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Search results 1 to 100 out of 104 for Cnga1

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Type Details Score
Gene
1259 | CNGA1
Type: gene
Organism: human
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Gene
739850 | CNGA1
Type: gene
Organism: chimpanzee
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Gene
281700 | CNGA1
Type: gene
Organism: cattle
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Gene
396143 | CNGA1
Type: gene
Organism: chicken
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Gene
704891 | CNGA1
Type: gene
Organism: macaque, rhesus
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Gene
100491997 | cnga1
Type: gene
Organism: frog, western clawed
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Gene
85259 | Cnga1
Type: gene
Organism: rat
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Gene
403891 | CNGA1
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:88436 | Cnga1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR032945 | CNGA1
Type: Family
Description: cGMP-gated cation channel alpha-1 (CNGA1, also known as CNG1) is a alpha subunit of the cyclic nucleotide-gated (CNG) channel. CNG channels control the influx of Ca2+ and Na+ in response to signal-induced changes of cGMP or cAMP levels. They play a key role in olfactory and visual transduction []. Mutations in the CNGA1 gene cause retinitis pigmentosa 49 (RP49), a retinal dystrophy belonging to the group of pigmentary retinopathies [, ].
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Protein
Q5U408
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: false
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Publication
15570217 | -
 
First Author: Zhang Q
Year: 2004
Journal: Mol Vis
Title: Autosomal recessive retinitis pigmentosa in a Pakistani family mapped to CNGA1 with identification of a novel mutation.
Volume: 10
Pages: 884-9
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Publication
36115851 | J:333119
First Author: Kandaswamy S
Year: 2022
Journal: Cell Death Discov
Title: Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model.
Volume: 8
Issue: 1
Pages: 387
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Protein
A0A0G2JG06
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: false
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Publication
7479749 | -
First Author: Dryja TP
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa.
Volume: 92
Issue: 22
Pages: 10177-81
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Publication
10662822 | J:60247
First Author: Gerstner A
Year: 2000
Journal: J Neurosci
Title: Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina.
Volume: 20
Issue: 4
Pages: 1324-32
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Protein
P29974
Organism: Mus musculus/domesticus
Length: 684  
Fragment?: false
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Publication
34418172 | J:325775
First Author: Liu Y
Year: 2021
Journal: FASEB J
Title: Retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGA1.
Volume: 35
Issue: 9
Pages: e21859
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Publication
15634774 | J:95768
First Author: Hüttl S
Year: 2005
Journal: J Neurosci
Title: Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1.
Volume: 25
Issue: 1
Pages: 130-8
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Publication
25319694 | J:217159
First Author: Ramamurthy V
Year: 2014
Journal: J Neurosci
Title: Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor cilia.
Volume: 34
Issue: 42
Pages: 13976-87
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Publication
18303857 | J:133081
First Author: Ding XQ
Year: 2008
Journal: Biochemistry
Title: Functional activity of photoreceptor cyclic nucleotide-gated channels is dependent on the integrity of cholesterol- and sphingolipid-enriched membrane domains.
Volume: 47
Issue: 12
Pages: 3677-87
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Protein Coding Gene
MGP_CAROLIEiJ_G0027287 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029614 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029582 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029530 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029315 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030045 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028724 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029430 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029416 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030079 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028804 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017065 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028279 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7540868 | J:26116
First Author: Karlson KH
Year: 1995
Journal: Biochim Biophys Acta
Title: Cloning of a cGMP-gated cation channel from mouse kidney inner medullary collecting duct.
Volume: 1236
Issue: 1
Pages: 197-200
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Publication
10711714 | J:60737
First Author: Leconte L
Year: 2000
Journal: Invest Ophthalmol Vis Sci
Title: Impairment of rod cGMP-gated channel alpha-subunit expression leads to photoreceptor and bipolar cell degeneration.
Volume: 41
Issue: 3
Pages: 917-26
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Publication
1279673 | J:3370
First Author: Ahmad I
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Mouse cortical collecting duct cells show nonselective cation channel activity and express a gene related to the cGMP-gated rod photoreceptor channel.
Volume: 89
Issue: 21
Pages: 10262-6
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GXD Expression
GXD Expression
     
Probe: MGI:5693590
Assay Type: RT-PCR
Annotation Date: 2015-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:5693745
Age: postnatal
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5693590
Assay Type: RT-PCR
Annotation Date: 2015-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:5693745
Age: postnatal
Specimen Label: Nrl-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7435555
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435590
Age: postnatal month 2
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7435555
Assay Type: RT-PCR
Annotation Date: 2023-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:7435590
Age: postnatal month 2
Specimen Label: Nrl<-/->
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3834429
Assay Type: RNA in situ
Annotation Date: 2009-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3834687
Age: postnatal adult
Image: S7 Nr2e3-/-
Note: Expression was increased in the mutant.
Specimen Label: S7 Nr2e3-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5751135
Assay Type: Immunohistochemistry
Annotation Date: 2016-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5751136
Age: postnatal
Image: 6D
Specimen Label: 6D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3834429
Assay Type: RNA in situ
Annotation Date: 2009-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3834687
Age: postnatal adult
Image: S7 wt
Note: Expression was detected in rods.
Specimen Label: S7 wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5751135
Assay Type: Immunohistochemistry
Annotation Date: 2016-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5751136
Age: postnatal
Image: 6C
Specimen Label: 6C
Detected: true
Specimen Num: 1
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Publication
20890309 | J:168152
First Author: Gupta VK
Year: 2010
Journal: EMBO Rep
Title: Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel.
Volume: 11
Issue: 11
Pages: 861-7
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Publication
11379879 | J:69360
First Author: Bareil C
Year: 2001
Journal: Hum Genet
Title: Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa.
Volume: 108
Issue: 4
Pages: 328-34
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Publication
12649326 | J:82742
First Author: Kelliher KR
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice.
Volume: 100
Issue: 7
Pages: 4299-304
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Publication
9376114 | J:44135
First Author: Folz RJ
Year: 1997
Journal: Am J Respir Cell Mol Biol
Title: Mouse extracellular superoxide dismutase: primary structure, tissue-specific gene expression, chromosomal localization, and lung in situ hybridization.
Volume: 17
Issue: 4
Pages: 393-403
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Publication
9737970 | J:50095
First Author: Spicer AP
Year: 1998
Journal: J Biol Chem
Title: Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes.
Volume: 273
Issue: 39
Pages: 25117-24
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Publication
21593326 | J:173355
First Author: Lewis AS
Year: 2011
Journal: J Neurosci
Title: Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.
Volume: 31
Issue: 20
Pages: 7424-40
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Publication
22192355 | J:179991
First Author: Cisneros-Mejorado A
Year: 2012
Journal: FEBS Lett
Title: cGMP and cyclic nucleotide-gated channels participate in mouse sperm capacitation.
Volume: 586
Issue: 2
Pages: 149-53
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Publication
1372902 | J:2606
First Author: Pittler SJ
Year: 1992
Journal: J Biol Chem
Title: Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel.
Volume: 267
Issue: 9
Pages: 6257-62
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Publication
18654668 | J:140984
First Author: Yang Z
Year: 2008
Journal: J Clin Invest
Title: Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.
Volume: 118
Issue: 8
Pages: 2908-16
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Publication
10725384 | J:61371
First Author: Hong DH
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3).
Volume: 97
Issue: 7
Pages: 3649-54
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Publication
20592197 | J:161846
First Author: Westfall JE
Year: 2010
Journal: J Neurosci
Title: Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1.
Volume: 30
Issue: 26
Pages: 8759-68
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Publication
17698926 | J:129499
First Author: Ferraro TN
Year: 2007
Journal: Physiol Genomics
Title: Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains.
Volume: 31
Issue: 3
Pages: 458-62
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Publication
1315306 | J:2297
First Author: Altherr MR
Year: 1992
Journal: Genomics
Title: Chromosome mapping of the rod photoreceptor cGMP phosphodiesterase beta-subunit gene in mouse and human: tight linkage to the Huntington disease region (4p16.3).
Volume: 12
Issue: 4
Pages: 750-4
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Publication
27328943 | J:239714
First Author: Ronquillo CC
Year: 2016
Journal: FASEB J
Title: Ciliopathy-associated IQCB1/NPHP5 protein is required for mouse photoreceptor outer segment formation.
Volume: 30
Issue: 10
Pages: 3400-3412
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Publication
16868010 | J:114905
First Author: Cheng H
Year: 2006
Journal: Hum Mol Genet
Title: In vivo function of the orphan nuclear receptor NR2E3 in establishing photoreceptor identity during mammalian retinal development.
Volume: 15
Issue: 17
Pages: 2588-602
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Publication
15870395 | J:100830
First Author: Bischof JM
Year: 2005
Journal: Physiol Genomics
Title: Genome-wide analysis of gene transcription in the hypothalamus.
Volume: 22
Issue: 2
Pages: 191-6
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Publication
16267237 | J:102364
First Author: Koike C
Year: 2005
Journal: J Neurosci
Title: Function of atypical protein kinase C lambda in differentiating photoreceptors is required for proper lamination of mouse retina.
Volume: 25
Issue: 44
Pages: 10290-8
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Publication
19805139 | J:153683
First Author: Jia L
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development.
Volume: 106
Issue: 41
Pages: 17534-9
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Publication
33500475 | J:301112
First Author: Maddala R
Year: 2021
Journal: Sci Rep
Title: Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract.
Volume: 11
Issue: 1
Pages: 2203
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Publication
29922981 | J:274446
First Author: Wei W
Year: 2019
Journal: Mol Neurobiol
Title: Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.
Volume: 56
Issue: 3
Pages: 1719-1736
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Publication
15163632 | J:225638
First Author: Yoshida S
Year: 2004
Journal: Hum Mol Genet
Title: Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl.
Volume: 13
Issue: 14
Pages: 1487-503
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Publication
16110338 | J:107820
First Author: Corbo JC
Year: 2005
Journal: PLoS Genet
Title: A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
Volume: 1
Issue: 2
Pages: e11
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Cnga1<em1Smoc> | MGI:7289050
Name: cyclic nucleotide gated channel alpha 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cnga1<m1Mhda> | MGI:7434652
Name: cyclic nucleotide gated channel alpha 1; mutation 1, Martin Hrabe de Angelis
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Genotype
Genotype
Symbol: Cnga1/Cnga1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110377 | retinitis pigmentosa 49
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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