Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
COMM10 is a member of the COMMD family defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Phan KP |
Year: |
2023 |
Journal: |
J Dev Biol |
Title: |
COMMD10 Is Essential for Neural Plate Development during Embryogenesis. |
Volume: |
11 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cohen K |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver. |
Volume: |
37 |
Issue: |
7 |
Pages: |
110026 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
202
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
197
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
165
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
113
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
150
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
187
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
190
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
202
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Burstein E |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
COMMD proteins, a novel family of structural and functional homologs of MURR1. |
Volume: |
280 |
Issue: |
23 |
Pages: |
22222-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ben Shlomo S |
Year: |
2019 |
Journal: |
iScience |
Title: |
COMMD10-Guided Phagolysosomal Maturation Promotes Clearance of Staphylococcus aureus in Macrophages. |
Volume: |
14 |
|
Pages: |
147-163 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouhadeb O |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
Impaired COMMD10-Mediated Regulation of Ly6Chi Monocyte-Driven Inflammation Disrupts Gut Barrier Function. |
Volume: |
9 |
|
Pages: |
2623 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Berquam-Vrieze KE |
Year: |
2011 |
Journal: |
Blood |
Title: |
Cell of origin strongly influences genetic selection in a mouse model of T-ALL. |
Volume: |
118 |
Issue: |
17 |
Pages: |
4646-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heger K |
Year: |
2015 |
Journal: |
Eur J Immunol |
Title: |
A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors. |
Volume: |
45 |
Issue: |
6 |
Pages: |
1614-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liberatore RA |
Year: |
2017 |
Journal: |
J Virol |
Title: |
Tetherin Inhibits Cell-Free Virus Dissemination and Retards Murine Leukemia Virus Pathogenesis. |
Volume: |
91 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
de Boer J |
Year: |
2003 |
Journal: |
Eur J Immunol |
Title: |
Transgenic mice with hematopoietic and lymphoid specific expression of Cre. |
Volume: |
33 |
Issue: |
2 |
Pages: |
314-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Menzel U |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Modulation of the murine CD8 gene complex following the targeted integration of human CD2-locus control region sequences. |
Volume: |
187 |
Issue: |
7 |
Pages: |
3712-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakagawa MM |
Year: |
2018 |
Journal: |
Front Cell Dev Biol |
Title: |
Constitutive Activation of NF-κB Pathway in Hematopoietic Stem Cells Causes Loss of Quiescence and Deregulated Transcription Factor Networks. |
Volume: |
6 |
|
Pages: |
143 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kur IM |
Year: |
2020 |
Journal: |
PLoS Biol |
Title: |
Neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo. |
Volume: |
18 |
Issue: |
3 |
Pages: |
e3000643 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nern C |
Year: |
2009 |
Journal: |
J Neurosci |
Title: |
Fusion of hematopoietic cells with Purkinje neurons does not lead to stable heterokaryon formation under noninvasive conditions. |
Volume: |
29 |
Issue: |
12 |
Pages: |
3799-807 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ridder K |
Year: |
2014 |
Journal: |
PLoS Biol |
Title: |
Extracellular vesicle-mediated transfer of genetic information between the hematopoietic system and the brain in response to inflammation. |
Volume: |
12 |
Issue: |
6 |
Pages: |
e1001874 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chamson-Reig A |
Year: |
2010 |
Journal: |
Diabetologia |
Title: |
Lineage tracing and resulting phenotype of haemopoietic-derived cells in the pancreas during beta cell regeneration. |
Volume: |
53 |
Issue: |
10 |
Pages: |
2188-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Siegemund S |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells. |
Volume: |
10 |
Issue: |
4 |
Pages: |
e0124661 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiu Y |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid Leukemia. |
Volume: |
22 |
Issue: |
2 |
Pages: |
350-358 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suga H |
Year: |
2014 |
Journal: |
Stem Cells |
Title: |
Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing. |
Volume: |
32 |
Issue: |
5 |
Pages: |
1347-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yildirim E |
Year: |
2013 |
Journal: |
Cell |
Title: |
Xist RNA is a potent suppressor of hematologic cancer in mice. |
Volume: |
152 |
Issue: |
4 |
Pages: |
727-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Daniel JM |
Year: |
2014 |
Journal: |
Cardiovasc Res |
Title: |
Inhibition of miR-92a improves re-endothelialization and prevents neointima formation following vascular injury. |
Volume: |
103 |
Issue: |
4 |
Pages: |
564-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tiedt R |
Year: |
2008 |
Journal: |
Blood |
Title: |
Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice. |
Volume: |
111 |
Issue: |
8 |
Pages: |
3931-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jani PK |
Year: |
2023 |
Journal: |
PLoS Biol |
Title: |
The miR-221/222 cluster regulates hematopoietic stem cell quiescence and multipotency by suppressing both Fos/AP-1/IEG pathway activation and stress-like differentiation to granulocytes. |
Volume: |
21 |
Issue: |
11 |
Pages: |
e3002015 |
|
•
•
•
•
•
|
Publication |
First Author: |
Joseph C |
Year: |
2013 |
Journal: |
Cell Stem Cell |
Title: |
Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies. |
Volume: |
13 |
Issue: |
5 |
Pages: |
520-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ogilvy S |
Year: |
1999 |
Journal: |
Blood |
Title: |
Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment. |
Volume: |
94 |
Issue: |
6 |
Pages: |
1855-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wittorf KJ |
Year: |
2022 |
Journal: |
Exp Hematol |
Title: |
Ubiquitin E3 ligase FBXO21 regulates cytokine-mediated signaling pathways, but is dispensable for steady-state hematopoiesis. |
Volume: |
114 |
|
Pages: |
33-42.e3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang MY |
Year: |
2013 |
Journal: |
Cell Rep |
Title: |
Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116. |
Volume: |
3 |
Issue: |
5 |
Pages: |
1457-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wirnsberger G |
Year: |
2014 |
Journal: |
Nat Genet |
Title: |
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense. |
Volume: |
46 |
Issue: |
9 |
Pages: |
1028-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang H |
Year: |
2018 |
Journal: |
Cell Res |
Title: |
Loss of YTHDF2-mediated m6A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration. |
Volume: |
28 |
Issue: |
10 |
Pages: |
1035-1038 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang C |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells. |
Volume: |
42 |
Issue: |
2 |
Pages: |
112105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jimenez MT |
Year: |
2022 |
Journal: |
J Exp Med |
Title: |
The miR-181 family regulates colonic inflammation through its activity in the intestinal epithelium. |
Volume: |
219 |
Issue: |
12 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Herrera-Merchan A |
Year: |
2012 |
Journal: |
Nat Commun |
Title: |
Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease. |
Volume: |
3 |
|
Pages: |
623 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang D |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins. |
Volume: |
288 |
Issue: |
7 |
Pages: |
4594-601 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wong R |
Year: |
2020 |
Journal: |
PLoS One |
Title: |
ZBTB38 is dispensable for antibody responses. |
Volume: |
15 |
Issue: |
9 |
Pages: |
e0235183 |
|
•
•
•
•
•
|
Publication |
First Author: |
Valerio DG |
Year: |
2017 |
Journal: |
Blood |
Title: |
Histone acetyltransferase activity of MOF is required for adult but not early fetal hematopoiesis in mice. |
Volume: |
129 |
Issue: |
1 |
Pages: |
48-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Y |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Regulation of the terminal maturation of iNKT cells by mediator complex subunit 23. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3875 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zwicky P |
Year: |
2021 |
Journal: |
Sci Immunol |
Title: |
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation. |
Volume: |
6 |
Issue: |
64 |
Pages: |
eabg9012 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abramowitz LK |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
Chronically Elevated O-GlcNAcylation Limits Nitric Oxide Production and Deregulates Specific Pro-Inflammatory Cytokines. |
Volume: |
13 |
|
Pages: |
802336 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abramowitz LK |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Blocked O-GlcNAc cycling disrupts mouse hematopoeitic stem cell maintenance and early T cell development. |
Volume: |
9 |
Issue: |
1 |
Pages: |
12569 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gotoh K |
Year: |
2020 |
Journal: |
iScience |
Title: |
Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45(-) TER119(-)Erythroid and Lymphoid Progenitors. |
Volume: |
23 |
Issue: |
11 |
Pages: |
101654 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizuguchi S |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
Mitochondrial Reactive Oxygen Species Are Essential for the Development of Psoriatic Inflammation. |
Volume: |
12 |
|
Pages: |
714897 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu SJ |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
SNARE protein SEC22B regulates early embryonic development. |
Volume: |
9 |
Issue: |
1 |
Pages: |
11434 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tawaratsumida K |
Year: |
2022 |
Journal: |
Sci Adv |
Title: |
A phospho-tyrosine-based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity. |
Volume: |
8 |
Issue: |
27 |
Pages: |
eabq0084 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paris J |
Year: |
2019 |
Journal: |
Cell Stem Cell |
Title: |
Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia. |
Volume: |
25 |
Issue: |
1 |
Pages: |
137-148.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao Y |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m(6)A modification-mediated RNA stability control. |
Volume: |
42 |
Issue: |
10 |
Pages: |
113163 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jimbo K |
Year: |
2022 |
Journal: |
Leukemia |
Title: |
Immunoglobulin superfamily member 8 maintains myeloid leukemia stem cells through inhibition of β-catenin degradation. |
Volume: |
36 |
Issue: |
6 |
Pages: |
1550-1562 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tran TM |
Year: |
2022 |
Journal: |
Leukemia |
Title: |
The RNA-binding protein IGF2BP3 is critical for MLL-AF4-mediated leukemogenesis. |
Volume: |
36 |
Issue: |
1 |
Pages: |
68-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Young C |
Year: |
2022 |
Journal: |
Biol Open |
Title: |
Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis. |
Volume: |
11 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Moritsch S |
Year: |
2022 |
Journal: |
Oncoimmunology |
Title: |
Tyk2 is a tumor suppressor in colorectal cancer. |
Volume: |
11 |
Issue: |
1 |
Pages: |
2127271 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen C |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
HIRA, a DiGeorge Syndrome Candidate Gene, Confers Proper Chromatin Accessibility on HSCs and Supports All Stages of Hematopoiesis. |
Volume: |
30 |
Issue: |
7 |
Pages: |
2136-2149.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sahoo M |
Year: |
2018 |
Journal: |
Oncotarget |
Title: |
Hematopoietic stem cell specific V-ATPase controls breast cancer progression and metastasis via cytotoxic T cells. |
Volume: |
9 |
Issue: |
69 |
Pages: |
33215-33231 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sklyarova T |
Year: |
2015 |
Journal: |
Eur J Immunol |
Title: |
Hematopoietic plakophilin-3 regulates acute tissue-specific and systemic inflammation in mice. |
Volume: |
45 |
Issue: |
10 |
Pages: |
2898-910 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao Y |
Year: |
2020 |
Journal: |
Immunity |
Title: |
m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development. |
Volume: |
52 |
Issue: |
6 |
Pages: |
1007-1021.e8 |
|
•
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•
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Journal: |
J Immunol |
Title: |
Zfp318 regulates IgD expression by abrogating transcription termination within the Ighm/Ighd locus. |
Volume: |
193 |
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5 |
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2546-53 |
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First Author: |
Szappanos D |
Year: |
2018 |
Journal: |
PLoS Pathog |
Title: |
The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. |
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14 |
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11 |
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e1007397 |
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J Exp Med |
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The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. |
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2020 |
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Nat Microbiol |
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LY6E impairs coronavirus fusion and confers immune control of viral disease. |
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2018 |
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J Clin Invest |
Title: |
PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signature. |
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128 |
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Year: |
2019 |
Journal: |
J Immunol |
Title: |
IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis. |
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203 |
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4 |
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888-898 |
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First Author: |
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Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Chromatin organizer SATB1 controls the cell identity of CD4(+) CD8(+) double-positive thymocytes by regulating the activity of super-enhancers. |
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13 |
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1 |
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5554 |
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Year: |
2019 |
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Cell Rep |
Title: |
Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses. |
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26 |
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Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Efficient genome-wide first-generation phenotypic screening system in mice using the piggyBac transposon. |
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116 |
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37 |
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PLoS One |
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