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Search results 1 to 100 out of 2205 for Comp

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Li C
Year: 2020
Journal: Nat Commun
Title: Mutations in COMP cause familial carpal tunnel syndrome.
Volume: 11
Issue: 1
Pages: 3642
Publication
First Author: Blumbach K
Year: 2008
Journal: Matrix Biol
Title: Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture.
Volume: 27
Issue: 4
Pages: 306-18
Publication
First Author: Suleman F
Year: 2012
Journal: Hum Mutat
Title: A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia.
Volume: 33
Issue: 1
Pages: 218-31
Publication
First Author: Burger A
Year: 2020
Journal: Mol Genet Genomic Med
Title: Mutant COMP shapes growth and development of skull and facial structures in mice and humans.
Volume: 8
Issue: 7
Pages: e1251
Publication
First Author: Piróg KA
Year: 2013
Journal: PLoS One
Title: Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases.
Volume: 8
Issue: 11
Pages: e82412
Allele  
Name: cartilage oligomeric matrix protein; targeted mutation 2.1, Michael Briggs
Allele Type: Targeted
Publication categories: ProxyCollection
Protein
Organism: Mus musculus
Length: 759  
Fragment?: true
Publication  
First Author: Posey KL
Year: 2014
Journal: Matrix Biol
Title: Pseudoachondroplasia/COMP - translating from the bench to the bedside.
Volume: 37
Pages: 167-73
Publication
First Author: Svensson L
Year: 2002
Journal: Mol Cell Biol
Title: Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.
Volume: 22
Issue: 12
Pages: 4366-71
Publication
First Author: Schulz JN
Year: 2016
Journal: J Cell Sci
Title: COMP-assisted collagen secretion--a novel intracellular function required for fibrosis.
Volume: 129
Issue: 4
Pages: 706-16
Publication
First Author: Kong L
Year: 2010
Journal: Matrix Biol
Title: Interaction between cartilage oligomeric matrix protein and extracellular matrix protein 1 mediates endochondral bone growth.
Volume: 29
Issue: 4
Pages: 276-86
Publication
First Author: Piróg-Garcia KA
Year: 2007
Journal: Hum Mol Genet
Title: Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP.
Volume: 16
Issue: 17
Pages: 2072-88
Publication  
First Author: Papadakos KS
Year: 2019
Journal: Matrix Biol
Title: Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling.
Volume: 81
Pages: 107-121
Publication
First Author: Sengul A
Year: 2012
Journal: Physiol Res
Title: Bone response to loading in mice with targeted disruption of the cartilage oligomeric matrix protein gene.
Volume: 61
Issue: 6
Pages: 637-41
Publication
First Author: Liu CJ
Year: 2006
Journal: J Biol Chem
Title: ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein.
Volume: 281
Issue: 23
Pages: 15800-8
Publication
First Author: Piróg KA
Year: 2010
Journal: Hum Mol Genet
Title: A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia.
Volume: 19
Issue: 1
Pages: 52-64
Publication
First Author: Wang M
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence.
Volume: 478
Issue: 2
Pages: 1006-13
Publication
First Author: Bell PA
Year: 2013
Journal: Biol Open
Title: Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures.
Volume: 2
Issue: 8
Pages: 802-11
Publication
First Author: Liang Y
Year: 2015
Journal: Blood
Title: Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.
Volume: 126
Issue: 7
Pages: 905-14
Publication
First Author: Piróg KA
Year: 2014
Journal: PLoS One
Title: Abnormal chondrocyte apoptosis in the cartilage growth plate is influenced by genetic background and deletion of CHOP in a targeted mouse model of pseudoachondroplasia.
Volume: 9
Issue: 2
Pages: e85145
Publication  
First Author: Coustry F
Year: 2018
Journal: Matrix Biol
Title: Mutant cartilage oligomeric matrix protein (COMP) compromises bone integrity, joint function and the balance between adipogenesis and osteogenesis.
Volume: 67
Pages: 75-89
Publication
First Author: Fu Y
Year: 2016
Journal: Circ Res
Title: Shift of Macrophage Phenotype Due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification.
Volume: 119
Issue: 2
Pages: 261-76
Publication
First Author: Du Y
Year: 2011
Journal: Circ Res
Title: Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.
Volume: 108
Issue: 8
Pages: 917-28
Publication
First Author: Xu K
Year: 2007
Journal: J Biol Chem
Title: Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation.
Volume: 282
Issue: 15
Pages: 11347-55
Publication
First Author: Groma G
Year: 2012
Journal: Arthritis Rheum
Title: Abnormal bone quality in cartilage oligomeric matrix protein and matrilin 3 double-deficient mice caused by increased tissue inhibitor of metalloproteinases 3 deposition and delayed aggrecan degradation.
Volume: 64
Issue: 8
Pages: 2644-54
Publication
First Author: Flowers SA
Year: 2017
Journal: Sci Rep
Title: Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.
Volume: 7
Issue: 1
Pages: 13149
Publication
First Author: Murphy JM
Year: 1999
Journal: Matrix Biol
Title: Distribution of cartilage molecules in the developing mouse joint.
Volume: 18
Issue: 5
Pages: 487-97
Publication
First Author: Newton G
Year: 1994
Journal: Genomics
Title: Characterization of human and mouse cartilage oligomeric matrix protein.
Volume: 24
Issue: 3
Pages: 435-9
Author
Publication
First Author: Strathmann EA
Year: 2018
Journal: PLoS One
Title: Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice.
Volume: 13
Issue: 9
Pages: e0203398
Publication
First Author: Brachvogel B
Year: 2013
Journal: J Biol Chem
Title: Comparative proteomic analysis of normal and collagen IX null mouse cartilage reveals altered extracellular matrix composition and novel components of the collagen IX interactome.
Volume: 288
Issue: 19
Pages: 13481-92
Publication
First Author: Posey KL
Year: 2012
Journal: Am J Pathol
Title: Chop (Ddit3) is essential for D469del-COMP retention and cell death in chondrocytes in an inducible transgenic mouse model of pseudoachondroplasia.
Volume: 180
Issue: 2
Pages: 727-37
Protein
Organism: Mus musculus
Length: 755  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Fang C
Year: 2000
Journal: J Orthop Res
Title: Molecular cloning, sequencing, and tissue and developmental expression of mouse cartilage oligomeric matrix protein (COMP).
Volume: 18
Issue: 4
Pages: 593-603
Publication
First Author: Di Cesare PE
Year: 2000
Journal: J Orthop Res
Title: Expression of cartilage oligomeric matrix protein (COMP) by embryonic and adult osteoblasts.
Volume: 18
Issue: 5
Pages: 713-20
Publication
First Author: Posey KL
Year: 2019
Journal: Am J Pathol
Title: Novel mTORC1 Mechanism Suggests Therapeutic Targets for COMPopathies.
Volume: 189
Issue: 1
Pages: 132-146
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6507713
Age: postnatal adult
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6507714
Age: postnatal adult
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6507713
Age: postnatal adult
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6507714
Age: postnatal adult
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:6507710
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:6507711
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:6507710
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:6507711
Age: postnatal adult
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3526228
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6507713
Age: postnatal adult
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706828
Stage: TS28
Assay Id: MGI:6507714
Age: postnatal adult
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2509128
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619328
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: false
Specimen Num: 14
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514928
Stage: TS28
Assay Id: MGI:5140081
Age: postnatal day 40
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514928
Stage: TS28
Assay Id: MGI:5140081
Age: postnatal month 4
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514928
Stage: TS28
Assay Id: MGI:5140081
Age: postnatal month 6
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514928
Stage: TS28
Assay Id: MGI:5140081
Age: postnatal month 10
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:6507716
Assay Type: Western blot
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514928
Stage: TS28
Assay Id: MGI:6507717
Age: postnatal week 5.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3550428
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: false
Specimen Num: 16
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6507710
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6507711
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278228
Stage: TS28
Assay Id: MGI:6507710
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278228
Stage: TS28
Assay Id: MGI:6507711
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6507710
Age: postnatal adult
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6507711
Age: postnatal adult
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6507710
Age: embryonic day 19.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6507711
Age: embryonic day 19.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6507713
Age: postnatal adult
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6507714
Age: postnatal adult
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550528
Stage: TS28
Assay Id: MGI:5140033
Age: postnatal day 4
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550528
Stage: TS28
Assay Id: MGI:5140081
Age: postnatal day 5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550528
Stage: TS28
Assay Id: MGI:5140081
Age: postnatal day 10
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550528
Stage: TS28
Assay Id: MGI:5140081
Age: postnatal day 15
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5140017
Assay Type: Northern blot
Annotation Date: 2011-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550528
Stage: TS28
Assay Id: MGI:5140081
Age: postnatal day 20
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6507708
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685328
Stage: TS28
Assay Id: MGI:6507710
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6507709
Assay Type: RT-PCR
Annotation Date: 2021-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685328
Stage: TS28
Assay Id: MGI:6507711
Age: postnatal adult
Detected: true
Specimen Num: 5