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Search results 1 to 100 out of 701 for Creb1

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Type Details Score
Gene
1385 | CREB1
Type: gene
Organism: human
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Gene
459901 | CREB1
Type: gene
Organism: chimpanzee
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Gene
607922 | CREB1
Type: gene
Organism: dog, domestic
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Gene
281713 | CREB1
Type: gene
Organism: cattle
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Gene
395099 | CREB1
Type: gene
Organism: chicken
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Gene
708717 | CREB1
Type: gene
Organism: macaque, rhesus
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Gene
407934 | creb1
Type: gene
Organism: frog, western clawed
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Gene
81646 | Creb1
Type: gene
Organism: rat
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Protein Domain
IPR029802 | CREB1
Type: Family
Description: cAMP-responsive element-binding protein 1 (CREB1) is a phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters [, ]. CRE has the sequence 5'-TGACGTCA-3' []. Transcription is stimulated on binding to the CRE of a phosphorylated CREB dimer, which is held together by leucine zippers.CREB1 plays a key role in neural development [, ]. CREB1 signaling pathway can influence mood, addiction, learning and memory by activating an array of proteins [].
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Protein Coding Gene
MGI:88494 | Creb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
11967539 | J:76211
First Author: Mantamadiotis T
Year: 2002
Journal: Nat Genet
Title: Disruption of CREB function in brain leads to neurodegeneration.
Volume: 31
Issue: 1
Pages: 47-54
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Publication
11988169 | J:76363
First Author: Lonze BE
Year: 2002
Journal: Neuron
Title: Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB.
Volume: 34
Issue: 3
Pages: 371-85
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Publication
19666831 | J:174480
First Author: McPherson CS
Year: 2010
Journal: Cereb Cortex
Title: Deletion of CREB1 from the dorsal telencephalon reduces motivational properties of cocaine.
Volume: 20
Issue: 4
Pages: 941-52
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Publication
18724371 | J:141009
First Author: Maekawa Y
Year: 2008
Journal: Nat Immunol
Title: Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.
Volume: 9
Issue: 10
Pages: 1140-7
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Publication
24349008 | J:211156
First Author: Li L
Year: 2013
Journal: PLoS One
Title: The α and Δ isoforms of CREB1 are required to maintain normal pulmonary vascular resistance.
Volume: 8
Issue: 12
Pages: e80637
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Publication
27150575 | J:251794
 
First Author: Antony N
Year: 2016
Journal: Sci Rep
Title: Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms.
Volume: 6
Pages: 25569
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Publication
16537646 | -
First Author: Vankoningsloo S
Year: 2006
Journal: J Cell Sci
Title: CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes.
Volume: 119
Issue: Pt 7
Pages: 1266-82
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Publication
1309910 | -
First Author: Willems L
Year: 1992
Journal: J Virol
Title: A cyclic AMP-responsive DNA-binding protein (CREB2) is a cellular transactivator of the bovine leukemia virus long terminal repeat.
Volume: 66
Issue: 2
Pages: 766-72
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Publication
15982754 | -
First Author: Carlezon WA Jr
Year: 2005
Journal: Trends Neurosci
Title: The many faces of CREB.
Volume: 28
Issue: 8
Pages: 436-45
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Protein
Q01147
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Publication
21598377 | J:278771
First Author: Zubenko GS
Year: 2011
Journal: Am J Med Genet B Neuropsychiatr Genet
Title: Replacement of homologous mouse DNA sequence with pathogenic 6-base human CREB1 promoter sequence creates murine model of major depressive disorder.
Volume: 156B
Issue: 5
Pages: 517-31
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Protein
Q61441
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: false
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Protein
Q61440
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: false
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Protein
Q61442
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
A0A087WRI6
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
Q61443
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: false
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Publication
2521922 | -
First Author: Gonzalez GA
Year: 1989
Journal: Nature
Title: A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence.
Volume: 337
Issue: 6209
Pages: 749-52
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Protein
Q547S9
Organism: Mus musculus/domesticus
Length: 341  
Fragment?: false
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Protein
P70300
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: true
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Protein
Q62347
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: false
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Protein
Q543W0
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Publication
18508077 | J:168885
First Author: Gomez-Duran A
Year: 2008
Journal: J Mol Biol
Title: Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse Ltbp-1 promoter regulates its constitutive expression in a dioxin receptor-dependent manner.
Volume: 380
Issue: 1
Pages: 1-16
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Publication
1826763 | J:76589
First Author: Struthers RS
Year: 1991
Journal: Nature
Title: Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant.
Volume: 350
Issue: 6319
Pages: 622-4
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Publication
14724230 | J:87734
First Author: Fujioka T
Year: 2004
Journal: J Neurosci
Title: Activation of cAMP signaling facilitates the morphological maturation of newborn neurons in adult hippocampus.
Volume: 24
Issue: 2
Pages: 319-28
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Publication
12374787 | J:80716
First Author: Zhang CY
Year: 2002
Journal: J Biol Chem
Title: Impaired proliferation and survival of activated B cells in transgenic mice that express a dominant-negative cAMP-response element-binding protein transcription factor in B cells.
Volume: 277
Issue: 50
Pages: 48359-65
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Publication
11889468 | J:75643
First Author: Kida S
Year: 2002
Journal: Nat Neurosci
Title: CREB required for the stability of new and reactivated fear memories.
Volume: 5
Issue: 4
Pages: 348-55
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Publication
29884780 | J:266388
First Author: Caracciolo L
Year: 2018
Journal: Nat Commun
Title: CREB controls cortical circuit plasticity and functional recovery after stroke.
Volume: 9
Issue: 1
Pages: 2250
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Publication
25970781 | J:301625
First Author: Leone V
Year: 2015
Journal: Oncotarget
Title: Ccdc6 knock-in mice develop thyroid hyperplasia associated to an enhanced CREB1 activity.
Volume: 6
Issue: 17
Pages: 15628-38
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Publication
37267102 | J:338145
First Author: You M
Year: 2023
Journal: Cell Rep
Title: Mettl3-m(6)A-Creb1 forms an intrinsic regulatory axis in maintaining iNKT cell pool and functional differentiation.
Volume: 42
Issue: 6
Pages: 112584
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Publication
15214044 | J:90757
First Author: Baumann S
Year: 2004
Journal: Eur J Immunol
Title: CREB function is required for normal thymic cellularity and post-irradiation recovery.
Volume: 34
Issue: 7
Pages: 1961-71
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Publication
15341801 | J:128870
First Author: Josselyn SA
Year: 2004
Journal: Neurobiol Learn Mem
Title: Inducible repression of CREB function disrupts amygdala-dependent memory.
Volume: 82
Issue: 2
Pages: 159-63
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Publication
18511691 | J:136439
First Author: Chahrour M
Year: 2008
Journal: Science
Title: MeCP2, a key contributor to neurological disease, activates and represses transcription.
Volume: 320
Issue: 5880
Pages: 1224-9
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Publication
20367754 | J:165910
First Author: Parlato R
Year: 2010
Journal: J Neurochem
Title: Effects of the cell type-specific ablation of the cAMP-responsive transcription factor in noradrenergic neurons on locus coeruleus firing and withdrawal behavior after chronic exposure to morphine.
Volume: 115
Issue: 3
Pages: 563-73
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Publication
21209091 | J:170536
First Author: Chiappini F
Year: 2011
Journal: J Biol Chem
Title: Lack of cAMP-response element-binding protein 1 in the hypothalamus causes obesity.
Volume: 286
Issue: 10
Pages: 8094-105
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Publication
12486182 | J:128618
First Author: Newton SS
Year: 2002
Journal: J Neurosci
Title: Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect.
Volume: 22
Issue: 24
Pages: 10883-90
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Publication
27070462 | J:232106
   
First Author: Walia MK
Year: 2016
Journal: Elife
Title: Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.
Volume: 5
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Publication
24642863 | J:215363
First Author: Spieler D
Year: 2014
Journal: Genome Res
Title: Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon.
Volume: 24
Issue: 4
Pages: 592-603
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Publication
38173934 | J:344281
 
First Author: Sponchiado M
Year: 2023
Journal: Front Physiol
Title: Club cell CREB regulates the goblet cell transcriptional network and pro-mucin effects of IL-1B.
Volume: 14
Pages: 1323865
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Publication
17965257 | J:126081
First Author: Jin XL
Year: 2007
Journal: Reproduction
Title: cAMP-responsive element-binding protein expression and regulation in the mouse preimplantation embryo.
Volume: 134
Issue: 5
Pages: 667-75
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Publication
1358811 | J:3009
First Author: Barton CH
Year: 1992
Journal: Genomics
Title: Mapping Creb-1 to chromosome 1 in the mouse.
Volume: 14
Issue: 3
Pages: 790-2
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Publication
10781615 | J:159087
First Author: Edelman DB
Year: 2000
Journal: J Biol Chem
Title: The homeodomain protein Barx2 contains activator and repressor domains and interacts with members of the CREB family.
Volume: 275
Issue: 28
Pages: 21737-45
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Publication
23637738 | J:200565
First Author: Antony N
Year: 2013
Journal: PLoS One
Title: cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells.
Volume: 8
Issue: 4
Pages: e59763
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Publication
12871976 | J:217287
First Author: Luo S
Year: 2003
Journal: J Biol Chem
Title: Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements.
Volume: 278
Issue: 39
Pages: 37375-85
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Publication
25883219 | J:258774
First Author: Mylroie H
Year: 2015
Journal: Cardiovasc Res
Title: PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis.
Volume: 106
Issue: 3
Pages: 509-19
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Publication
25694434 | J:278701
First Author: Shi X
Year: 2015
Journal: J Biol Chem
Title: The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.
Volume: 290
Issue: 15
Pages: 9614-25
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Publication
21408140 | J:171712
First Author: Bird AD
Year: 2011
Journal: PLoS One
Title: cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development.
Volume: 6
Issue: 3
Pages: e17843
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Protein Coding Gene
MGP_CAROLIEiJ_G0014207 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016095 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016033 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0015865 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_88494 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015448 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0015837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0015938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0015941 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0015961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016533 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015235 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027445 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015014 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1532935 | J:50412
First Author: Ruppert S
Year: 1992
Journal: EMBO J
Title: Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes.
Volume: 11
Issue: 4
Pages: 1503-12
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Publication
11970866 | J:75993
First Author: Gau D
Year: 2002
Journal: Neuron
Title: Phosphorylation of CREB Ser142 regulates light-induced phase shifts of the circadian clock.
Volume: 34
Issue: 2
Pages: 245-53
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Publication
19826621 | J:180421
 
First Author: Fasano S
Year: 2009
Journal: Front Behav Neurosci
Title: Inhibition of CREB activity in the dorsal portion of the striatum potentiates behavioral responses to drugs of abuse.
Volume: 3
Pages: 29
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Publication
18077703 | J:130579
First Author: Lopez de Armentia M
Year: 2007
Journal: J Neurosci
Title: cAMP response element-binding protein-mediated gene expression increases the intrinsic excitability of CA1 pyramidal neurons.
Volume: 27
Issue: 50
Pages: 13909-18
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Publication
23197734 | J:193114
First Author: Gruart A
Year: 2012
Journal: J Neurosci
Title: Enhanced cAMP response element-binding protein activity increases neuronal excitability, hippocampal long-term potentiation, and classical eyeblink conditioning in alert behaving mice.
Volume: 32
Issue: 48
Pages: 17431-41
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Publication
16525060 | J:106279
First Author: Pittenger C
Year: 2006
Journal: J Neurosci
Title: Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice.
Volume: 26
Issue: 10
Pages: 2808-13
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Publication
17692820 | J:124258
First Author: Niederberger E
Year: 2007
Journal: Biochem Biophys Res Commun
Title: The impact of CREB and its phosphorylation at Ser142 on inflammatory nociception.
Volume: 362
Issue: 1
Pages: 75-80
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Publication
25505876 | J:242260
 
First Author: Vogt MA
Year: 2014
Journal: Front Behav Neurosci
Title: Inducible forebrain-specific ablation of the transcription factor Creb during adulthood induces anxiety but no spatial/contextual learning deficits.
Volume: 8
Pages: 407
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Publication
27431323 | J:246737
First Author: Kim SH
Year: 2016
Journal: Nucleic Acids Res
Title: Tunable regulation of CREB DNA binding activity couples genotoxic stress response and metabolism.
Volume: 44
Issue: 20
Pages: 9667-9680
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Publication
24595858 | J:210887
First Author: Lee D
Year: 2014
Journal: Diabetologia
Title: The transcription factor CREB has no non-redundant functions in hepatic glucose metabolism in mice.
Volume: 57
Issue: 6
Pages: 1242-8
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Publication
34171357 | J:307293
First Author: Kim SH
Year: 2021
Journal: J Biol Chem
Title: Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst attenuation of the cyclic AMP response element-binding protein.
Volume: 297
Issue: 1
Pages: 100908
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Publication
8202542 | J:18749
First Author: Hummler E
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.
Volume: 91
Issue: 12
Pages: 5647-51
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Publication
8999994 | J:38651
First Author: Kogan JH
Year: 1997
Journal: Curr Biol
Title: Spaced training induces normal long-term memory in CREB mutant mice.
Volume: 7
Issue: 1
Pages: 1-11
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Publication
20495061 | J:185932
First Author: Sekeres MJ
Year: 2010
Journal: Learn Mem
Title: Dorsal hippocampal CREB is both necessary and sufficient for spatial memory.
Volume: 17
Issue: 6
Pages: 280-3
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Publication
10454354 | J:51148
First Author: Gass P
Year: 1998
Journal: Learn Mem
Title: Deficits in memory tasks of mice with CREB mutations depend on gene dosage.
Volume: 5
Issue: 4-5
Pages: 274-88
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Publication
15680959 | J:95568
First Author: Walters CL
Year: 2005
Journal: Brain Res
Title: Alterations in morphine-induced reward, locomotor activity, and thermoregulation in CREB-deficient mice.
Volume: 1032
Issue: 1-2
Pages: 193-9
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Publication
12867515 | J:84481
First Author: Balschun D
Year: 2003
Journal: J Neurosci
Title: Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory?
Volume: 23
Issue: 15
Pages: 6304-14
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Publication
11717377 | J:123425
First Author: Walters CL
Year: 2001
Journal: J Neurosci
Title: Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse.
Volume: 21
Issue: 23
Pages: 9438-44
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Publication
7552295 | J:26212
First Author: Blendy JA
Year: 1995
Journal: Brain Res
Title: Effects of kainic acid induced seizures on immediate early gene expression in mice with a targeted mutation of the CREB gene.
Volume: 681
Issue: 1-2
Pages: 8-14
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Publication
15233759 | J:100343
First Author: Hebda-Bauer EK
Year: 2004
Journal: Eur J Neurosci
Title: CREB deficient mice show inhibition and low activity in novel environments without changes in stress reactivity.
Volume: 20
Issue: 2
Pages: 503-13
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Publication
11918283 | J:113304
First Author: Graves L
Year: 2002
Journal: Hippocampus
Title: Behavioral analysis of CREB alphadelta mutation on a B6/129 F1 hybrid background.
Volume: 12
Issue: 1
Pages: 18-26
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Publication
17634380 | J:123315
First Author: Gur TL
Year: 2007
Journal: J Neurosci
Title: cAMP response element-binding protein deficiency allows for increased neurogenesis and a rapid onset of antidepressant response.
Volume: 27
Issue: 29
Pages: 7860-8
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Publication
10355905 | J:101994
First Author: Glazewski S
Year: 1999
Journal: Cereb Cortex
Title: Impaired experience-dependent plasticity in barrel cortex of mice lacking the alpha and delta isoforms of CREB.
Volume: 9
Issue: 3
Pages: 249-56
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Publication
7923378 | J:20672
First Author: Bourtchuladze R
Year: 1994
Journal: Cell
Title: Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.
Volume: 79
Issue: 1
Pages: 59-68
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Publication
12711709 | J:103027
First Author: Graves LA
Year: 2003
Journal: J Neurophysiol
Title: Genetic evidence for a role of CREB in sustained cortical arousal.
Volume: 90
Issue: 2
Pages: 1152-9
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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