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Search results 1 to 100 out of 3917 for Cp

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Ceruloplasmin (CP) is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe2+ to Fe3+ without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Ceruloplasmin may also play a role in fetal lung development or pulmonary antioxidant defence. It provides Cu2+ ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1 [, , ]. Defects in CP cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication      
First Author: Dagg CP
Year: 1966
Title: Teratogenesis
Pages: 309-28
Publication
First Author: Bento I
Year: 2007
Journal: Acta Crystallogr D Biol Crystallogr
Title: Ceruloplasmin revisited: structural and functional roles of various metal cation-binding sites.
Volume: 63
Issue: Pt 2
Pages: 240-8
Publication
First Author: Mani K
Year: 2004
Journal: J Biol Chem
Title: Involvement of glycosylphosphatidylinositol-linked ceruloplasmin in the copper/zinc-nitric oxide-dependent degradation of glypican-1 heparan sulfate in rat C6 glioma cells.
Volume: 279
Issue: 13
Pages: 12918-23
Publication  
First Author: Hellman NE
Year: 2002
Journal: Annu Rev Nutr
Title: Ceruloplasmin metabolism and function.
Volume: 22
Pages: 439-58
Publication
First Author: Harned J
Year: 2012
Journal: Exp Eye Res
Title: Ceruloplasmin alters intracellular iron regulated proteins and pathways: ferritin, transferrin receptor, glutamate and hypoxia-inducible factor-1α.
Volume: 97
Issue: 1
Pages: 90-7
Protein
Organism: Mus musculus
Length: 57  
Fragment?: true
Protein
Organism: Mus musculus
Length: 120  
Fragment?: true
Protein
Organism: Mus musculus
Length: 197  
Fragment?: true
Protein
Organism: Mus musculus
Length: 434  
Fragment?: false
Protein
Organism: Mus musculus
Length: 503  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1061  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1085  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1060  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1086  
Fragment?: false
Publication
First Author: Blobel CP
Year: 1997
Journal: Cell
Title: Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNF alpha and Notch.
Volume: 90
Issue: 4
Pages: 589-92
Publication
First Author: Dagg CP
Year: 1967
Journal: J Exp Zool
Title: Combined action of fluorouracil and two mutant genes on limb development in the mouse.
Volume: 164
Issue: 3
Pages: 479-89
Publication
First Author: Gouya L
Year: 2007
Journal: Gastroenterology
Title: Genetic study of variation in normal mouse iron homeostasis reveals ceruloplasmin as an HFE-hemochromatosis modifier gene.
Volume: 132
Issue: 2
Pages: 679-86
Publication
First Author: Glezer I
Year: 2007
Journal: PLoS One
Title: Genes involved in the balance between neuronal survival and death during inflammation.
Volume: 2
Issue: 3
Pages: e310
Publication
First Author: Cherukuri S
Year: 2005
Journal: Cell Metab
Title: Unexpected role of ceruloplasmin in intestinal iron absorption.
Volume: 2
Issue: 5
Pages: 309-19
Publication
First Author: Rathore KI
Year: 2008
Journal: J Neurosci
Title: Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.
Volume: 28
Issue: 48
Pages: 12736-47
Publication
First Author: Kaneko K
Year: 2008
Journal: Neurosci Lett
Title: Increased vulnerability to rotenone-induced neurotoxicity in ceruloplasmin-deficient mice.
Volume: 446
Issue: 1
Pages: 56-8
Publication
First Author: Zheng J
Year: 2018
Journal: FEBS Lett
Title: Ablation of hephaestin and ceruloplasmin results in iron accumulation in adipocytes and type 2 diabetes.
Volume: 592
Issue: 3
Pages: 394-401
Publication
First Author: Chen H
Year: 2010
Journal: J Nutr
Title: Identification of zyklopen, a new member of the vertebrate multicopper ferroxidase family, and characterization in rodents and human cells.
Volume: 140
Issue: 10
Pages: 1728-35
Publication
First Author: Cherukuri S
Year: 2004
Journal: Blood Cells Mol Dis
Title: Anemia and impaired stress-induced erythropoiesis in aceruloplasminemic mice.
Volume: 33
Issue: 3
Pages: 346-55
Publication
First Author: Texel SJ
Year: 2011
Journal: PLoS One
Title: Ceruloplasmin deficiency reduces levels of iron and BDNF in the cortex and striatum of young mice and increases their vulnerability to stroke.
Volume: 6
Issue: 9
Pages: e25077
Publication
First Author: Yamamoto K
Year: 2002
Journal: Biochim Biophys Acta
Title: Quantitative evaluation of expression of iron-metabolism genes in ceruloplasmin-deficient mice.
Volume: 1588
Issue: 3
Pages: 195-202
Publication  
First Author: You LH
Year: 2015
Journal: Neuroscience
Title: Brain iron accumulation exacerbates the pathogenesis of MPTP-induced Parkinson's disease.
Volume: 284
Pages: 234-46
Publication
First Author: Texel SJ
Year: 2012
Journal: J Neurochem
Title: Ceruloplasmin deficiency results in an anxiety phenotype involving deficits in hippocampal iron, serotonin, and BDNF.
Volume: 120
Issue: 1
Pages: 125-34
Publication
First Author: Jeong SY
Year: 2006
Journal: J Neurosci
Title: Age-related changes in iron homeostasis and cell death in the cerebellum of ceruloplasmin-deficient mice.
Volume: 26
Issue: 38
Pages: 9810-9
Publication
First Author: Hahn P
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration.
Volume: 101
Issue: 38
Pages: 13850-5
Publication
First Author: Wolkow N
Year: 2012
Journal: Am J Pathol
Title: Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.
Volume: 180
Issue: 4
Pages: 1614-24
Publication
First Author: Zhao L
Year: 2015
Journal: J Neurochem
Title: Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone.
Volume: 135
Issue: 5
Pages: 958-74
Publication
First Author: Xu E
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis.
Volume: 503
Issue: 3
Pages: 1905-1910
Publication
First Author: Baranov VS
Year: 1987
Journal: Chromosoma
Title: Chromosomal localization of ceruloplasmin and transferrin genes in laboratory rats, mice and in man by hybridization with specific DNA probes.
Volume: 96
Issue: 1
Pages: 60-6
Publication  
First Author: Chen M
Year: 2018
Journal: Redox Biol
Title: Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux.
Volume: 17
Pages: 432-439
Publication  
First Author: Jiang B
Year: 2016
Journal: Sci Rep
Title: Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney.
Volume: 6
Pages: 39470
Publication  
First Author: Ryan F
Year: 2018
Journal: Front Neurosci
Title: Ceruloplasmin Plays a Neuroprotective Role in Cerebral Ischemia.
Volume: 12
Pages: 988
Publication
First Author: Jiang R
Year: 2015
Journal: J Nutr
Title: Hephaestin and ceruloplasmin play distinct but interrelated roles in iron homeostasis in mouse brain.
Volume: 145
Issue: 5
Pages: 1003-9
Publication
First Author: Ponting CP
Year: 2000
Journal: Trends Biochem Sci
Title: Novel repeats in ryanodine and IP3 receptors and protein O-mannosyltransferases.
Volume: 25
Issue: 2
Pages: 48-50
Publication
First Author: Ponting CP
Year: 1997
Journal: Protein Sci
Title: Evidence for PDZ domains in bacteria, yeast, and plants.
Volume: 6
Issue: 2
Pages: 464-8
Publication
First Author: Ponting CP
Year: 1996
Journal: Protein Sci
Title: Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains?
Volume: 5
Issue: 11
Pages: 2353-7
Publication
First Author: Ponting CP
Year: 1995
Journal: Trends Biochem Sci
Title: AF-6/cno: neither a kinesin nor a myosin, but a bit of both.
Volume: 20
Issue: 7
Pages: 265-6
Publication
First Author: Ponting CP
Year: 1997
Journal: Trends Biochem Sci
Title: Tudor domains in proteins that interact with RNA.
Volume: 22
Issue: 2
Pages: 51-2
Publication
First Author: Ponting CP
Year: 1999
Journal: J Mol Med (Berl)
Title: Raf-like Ras/Rap-binding domains in RGS12- and still-life-like signalling proteins.
Volume: 77
Issue: 10
Pages: 695-8
Publication
First Author: Ponting CP
Year: 2000
Journal: Trends Biochem Sci
Title: Novel eIF4G domain homologues linking mRNA translation with nonsense-mediated mRNA decay.
Volume: 25
Issue: 9
Pages: 423-6
Publication  
First Author: Ponting CP
Year: 2000
Journal: Biochem J
Title: Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction.
Volume: 351 Pt 2
Pages: 527-35
Publication
First Author: Whitman CP
Year: 2002
Journal: Arch Biochem Biophys
Title: The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif.
Volume: 402
Issue: 1
Pages: 1-13
Publication
First Author: Ponting CP
Year: 2002
Journal: Nucleic Acids Res
Title: Novel domains and orthologues of eukaryotic transcription elongation factors.
Volume: 30
Issue: 17
Pages: 3643-52
Publication
First Author: Ponting CP
Year: 2001
Journal: Hum Mol Genet
Title: Domain homologues of dopamine beta-hydroxylase and ferric reductase: roles for iron metabolism in neurodegenerative disorders?
Volume: 10
Issue: 17
Pages: 1853-8
Publication
First Author: Ponting CP
Year: 1994
Journal: Protein Sci
Title: Acid sphingomyelinase possesses a domain homologous to its activator proteins: saposins B and D.
Volume: 3
Issue: 2
Pages: 359-61
Publication
First Author: Ponting CP
Year: 1997
Journal: Protein Sci
Title: P100, a transcriptional coactivator, is a human homologue of staphylococcal nuclease.
Volume: 6
Issue: 2
Pages: 459-63
Publication
First Author: Ponting CP
Year: 1999
Journal: Curr Biol
Title: Chlamydial homologues of the MACPF (MAC/perforin) domain.
Volume: 9
Issue: 24
Pages: R911-3
Publication  
First Author: Wolk CP
Year: 1996
Journal: Annu Rev Genet
Title: Heterocyst formation.
Volume: 30
Pages: 59-78
Publication
First Author: Ponting CP
Year: 2006
Journal: Bioinformatics
Title: A novel domain suggests a ciliary function for ASPM, a brain size determining gene.
Volume: 22
Issue: 9
Pages: 1031-5
Publication  
First Author: Ducharme P
Year: 2018
Journal: Mol Cell Neurosci
Title: The ferroxidase ceruloplasmin influences Reelin processing, cofilin phosphorylation and neuronal organization in the developing brain.
Volume: 92
Pages: 104-113
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Klomp LW
Year: 1996
Journal: J Clin Invest
Title: Ceruloplasmin gene expression in the murine central nervous system.
Volume: 98
Issue: 1
Pages: 207-15
Publication
First Author: Harris ZL
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux.
Volume: 96
Issue: 19
Pages: 10812-7
Publication
First Author: Gray LW
Year: 2009
Journal: Biochem J
Title: Copper proteins and ferroxidases in human plasma and that of wild-type and ceruloplasmin knockout mice.
Volume: 419
Issue: 1
Pages: 237-45
Publication
First Author: Meyer LA
Year: 2001
Journal: J Biol Chem
Title: Copper transport and metabolism are normal in aceruloplasminemic mice.
Volume: 276
Issue: 39
Pages: 36857-61
Publication
First Author: Patel BN
Year: 2002
Journal: J Neurosci
Title: Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury.
Volume: 22
Issue: 15
Pages: 6578-86
Publication
First Author: Zanardi A
Year: 2018
Journal: EMBO Mol Med
Title: Ceruloplasmin replacement therapy ameliorates neurological symptoms in a preclinical model of aceruloplasminemia.
Volume: 10
Issue: 1
Pages: 91-106
Publication      
First Author: Beutler B
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/07/01
Publication
First Author: Baranov VS
Year: 1985
Journal: Genetika
Title: [Mapping of the ceruloplasmin gene on human and laboratory mouse chromosomes by direct in situ hybridization].
Volume: 21
Issue: 3
Pages: 409-19
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1205264
Age: postnatal week 6-8
Image: st96_444.2
Detected: true
Specimen Num: 37
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1205262
Age: postnatal week 6-8
Image: st96_444
Detected: true
Specimen Num: 37
GXD Expression      
Probe: MGI:4837541
Assay Type: Western blot
Annotation Date: 2010-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:4837542
Age: postnatal adult
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1205264
Age: postnatal week 6-8
Image: st96_444.2
Detected: true
Specimen Num: 40
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1205264
Age: postnatal week 6-8
Image: st96_444.2
Detected: true
Specimen Num: 39
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1205262
Age: postnatal week 6-8
Image: st96_444
Detected: true
Specimen Num: 40
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1205262
Age: postnatal week 6-8
Image: st96_444
Detected: true
Specimen Num: 39
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1205264
Age: postnatal week 6-8
Image: st96_444.2
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1205262
Age: postnatal week 6-8
Image: st96_444
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1205264
Age: postnatal week 6-8
Image: st96_444.2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1205262
Age: postnatal week 6-8
Image: st96_444
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:1205264
Age: postnatal week 6-8
Image: st96_444.2
Detected: true
Specimen Num: 34
GXD Expression    
Probe: MGI:1205260
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:1205262
Age: postnatal week 6-8
Image: st96_444
Detected: true
Specimen Num: 34