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Search results 1 to 100 out of 335 for Coro1a

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Hits by Strain

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Type Details Score
Gene
11151 | CORO1A
Type: gene
Organism: human
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Gene
454038 | CORO1A
Type: gene
Organism: chimpanzee
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Gene
100002113 | coro1a
Type: gene
Organism: zebrafish
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Gene
710813 | CORO1A
Type: gene
Organism: macaque, rhesus
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Gene
448298 | coro1a
Type: gene
Organism: frog, western clawed
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Gene
282196 | CORO1A
Type: gene
Organism: cattle
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Gene
155151 | Coro1a
Type: gene
Organism: rat
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Gene
489949 | CORO1A
Type: gene
Organism: dog, domestic
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Protein Domain
IPR029508 | CORO1A
Type: Family
Description: Coronins belongs to the WD40-repeat family, which contains the WD40 motifs that act as the protein-protein interaction sites. There are several isoforms of Coronin in mammalian cells []. Coronin-1a, primarily expressed in hematopoietic cells, has been proposed to be an actin regulatory protein that functions as a bridging protein between the plasma membrane and the actin cytoskeleton of leukocytes. This may serve to integrate outside-inside signaling with modulation of the cytoskeleton []. However, Coronin-1a may also have actin-independent functions []. Coronin-1a inhibits autophagosome formation around Mycobacterium tuberculosis-containing phagosomes. This way the intracellular pathogen Mycobacteria can survive within macrophage phagosomes [, ].
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Protein Coding Gene
MGI:1345961 | Coro1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
107984834 | CORO1A-AS1
Type: gene
Organism: human
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Publication
18345003 | J:133258
First Author: Mueller P
Year: 2008
Journal: Nat Immunol
Title: Regulation of T cell survival through coronin-1-mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering.
Volume: 9
Issue: 4
Pages: 424-31
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Publication
15800061 | J:100752
First Author: Gatfield J
Year: 2005
Journal: Mol Biol Cell
Title: Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules.
Volume: 16
Issue: 6
Pages: 2786-98
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Publication
10461187 | J:56832
First Author: de Hostos EL
Year: 1999
Journal: Trends Cell Biol
Title: The coronin family of actin-associated proteins.
Volume: 9
Issue: 9
Pages: 345-50
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Publication
10338208 | -
First Author: Ferrari G
Year: 1999
Journal: Cell
Title: A coat protein on phagosomes involved in the intracellular survival of mycobacteria.
Volume: 97
Issue: 4
Pages: 435-47
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Protein
O89053
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q3U1N0
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
Q3U9K3
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
A0A0U1RPY8
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: true
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Protein
G3UYK8
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: false
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Protein
D3YXM2
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
Q3U232
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
G3UX53
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: true
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Protein
Q3T9L1
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
D3YW57
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: true
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Publication
22256790 | -
First Author: Seto S
Year: 2012
Journal: Cell Microbiol
Title: Coronin-1a inhibits autophagosome formation around Mycobacterium tuberculosis-containing phagosomes and assists mycobacterial survival in macrophages.
Volume: 14
Issue: 5
Pages: 710-27
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Publication
21844203 | J:177785
First Author: Föger N
Year: 2011
Journal: J Exp Med
Title: Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b.
Volume: 208
Issue: 9
Pages: 1777-87
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Publication
22223354 | J:192698
First Author: Hölttä-Vuori M
Year: 2012
Journal: Circ Res
Title: Endosomal actin remodeling by coronin-1A controls lipoprotein uptake and degradation in macrophages.
Volume: 110
Issue: 3
Pages: 450-5
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Publication
18836449 | J:141431
First Author: Shiow LR
Year: 2008
Journal: Nat Immunol
Title: The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.
Volume: 9
Issue: 11
Pages: 1307-15
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Publication
28615221 | J:243781
First Author: Pick R
Year: 2017
Journal: Blood
Title: Coronin 1A, a novel player in integrin biology, controls neutrophil trafficking in innate immunity.
Volume: 130
Issue: 7
Pages: 847-858
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Publication
21700422 | J:237967
First Author: Kaminski S
Year: 2011
Journal: J Autoimmun
Title: Coronin 1A is an essential regulator of the TGFβ receptor/SMAD3 signaling pathway in Th17 CD4(+) T cells.
Volume: 37
Issue: 3
Pages: 198-208
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Publication
16902139 | J:111593
First Author: Föger N
Year: 2006
Journal: Science
Title: Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis.
Volume: 313
Issue: 5788
Pages: 839-42
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Publication
37837948 | J:342882
First Author: Deng X
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: CREBH promotes autophagy to ameliorate NASH by regulating Coro1a.
Volume: 1870
Issue: 1
Pages: 166914
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Protein Coding Gene
MGP_CAROLIEiJ_G0030460 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032994 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032909 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032982 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032692 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1345961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033488 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032665 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032817 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032770 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032911 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032802 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033507 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031728 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032133 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013670 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031574 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10615997 | J:66460
First Author: Otto JM
Year: 1999
Journal: Arthritis Rheum
Title: Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis.
Volume: 42
Issue: 12
Pages: 2524-31
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Publication
9449705 | J:45708
First Author: Vidal S
Year: 1998
Journal: J Clin Invest
Title: Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.
Volume: 101
Issue: 3
Pages: 696-702
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Publication
23099476 | J:191097
First Author: Westritschnig K
Year: 2013
Journal: Mol Immunol
Title: Antigen processing and presentation by dendritic cells is independent of coronin 1.
Volume: 53
Issue: 4
Pages: 379-86
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Publication
2074115 | J:141679
First Author: Yagi H
Year: 1990
Journal: Immunol Invest
Title: Immune deficiency of cataract Shionogi (CTS) mouse. II. Impaired in vivo T cell-mediated immune response.
Volume: 19
Issue: 5-6
Pages: 493-505
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Publication
8871639 | J:38359
First Author: Yagi H
Year: 1996
Journal: J Immunol
Title: Defect of thymocyte emigration in a T cell deficiency strain (CTS) of the mouse.
Volume: 157
Issue: 8
Pages: 3412-9
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Publication
17632055 | J:133404
First Author: Jayachandran R
Year: 2007
Journal: Cell
Title: Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin.
Volume: 130
Issue: 1
Pages: 37-50
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Publication
19201848 | J:144802
First Author: Combaluzier B
Year: 2009
Journal: J Immunol
Title: Coronin 1 is essential for IgM-mediated Ca2+ mobilization in B cells but dispensable for the generation of immune responses in vivo.
Volume: 182
Issue: 4
Pages: 1954-61
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Publication
21289301 | J:169779
First Author: Siegmund K
Year: 2011
Journal: J Immunol
Title: Coronin 1-mediated naive T cell survival is essential for the development of autoimmune encephalomyelitis.
Volume: 186
Issue: 6
Pages: 3452-61
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Publication
19234169 | J:146257
First Author: Combaluzier B
Year: 2009
Journal: J Immunol
Title: Chemotaxis and phagocytosis in neutrophils is independent of coronin 1.
Volume: 182
Issue: 5
Pages: 2745-52
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Publication
31948107 | J:297130
 
First Author: Riley DRJ
Year: 2020
Journal: Int J Mol Sci
Title: Coronin 1 Is Required for Integrin β2 Translocation in Platelets.
Volume: 21
Issue: 1
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Publication
25740518 | J:219932
First Author: Suo D
Year: 2015
Journal: J Neurosci
Title: Coronin-1 and calcium signaling governs sympathetic final target innervation.
Volume: 35
Issue: 9
Pages: 3893-902
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Publication
23933558 | J:202346
First Author: Tchang VS
Year: 2013
Journal: Mol Immunol
Title: Diverging role for coronin 1 in antiviral CD4+ and CD8+ T cell responses.
Volume: 56
Issue: 4
Pages: 683-92
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Publication
24667537 | J:208639
First Author: Jayachandran R
Year: 2014
Journal: PLoS Biol
Title: Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling.
Volume: 12
Issue: 3
Pages: e1001820
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Publication
21339362 | J:170847
First Author: Mueller P
Year: 2011
Journal: J Immunol
Title: Migration and homeostasis of naive T cells depends on coronin 1-mediated prosurvival signals and not on coronin 1-dependent filamentous actin modulation.
Volume: 186
Issue: 7
Pages: 4039-50
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Publication
28821585 | J:251566
First Author: Lang MJ
Year: 2017
Journal: J Immunol
Title: A Coronin 1-Dependent Decision Switch in Juvenile Mice Determines the Population of the Peripheral Naive T Cell Compartment.
Volume: 199
Issue: 7
Pages: 2421-2431
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Publication
20643816 | J:165609
First Author: Arandjelovic S
Year: 2010
Journal: J Leukoc Biol
Title: Mast cell function is not altered by Coronin-1A deficiency.
Volume: 88
Issue: 4
Pages: 737-45
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Publication
10337629 | J:54435
First Author: Kung C
Year: 1999
Journal: Mamm Genome
Title: Genomic organization and chromosomal localization of mouse coronin-1.
Volume: 10
Issue: 5
Pages: 523-5
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Publication
12144559 | J:78311
 
First Author: Theofilopoulos AN
Year: 2002
Journal: Allergy
Title: A genetic analysis of lupus.
Volume: 57 Suppl 72
Pages: 67-74
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Publication
27566541 | J:237290
First Author: Siegmund K
Year: 2016
Journal: J Biol Chem
Title: Proof of Principle for a T Lymphocyte Intrinsic Function of Coronin 1A.
Volume: 291
Issue: 42
Pages: 22086-22092
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:1346776
Age: embryonic day 7.0
Specimen Label: 7
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:1346776
Age: embryonic day 11.0
Specimen Label: 11
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1346776
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:1346776
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1346781
Age: postnatal adult
Specimen Label: HEART
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1346781
Age: postnatal adult
Specimen Label: BRAIN
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1346781
Age: postnatal adult
Specimen Label: SPLEEN
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1346781
Age: postnatal adult
Specimen Label: LUNG
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1346781
Age: postnatal adult
Specimen Label: LIVER
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1346781
Age: postnatal adult
Specimen Label: SKELETAL MUSCLE
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1346781
Age: postnatal adult
Specimen Label: KIDNEY
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:1346772
Assay Type: Northern blot
Annotation Date: 1999-11-05
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1346781
Age: postnatal adult
Specimen Label: TESTIS
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3708292
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:3708345
Age: embryonic day 13.5
Image: 5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3708292
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:3708345
Age: embryonic day 16.5
Image: 5
Specimen Label: E16.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860414
Specimen Label: UC Davis_1860414
Detected: true
Specimen Num: 93
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860394
Specimen Label: UC Davis_1860394
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860395
Specimen Label: UC Davis_1860395
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860331
Specimen Label: UC Davis_1860331
Detected: true
Specimen Num: 41
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860332
Specimen Label: UC Davis_1860332
Detected: true
Specimen Num: 42
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860333
Specimen Label: UC Davis_1860333
Detected: true
Specimen Num: 43
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860334
Specimen Label: UC Davis_1860334
Detected: true
Specimen Num: 44
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860416
Specimen Label: UC Davis_1860416
Detected: true
Specimen Num: 95
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•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860351
Specimen Label: UC Davis_1860351
Detected: true
Specimen Num: 61
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860352
Specimen Label: UC Davis_1860352
Detected: true
Specimen Num: 62
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860346
Specimen Label: UC Davis_1860346
Detected: true
Specimen Num: 56
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860347
Specimen Label: UC Davis_1860347
Detected: true
Specimen Num: 57
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860419
Specimen Label: UC Davis_1860419
Detected: true
Specimen Num: 96
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860402
Specimen Label: UC Davis_1860402
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691459
Age: postnatal adult
Image: UC Davis_1860403
Specimen Label: UC Davis_1860403
Detected: true
Specimen Num: 12
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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