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Search results 1 to 100 out of 1017 for Col1a2

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: He L
Year: 2017
Journal: J Clin Invest
Title: Preexisting endothelial cells mediate cardiac neovascularization after injury.
Volume: 127
Issue: 8
Pages: 2968-2981
Publication
First Author: Tian X
Year: 2020
Journal: EMBO J
Title: Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.
Volume: 39
Issue: 4
Pages: e102675
Publication
First Author: Hu B
Year: 2012
Journal: Cell
Title: Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling.
Volume: 149
Issue: 6
Pages: 1207-20
Allele
Name: transgene insertion 7, Christopher P Denton
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
GXD Expression  
Probe: MGI:1400800
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2622022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3825688
Age: embryonic day 14.5
Image: Additional file 4 Col1a2
Detected: true
Specimen Num: 1
Publication
First Author: Marongiu M
Year: 2016
Journal: Dev Biol
Title: Novel action of FOXL2 as mediator of Col1a2 gene autoregulation.
Volume: 416
Issue: 1
Pages: 200-211
Publication
First Author: Daley E
Year: 2010
Journal: J Bone Miner Res
Title: Variable bone fragility associated with an Amish COL1A2 variant and a knock-in mouse model.
Volume: 25
Issue: 2
Pages: 247-61
Publication  
First Author: Tang CM
Year: 2017
Journal: Sci Rep
Title: CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts.
Volume: 7
Pages: 40342
Publication      
First Author: McBride DJ
Year: 2007
Journal: MGI Direct Data Submission
Title: A knock-in mutation of Col1a2
Publication
First Author: Carleton SM
Year: 2008
Journal: Bone
Title: Role of genetic background in determining phenotypic severity throughout postnatal development and at peak bone mass in Col1a2 deficient mice (oim).
Volume: 42
Issue: 4
Pages: 681-94
Allele
Name: collagen, type I, alpha 2; endonuclease-mediated mutation 1, Bin Zhou
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication
First Author: Liu S
Year: 2013
Journal: J Invest Dermatol
Title: Integrin β1 is required for dermal homeostasis.
Volume: 133
Issue: 4
Pages: 899-906
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: congenic, mutant strain, transgenic
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Chakraborty D
Year: 2017
Journal: Nat Commun
Title: Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis.
Volume: 8
Issue: 1
Pages: 1130
Publication
First Author: Riopel MM
Year: 2013
Journal: Lab Invest
Title: β1 integrin-extracellular matrix interactions are essential for maintaining exocrine pancreas architecture and function.
Volume: 93
Issue: 1
Pages: 31-40
Publication
First Author: Zigrino P
Year: 2016
Journal: J Invest Dermatol
Title: Fibroblast-Derived MMP-14 Regulates Collagen Homeostasis in Adult Skin.
Volume: 136
Issue: 8
Pages: 1575-83
Genotype
Symbol: Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
Publication  
First Author: Parapuram SK
Year: 2015
Journal: Matrix Biol
Title: Loss of PTEN expression by mouse fibroblasts results in lung fibrosis through a CCN2-dependent mechanism.
Volume: 43
Pages: 35-41
Publication
First Author: Duan J
Year: 2013
Journal: PLoS One
Title: Rib fractures and death from deletion of osteoblast βcatenin in adult mice is rescued by corticosteroids.
Volume: 8
Issue: 2
Pages: e55757
Publication
First Author: Ijaz T
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Deletion of NF-κB/RelA in Angiotensin II-Sensitive Mesenchymal Cells Blocks Aortic Vascular Inflammation and Abdominal Aortic Aneurysm Formation.
Volume: 37
Issue: 10
Pages: 1881-1890
Publication
First Author: Denton CP
Year: 2009
Journal: J Invest Dermatol
Title: Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing.
Volume: 129
Issue: 1
Pages: 194-204
Publication
First Author: Kapoor M
Year: 2008
Journal: J Clin Invest
Title: GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism.
Volume: 118
Issue: 10
Pages: 3279-90
Publication
First Author: Li Y
Year: 2017
Journal: Circulation
Title: Cardiac Fibroblast-Specific Activating Transcription Factor 3 Protects Against Heart Failure by Suppressing MAP2K3-p38 Signaling.
Volume: 135
Issue: 21
Pages: 2041-2057
Publication  
First Author: Chen H
Year: 2016
Journal: Nat Commun
Title: Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis.
Volume: 7
Pages: 12564
Publication
First Author: Blumbach K
Year: 2010
Journal: J Cell Sci
Title: Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGFβ1 levels and RhoA activity.
Volume: 123
Issue: Pt 22
Pages: 3872-83
Publication
First Author: Penke LR
Year: 2018
Journal: J Clin Invest
Title: FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis.
Volume: 128
Issue: 6
Pages: 2389-2405
Genotype
Symbol: Col1a2/Col1a2<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Shi Y
Year: 2020
Journal: J Pathol
Title: Genetic or pharmacologic blockade of enhancer of zeste homolog 2 inhibits the progression of peritoneal fibrosis.
Volume: 250
Issue: 1
Pages: 79-94
Strain
Attribute String: targeted mutation, transgenic, mutant stock
Publication
First Author: Lagares D
Year: 2017
Journal: Nat Med
Title: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.
Volume: 23
Issue: 12
Pages: 1405-1415
Publication  
First Author: Eguchi A
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: GRK5 is a regulator of fibroblast activation and cardiac fibrosis.
Volume: 118
Issue: 5
Publication
First Author: Wermuth PJ
Year: 2018
Journal: PLoS One
Title: Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib).
Volume: 13
Issue: 5
Pages: e0196559
Publication
First Author: Sonnylal S
Year: 2007
Journal: Arthritis Rheum
Title: Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.
Volume: 56
Issue: 1
Pages: 334-44
Publication
First Author: Woodall MC
Year: 2016
Journal: Circ Res
Title: Cardiac Fibroblast GRK2 Deletion Enhances Contractility and Remodeling Following Ischemia/Reperfusion Injury.
Volume: 119
Issue: 10
Pages: 1116-1127
Publication
First Author: Hutchenreuther J
Year: 2015
Journal: J Invest Dermatol
Title: CCN2 Expression by Tumor Stroma Is Required for Melanoma Metastasis.
Volume: 135
Issue: 11
Pages: 2805-2813
Publication  
First Author: Ruhland MK
Year: 2016
Journal: Nat Commun
Title: Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Volume: 7
Pages: 11762
Publication
First Author: Liu S
Year: 2010
Journal: J Cell Sci
Title: Expression of integrin beta1 by fibroblasts is required for tissue repair in vivo.
Volume: 123
Issue: Pt 21
Pages: 3674-82
Publication
First Author: Hu B
Year: 2015
Journal: Am J Pathol
Title: Mesenchymal deficiency of Notch1 attenuates bleomycin-induced pulmonary fibrosis.
Volume: 185
Issue: 11
Pages: 3066-75
Publication
First Author: Hu B
Year: 2015
Journal: Am J Respir Cell Mol Biol
Title: Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis.
Volume: 52
Issue: 4
Pages: 418-28
Publication
First Author: Hu B
Year: 2012
Journal: Am J Pathol
Title: Mesenchymal-specific deletion of C/EBPβ suppresses pulmonary fibrosis.
Volume: 180
Issue: 6
Pages: 2257-67
Publication
First Author: Liu S
Year: 2011
Journal: Arthritis Rheum
Title: CCN2 is required for bleomycin-induced skin fibrosis in mice.
Volume: 63
Issue: 1
Pages: 239-46
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ccn2/Ccn2 Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: 129S2/SvPas * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tgfbr2/Tgfbr2 Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Meng X
Year: 2018
Journal: Cancer Lett
Title: Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis.
Volume: 418
Pages: 109-118
Publication
First Author: Liu T
Year: 2015
Journal: PLoS One
Title: Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis.
Volume: 10
Issue: 11
Pages: e0142547
Publication
First Author: Duan W
Year: 2011
Journal: J Immunol
Title: Inducible CD4+LAP+Foxp3- regulatory T cells suppress allergic inflammation.
Volume: 187
Issue: 12
Pages: 6499-507
Publication
First Author: Liu S
Year: 2009
Journal: Am J Pathol
Title: Rac1 expression by fibroblasts is required for tissue repair in vivo.
Volume: 174
Issue: 5
Pages: 1847-56
Publication
First Author: Parapuram SK
Year: 2011
Journal: J Invest Dermatol
Title: Loss of PTEN expression by dermal fibroblasts causes skin fibrosis.
Volume: 131
Issue: 10
Pages: 1996-2003
Genotype
Symbol: Tert/Tert Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Bageghni SA
Year: 2018
Journal: FASEB J
Title: Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism.
Volume: 32
Issue: 9
Pages: 4941-4954
Publication  
First Author: Gao R
Year: 2021
Journal: J Clin Invest
Title: Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis.
Volume: 131
Issue: 1
Publication
First Author: Ubil E
Year: 2014
Journal: Nature
Title: Mesenchymal-endothelial transition contributes to cardiac neovascularization.
Volume: 514
Issue: 7524
Pages: 585-90
Publication
First Author: Zimmermann AS
Year: 2014
Journal: PLoS One
Title: Epidermal or dermal specific knockout of PHD-2 enhances wound healing and minimizes ischemic injury.
Volume: 9
Issue: 4
Pages: e93373
Strain
Attribute String: transgenic, targeted mutation, mutant strain
Publication
First Author: Zheng B
Year: 2002
Journal: Am J Pathol
Title: Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis.
Volume: 160
Issue: 5
Pages: 1609-17
Publication
First Author: Ijaz T
Year: 2016
Journal: BMC Dev Biol
Title: Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles.
Volume: 16
Issue: 1
Pages: 32
Publication
First Author: Wohlfahrt T
Year: 2019
Journal: Nature
Title: PU.1 controls fibroblast polarization and tissue fibrosis.
Volume: 566
Issue: 7744
Pages: 344-349
Publication
First Author: Lim WW
Year: 2020
Journal: PLoS One
Title: Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice.
Volume: 15
Issue: 1
Pages: e0227505
Publication
First Author: Kim E
Year: 2020
Journal: Nature
Title: Creation of bladder assembloids mimicking tissue regeneration and cancer.
Volume: 588
Issue: 7839
Pages: 664-669
Publication
First Author: Hamanaka RB
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis.
Volume: 58
Issue: 5
Pages: 585-593
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col1a2-cre/ERT,-ALPP)7Cpd/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Col1a2-cre/ERT,-ALPP)7Cpd
Zygosity: cn
Has Mutant Allele: true
Publication    
First Author: Kim S
Year: 2019
Journal: Elife
Title: Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer.
Volume: 8
Publication  
First Author: Bhattacharyya S
Year: 2016
Journal: Nat Commun
Title: Tenascin-C drives persistence of organ fibrosis.
Volume: 7
Pages: 11703
Publication
First Author: Tan J
Year: 2017
Journal: J Immunol
Title: Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12.
Volume: 198
Issue: 6
Pages: 2269-2285
Publication  
First Author: Helfinger V
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors.
Volume: 118
Issue: 11
Publication
First Author: Pillai ICL
Year: 2017
Journal: Cell Stem Cell
Title: Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification.
Volume: 20
Issue: 2
Pages: 218-232.e5
Publication
First Author: Cho C
Year: 2020
Journal: Oncogene
Title: Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis.
Volume: 39
Issue: 38
Pages: 6129-6137
Publication
First Author: Martinez-Ferrer M
Year: 2010
Journal: Am J Pathol
Title: Dermal transforming growth factor-beta responsiveness mediates wound contraction and epithelial closure.
Volume: 176
Issue: 1
Pages: 98-107
Publication
First Author: Jackson RS 2nd
Year: 2012
Journal: Neoplasia
Title: Sabutoclax, a Mcl-1 antagonist, inhibits tumorigenesis in transgenic mouse and human xenograft models of prostate cancer.
Volume: 14
Issue: 7
Pages: 656-65
Publication
First Author: Liu S
Year: 2014
Journal: Arthritis Rheumatol
Title: Skin progenitor cells contribute to bleomycin-induced skin fibrosis.
Volume: 66
Issue: 3
Pages: 707-13
Publication
First Author: Parapuram SK
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Integrin β1 is necessary for the maintenance of corneal structural integrity.
Volume: 52
Issue: 11
Pages: 7799-806
Publication
First Author: Pallangyo CK
Year: 2015
Journal: J Exp Med
Title: IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
Volume: 212
Issue: 13
Pages: 2253-66
Publication  
First Author: Hutchenreuther J
Year: 2018
Journal: Matrix Biol
Title: Activation of cancer-associated fibroblasts is required for tumor neovascularization in a murine model of melanoma.
Volume: 74
Pages: 52-61
Publication
First Author: Guzy RD
Year: 2017
Journal: J Biol Chem
Title: Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling.
Volume: 292
Issue: 25
Pages: 10364-10378
Publication
First Author: Schafer S
Year: 2017
Journal: Nature
Title: IL-11 is a crucial determinant of cardiovascular fibrosis.
Volume: 552
Issue: 7683
Pages: 110-115
Publication
First Author: Lim J
Year: 2020
Journal: Commun Biol
Title: Primary cilia control cell alignment and patterning in bone development via ceramide-PKCζ-β-catenin signaling.
Volume: 3
Issue: 1
Pages: 45
Publication    
First Author: Sun X
Year: 2020
Journal: Elife
Title: Coordinated hedgehog signaling induces new hair follicles in adult skin.
Volume: 9
Publication
First Author: Tombor LS
Year: 2021
Journal: Nat Commun
Title: Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.
Volume: 12
Issue: 1
Pages: 681
Publication
First Author: Cai CL
Year: 2008
Journal: Nature
Title: A myocardial lineage derives from Tbx18 epicardial cells.
Volume: 454
Issue: 7200
Pages: 104-8
Publication
First Author: Wang L
Year: 2020
Journal: Nat Commun
Title: Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk.
Volume: 11
Issue: 1
Pages: 282
Publication
First Author: Kitamura H
Year: 2011
Journal: J Clin Invest
Title: Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.
Volume: 121
Issue: 7
Pages: 2863-75
Publication
First Author: Dorrier CE
Year: 2021
Journal: Nat Neurosci
Title: CNS fibroblasts form a fibrotic scar in response to immune cell infiltration.
Volume: 24
Issue: 2
Pages: 234-244
Publication
First Author: Feinberg TY
Year: 2018
Journal: Dev Cell
Title: Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs.
Volume: 47
Issue: 2
Pages: 145-160.e6
Publication
First Author: Xie T
Year: 2016
Journal: J Clin Invest
Title: Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis.
Volume: 126
Issue: 8
Pages: 3063-79
Publication
First Author: Sun C
Year: 2017
Journal: Development
Title: PDGFRα controls the balance of stromal and adipogenic cells during adipose tissue organogenesis.
Volume: 144
Issue: 1
Pages: 83-94
Publication    
First Author: Bageghni SA
Year: 2019
Journal: JCI Insight
Title: Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction.
Volume: 5
Publication
First Author: Seldin L
Year: 2020
Journal: Dev Cell
Title: DNA Damage Promotes Epithelial Hyperplasia and Fate Mis-specification via Fibroblast Inflammasome Activation.
Volume: 55
Issue: 5
Pages: 558-573.e6
Publication  
First Author: Gerling M
Year: 2016
Journal: Nat Commun
Title: Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth.
Volume: 7
Pages: 12321
Publication
First Author: Ittmann M
Year: 2013
Journal: Cancer Res
Title: Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.
Volume: 73
Issue: 9
Pages: 2718-36
Publication
First Author: Habermehl D
Year: 2011
Journal: Mol Endocrinol
Title: Glucocorticoid activity during lung maturation is essential in mesenchymal and less in alveolar epithelial cells.
Volume: 25
Issue: 8
Pages: 1280-8
Publication
First Author: Hiebert P
Year: 2018
Journal: Dev Cell
Title: Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome.
Volume: 46
Issue: 2
Pages: 145-161.e10
Publication
First Author: Kisseleva T
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis.
Volume: 109
Issue: 24
Pages: 9448-53