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Search results 1 to 100 out of 396 for Crb1

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0.052s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: van de Pavert SA
Year: 2007
Journal: Glia
Title: Crb1 is a determinant of retinal apical Müller glia cell features.
Volume: 55
Issue: 14
Pages: 1486-97
Publication  
First Author: Pak JS
Year: 2015
Journal: Mol Vis
Title: The retinal phenotype of Grk1-/- is compromised by a Crb1 rd8 mutation.
Volume: 21
Pages: 1281-94
Publication
First Author: Watanabe T
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Expression of a novel secretory form (Crb1s) of mouse Crumbs homologue Crb1 in skin development.
Volume: 313
Issue: 2
Pages: 263-70
Publication
First Author: Mehalow AK
Year: 2003
Journal: Hum Mol Genet
Title: CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina.
Volume: 12
Issue: 17
Pages: 2179-89
Publication
First Author: Pellissier LP
Year: 2013
Journal: PLoS Genet
Title: Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis.
Volume: 9
Issue: 12
Pages: e1003976
Publication
First Author: van Rossum AG
Year: 2006
Journal: Hum Mol Genet
Title: Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells.
Volume: 15
Issue: 18
Pages: 2659-72
Publication
First Author: Alves CH
Year: 2013
Journal: Hum Mol Genet
Title: Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.
Volume: 22
Issue: 1
Pages: 35-50
Publication
First Author: van de Pavert SA
Year: 2007
Journal: J Neurosci
Title: A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.
Volume: 27
Issue: 3
Pages: 564-73
Publication
First Author: Chen X
Year: 2013
Journal: J Neuropathol Exp Neurol
Title: Rd8 mutation in the Crb1 gene of CD11c-eYFP transgenic reporter mice results in abnormal numbers of CD11c-positive cells in the retina.
Volume: 72
Issue: 8
Pages: 782-90
Publication
First Author: Mattapallil MJ
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes.
Volume: 53
Issue: 6
Pages: 2921-7
Publication  
First Author: Roh H
Year: 2023
Journal: Front Cell Neurosci
Title: Electrically-evoked responses for retinal prostheses are differentially altered depending on ganglion cell types in outer retinal neurodegeneration caused by Crb1 gene mutation.
Volume: 17
Pages: 1115703
Protein
Organism: Mus musculus/domesticus
Length: 844  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 450  
Fragment?: true
Publication
First Author: Ray TA
Year: 2020
Journal: Nat Commun
Title: Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease.
Volume: 11
Issue: 1
Pages: 3328
Publication  
First Author: Concas D
Year: 2017
Journal: F1000Res
Title: A scoring system for the evaluation of the mutated Crb1/rd8-derived retinal lesions in C57BL/6N mice.
Volume: 6
Pages: 404
Publication
First Author: Low BE
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Correction of the Crb1rd8 allele and retinal phenotype in C57BL/6N mice via TALEN-mediated homology-directed repair.
Volume: 55
Issue: 1
Pages: 387-95
Publication
First Author: Quinn PM
Year: 2019
Journal: Hum Mol Genet
Title: Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype.
Volume: 28
Issue: 1
Pages: 105-123
Publication
First Author: Lajko M
Year: 2017
Journal: PLoS One
Title: Photoreceptor oxidative stress in hyperoxia-induced proliferative retinopathy accelerates rd8 degeneration.
Volume: 12
Issue: 7
Pages: e0180384
Publication  
First Author: Schnabolk G
Year: 2014
Journal: Exp Eye Res
Title: A comparative analysis of C57BL/6J and 6N substrains; chemokine/cytokine expression and susceptibility to laser-induced choroidal neovascularization.
Volume: 129
Pages: 18-23
Publication  
First Author: Richard M
Year: 2006
Journal: Hum Mol Genet
Title: Towards understanding CRUMBS function in retinal dystrophies.
Volume: 15 Spec No 2
Pages: R235-43
Publication
First Author: den Hollander AI
Year: 2002
Journal: Mech Dev
Title: Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain.
Volume: 110
Issue: 1-2
Pages: 203-7
Publication  
First Author: Alves CH
Year: 2019
Journal: Int J Mol Sci
Title: CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity.
Volume: 20
Issue: 17
Publication
First Author: Pellissier LP
Year: 2014
Journal: Hum Mol Genet
Title: CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice.
Volume: 23
Issue: 14
Pages: 3759-71
Publication
First Author: Dolón JF
Year: 2018
Journal: Sci Rep
Title: Expression and localization of the polarity protein CRB2 in adult mouse brain: a comparison with the CRB1rd8 mutant mouse model.
Volume: 8
Issue: 1
Pages: 11652
Publication
First Author: Quinn PM
Year: 2018
Journal: Hum Mol Genet
Title: CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function.
Volume: 27
Issue: 18
Pages: 3137-3153
Publication
First Author: Alves CH
Year: 2013
Journal: PLoS One
Title: Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.
Volume: 8
Issue: 12
Pages: e82532
Publication
First Author: Son S
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Crumbs proteins regulate layered retinal vascular development required for vision.
Volume: 521
Issue: 4
Pages: 939-946
Publication
First Author: Luhmann UF
Year: 2015
Journal: Hum Mol Genet
Title: The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors.
Volume: 24
Issue: 1
Pages: 128-41
Publication
First Author: Aleman TS
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Human CRB1-associated retinal degeneration: comparison with the rd8 Crb1-mutant mouse model.
Volume: 52
Issue: 9
Pages: 6898-910
Publication  
First Author: Aredo B
Year: 2015
Journal: J Neuroinflammation
Title: Differences in the distribution, phenotype and gene expression of subretinal microglia/macrophages in C57BL/6N (Crb1 rd8/rd8) versus C57BL6/J (Crb1 wt/wt) mice.
Volume: 12
Pages: 6
Publication
First Author: Greferath U
Year: 2014
Journal: PLoS One
Title: The role of histamine in the retina: studies on the Hdc knockout mouse.
Volume: 9
Issue: 12
Pages: e116025
Publication
First Author: Fischer MD
Year: 2009
Journal: PLoS One
Title: Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography.
Volume: 4
Issue: 10
Pages: e7507
Publication
First Author: Kwon YS
Year: 2020
Journal: Dev Biol
Title: Cytoglobin deficiency potentiates Crb1-mediated retinal degeneration in rd8 mice.
Volume: 458
Issue: 2
Pages: 141-152
Publication
First Author: van de Pavert SA
Year: 2004
Journal: J Cell Sci
Title: Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure.
Volume: 117
Issue: Pt 18
Pages: 4169-77
Publication
First Author: Cho SH
Year: 2019
Journal: Dev Biol
Title: Targeted deletion of Crb1/Crb2 in the optic vesicle models key features of leber congenital amaurosis 8.
Volume: 453
Issue: 2
Pages: 141-154
Publication  
First Author: Badia A
Year: 2021
Journal: Exp Eye Res
Title: Transcriptomics analysis of Ccl2/Cx3cr1/Crb1rd8 deficient mice provides new insights into the pathophysiology of progressive retinal degeneration.
Volume: 203
Pages: 108424
Publication  
First Author: Luhmann UF
Year: 2013
Journal: Exp Eye Res
Title: Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration.
Volume: 107
Pages: 80-7
Publication
First Author: Weatherly SM
Year: 2022
Journal: PLoS Genet
Title: Identification of Arhgef12 and Prkci as genetic modifiers of retinal dysplasia in the Crb1rd8 mouse model.
Volume: 18
Issue: 6
Pages: e1009798
Publication  
First Author: Markand S
Year: 2016
Journal: Exp Eye Res
Title: Mthfr as a modifier of the retinal phenotype of Crb1(rd8/rd8) mice.
Volume: 145
Pages: 164-172
Publication
First Author: Chang B
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Spontaneous Posterior Segment Vascular Disease Phenotype of a Mouse Model, rnv3, Is Dependent on the Crb1rd8 Allele.
Volume: 59
Issue: 12
Pages: 5127-5139
Publication
First Author: Tonelli Gombalová Z
Year: 2020
Journal: J Comp Neurol
Title: Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.
Volume: 528
Issue: 15
Pages: 2523-2550
Publication  
First Author: Sahu B
Year: 2015
Journal: Mol Vis
Title: Presence of rd8 mutation does not alter the ocular phenotype of late-onset retinal degeneration mouse model.
Volume: 21
Pages: 273-84
Publication
First Author: Cho SH
Year: 2012
Journal: Hum Mol Genet
Title: Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis.
Volume: 21
Issue: 12
Pages: 2663-76
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Gosens I
Year: 2008
Journal: Exp Eye Res
Title: Composition and function of the Crumbs protein complex in the mammalian retina.
Volume: 86
Issue: 5
Pages: 713-26
Publication
First Author: Aartsen WM
Year: 2010
Journal: PLoS One
Title: GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors.
Volume: 5
Issue: 8
Pages: e12387
Publication
First Author: Dando SJ
Year: 2016
Journal: Glia
Title: A case of mistaken identity: CD11c-eYFP(+) cells in the normal mouse brain parenchyma and neural retina display the phenotype of microglia, not dendritic cells.
Volume: 64
Issue: 8
Pages: 1331-49
Publication  
First Author: Perkins GA
Year: 2012
Journal: Mol Vis
Title: Bcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: electron microscopy, tomography and oxygen consumption.
Volume: 18
Pages: 3029-48
Publication
First Author: Saul AB
Year: 2017
Journal: Doc Ophthalmol
Title: Detailed electroretinographic findings in rd8 mice.
Volume: 134
Issue: 3
Pages: 195-203
Publication
First Author: Nagai N
Year: 2015
Journal: Am J Pathol
Title: Novel CCR3 Antagonists Are Effective Mono- and Combination Inhibitors of Choroidal Neovascular Growth and Vascular Permeability.
Volume: 185
Issue: 9
Pages: 2534-49
Publication
First Author: Nagai N
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction.
Volume: 55
Issue: 6
Pages: 3709-19
Publication
First Author: Moore BA
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice.
Volume: 59
Issue: 6
Pages: 2252-2261
Publication
First Author: Stojic A
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Murine Autoimmune Optic Neuritis Is Not Phenotypically Altered by the Retinal Degeneration 8 Mutation.
Volume: 58
Issue: 1
Pages: 318-328
Publication
First Author: Parr GR
Year: 1976
Journal: Biochemistry
Title: A kinetic study of the subunit dissociation and reassembly of rabbit muscle phosphofructokinase.
Volume: 15
Issue: 4
Pages: 857-62
GXD Expression      
Probe: MGI:6759780
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6759783
Age: postnatal adult
Specimen Label: spleen
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6759782
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6759784
Age: postnatal adult
Specimen Label: spleen
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:6759780
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6759783
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6759782
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6759784
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6759780
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:6759783
Age: postnatal adult
Specimen Label: eye
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6759782
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:6759784
Age: postnatal adult
Specimen Label: eye
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6192119
Assay Type: RT-PCR
Annotation Date: 2018-08-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6192437
Age: embryonic day 1.0
Image: S1
Specimen Label: 2c
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6759780
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6759783
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6759782
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6759784
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6759780
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6759783
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6759782
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6759784
Age: postnatal adult
Specimen Label: heart
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6192119
Assay Type: RT-PCR
Annotation Date: 2018-08-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6192437
Age: embryonic day 2.0
Image: S1
Specimen Label: 8c
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6759780
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6759783
Age: postnatal adult
Specimen Label: liver
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6759782
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6759784
Age: postnatal adult
Specimen Label: liver
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:6192119
Assay Type: RT-PCR
Annotation Date: 2018-08-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6192437
Age: embryonic day 0.5
Image: S1
Specimen Label: Zy
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6192119
Assay Type: RT-PCR
Annotation Date: 2018-08-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:6192437
Age: embryonic day 3.5
Image: S1
Specimen Label: Bl
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6759780
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6759783
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:6759782
Assay Type: RT-PCR
Annotation Date: 2021-09-17
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6759784
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 11