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Search results 1 to 100 out of 3456 for Col2a1

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Type Details Score
Gene
key_979882 | Col2a1
Type: gene
Organism: Not Specified
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Gene
1280 | COL2A1
Type: gene
Organism: human
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Gene
395069 | COL2A1
Type: gene
Organism: chicken
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Gene
704851 | COL2A1
Type: gene
Organism: macaque, rhesus
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Gene
394828 | col2a1
Type: gene
Organism: frog, western clawed
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Gene
407142 | COL2A1
Type: gene
Organism: cattle
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Gene
key_31319 | COL2A1
Type: gene
Organism: rabbit, European
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Gene
25412 | Col2a1
Type: gene
Organism: rat
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Gene
403826 | COL2A1
Type: gene
Organism: dog, domestic
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Gene
451860 | COL2A1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:88452 | Col2a1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:7618257
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7618281
Age: embryonic day 18.5
Image: 1C Col2a1
Specimen Label: 1C Col2a1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3615925
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7545192
Age: embryonic day 17.5
Image: 5C Col2a1 WT
Specimen Label: 5C Col2a1 WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3615927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7545192
Age: postnatal newborn
Image: 5D Col2a1 Gli1-/-
Specimen Label: 5D Col2a1 Gli1-/-
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:7618257
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7618281
Age: embryonic day 18.5
Image: 2G Col2a1 WT
Specimen Label: 2G Col2a1 WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567625
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:7545192
Age: embryonic day 17.5
Image: 5C Col2a1 Gli1-/-
Note: Ectopic expression in perichondrium.
Specimen Label: 5C Col2a1 Gli1-/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3615925
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7545192
Age: embryonic day 17.5
Image: 2B Col2a1 Ihh+/-
Specimen Label: 2B Col2a1 Ihh+/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3615925
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7545192
Age: embryonic day 17.5
Image: 5C Col2a1 Gli1-/-
Specimen Label: 5C Col2a1 Gli1-/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3615927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7545192
Age: postnatal newborn
Image: 5D Col2a1 WT
Specimen Label: 5D Col2a1 WT
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3615927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7545192
Age: postnatal newborn
Image: 5D Col2a1 Gli2-/-
Specimen Label: 5D Col2a1 Gli2-/-
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3615927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7545192
Age: postnatal newborn
Image: 5D Col2a1 Gli1-/-;Gli2-/-
Specimen Label: 5D Col2a1 Gli1-/-;Gli2-/-
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:7618299
Assay Type: RNA in situ
Annotation Date: 2024-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1774222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7618305
Age: embryonic day 14.5
Image: 4D Col2a1 MAML1+/+
Specimen Label: 4D Col2a1 MAML1+/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7618299
Assay Type: RNA in situ
Annotation Date: 2024-04-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1774222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7618305
Age: embryonic day 14.5
Image: 4D Col2a1 MAML1-/-
Note: Zone of expression extended compared to wild type.
Specimen Label: 4D Col2a1 MAML1-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5446226
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262920
Pattern: Widespread
Stage: TS20
Assay Id: MGI:5446475
Age: embryonic day 12.5
Image: 2 Col2a1 12.5 wt
Note: Expression marks cartilaginous condensations. Expression throughout cartilaginous anlagen.
Specimen Label: 2 Col2a1 12.5 wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5446226
Assay Type: RNA in situ
Annotation Date: 2012-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262920
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5446475
Age: embryonic day 12.5
Image: 2 Col2a1 12.5 spdh/spdh
Note: Size, shape and number of cartilaginous condensations is abnormal compared with wild type.
Specimen Label: 2 Col2a1 12.5 spdh/spdh
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7618257
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7618281
Age: embryonic day 18.5
Image: 2G Col2a1 Gsk3a-/-;Gsk3b+/-
Note: Expression in proximal tibia decreased compared to wild type.
Specimen Label: 2G Col2a1 Gsk3a-/-;Gsk3b+/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7545189
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567627
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7545192
Age: postnatal newborn
Image: 5D Col2a1 Gli1-/-;Gli2-/-
Note: Ectopic expression in perichondrium.
Specimen Label: 5D Col2a1 Gli1-/-;Gli2-/-
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:15970
Assay Type: RNA in situ
Annotation Date: 2006-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3687130
Age: embryonic day 12.5
Note: Expression was weak in the most distal precartilaginous condensations of hindlimb buds but was high throughout the more proximal precartilaginous condensations of hindlimb buds.
Specimen Label: 4C Col2a1
Detected: true
Specimen Num: 3
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Publication
9264261 | J:54915
First Author: Zhao Q
Year: 1997
Journal: Dev Dyn
Title: Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis.
Volume: 209
Issue: 4
Pages: 377-86
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Publication
22028304 | J:187141
First Author: Esapa CT
Year: 2012
Journal: J Bone Miner Res
Title: A mouse model for spondyloepiphyseal dysplasia congenita with secondary osteoarthritis due to a Col2a1 mutation.
Volume: 27
Issue: 2
Pages: 413-28
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Publication
14614991 | J:87774
First Author: Fernandes RJ
Year: 2003
Journal: Matrix Biol
Title: Protein consequences of the Col2a1 C-propeptide mutation in the chondrodysplastic Dmm mouse.
Volume: 22
Issue: 5
Pages: 449-53
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Publication
12968670 | J:85735
First Author: Donahue LR
Year: 2003
Journal: J Bone Miner Res
Title: A missense mutation in the mouse Col2a1 gene causes spondyloepiphyseal dysplasia congenita, hearing loss, and retinoschisis.
Volume: 18
Issue: 9
Pages: 1612-21
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Publication
19014360 | J:306544
First Author: Hyde G
Year: 2008
Journal: J Anat
Title: Col2a1 lineage tracing reveals that the meniscus of the knee joint has a complex cellular origin.
Volume: 213
Issue: 5
Pages: 531-8
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Publication
15476249 | J:134147
First Author: Sahlman J
Year: 2004
Journal: Arthritis Rheum
Title: A human COL2A1 gene with an Arg519Cys mutation causes osteochondrodysplasia in transgenic mice.
Volume: 50
Issue: 10
Pages: 3153-60
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Publication
24168833 | J:294744
First Author: Yang RC
Year: 2014
Journal: J Formos Med Assoc
Title: A mutation of the Col2a1 gene (G1170S) alters the transgenic murine phenotype and cartilage matrix homeostasis.
Volume: 113
Issue: 11
Pages: 803-12
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Publication
24475193 | J:212712
First Author: Liang G
Year: 2014
Journal: PLoS One
Title: Endoplasmic reticulum stress-unfolding protein response-apoptosis cascade causes chondrodysplasia in a col2a1 p.Gly1170Ser mutated mouse model.
Volume: 9
Issue: 1
Pages: e86894
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Publication
22248926 | J:184499
First Author: Lewis R
Year: 2012
Journal: Matrix Biol
Title: Disruption of the developmentally-regulated Col2a1 pre-mRNA alternative splicing switch in a transgenic knock-in mouse model.
Volume: 31
Issue: 3
Pages: 214-26
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GXD Expression
GXD Expression
     
Probe: MGI:4354240
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:4354864
Age: embryonic day 14.5
Specimen Label: Table S5 - Col2a1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4354240
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:4354864
Age: embryonic day 14.5
Note: Expression is present in the lower, but not the upper, cortical plate.
Specimen Label: Table S5 - Col2a1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7545152
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3594419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7545241
Age: embryonic day 11.5
Specimen Label: 1C Col2a1 (upper)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7545152
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3594419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7545241
Age: embryonic day 11.5
Specimen Label: 1C Col2a1 (lower)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7310472
Assay Type: RNA in situ
Annotation Date: 2022-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7310479
Age: embryonic day 15.5
Note: Expression patterns not markedly affected compared with wild type.
Specimen Label: 1d -/- Col2a1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7310472
Assay Type: RNA in situ
Annotation Date: 2022-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7310479
Age: embryonic day 15.5
Specimen Label: 1d +/+ Col2a1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4354240
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354864
Age: embryonic day 14.5
Specimen Label: Table S5 - Col2a1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7356571
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-20
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3762028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7356579
Age: postnatal month 12
Note: Type II collagen degraded at the surface layer.
Specimen Label: 2c COL2A1 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7356571
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3762028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7356579
Age: postnatal month 12
Note: Loss of type II collagen protected from surface to deep layer of articular surface.
Specimen Label: 2c COL2A1 MINK1-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7310472
Assay Type: RNA in situ
Annotation Date: 2022-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3802823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7310479
Age: embryonic day 15.5
Note: Expression patterns not markedly affected compared with wild type.
Specimen Label: 1d -/- Col2a1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7310472
Assay Type: RNA in situ
Annotation Date: 2022-07-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3802823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7310479
Age: embryonic day 15.5
Specimen Label: 1d +/+ Col2a1
Detected: true
Specimen Num: 2
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Publication
10620515 | J:60148
 
First Author: Yuan CM
Year: 2000
Journal: Biochem J
Title: Lack of a phenotype in transgenic mice aberrantly expressing COL2A1 mRNA because of highly selective post-transcriptional down-regulation.
Volume: 345 Pt 2
Pages: 377-84
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Publication
9915573 | J:51968
First Author: Rani PU
Year: 1999
Journal: Dev Dyn
Title: Restoration of normal bone development by human homologue of collagen type II (COL2A1) gene in Col2a1 null mice.
Volume: 214
Issue: 1
Pages: 26-33
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Publication
10100048 | J:54161
First Author: Maddox BK
Year: 1998
Journal: J Craniofac Genet Dev Biol
Title: Craniofacial and otic capsule abnormalities in a transgenic mouse strain with a Col2a1 mutation.
Volume: 18
Issue: 4
Pages: 195-201
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Publication
- | J:187363
     
First Author: Curtain MM
Year: 2012
Journal: MGI Direct Data Submission
Title: A New Point Mutation in Col2a1 Causes a Shortened Nose and Cleft Palate
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Publication
12917109 | J:87136
First Author: Barbieri O
Year: 2003
Journal: Am J Physiol Cell Physiol
Title: Depletion of cartilage collagen fibrils in mice carrying a dominant negative Col2a1 transgene affects chondrocyte differentiation.
Volume: 285
Issue: 6
Pages: C1504-12
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Publication
26545783 | J:260538
First Author: Kimura M
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Endoplasmic reticulum stress-mediated apoptosis contributes to a skeletal dysplasia resembling platyspondylic lethal skeletal dysplasia, Torrance type, in a novel Col2a1 mutant mouse line.
Volume: 468
Issue: 1-2
Pages: 86-91
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Publication
9614106 | J:48126
First Author: Zhou G
Year: 1998
Journal: J Biol Chem
Title: Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo.
Volume: 273
Issue: 24
Pages: 14989-97
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Publication
21538020 | J:171906
First Author: Furuichi T
Year: 2011
Journal: Mamm Genome
Title: ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type.
Volume: 22
Issue: 5-6
Pages: 318-28
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Publication
24735995 | J:215404
 
First Author: Hering TM
Year: 2014
Journal: Matrix Biol
Title: Changes in type II procollagen isoform expression during chondrogenesis by disruption of an alternative 5' splice site within Col2a1 exon 2.
Volume: 36
Pages: 51-63
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GXD Expression
GXD Expression
   
Probe: MGI:6170132
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190018
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Col2a1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6170132
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190018
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Col2a1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6170132
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190018
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Col2a1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6170132
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190018
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Col2a1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6170132
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190018
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Col2a1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6170132
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190018
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Col2a1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6170132
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190018
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Col2a1
Detected: true
Specimen Num: 7
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Publication
9061443 | J:39102
 
First Author: Rintala M
Year: 1997
Journal: J Anat
Title: Abnormal craniofacial growth and early mandibular osteoarthritis in mice harbouring a mutant type II collagen transgene.
Volume: 190 ( Pt 2)
Pages: 201-8
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Publication
9171829 | J:41294
First Author: Bell DM
Year: 1997
Journal: Nat Genet
Title: SOX9 directly regulates the type-II collagen gene.
Volume: 16
Issue: 2
Pages: 174-8
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Publication
8349798 | J:14164
First Author: Helminen HJ
Year: 1993
Journal: J Clin Invest
Title: An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice have osteoarthritic changes in joints.
Volume: 92
Issue: 2
Pages: 582-95
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GXD Expression
GXD Expression
     
Probe: MGI:3027395
Assay Type: RT-PCR
Annotation Date: 2004-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1913726
Stage: TS26
Assay Id: MGI:3027398
Age: embryonic day 19.0
Specimen Label: COL2A1 +/+
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:3027395
Assay Type: RT-PCR
Annotation Date: 2004-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1913726
Stage: TS26
Assay Id: MGI:3027398
Age: embryonic day 19.0
Specimen Label: COL2A1 -/+
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
     
Probe: MGI:3027395
Assay Type: RT-PCR
Annotation Date: 2004-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1913726
Stage: TS26
Assay Id: MGI:3027398
Age: embryonic day 19.0
Specimen Label: COL2A1 -/-
Detected: true
Specimen Num: 3
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Publication
12359167 | J:307985
First Author: Arita M
Year: 2002
Journal: Osteoarthritis Cartilage
Title: Skeletal abnormalities and ultrastructural changes of cartilage in transgenic mice expressing a collagen II gene (COL2A1) with a Cys for Arg-alpha1-519 substitution.
Volume: 10
Issue: 10
Pages: 808-15
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Publication
26058470 | J:309481
First Author: Park NR
Year: 2016
Journal: J Cell Physiol
Title: Core Binding Factor β Plays a Critical Role During Chondrocyte Differentiation.
Volume: 231
Issue: 1
Pages: 162-71
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Publication
22547066 | J:187536
First Author: Yamashita S
Year: 2012
Journal: J Biol Chem
Title: L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity.
Volume: 287
Issue: 26
Pages: 22206-15
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Publication
24862038 | J:310847
First Author: Chen H
Year: 2014
Journal: J Bone Miner Res
Title: Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation.
Volume: 29
Issue: 12
Pages: 2653-65
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Publication
23555635 | J:199887
First Author: Tomita N
Year: 2013
Journal: PLoS One
Title: Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth.
Volume: 8
Issue: 3
Pages: e59226
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Publication
28167493 | J:241785
First Author: Whitaker AT
Year: 2017
Journal: Biol Open
Title: Smad4 regulates growth plate matrix production and chondrocyte polarity.
Volume: 6
Issue: 3
Pages: 358-364
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Publication
1618904 | J:1279
First Author: Metsäranta M
Year: 1992
Journal: J Cell Biol
Title: Chondrodysplasia in transgenic mice harboring a 15-amino acid deletion in the triple helical domain of pro alpha 1(II) collagen chain.
Volume: 118
Issue: 1
Pages: 203-12
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Publication
8872705 | J:35591
First Author: Rintala M
Year: 1996
Journal: J Craniofac Genet Dev Biol
Title: Abnormalities in secondary cartilages in four lines of transgenic mice harboring two different types of mutations in the cartilage-specific type II collagen gene.
Volume: 16
Issue: 3
Pages: 148-55
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Publication
7994081 | J:19890
First Author: Hiltunen A
Year: 1994
Journal: Dev Dyn
Title: Retarded chondrogenesis in transgenic mice with a type II collagen defect results in fracture healing abnormalities.
Volume: 200
Issue: 4
Pages: 340-9
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Publication
11273670 | J:68440
First Author: Ihanamäki T
Year: 2001
Journal: Exp Eye Res
Title: Age-dependent changes in the expression of matrix components in the mouse eye.
Volume: 72
Issue: 4
Pages: 423-31
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Publication
12525971 | J:80671
First Author: Ihanamäki T
Year: 2002
Journal: Curr Eye Res
Title: Ultrastructural characterization of developmental and degenerative vitreo-retinal changes in the eyes of transgenic mice with a deletion mutation in type II collagen gene.
Volume: 24
Issue: 6
Pages: 439-50
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Publication
- | J:148829
     
First Author: Esapa C
Year: 2009
Journal: MGI Direct Data Submission
Title: Lpk, longpockets, is an ENU induced mutation and results in a short-limbed phenotype: Record for "Lpk"
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Publication
1881905 | J:31511
First Author: Vandenberg P
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia.
Volume: 88
Issue: 17
Pages: 7640-4
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Publication
25600960 | J:231358
First Author: Cameron TL
Year: 2015
Journal: Osteoarthritis Cartilage
Title: Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization.
Volume: 23
Issue: 4
Pages: 661-70
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Publication
1492704 | J:3718
First Author: Imam-Ghali M
Year: 1992
Journal: Anim Genet
Title: Sheep gene mapping: synteny between COL2A1 and the LDHB-PEPB-TPI-GAPD-LALBA-IGF1 group.
Volume: 23
Issue: 6
Pages: 529-32
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Publication
29287114 | J:256718
First Author: Shimbo M
Year: 2017
Journal: PLoS One
Title: Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2.
Volume: 12
Issue: 12
Pages: e0190333
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Publication
37159303 | J:344106
First Author: Ding W
Year: 2023
Journal: FASEB J
Title: Hu'po Anshen decoction promotes fracture healing in mice with traumatic brain injury through BMP2-COX2-ATF4 signaling pathway.
Volume: 37
Issue: 6
Pages: e22952
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Publication
17519362 | J:127222
First Author: Govoni KE
Year: 2007
Journal: Physiol Genomics
Title: Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice.
Volume: 30
Issue: 3
Pages: 354-62
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Publication
12510713 | J:81856
First Author: Ihanamäki T
Year: 2002
Journal: Eur J Ophthalmol
Title: Expression of Sox9 and type IIA procollagen during ocular development and aging in transgenic Del1 mice with a mutation in the type II collagen gene.
Volume: 12
Issue: 6
Pages: 450-8
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Publication
15562585 | J:95068
First Author: Savontaus M
Year: 2004
Journal: Orthod Craniofac Res
Title: Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene.
Volume: 7
Issue: 4
Pages: 216-26
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Publication
9426396 | J:44842
First Author: Savontaus M
Year: 1997
Journal: Lab Invest
Title: Mutation in type II collagen gene disturbs spinal development and gene expression patterns in transgenic Del1 mice.
Volume: 77
Issue: 6
Pages: 591-600
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Publication
15531369 | J:95024
First Author: Baffi MO
Year: 2004
Journal: Dev Biol
Title: Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones.
Volume: 276
Issue: 1
Pages: 124-42
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Publication
8952549 | J:37148
First Author: Savontaus M
Year: 1996
Journal: Am J Pathol
Title: Retarded skeletal development in transgenic mice with a type II collagen mutation.
Volume: 149
Issue: 6
Pages: 2169-82
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Publication
22492985 | J:197791
First Author: Masago Y
Year: 2012
Journal: J Cell Sci
Title: The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation.
Volume: 125
Issue: Pt 5
Pages: 1118-28
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Publication
7590256 | J:30041
First Author: Li SW
Year: 1995
Journal: Genes Dev
Title: Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone.
Volume: 9
Issue: 22
Pages: 2821-30
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Publication
25541700 | J:225386
First Author: Cionni M
Year: 2014
Journal: PLoS One
Title: The mouse MC13 mutant is a novel ENU mutation in collagen type II, alpha 1.
Volume: 9
Issue: 12
Pages: e116104
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Publication
8948452 | J:26245
 
First Author: Ala-Kokko L
Year: 1995
Journal: Biochem J
Title: Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1).
Volume: 308 ( Pt 3)
Pages: 923-9
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Publication
21246657 | J:167831
First Author: Moffatt P
Year: 2011
Journal: Dev Dyn
Title: Hyaluronan production by means of Has2 gene expression in chondrocytes is essential for long bone development.
Volume: 240
Issue: 2
Pages: 404-12
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Publication
15509771 | J:94393
First Author: Karreth F
Year: 2004
Journal: Development
Title: The AP1 transcription factor Fra2 is required for efficient cartilage development.
Volume: 131
Issue: 22
Pages: 5717-25
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Publication
18025304 | J:135374
First Author: Patra D
Year: 2007
Journal: J Cell Biol
Title: Site-1 protease is essential for endochondral bone formation in mice.
Volume: 179
Issue: 4
Pages: 687-700
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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