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Search results 1 to 100 out of 675 for Comt

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Myöhänen TT
Year: 2010
Journal: J Neurochem
Title: Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice.
Volume: 113
Issue: 6
Pages: 1632-43
Publication
First Author: Sannino S
Year: 2017
Journal: Transl Psychiatry
Title: Adolescence is the starting point of sex-dichotomous COMT genetic effects.
Volume: 7
Issue: 5
Pages: e1141
Publication
First Author: Simpson EH
Year: 2014
Journal: Learn Mem
Title: Genetic variation in COMT activity impacts learning and dopamine release capacity in the striatum.
Volume: 21
Issue: 4
Pages: 205-14
Publication
First Author: Käenmäki M
Year: 2009
Journal: Br J Pharmacol
Title: Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice.
Volume: 158
Issue: 8
Pages: 1884-94
Publication
First Author: Babovic D
Year: 2007
Journal: Behav Brain Res
Title: Exploratory and habituation phenotype of heterozygous and homozygous COMT knockout mice.
Volume: 183
Issue: 2
Pages: 236-9
Publication
First Author: Barkus C
Year: 2016
Journal: Neuropsychopharmacology
Title: Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly Specific, Novel Mouse Model of Altered COMT Activity.
Volume: 41
Issue: 13
Pages: 3060-3069
Publication
First Author: Segall SK
Year: 2015
Journal: Pain
Title: Molecular genetic mechanisms of allelic specific regulation of murine Comt expression.
Volume: 156
Issue: 10
Pages: 1965-1977
Publication  
First Author: Odlind C
Year: 2002
Journal: BMC Physiol
Title: Reduced natriuretic response to acute sodium loading in COMT gene deleted mice.
Volume: 2
Pages: 14
GXD Expression  
Probe: MGI:5588110
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5588111
Age: postnatal adult
Image: 4 cerebellum COMT
Specimen Label: 4 cerebellum COMT
Detected: true
Specimen Num: 3
Publication
First Author: Käenmäki M
Year: 2010
Journal: J Neurochem
Title: Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice.
Volume: 114
Issue: 6
Pages: 1745-55
Publication
First Author: Papaleo F
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Effects of sex and COMT genotype on environmentally modulated cognitive control in mice.
Volume: 109
Issue: 49
Pages: 20160-5
Publication
First Author: O'Tuathaigh CM
Year: 2010
Journal: Neuropsychopharmacology
Title: Chronic adolescent exposure to Δ-9-tetrahydrocannabinol in COMT mutant mice: impact on psychosis-related and other phenotypes.
Volume: 35
Issue: 11
Pages: 2262-73
Publication
First Author: Li Z
Year: 2010
Journal: PLoS One
Title: A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice.
Volume: 5
Issue: 8
Pages: e12181
Publication  
First Author: Walsh J
Year: 2010
Journal: Brain Res
Title: Disruption of thermal nociceptive behaviour in mice mutant for the schizophrenia-associated genes NRG1, COMT and DISC1.
Volume: 1348
Pages: 114-9
Publication
First Author: Papaleo F
Year: 2014
Journal: Mol Psychiatry
Title: Epistatic interaction between COMT and DTNBP1 modulates prefrontal function in mice and in humans.
Volume: 19
Issue: 3
Pages: 311-6
Publication
First Author: Sannino S
Year: 2015
Journal: Cereb Cortex
Title: COMT Genetic Reduction Produces Sexually Divergent Effects on Cortical Anatomy and Working Memory in Mice and Humans.
Volume: 25
Issue: 9
Pages: 2529-41
Publication
First Author: Yeung RS
Year: 1996
Journal: Mamm Genome
Title: The Vpreb1 and comt genes are closely linked and sublocalized to rat chromosome 11q23.
Volume: 7
Issue: 3
Pages: 246-7
GXD Expression      
Probe: MGI:6170178
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190029
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Comt
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6170178
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190029
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Comt
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6170178
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190029
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Comt
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6170178
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190029
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Comt
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6170178
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190029
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Comt
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6170178
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190029
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Comt
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6170178
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190029
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Comt
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3028125
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5588035
Age: postnatal adult
Image: 6 striatum CDCrel-1 + Comt
Specimen Label: 6 striatum CDCrel-1 + Comt
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3028125
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5588035
Age: postnatal adult
Image: 6 cortex CDCrel-1 + Comt
Specimen Label: 6 cortex CDCrel-1 + Comt
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3028125
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5588035
Age: postnatal adult
Image: 6 hippocampus CDCrel-1 + Comt
Specimen Label: 6 hippocampus CDCrel-1 + Comt
Detected: true
Specimen Num: 2
Publication
First Author: Kanasaki M
Year: 2017
Journal: Sci Rep
Title: Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice.
Volume: 7
Issue: 1
Pages: 7927
Publication
First Author: Stubelius A
Year: 2012
Journal: Immunobiology
Title: Sexual dimorphisms in the immune system of catechol-O-methyltransferase knockout mice.
Volume: 217
Issue: 8
Pages: 751-60
Publication
First Author: Zacharia LC
Year: 2003
Journal: Circulation
Title: Methoxyestradiols mediate the antimitogenic effects of 17beta-estradiol: direct evidence from catechol-O-methyltransferase-knockout mice.
Volume: 108
Issue: 24
Pages: 2974-8
Publication
First Author: Tammimäki A
Year: 2008
Journal: Basic Clin Pharmacol Toxicol
Title: Increase in free choice oral ethanol self-administration in catechol-o-methyltransferase gene-disrupted male mice.
Volume: 103
Issue: 4
Pages: 297-304
Publication
First Author: Tenorio-Laranga J
Year: 2009
Journal: Biochem Pharmacol
Title: Sex-dependent compensated oxidative stress in the mouse liver upon deletion of catechol O-methyltransferase.
Volume: 77
Issue: 9
Pages: 1541-52
Publication
First Author: Gogos JA
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior.
Volume: 95
Issue: 17
Pages: 9991-6
Publication
First Author: Risbrough V
Year: 2014
Journal: Neuropsychopharmacology
Title: Generation and characterization of humanized mice carrying COMT158 Met/Val alleles.
Volume: 39
Issue: 8
Pages: 1823-32
Publication
First Author: Kember RL
Year: 2010
Journal: Genes Brain Behav
Title: A B2 SINE insertion in the Comt1 gene (Comt1(B2i)) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains.
Volume: 9
Issue: 8
Pages: 925-32
Publication
First Author: Segall SK
Year: 2010
Journal: Genes Brain Behav
Title: Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice.
Volume: 9
Issue: 8
Pages: 933-46
Publication
First Author: Desbonnet L
Year: 2012
Journal: Behav Brain Res
Title: Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice.
Volume: 228
Issue: 2
Pages: 351-8
Publication
First Author: Yavich L
Year: 2007
Journal: J Neurosci
Title: Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum.
Volume: 27
Issue: 38
Pages: 10196-209
Publication
First Author: Lee SB
Year: 2010
Journal: Am J Pathol
Title: Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions.
Volume: 176
Issue: 2
Pages: 710-20
Publication
First Author: Schendzielorz N
Year: 2012
Journal: Basic Clin Pharmacol Toxicol
Title: A transient inhibition and permanent lack of catechol-O-methyltransferase have minor effects on feeding pattern of female rodents.
Volume: 110
Issue: 4
Pages: 307-13
Publication
First Author: Huotari M
Year: 2002
Journal: Eur J Neurosci
Title: Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice.
Volume: 15
Issue: 2
Pages: 246-56
Publication
First Author: Papaleo F
Year: 2008
Journal: J Neurosci
Title: Genetic dissection of the role of catechol-O-methyltransferase in cognition and stress reactivity in mice.
Volume: 28
Issue: 35
Pages: 8709-23
Publication
First Author: Kambur O
Year: 2008
Journal: Basic Clin Pharmacol Toxicol
Title: Stress-induced analgesia and morphine responses are changed in catechol-O-methyltransferase-deficient male mice.
Volume: 103
Issue: 4
Pages: 367-73
Publication
First Author: Herndon JM
Year: 2014
Journal: Toxicol Sci
Title: Catechol-o-methyltransferase and 3,4-({+/-})-methylenedioxymethamphetamine toxicity.
Volume: 139
Issue: 1
Pages: 162-73
Publication
First Author: Seeman P
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis.
Volume: 102
Issue: 9
Pages: 3513-8
Publication
First Author: Tammimaki A
Year: 2016
Journal: J Physiol Pharmacol
Title: Generation of membrane-bound catechol-O-methyl transferase deficient mice with disctinct sex dependent behavioral phenotype.
Volume: 67
Issue: 6
Pages: 827-842
Publication  
First Author: Deslauriers J
Year: 2019
Journal: Front Behav Neurosci
Title: Heritable Differences in Catecholamine Signaling Modulate Susceptibility to Trauma and Response to Methylphenidate Treatment: Relevance for PTSD.
Volume: 13
Pages: 111
Publication
First Author: Parchem JG
Year: 2018
Journal: J Clin Invest
Title: Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice.
Volume: 128
Issue: 11
Pages: 5008-5017
Publication
First Author: Zhang MZ
Year: 2012
Journal: Diabetes
Title: Intrarenal dopamine inhibits progression of diabetic nephropathy.
Volume: 61
Issue: 10
Pages: 2575-84
Publication
First Author: Yang S
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury.
Volume: 302
Issue: 6
Pages: F742-9
Publication
First Author: Ciampoli M
Year: 2017
Journal: Sci Rep
Title: Attentional Control in Adolescent Mice Assessed with a Modified Five Choice Serial Reaction Time Task.
Volume: 7
Issue: 1
Pages: 9936
Publication
First Author: Bućan M
Year: 1993
Journal: Hum Mol Genet
Title: Comparative mapping of 9 human chromosome 22q loci in the laboratory mouse.
Volume: 2
Issue: 8
Pages: 1245-52
Publication
First Author: Wilhelmson AS
Year: 2011
Journal: Endocrinology
Title: Catechol-O-methyltransferase is dispensable for vascular protection by estradiol in mouse models of atherosclerosis and neointima formation.
Volume: 152
Issue: 12
Pages: 4683-90
Publication
First Author: Sizova D
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Renalase regulates renal dopamine and phosphate metabolism.
Volume: 305
Issue: 6
Pages: F839-44
Publication
First Author: Zhou Q
Year: 2023
Journal: Gastroenterology
Title: Catechol-O-Methyltransferase Loss Drives Cell-Specific Nociceptive Signaling via the Enteric Catechol-O-Methyltransferase/microRNA-155/Tumor Necrosis Factor α Axis.
Volume: 164
Issue: 4
Pages: 630-641.e34
Publication
First Author: Kanasaki K
Year: 2008
Journal: Nature
Title: Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia.
Volume: 453
Issue: 7198
Pages: 1117-21
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Palmer AA
Year: 2010
Journal: Front Neurosci
Title: Murine Warriors or Worriers: The Saga of Comt1, B2 SINE Elements, and the Future of Translational Genetics.
Volume: 4
Pages: 177
Publication
First Author: Koppel J
Year: 2019
Journal: J Neurochem
Title: Increased tau phosphorylation follows impeded dopamine clearance in a P301L and novel P301L/COMT-deleted (DM) tau mouse model.
Volume: 148
Issue: 1
Pages: 127-135
Publication
First Author: Babovic D
Year: 2008
Journal: Neuroscience
Title: Phenotypic characterization of cognition and social behavior in mice with heterozygous versus homozygous deletion of catechol-O-methyltransferase.
Volume: 155
Issue: 4
Pages: 1021-9
Publication
First Author: Yao B
Year: 2009
Journal: Hypertension
Title: Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway.
Volume: 54
Issue: 5
Pages: 1077-83
Publication
First Author: Lipson RS
Year: 2007
Journal: J Biol Chem
Title: S-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-O-methyltransferase.
Volume: 282
Issue: 42
Pages: 31094-102
GXD Expression      
Probe: MGI:1332125
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332126
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1332125
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332126
Age: embryonic day 7.5
Specimen Label: 10x
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1332125
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:1332126
Age: embryonic day 7.5
Specimen Label: 100x
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:1332125
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332126
Age: embryonic day 7.5
Specimen Label: 1x
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1332125
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332126
Age: embryonic day 7.5
Specimen Label: 10x
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1332125
Assay Type: RT-PCR
Annotation Date: 1999-03-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604211
Stage: TS11
Assay Id: MGI:1332126
Age: embryonic day 7.5
Specimen Label: 100x
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3028096
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689517
Stage: TS17
Assay Id: MGI:3028157
Age: embryonic day 10.5
Image: 1
Specimen Label: fnm/fb
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3028096
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611717
Stage: TS17
Assay Id: MGI:3028157
Age: embryonic day 10.5
Image: 1
Specimen Label: ba
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3028096
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610417
Stage: TS17
Assay Id: MGI:3028157
Age: embryonic day 10.5
Image: 1
Specimen Label: aah
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3028096
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Stage: TS17
Assay Id: MGI:3028157
Age: embryonic day 10.5
Image: 1
Specimen Label: flb
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3028097
Assay Type: RT-PCR
Annotation Date: 2004-02-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689517
Stage: TS17
Assay Id: MGI:3028158
Age: embryonic day 10.5
Image: 1
Specimen Label: fnm/fb
Detected: true
Specimen Num: 1