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Search results 1 to 100 out of 368 for Cop1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Protein Domain
Type: Family
Description: COP1 is a RING finger-type ubiquitin E3 ligase. In Arabidopsis, it is a central switch for the transition from plant growth underground in darkness (etiolation) to growth under light exposure (photomorphogenesis) []. In mammals, it functions as an E3 ubiquitin-protein ligase involved in tumorigenesis, gluconeogenesis, and lipid metabolism. It is regulated by the COP9 signalosome []and is involved in 14-3-3 delta ubiquitin-mediated degradation []. COP1 contains a classic leucine-rich NES and a novel bipartite NLS bridged by a RING finger domain [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 159  
Fragment?: false
Protein
Organism: Mus musculus
Length: 227  
Fragment?: true
Protein
Organism: Mus musculus
Length: 733  
Fragment?: false
Protein
Organism: Mus musculus
Length: 202  
Fragment?: true
Protein
Organism: Mus musculus
Length: 155  
Fragment?: true
Protein
Organism: Mus musculus
Length: 346  
Fragment?: true
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication  
First Author: Yi C
Year: 2002
Journal: BMC Cell Biol
Title: An initial biochemical and cell biological characterization of the mammalian homologue of a central plant developmental switch, COP1.
Volume: 3
Pages: 30
Publication
First Author: Sanchez-Barcelo EJ
Year: 2016
Journal: J Pineal Res
Title: Constitutive photomorphogenesis protein 1 (COP1) and COP9 signalosome, evolutionarily conserved photomorphogenic proteins as possible targets of melatonin.
Volume: 61
Issue: 1
Pages: 41-51
Publication
First Author: Choi HH
Year: 2011
Journal: Oncogene
Title: COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ.
Volume: 30
Issue: 48
Pages: 4791-801
Publication
First Author: Wang H
Year: 1999
Journal: Curr Biol
Title: Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1.
Volume: 9
Issue: 13
Pages: 711-4
Publication
First Author: Srivastava AK
Year: 2015
Journal: Plant Physiol
Title: Short Hypocotyl in White Light1 Interacts with Elongated Hypocotyl5 (HY5) and Constitutive Photomorphogenic1 (COP1) and Promotes COP1-Mediated Degradation of HY5 during Arabidopsis Seedling Development.
Volume: 169
Issue: 4
Pages: 2922-34
Publication
First Author: Vitari AC
Year: 2011
Journal: Nature
Title: COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Volume: 474
Issue: 7351
Pages: 403-6
Publication
First Author: Qi L
Year: 2006
Journal: Science
Title: TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.
Volume: 312
Issue: 5781
Pages: 1763-6
Publication
First Author: Li DQ
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1.
Volume: 106
Issue: 41
Pages: 17493-8
Publication
First Author: Migliorini D
Year: 2011
Journal: J Clin Invest
Title: Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.
Volume: 121
Issue: 4
Pages: 1329-43
Protein
Organism: Mus musculus
Length: 733  
Fragment?: false
Publication
First Author: Newton K
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain.
Volume: 115
Issue: 44
Pages: 11244-11249
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Rizzini L
Year: 2019
Journal: Curr Biol
Title: Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism.
Volume: 29
Issue: 12
Pages: 1954-1962.e4
Publication
First Author: Suriben R
Year: 2015
Journal: Cell
Title: β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.
Volume: 163
Issue: 6
Pages: 1457-67
Publication
First Author: Zhang Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor Etv5 is essential for the maintenance of alveolar type II cells.
Volume: 114
Issue: 15
Pages: 3903-3908
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691621
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691627
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777821
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Note: The tissue was olfactory epithelium and/or bulb.
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754921
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754927
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697421
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697427
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:6144
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11936
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665921
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665927
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716821
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619321
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Note: The tissue was inner ear and ear structures.
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619327
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Note: The tissue was inner ear and ear structures.
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2853323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:6144
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11936
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753621
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753627
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:6144
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11936
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778727
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666821
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647021
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647027
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3509471
Age: embryonic day 10.5
Image: 1
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:6144
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11936
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185821
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185827
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:6144
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11936
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:6144
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11936
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:6144
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11936
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754021
Stage: TS21
Assay Id: MGI:3508235
Age: embryonic day 13.5
Image: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754027
Stage: TS27
Assay Id: MGI:3508235
Age: postnatal newborn
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:6144
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506793
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539765
Age: embryonic day 15.5
Image: GUDMAP:11843
Detected: true
Specimen Num: 2