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Search results 1 to 100 out of 114 for Cpsf6

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0.065s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: CPSF6, also known as CFIm68, is a component of the Cleavage Factor Im complex (CFIm) which plays a key role in pre-mRNA 3'-cleavage and polyadenylation []. It has been shown to bind HIV-1 capsid and connect HIV-1 preintegration complexes to intranuclear trafficking pathways that link integration to transcriptionally active chromatin [].
Gene
Type: gene
Organism: human
Publication
First Author: Ge Y
Year: 2024
Journal: PLoS Pathog
Title: Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
Volume: 20
Issue: 2
Pages: e1012061
Protein
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 552  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 588  
Fragment?: false
Publication
First Author: Sasado T
Year: 2017
Journal: PLoS One
Title: Mutation in cpsf6/CFIm68 (Cleavage and Polyadenylation Specificity Factor Subunit 6) causes short 3'UTRs and disturbs gene expression in developing embryos, as revealed by an analysis of primordial germ cell migration using the medaka mutant naruto.
Volume: 12
Issue: 3
Pages: e0172467
Publication
First Author: Rasheedi S
Year: 2016
Journal: J Biol Chem
Title: The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes.
Volume: 291
Issue: 22
Pages: 11809-19
Publication
First Author: Sartini BL
Year: 2008
Journal: Biol Reprod
Title: Pre-messenger RNA cleavage factor I (CFIm): potential role in alternative polyadenylation during spermatogenesis.
Volume: 78
Issue: 3
Pages: 472-82
Publication
First Author: Li N
Year: 2023
Journal: Stem Cell Reports
Title: CFIm-mediated alternative polyadenylation safeguards the development of mammalian pre-implantation embryos.
Volume: 18
Issue: 1
Pages: 81-96
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:7451081
Assay Type: RT-PCR
Annotation Date: 2023-04-06
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:160331
Stage: TS01
Assay Id: MGI:7451116
Age: embryonic day 0.5
Image: 4
Specimen Label: Zygote
Specimen Num: 1
GXD Expression    
Probe: MGI:7451081
Assay Type: RT-PCR
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:7451116
Age: embryonic day 1.0
Image: 4
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7451081
Assay Type: RT-PCR
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:7451116
Age: embryonic day 2.0
Image: 4
Specimen Label: 4-cell
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7451081
Assay Type: RT-PCR
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Stage: TS03
Assay Id: MGI:7451116
Age: embryonic day 2.5
Image: 4
Specimen Label: 8-cell
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7451081
Assay Type: RT-PCR
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Stage: TS03
Assay Id: MGI:7451116
Age: embryonic day 3.0
Image: 4
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7451081
Assay Type: RT-PCR
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Stage: TS04
Assay Id: MGI:7451116
Age: embryonic day 3.5
Image: 4
Specimen Label: Blastocyst
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2344189
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540605
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7451069
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:7451123
Age: embryonic day 2.0
Image: 4D 4-cell
Note: Nuclear expression remained throughout preimplantation. Granules of expression in cytoplasm observed at 4-cell stage.
Specimen Label: 4D 4-cell
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7451069
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Regionally restricted
Stage: TS01
Assay Id: MGI:7451123
Age: embryonic day 0.5
Image: 4D Zygote
Note: Expression both in nucleus and in cytoplasm.
Specimen Label: 4D Zygote
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2344189
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540605
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7451069
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:7451123
Age: embryonic day 2.5
Image: 4D 8-cell
Note: Nuclear expression remained throughout preimplantation. Expression in cytoplasm peaked at 8-cell stage.
Specimen Label: 4D 8-cell
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585620
Age: embryonic day 16.0
Note: Expression was widespread.
Specimen Label: Embryo
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3585620
Age: embryonic day 18.0
Image: E18
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585620
Age: postnatal day 0-1
Image: P0/1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal day 4-5
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1074494
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585620
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7451069
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:7451123
Age: embryonic day 3.5
Image: 4D Blastocyst
Note: Nuclear expression remained throughout preimplantation. Cytoplasmic expression disappeared in blastocyst.
Specimen Label: 4D Blastocyst
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:7451069
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:7451123
Age: embryonic day 3.0
Image: 4D Morula
Note: Nuclear expression remained throughout preimplantation. Expression in cytoplasm declined at morula stage.
Specimen Label: 4D Morula
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2344189
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540605
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7451069
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:7451123
Age: embryonic day 1.0
Image: 4D 2-cell
Note: Expression both in nucleus and in cytoplasm. Nuclear expression became more detectable at 2-cell stage.
Specimen Label: 4D 2-cell
Detected: true
Specimen Num: 2
Publication
First Author: Kasowitz SD
Year: 2018
Journal: PLoS Genet
Title: Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.
Volume: 14
Issue: 5
Pages: e1007412
Publication
First Author: Maggi LB Jr
Year: 2008
Journal: Mol Cell Biol
Title: Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome.
Volume: 28
Issue: 23
Pages: 7050-65
Publication
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations