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Search results 1 to 88 out of 88 for Clptm1

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Hits by Strain

Hits by Category

Type Details Score
Gene
468914 | CLPTM1
Type: gene
Organism: chimpanzee
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Gene
484455 | CLPTM1
Type: gene
Organism: dog, domestic
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Gene
618037 | CLPTM1
Type: gene
Organism: cattle
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Gene
795480 | clptm1
Type: gene
Organism: zebrafish
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Gene
718306 | CLPTM1
Type: gene
Organism: macaque, rhesus
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Gene
1209 | CLPTM1
Type: gene
Organism: human
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Gene
100491880 | clptm1
Type: gene
Organism: frog, western clawed
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Gene
292696 | Clptm1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1927155 | Clptm1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR008429 | CLPTM1
Type: Family
Description: This entry includes cleft lip and palate transmembrane protein 1 (CLPTM1) and cleft lip and palate transmembrane protein 1-like protein (CLPTM1L, also known as CRR9). This entry also includes uncharacterised proteins from fungi and plants. Clefts of the lip and/or palate (CL/P) are some of the most common birth defects. They may be categorised into syndromic or non-syndromic types, with syndromic defects having an underlying chromosomal or teratogenic cause. Around 70% of clefts are non-syndromic and individuals have no typical physical or developmental abnormalities; these clefts generally show polygenetic behaviour and complex inheritance []. Studies have identified regions on chromosomes 19 and 11 which may be involved in non-syndromic cleft lip and palates; this included a novel gene on chromosome 19, cleft lip and palate-associated transmembrane protein 1 (CLPTM1) []. The Poliovirus receptor-related 1 gene (PVRL1), which is located on chromosome 11, has also been shown to associate with non-syndromic cleft lip and palates [, ].Human CLPTM1L is a scramblase that mediates the translocation glucosaminylphosphatidylinositol (alpha-D-GlcN-1-6-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI) []. It protects non-small cell lung cancer tumour cells from genotoxic apoptosis and may contribute to lung cancer risk [, ].
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Publication
9828125 | J:51399
First Author: Yoshiura K
Year: 1998
Journal: Genomics
Title: Characterization of a novel gene disrupted by a balanced chromosomal translocation t(2;19)(q11.2;q13.3) in a family with cleft lip and palate.
Volume: 54
Issue: 2
Pages: 231-40
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Gene
81037 | CLPTM1L
Type: gene
Organism: human
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Publication
29395912 | J:260440
First Author: Ge Y
Year: 2018
Journal: Neuron
Title: Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength.
Volume: 97
Issue: 3
Pages: 596-610.e8
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Protein
Q8BXA5
Organism: Mus musculus/domesticus
Length: 539  
Fragment?: false
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Protein
Q8VBZ3
Organism: Mus musculus/domesticus
Length: 664  
Fragment?: false
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Publication
16122939 | -
First Author: Turhani D
Year: 2005
Journal: J Craniomaxillofac Surg
Title: Mutation analysis of CLPTM 1 and PVRL 1 genes in patients with non-syndromic clefts of lip, alveolus and palate.
Volume: 33
Issue: 5
Pages: 301-6
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Publication
11559849 | -
First Author: Sözen MA
Year: 2001
Journal: Nat Genet
Title: Mutation of PVRL1 is associated with sporadic, non-syndromic cleft lip/palate in northern Venezuela.
Volume: 29
Issue: 2
Pages: 141-2
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Publication
19715471 | -
First Author: Sözen MA
Year: 2009
Journal: Genet Test Mol Biomarkers
Title: Mutation analysis of the PVRL1 gene in caucasians with nonsyndromic cleft lip/palate.
Volume: 13
Issue: 5
Pages: 617-21
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Publication
24366883 | J:208170
First Author: James MA
Year: 2014
Journal: Cancer Res
Title: CRR9/CLPTM1L regulates cell survival signaling and is required for Ras transformation and lung tumorigenesis.
Volume: 74
Issue: 4
Pages: 1116-27
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Publication
22675468 | -
First Author: James MA
Year: 2012
Journal: PLoS One
Title: Functional characterization of CLPTM1L as a lung cancer risk candidate gene in the 5p15.33 locus.
Volume: 7
Issue: 6
Pages: e36116
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Publication
35344438 | -
First Author: Wang Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Genome-wide CRISPR screen reveals CLPTM1L as a lipid scramblase required for efficient glycosylphosphatidylinositol biosynthesis.
Volume: 119
Issue: 14
Pages: e2115083119
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Gene
478630 | CLPTM1L
Type: gene
Organism: dog, domestic
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Gene
461696 | CLPTM1L
Type: gene
Organism: chimpanzee
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Gene
506200 | CLPTM1L
Type: gene
Organism: cattle
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Gene
420973 | CLPTM1L
Type: gene
Organism: chicken
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Gene
436653 | clptm1l
Type: gene
Organism: zebrafish
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Gene
709968 | CLPTM1L
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGP_CAROLIEiJ_G0029301 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031690 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031769 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031491 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1927155 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032235 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030834 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031453 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031608 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031560 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031691 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031596 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032263 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030558 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030934 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021161 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030385 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9218588 | J:42199
First Author: Takeuchi T
Year: 1997
Journal: J Immunol
Title: Transgenic expression of a novel thymic epithelial cell antigen stimulates abberant development of thymocytes.
Volume: 159
Issue: 2
Pages: 726-33
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Publication
7547685 | J:135028
First Author: Takeuchi T
Year: 1995
Journal: Int Immunol
Title: Characterization of a 50 kDa surface membrane protein on thymic stromal cells as an important factor for early T cell development.
Volume: 7
Issue: 4
Pages: 583-90
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Publication
10095063 | J:137983
First Author: Miyazawa H
Year: 1999
Journal: Biochim Biophys Acta
Title: Structure and promoter region of the surface membrane protein HS9 gene expressed on the thymic epithelial cells.
Volume: 1444
Issue: 3
Pages: 407-11
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GXD Expression
GXD Expression
 
Probe: MGI:3807489
Assay Type: Immunohistochemistry
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3807523
Age: postnatal adult
Note: Expression is in lymph node cells in the outer cortex.
Specimen Label: 3E
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3807489
Assay Type: Immunohistochemistry
Annotation Date: 2008-09-24
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3807503
Age: embryonic day 14.0
Note: Expression is in stromal cells.
Specimen Label: 2A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3807489
Assay Type: Immunohistochemistry
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3807503
Age: postnatal week 5
Note: Expression is in the subcapsular area.
Specimen Label: 2C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3807489
Assay Type: Immunohistochemistry
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1930628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3807523
Age: postnatal adult
Note: Expression is in the subcapsular area.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3807489
Assay Type: Immunohistochemistry
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3580928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3807523
Age: postnatal adult
Note: Expression is in white pulp lymphocytes outside the periarteriolar sheath.
Specimen Label: 3C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3807489
Assay Type: Immunohistochemistry
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3807503
Age: postnatal week 5
Note: Expression is in some outer cortex areas.
Specimen Label: 2C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3807489
Assay Type: Immunohistochemistry
Annotation Date: 2008-09-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3586328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3807523
Age: postnatal adult
Specimen Label: 3A
Detected: true
Specimen Num: 1
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Publication
- | J:322048
     
First Author: The Centre for Phenogenomics
Year: 2022
Journal: MGI Direct Data Submission
Title: Direct Data Submission for The Centre for Phenogenomics Alleles.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Clptm1<em1Smoc> | MGI:7289036
Name: cleft lip and palate associated transmembrane protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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