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Search results 1 to 100 out of 250 for Cln8

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Ranta S
Year: 1999
Journal: Nat Genet
Title: The neuronal ceroid lipofuscinoses in human EPMR and mnd mutant mice are associated with mutations in CLN8.
Volume: 23
Issue: 2
Pages: 233-6
Publication
First Author: di Ronza A
Year: 2018
Journal: Nat Cell Biol
Title: CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis.
Volume: 20
Issue: 12
Pages: 1370-1377
GXD Expression    
Probe: MGI:4354238
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Scattered
Stage: TS22
Assay Id: MGI:4354964
Age: embryonic day 14.5
Specimen Label: Table S5 - Cln8
Detected: true
Specimen Num: 1
Gene
Type: gene
Organism: human
Publication  
First Author: Lonka L
Year: 2005
Journal: BMC Neurosci
Title: The neuronal ceroid lipofuscinosis Cln8 gene expression is developmentally regulated in mouse brain and up-regulated in the hippocampal kindling model of epilepsy.
Volume: 6
Pages: 27
Publication
First Author: Seigel GM
Year: 2005
Journal: Eye (Lond)
Title: Progression of early postnatal retinal pathology in a mouse model of neuronal ceroid lipofuscinosis.
Volume: 19
Issue: 12
Pages: 1306-12
Publication
First Author: Galizzi G
Year: 2011
Journal: Neurosci Lett
Title: Different early ER-stress responses in the CLN8(mnd) mouse model of neuronal ceroid lipofuscinosis.
Volume: 488
Issue: 3
Pages: 258-62
Publication
First Author: Fujita K
Year: 1998
Journal: Brain Res
Title: Increase of glial fibrillary acidic protein fragments in the spinal cord of motor neuron degeneration mutant mouse.
Volume: 785
Issue: 1
Pages: 31-40
Publication
First Author: Mazurkiewicz JE
Year: 1991
Journal: Neurosci Lett
Title: Ubiquitin deposits are present in spinal motor neurons in all stages of the disease in the motor neuron degeneration (Mnd) mutant of the mouse.
Volume: 128
Issue: 2
Pages: 182-6
Publication
First Author: Porter JC
Year: 1997
Journal: Mol Cell Neurosci
Title: The motor neuron degeneration (mnd) gene acts intrinsically in motor neurons and peripheral fibroblasts.
Volume: 9
Issue: 3
Pages: 185-93
Publication
First Author: Bolivar VJ
Year: 2002
Journal: Brain Res
Title: The development of behavioral abnormalities in the motor neuron degeneration (mnd) mouse.
Volume: 937
Issue: 1-2
Pages: 74-82
Publication
First Author: Messer A
Year: 1995
Journal: Am J Med Genet
Title: Genetics of primary and timing effects in the mnd mouse.
Volume: 57
Issue: 2
Pages: 361-4
Publication
First Author: Boyce S
Year: 1999
Journal: Exp Neurol
Title: Onset and progression of motor deficits in motor neuron degeneration (mnd) mice are unaltered by the glycine/NMDA receptor antagonist L-701,324 or the MAO-B inhibitor R(-)-deprenyl.
Volume: 155
Issue: 1
Pages: 49-58
Publication
First Author: Bennett MJ
Year: 1997
Journal: Neuropediatrics
Title: In-utero and post-delivery supplementation of motor neuron degeneration mutant mice with polyunsaturated fatty acids does not alter the clinical or pathological course.
Volume: 28
Issue: 1
Pages: 82-4
Publication
First Author: Griffin JL
Year: 2002
Journal: Physiol Genomics
Title: Vitamin E deficiency and metabolic deficits in neuronal ceroid lipofuscinosis described by bioinformatics.
Volume: 11
Issue: 3
Pages: 195-203
Publication
First Author: Vance JE
Year: 1997
Journal: Biochim Biophys Acta
Title: Abnormalities in mitochondria-associated membranes and phospholipid biosynthetic enzymes in the mnd/mnd mouse model of neuronal ceroid lipofuscinosis.
Volume: 1344
Issue: 3
Pages: 286-99
Publication
First Author: Messer A
Year: 1986
Journal: J Neurogenet
Title: Autosomal dominance in a late-onset motor neuron disease in the mouse.
Volume: 3
Issue: 6
Pages: 345-55
Publication
First Author: Messer A
Year: 1993
Journal: Neuromuscul Disord
Title: Accumulating autofluorescent material as a marker for early changes in the spinal cord of the Mnd mouse.
Volume: 3
Issue: 2
Pages: 129-34
Publication
First Author: Ghezzi P
Year: 1998
Journal: Eur Cytokine Netw
Title: Tumor necrosis factor is increased in the spinal cord of an animal model of motor neuron degeneration.
Volume: 9
Issue: 2
Pages: 139-44
Publication
First Author: Bronson RT
Year: 1993
Journal: Ann Neurol
Title: Motor neuron degeneration of mice is a model of neuronal ceroid lipofuscinosis (Batten's disease).
Volume: 33
Issue: 4
Pages: 381-5
Publication
First Author: Mennini T
Year: 1999
Journal: Eur J Neurosci
Title: Biochemical and pharmacological evidence of a functional role of AMPA receptors in motor neuron dysfunction in mnd mice.
Volume: 11
Issue: 5
Pages: 1705-10
Publication
First Author: Pardo CA
Year: 1994
Journal: Am J Pathol
Title: Accumulation of the adenosine triphosphate synthase subunit C in the mnd mutant mouse. A model for neuronal ceroid lipofuscinosis.
Volume: 144
Issue: 4
Pages: 829-35
Publication
First Author: Bertamini M
Year: 2002
Journal: Eur J Neurosci
Title: Mitochondrial oxidative metabolism in motor neuron degeneration (mnd) mouse central nervous system.
Volume: 16
Issue: 12
Pages: 2291-6
Publication
First Author: Fujita K
Year: 1998
Journal: Neurochem Res
Title: Alteration of enzymatic activities implicating neuronal degeneration in the spinal cord of the motor neuron degeneration mouse during postnatal development.
Volume: 23
Issue: 4
Pages: 557-62
Publication
First Author: Mennini T
Year: 2004
Journal: Cytokine
Title: Glial activation and TNFR-I upregulation precedes motor dysfunction in the spinal cord of mnd mice.
Volume: 25
Issue: 3
Pages: 127-35
Publication
First Author: Oh C
Year: 1994
Journal: J Neurosci Res
Title: (-)-Deprenyl alters the survival of adult murine facial motoneurons after axotomy: increases in vulnerable C57BL strain but decreases in motor neuron degeneration mutants.
Volume: 38
Issue: 1
Pages: 64-74
Publication
First Author: Mazurkiewicz JE
Year: 1993
Journal: J Neurol Sci
Title: Cytoplasmic inclusions in spinal neurons of the motor neuron degeneration (Mnd) mouse. I. Light microscopic analysis.
Volume: 116
Issue: 1
Pages: 59-66
Publication
First Author: Cook S
Year: 1993
Journal: Mouse Genome
Title: New mutation - motor neuron degeneration - mnd
Volume: 91
Issue: 2
Pages: 313
Publication
First Author: Guarneri R
Year: 2004
Journal: Brain Res
Title: Retinal oxidation, apoptosis and age- and sex-differences in the mnd mutant mouse, a model of neuronal ceroid lipofuscinosis.
Volume: 1014
Issue: 1-2
Pages: 209-20
Publication
First Author: Battaglioli G
Year: 1993
Journal: J Neurochem
Title: Synaptosomal glutamate uptake declines progressively in the spinal cord of a mutant mouse with motor neuron disease.
Volume: 60
Issue: 4
Pages: 1567-9
Publication
First Author: Messer A
Year: 1999
Journal: Mol Genet Metab
Title: An early-onset congenic strain of the motor neuron degeneration (mnd) mouse.
Volume: 66
Issue: 4
Pages: 393-7
Publication
First Author: Mennini T
Year: 2002
Journal: J Neurosci Res
Title: Expression of glutamate receptor subtypes in the spinal cord of control and mnd mice, a model of motor neuron disorder.
Volume: 70
Issue: 4
Pages: 553-60
Publication
First Author: Callahan LM
Year: 1991
Journal: J Neuropathol Exp Neurol
Title: Neurofilament distribution is altered in the Mnd (motor neuron degeneration) mouse.
Volume: 50
Issue: 4
Pages: 491-504
Publication
First Author: Messer A
Year: 1993
Journal: Exp Eye Res
Title: Retinal degeneration in motor neuron degeneration (mnd) mutant mice.
Volume: 57
Issue: 5
Pages: 637-41
Publication
First Author: Chang B
Year: 1994
Journal: Invest Ophthalmol Vis Sci
Title: Retinal degeneration in motor neuron degeneration: a mouse model of ceroid lipofuscinosis.
Volume: 35
Issue: 3
Pages: 1071-6
Publication
First Author: Salpeter EM
Year: 2021
Journal: Ann Transl Med
Title: Retinal degeneration in mice and humans with neuronal ceroid lipofuscinosis type 8.
Volume: 9
Issue: 15
Pages: 1274
Publication
First Author: Plummer J
Year: 1995
Journal: Mol Cell Neurosci
Title: Accelerated and widespread neuronal loss occurs in motor neuron degeneration (mnd) mice expressing a neurofilament-disrupting transgene.
Volume: 6
Issue: 6
Pages: 532-43
Publication
First Author: Holmes FE
Year: 1996
Journal: Neurosci Lett
Title: Superactivation of transglutaminase type 2 without change in enzyme level occurs during progressive neurodegeneration in the mnd mouse mutant.
Volume: 213
Issue: 3
Pages: 185-8
Publication      
First Author: Messer A
Year: 1993
Journal: Personal Communication
Title: It was originally thought that heterozygotes (mnd/+) could be detected at very old ages. However, it has been impossible to repeat these results and, even in 18-month old heterozygotes, no histological pathology is detectable
Publication
First Author: Cooper JD
Year: 1999
Journal: J Neurosci
Title: Apparent loss and hypertrophy of interneurons in a mouse model of neuronal ceroid lipofuscinosis: evidence for partial response to insulin-like growth factor-1 treatment.
Volume: 19
Issue: 7
Pages: 2556-67
Publication
First Author: Bermingham NA
Year: 1996
Journal: Genomics
Title: The mouse lysosomal membrane protein 1 gene as a candidate for the motorneuron degeneration (mnd) locus.
Volume: 32
Issue: 2
Pages: 266-71
Publication
First Author: Messer A
Year: 1992
Journal: Genomics
Title: Mapping of the motor neuron degeneration (Mnd) gene, a mouse model of amyotrophic lateral sclerosis (ALS).
Volume: 13
Issue: 3
Pages: 797-802
Publication
First Author: Bihl F
Year: 2001
Journal: Genes Immun
Title: LPS-hyporesponsiveness of mnd mice is associated with a mutation in Toll-like receptor 4.
Volume: 2
Issue: 1
Pages: 56-9
Publication
First Author: Winter E
Year: 2002
Journal: Trends Biochem Sci
Title: TRAM, LAG1 and CLN8: members of a novel family of lipid-sensing domains?
Volume: 27
Issue: 8
Pages: 381-3
Publication
First Author: Faust JR
Year: 1994
Journal: J Biol Chem
Title: Two related proteolipids and dolichol-linked oligosaccharides accumulate in motor neuron degeneration mice (mnd/mnd), a model for neuronal ceroid lipofuscinosis.
Volume: 269
Issue: 13
Pages: 10150-5
Publication
First Author: Wendt KD
Year: 2005
Journal: Behav Brain Res
Title: Behavioral assessment in mouse models of neuronal ceroid lipofuscinosis using a light-cued T-maze.
Volume: 161
Issue: 2
Pages: 175-82
Publication
First Author: Mennini T
Year: 1998
Journal: J Neurol Sci
Title: Spinal cord GLT-1 glutamate transporter and blood glutamic acid alterations in motor neuron degeneration (Mnd) mice.
Volume: 157
Issue: 1
Pages: 31-6
Publication
First Author: Frey D
Year: 2000
Journal: J Neurosci
Title: Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases.
Volume: 20
Issue: 7
Pages: 2534-42
Publication
First Author: Li J
Year: 1998
Journal: Brain Res Mol Brain Res
Title: Altered gene expression for calpain/calpastatin system in motor neuron degeneration (Mnd) mutant mouse brain and spinal cord.
Volume: 53
Issue: 1-2
Pages: 174-86
Publication
First Author: Passantino R
Year: 2013
Journal: Biochim Biophys Acta
Title: Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis.
Volume: 1833
Issue: 3
Pages: 529-40
Publication  
First Author: Lyly A
Year: 2009
Journal: BMC Cell Biol
Title: Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins.
Volume: 10
Pages: 83
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3848044
Assay Type: Northern blot
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3848058
Age: postnatal week 8-10
Image: 1
Specimen Label: brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3848044
Assay Type: Northern blot
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3848058
Age: postnatal week 8-10
Image: 1
Specimen Label: liver
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3848044
Assay Type: Northern blot
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3848058
Age: postnatal week 8-10
Image: 1
Specimen Label: kidney
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3848044
Assay Type: Northern blot
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:3848058
Age: embryonic day 14.0
Image: 1
Specimen Label: 14 day embryo
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3848044
Assay Type: Northern blot
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3848058
Age: postnatal week 8-10
Image: 1
Specimen Label: thymus
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3848044
Assay Type: Northern blot
Annotation Date: 2009-06-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3848058
Age: postnatal week 8-10
Image: 1
Specimen Label: testis
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3848047
Assay Type: RT-PCR
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3848059
Age: postnatal adult
Image: 1
Specimen Label: heart
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3848047
Assay Type: RT-PCR
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3848059
Age: postnatal adult
Image: 1
Specimen Label: brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3848047
Assay Type: RT-PCR
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3848059
Age: postnatal adult
Image: 1
Specimen Label: lung
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3848047
Assay Type: RT-PCR
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3848059
Age: postnatal adult
Image: 1
Specimen Label: liver
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3848047
Assay Type: RT-PCR
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3848059
Age: postnatal adult
Image: 1
Specimen Label: kidney
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3848047
Assay Type: RT-PCR
Annotation Date: 2009-06-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3848059
Age: postnatal adult
Image: 1
Specimen Label: testis
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3848047
Assay Type: RT-PCR
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3848059
Age: embryonic day 11.0
Image: 1
Specimen Label: 11-day
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:3848047
Assay Type: RT-PCR
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3848059
Age: embryonic day 15.0
Image: 1
Specimen Label: 15-day
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4886353
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945304
Age: embryonic day 11.5
Image: g00798 E11.5
Specimen Label: g00798 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4886353
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945304
Age: embryonic day 15.5
Image: g00798 E15.5
Specimen Label: g00798 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886353
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945304
Age: postnatal day 7
Image: g00798 P7
Specimen Label: g00798 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886353
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945304
Age: embryonic day 11.5
Image: g00798 E11.5
Specimen Label: g00798 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4886353
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945304
Age: postnatal day 7
Image: g00798 P7
Specimen Label: g00798 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3848045
Assay Type: RNA in situ
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3848060
Age: postnatal day 5
Image: 3B
Note: In addition, optical density values of hybridization signals are shown as bars in a diagram.
Specimen Label: 3B
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:3848045
Assay Type: RNA in situ
Annotation Date: 2009-06-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1903728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3848060
Age: postnatal adult
Image: 3D
Note: In addition, optical density values of hybridization signals are shown as bars in a diagram.
Specimen Label: 3D
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4886353
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945304
Age: postnatal day 7
Image: g00798 P7
Specimen Label: g00798 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886353
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945304
Age: embryonic day 15.5
Image: g00798 E15.5
Specimen Label: g00798 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886353
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945304
Age: postnatal day 7
Image: g00798 P7
Specimen Label: g00798 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3848045
Assay Type: RNA in situ
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3848060
Age: postnatal day 5
Image: 3B
Note: In addition, optical density values of hybridization signals are shown as bars in a diagram.
Specimen Label: 3B
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:3848045
Assay Type: RNA in situ
Annotation Date: 2009-06-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3848060
Age: postnatal day 10
Image: 3C
Note: In addition, optical density values of hybridization signals are shown as bars in a diagram.
Specimen Label: 3C
Detected: true
Specimen Num: 8