First Author: Günther W
Year: 2003
Journal: Pflugers Arch
Title: The ClC-5 chloride channel knock-out mouse - an animal model for Dent's disease.
Volume: 445
Issue: 4
Pages: 456-62
Publication
First Author: Lin Z
Year: 2011
Journal: J Biol Chem
Title: Chloride channel (Clc)-5 is necessary for exocytic trafficking of Na+/H+ exchanger 3 (NHE3).
Volume: 286
Issue: 26
Pages: 22833-45
Publication
First Author: Gailly P
Year: 2008
Journal: Kidney Int
Title: A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunction.
Volume: 74
Issue: 1
Pages: 52-61
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Novarino G
Year: 2010
Journal: Science
Title: Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis.
Volume: 328
Issue: 5984
Pages: 1398-401
Publication
First Author: Wang SS
Year: 2000
Journal: Hum Mol Genet
Title: Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.
Volume: 9
Issue: 20
Pages: 2937-45
Publication
First Author: Hara-Chikuma M
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Impaired acidification in early endosomes of ClC-5 deficient proximal tubule.
Volume: 329
Issue: 3
Pages: 941-6
Publication
First Author: van den Hove MF
Year: 2006
Journal: Endocrinology
Title: The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland.
Volume: 147
Issue: 3
Pages: 1287-96
Publication
First Author: Cebotaru V
Year: 2005
Journal: Kidney Int
Title: High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease.
Volume: 68
Issue: 2
Pages: 642-52
Publication
First Author: Silva IV
Year: 2003
Journal: J Bone Miner Res
Title: The ClC-5 knockout mouse model of Dent's disease has renal hypercalciuria and increased bone turnover.
Volume: 18
Issue: 4
Pages: 615-23
Publication
First Author: Wang Y
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: ClC-5: role in endocytosis in the proximal tubule.
Volume: 289
Issue: 4
Pages: F850-62
Publication
First Author: Maritzen T
Year: 2006
Journal: Kidney Int
Title: Kidney-specific upregulation of vitamin D3 target genes in ClC-5 KO mice.
Volume: 70
Issue: 1
Pages: 79-87
Publication
First Author: Luyckx VA
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Diet-dependent hypercalciuria in transgenic mice with reduced CLC5 chloride channel expression.
Volume: 96
Issue: 21
Pages: 12174-9
Publication
First Author: Sayer JA
Year: 2004
Journal: Biochim Biophys Acta
Title: Calcium phosphate and calcium oxalate crystal handling is dependent upon CLC-5 expression in mouse collecting duct cells.
Volume: 1689
Issue: 1
Pages: 83-90
GXD Expression      
Probe: MGI:3707818
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:3708916
Age: embryonic day 17.5
Specimen Label: Fetus
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3707818
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3708916
Age: postnatal day 1
Specimen Label: Neonate
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3707818
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3708916
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6437772
Assay Type: RT-PCR
Annotation Date: 2020-07-06
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:6437788
Age: postnatal adult
Specimen Label: O
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6437772
Assay Type: RT-PCR
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6437788
Age: embryonic day 1.0
Specimen Label: 2
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6437772
Assay Type: RT-PCR
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:6437788
Age: embryonic day 2.0
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6437772
Assay Type: RT-PCR
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6437788
Age: embryonic day 2.5
Specimen Label: 8
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6437772
Assay Type: RT-PCR
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360454
Stage: TS04
Assay Id: MGI:6437788
Age: embryonic day 3.0
Specimen Label: M
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6437772
Assay Type: RT-PCR
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:6437788
Age: embryonic day 3.5
Specimen Label: B
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6437772
Assay Type: RT-PCR
Annotation Date: 2020-07-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6437788
Age: embryonic day 0.5
Specimen Label: 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7485849
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7485958
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/+>
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7485849
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7485958
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/->
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7485849
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7485961
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/+>
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7485849
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7485961
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/->
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7485849
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:7485962
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/+>
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7485849
Assay Type: RT-PCR
Annotation Date: 2023-05-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:7485962
Age: postnatal week 8-15
Specimen Label: hnRNP A1<+/->
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2813026
Pattern: Spotted
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2838726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3157126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2828126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3156626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3157026
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2834926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1795226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2775626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1927926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3128126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2837026
Pattern: Spotted
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2832226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2834626
Pattern: Spotted
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2831026
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5299085
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:2801126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5543069
Age: embryonic day 17.5
Image: GUDMAP:14619
Specimen Label: GUDMAP:14619
Specimen Num: 1
Publication  
First Author: Katsura KA
Year: 2014
Journal: Matrix Biol
Title: WDR72 models of structure and function: a stage-specific regulator of enamel mineralization.
Volume: 38
Pages: 48-58
Publication
First Author: Huang L
Year: 2005
Journal: J Biol Chem
Title: Identification and functional characterization of a voltage-gated chloride channel and its novel splice variant in taste bud cells.
Volume: 280
Issue: 43
Pages: 36150-7
Publication
First Author: Rugarli EI
Year: 1995
Journal: Nat Genet
Title: Different chromosomal localization of the Clcn4 gene in Mus spretus and C57BL/6J mice.
Volume: 10
Issue: 4
Pages: 466-71
Publication
First Author: Festa BP
Year: 2019
Journal: Hum Mol Genet
Title: OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease.
Volume: 28
Issue: 12
Pages: 1931-1946
Publication
First Author: Nanami M
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: ENaC inhibition stimulates HCl secretion in the mouse cortical collecting duct. I. Stilbene-sensitive Cl- secretion.
Volume: 309
Issue: 3
Pages: F251-8
Publication
First Author: Barone S
Year: 2023
Journal: Am J Pathol
Title: Identification of an Electrogenic 2Cl(-)/H(+) Exchanger, ClC5, as a Chloride-Secreting Transporter Candidate in Kidney Cyst Epithelium in Tuberous Sclerosis.
Volume: 193
Issue: 2
Pages: 191-200
Publication
First Author: Nielsen R
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.
Volume: 104
Issue: 13
Pages: 5407-12
Publication
First Author: Rickheit G
Year: 2010
Journal: J Biol Chem
Title: Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation.
Volume: 285
Issue: 23
Pages: 17595-603
Publication
First Author: Adler DA
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Evidence of evolutionary up-regulation of the single active X chromosome in mammals based on Clc4 expression levels in Mus spretus and Mus musculus.
Volume: 94
Issue: 17
Pages: 9244-8
Publication
First Author: Wartosch L
Year: 2009
Journal: FASEB J
Title: Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7.
Volume: 23
Issue: 12
Pages: 4056-68
Publication
First Author: Rudloff S
Year: 2021
Journal: Nat Commun
Title: Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress.
Volume: 12
Issue: 1
Pages: 549
Publication
First Author: Pohl M
Year: 2015
Journal: J Am Soc Nephrol
Title: Short-term functional adaptation of aquaporin-1 surface expression in the proximal tubule, a component of glomerulotubular balance.
Volume: 26
Issue: 6
Pages: 1269-78
Publication
First Author: Christensen EI
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.
Volume: 100
Issue: 14
Pages: 8472-7
Publication
First Author: Shevchuk AI
Year: 2012
Journal: J Cell Biol
Title: An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy.
Volume: 197
Issue: 4
Pages: 499-508
Publication
First Author: Steidl C
Year: 2000
Journal: Genomics
Title: Characterization of the human and mouse HEY1, HEY2, and HEYL genes: cloning, mapping, and mutation screening of a new bHLH gene family.
Volume: 66
Issue: 2
Pages: 195-203
Publication
First Author: Newton JM
Year: 1996
Journal: Genomics
Title: Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene.
Volume: 37
Issue: 2
Pages: 219-25
Publication
First Author: Sutter I
Year: 2014
Journal: J Lipid Res
Title: Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate.
Volume: 55
Issue: 8
Pages: 1730-7
Publication
First Author: Reed AA
Year: 2010
Journal: Am J Physiol Renal Physiol
Title: CLC-5 and KIF3B interact to facilitate CLC-5 plasma membrane expression, endocytosis, and microtubular transport: relevance to pathophysiology of Dent's disease.
Volume: 298
Issue: 2
Pages: F365-80
Publication
First Author: Jouret F
Year: 2004
Journal: Kidney Int
Title: Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5.
Volume: 65
Issue: 1
Pages: 198-208
Publication
First Author: Palmer S
Year: 1995
Journal: Nat Genet
Title: A contravention of Ohno's law in mice.
Volume: 10
Issue: 4
Pages: 472-6
Publication
First Author: Montini E
Year: 1998
Journal: Genomics
Title: Identification and characterization of a novel serine-threonine kinase gene from the Xp22 region.
Volume: 51
Issue: 3
Pages: 427-33