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Search results 1 to 75 out of 75 for Cngb3

0.023s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Kohl S
Year: 2000
Journal: Hum Mol Genet
Title: Mutations in the CNGB3 gene encoding the beta-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3) linked to chromosome 8q21.
Volume: 9
Issue: 14
Pages: 2107-16
Publication
First Author: Xu J
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Early-onset, slow progression of cone photoreceptor dysfunction and degeneration in CNG channel subunit CNGB3 deficiency.
Volume: 52
Issue: 6
Pages: 3557-66
Publication
First Author: Ding XQ
Year: 2009
Journal: Hum Mol Genet
Title: Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism.
Volume: 18
Issue: 24
Pages: 4770-80
Publication
First Author: Hassall MM
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: A Novel Achromatopsia Mouse Model Resulting From a Naturally Occurring Missense Change in Cngb3.
Volume: 59
Issue: 15
Pages: 6102-6110
Publication
First Author: Marangoni D
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Intravitreal Ciliary Neurotrophic Factor Transiently Improves Cone-Mediated Function in a CNGB3-/- Mouse Model of Achromatopsia.
Volume: 56
Issue: 11
Pages: 6810-22
Publication
First Author: Gerstner A
Year: 2000
Journal: J Neurosci
Title: Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina.
Volume: 20
Issue: 4
Pages: 1324-32
Publication
First Author: Thapa A
Year: 2012
Journal: J Biol Chem
Title: Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.
Volume: 287
Issue: 22
Pages: 18018-29
Publication
First Author: Ma H
Year: 2013
Journal: Hum Mol Genet
Title: Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study.
Volume: 22
Issue: 19
Pages: 3906-19
Publication
First Author: Matveev AV
Year: 2008
Journal: J Neurochem
Title: Native cone photoreceptor cyclic nucleotide-gated channel is a heterotetrameric complex comprising both CNGA3 and CNGB3: a study using the cone-dominant retina of Nrl-/- mice.
Volume: 106
Issue: 5
Pages: 2042-55
Publication
First Author: Ding XQ
Year: 2016
Journal: J Biol Chem
Title: The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility.
Volume: 291
Issue: 16
Pages: 8721-34
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3834420
Assay Type: RNA in situ
Annotation Date: 2009-03-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:3834841
Age: postnatal day 14
Image: S1 wt
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3834420
Assay Type: RNA in situ
Annotation Date: 2009-03-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:3834841
Age: postnatal day 14
Image: S1 Nr2e3-/-
Detected: false
Specimen Num: 2
Publication
First Author: Bareil C
Year: 2001
Journal: Hum Genet
Title: Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa.
Volume: 108
Issue: 4
Pages: 328-34
Publication
First Author: Du W
Year: 2015
Journal: Hum Mol Genet
Title: Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3-/-/Nrl-/- mice, an all-cone model of CNGA3 achromatopsia.
Volume: 24
Issue: 13
Pages: 3699-707
Publication
First Author: Ma H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration.
Volume: 111
Issue: 9
Pages: 3602-7
Publication
First Author: Yang F
Year: 2016
Journal: FASEB J
Title: Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration.
Volume: 30
Issue: 12
Pages: 4313-4325
Publication
First Author: Hüttl S
Year: 2005
Journal: J Neurosci
Title: Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1.
Volume: 25
Issue: 1
Pages: 130-8
Publication
First Author: Ma H
Year: 2017
Journal: FASEB J
Title: Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration.
Volume: 31
Issue: 8
Pages: 3425-3438
Publication
First Author: Cisneros-Mejorado A
Year: 2012
Journal: FEBS Lett
Title: cGMP and cyclic nucleotide-gated channels participate in mouse sperm capacitation.
Volume: 586
Issue: 2
Pages: 149-53
Publication
First Author: Fujieda H
Year: 2009
Journal: J Neurochem
Title: Retinoic acid receptor-related orphan receptor alpha regulates a subset of cone genes during mouse retinal development.
Volume: 108
Issue: 1
Pages: 91-101
Publication
First Author: Corbo JC
Year: 2005
Journal: PLoS Genet
Title: A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.
Volume: 1
Issue: 2
Pages: e11
Publication  
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: cyclic nucleotide gated channel beta 3; targeted mutation 1, Deltagen
Allele Type: Targeted
Attribute String: Null/knockout
Publication categories: ProxyCollection
Allele
Name: cyclic nucleotide gated channel beta 3; cone photoreceptor function loss 10
Allele Type: Spontaneous
Attribute String: Not Specified
Publication categories: ProxyCollection
Genotype
Symbol: Cngb3/Cngb3
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
DO Term
Genotype
Symbol: Cngb3/Cngb3
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
HT Experiment
Series Id: GSE40982
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Protein Domain
Type: Family
Description: Cyclic nucleotide-gated cation channel beta-3 (CNGB3, also known as CNG6) is a beta subunit of the cyclic nucleotide-gated (CNG) channel. CNG channels control the influx of Ca2+ and Na+ in response to signal-induced changes of cGMP or cAMP levels. They play a key role in olfactory and visual transduction []. Mutations in the CNGB3 gene have been linked to achromatopsia (rod monochromacy, total colour blindness) [].
Publication
First Author: Yang F
Year: 2020
Journal: FASEB J
Title: Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency.
Volume: 34
Issue: 5
Pages: 6335-6350
Publication  
First Author: Ma H
Year: 2019
Journal: eNeuro
Title: Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency.
Volume: 6
Issue: 3
Publication
First Author: Ma H
Year: 2015
Journal: J Biol Chem
Title: cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice.
Volume: 290
Issue: 34
Pages: 20880-92
Protein
Organism: Mus musculus
Length: 694  
Fragment?: false