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Search results 1 to 100 out of 122 for Crisp2

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
7180 | CRISP2
Type: gene
Organism: human
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Gene
474932 | CRISP2
Type: gene
Organism: dog, domestic
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Gene
512443 | CRISP2
Type: gene
Organism: cattle
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Gene
422045 | CRISP2
Type: gene
Organism: chicken
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Gene
706747 | CRISP2
Type: gene
Organism: macaque, rhesus
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Gene
360445 | Crisp2
Type: gene
Organism: rat
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Gene
462756 | CRISP2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:98815 | Crisp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30759213 | J:273472
First Author: Lim S
Year: 2019
Journal: Endocrinology
Title: CRISP2 Is a Regulator of Multiple Aspects of Sperm Function and Male Fertility.
Volume: 160
Issue: 4
Pages: 915-924
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Publication
17202389 | J:121287
First Author: Busso D
Year: 2007
Journal: Biol Reprod
Title: Evidence for the involvement of testicular protein CRISP2 in mouse sperm-egg fusion.
Volume: 76
Issue: 4
Pages: 701-8
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Publication
2613236 | J:10248
First Author: Kasahara M
Year: 1989
Journal: Genomics
Title: Cloning and mapping of a testis-specific gene with sequence similarity to a sperm-coating glycoprotein gene.
Volume: 5
Issue: 3
Pages: 527-34
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Publication
26786179 | J:280685
First Author: Brukman NG
Year: 2016
Journal: Mol Hum Reprod
Title: Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: implications for fertility disorders.
Volume: 22
Issue: 4
Pages: 240-51
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Publication
17377140 | J:124176
First Author: Gibbs GM
Year: 2007
Journal: Biol Reprod
Title: Cysteine-rich secretory protein 2 binds to mitogen-activated protein kinase kinase kinase 11 in mouse sperm.
Volume: 77
Issue: 1
Pages: 108-14
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Publication
18502891 | J:137028
First Author: Jamsai D
Year: 2008
Journal: Reproduction
Title: Characterization of gametogenetin 1 (GGN1) and its potential role in male fertility through the interaction with the ion channel regulator, cysteine-rich secretory protein 2 (CRISP2) in the sperm tail.
Volume: 135
Issue: 6
Pages: 751-9
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Protein Coding Gene
MGP_CAROLIEiJ_G0021615 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023718 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023722 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_98815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023462 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023588 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023555 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023669 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023584 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024210 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020607 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022527 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10102277 | J:53890
First Author: Zhou G
Year: 1999
Journal: Invest Ophthalmol Vis Sci
Title: Eye1 and Eye2: gene loci that modulate eye size, lens weight, and retinal area in the mouse.
Volume: 40
Issue: 5
Pages: 817-25
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Publication
3472212 | J:8695
First Author: Kasahara M
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: Random cloning of genes from mouse chromosome 17.
Volume: 84
Issue: 10
Pages: 3325-8
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Publication
9115720 | J:33395
First Author: Foster JA
Year: 1996
Journal: Mol Reprod Dev
Title: Autoantigen 1 of the guinea pig sperm acrosome is the homologue of mouse Tpx-1 and human TPX1 and is a member of the cysteine-rich secretory protein (CRISP) family.
Volume: 44
Issue: 2
Pages: 221-9
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Publication
12459257 | J:80770
First Author: Giese A
Year: 2002
Journal: Gene
Title: Molecular characterization of the equine testis-specific protein 1 (TPX1) and acidic epididymal glycoprotein 2 (AEG2) genes encoding members of the cysteine-rich secretory protein (CRISP) family.
Volume: 299
Issue: 1-2
Pages: 101-9
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Publication
11562501 | J:71831
First Author: Olson JH
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Allurin, a 21-kDa sperm chemoattractant from Xenopus egg jelly, is related to mammalian sperm-binding proteins.
Volume: 98
Issue: 20
Pages: 11205-10
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Publication
34422816 | J:311209
 
First Author: Gaikwad AS
Year: 2021
Journal: Front Cell Dev Biol
Title: CRISPs Function to Boost Sperm Power Output and Motility.
Volume: 9
Pages: 693258
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Publication
2562800 | J:9493
First Author: Kasahara M
Year: 1989
Journal: Immunogenetics
Title: A testis-specific gene Tpx-1 maps between Pgk-2 and Mep-1 on mouse chromosome 17.
Volume: 29
Issue: 1
Pages: 61-3
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Publication
10580147 | J:58757
First Author: Klemme LM
Year: 1999
Journal: Gene
Title: Cloning and characterization of the rat Crisp-1 gene.
Volume: 240
Issue: 2
Pages: 279-88
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Publication
1978716 | J:10826
First Author: Vincek V
Year: 1990
Journal: Immunogenetics
Title: Mapping in the mouse of the region homologous to the rat growth and reproduction complex (grc).
Volume: 32
Issue: 4
Pages: 293-5
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Publication
1638086 | J:1307
First Author: Mizuki N
Year: 1992
Journal: Mamm Genome
Title: The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.
Volume: 3
Issue: 5
Pages: 274-80
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Publication
9428696 | J:44892
First Author: Haendler B
Year: 1997
Journal: Eur J Biochem
Title: Differential androgen regulation of the murine genes for cysteine-rich secretory proteins (CRISP).
Volume: 250
Issue: 2
Pages: 440-6
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Publication
10048974 | J:53683
First Author: Tseng YL
Year: 1999
Journal: Int J Cancer
Title: Sterically stabilized anti-idiotype immunoliposomes improve the therapeutic efficacy of doxorubicin in a murine B-cell lymphoma model.
Volume: 80
Issue: 5
Pages: 723-30
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Publication
33037689 | J:307637
First Author: Curci L
Year: 2020
Journal: FASEB J
Title: Functional redundancy and compensation: Deletion of multiple murine Crisp genes reveals their essential role for male fertility.
Volume: 34
Issue: 12
Pages: 15718-15733
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Publication
- | J:12811
First Author: Vincek V
Year: 1993
Journal: Mouse Genome
Title: Genetic mapping of the mouse t complex distal inversion
Volume: 91
Issue: 2
Pages: 337-38
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Publication
2793207 | J:10054
First Author: Brorson KA
Year: 1989
Journal: Immunogenetics
Title: Analysis of a new class I gene mapping to the Hmt region of the mouse.
Volume: 30
Issue: 4
Pages: 273-83
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Publication
1672293 | J:11045
First Author: Nadeau JH
Year: 1991
Journal: Genomics
Title: Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci.
Volume: 9
Issue: 1
Pages: 78-89
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Publication
2573520 | J:10105
First Author: Richards S
Year: 1989
Journal: EMBO J
Title: Genetic and molecular mapping of the Hmt region of mouse.
Volume: 8
Issue: 12
Pages: 3749-57
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Publication
16458478 | J:114923
First Author: Chan WY
Year: 2006
Journal: Genomics
Title: The complexity of antisense transcription revealed by the study of developing male germ cells.
Volume: 87
Issue: 6
Pages: 681-92
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Publication
2574145 | J:10135
First Author: Vincek V
Year: 1989
Journal: Genomics
Title: Linkage map of mouse chromosome 17: localization of 27 new DNA markers.
Volume: 5
Issue: 4
Pages: 773-86
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
23965306 | J:210719
First Author: Chen HY
Year: 2013
Journal: Nucleic Acids Res
Title: DAZAP1 regulates the splicing of Crem, Crisp2 and Pot1a transcripts.
Volume: 41
Issue: 21
Pages: 9858-69
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Allele
Crisp2<em1Smoc> | MGI:7289148
Name: cysteine-rich secretory protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein Domain
IPR001283 | CRISP-related
Type: Family
Description: The cysteine-rich secretory proteins (Crisp) are predominantly found in the mammalian male reproductive tract as well as in the venom of reptiles. This family includes mammalian testis-specific protein (Tpx-1), also known as cysteine-rich secretory protein 2 (CRISP2) []; venom allergen 5 from vespid wasps and venom allergen 3 from fire ants, which are potent allergens that mediate allergic reactions to stings insects of the Hymenoptera family []; scoloptoxins from Scolopendra dehaani (Thai centipede) []; plant pathogenesis proteins of the PR-1 family [], which are synthesised during pathogen infection or other stress-related responses; allurin, a sperm chemoattractant [], serotriflin [], etc.The precise function of some of these proteins is still unclear. Tpx-1 or CRISP2 may regulate some ion channels' activity and thereby regulate calcium fluxes during sperm capacitation [].This entry also includes several Tabinhibitin proteins and allergen Tab y 5.0101 from horsefly salivary glands [, ]and antigen 5 like allergen Cul n 1 from biting midge salivary glands [].
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Protein Domain
IPR018244 | Allrgn_V5/Tpx1_CS
Type: Conserved_site
Description: The cysteine-rich secretory proteins (Crisp) are predominantly found in the mammalian male reproductive tract as well as in the venom of reptiles. This family includes mammalian testis-specific protein (Tpx-1), also known as cysteine-rich secretory protein 2 (CRISP2) []; venom allergen 5 from vespid wasps and venom allergen 3 from fire ants, which are potent allergens that mediate allergic reactions to stings insects of the Hymenoptera family []; scoloptoxins from Scolopendra dehaani (Thai centipede) []; plant pathogenesis proteins of the PR-1 family [], which are synthesised during pathogen infection or other stress-related responses; allurin, a sperm chemoattractant [], serotriflin [], etc.The precise function of some of these proteins is still unclear. Tpx-1 or CRISP2 may regulate some ion channels' activity and thereby regulate calcium fluxes during sperm capacitation [].This entry also includes allergen Tab y 5.0101 from horsefly salivary glands [].
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Publication
21482758 | J:171346
First Author: Gibbs GM
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Cysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm function.
Volume: 108
Issue: 17
Pages: 7034-9
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Publication
2026137 | -
First Author: Dixon DC
Year: 1991
Journal: EMBO J
Title: Differential targeting of the tobacco PR-1 pathogenesis-related proteins to the extracellular space and vacuoles of crystal idioblasts.
Volume: 10
Issue: 6
Pages: 1317-24
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Publication
18342304 | -
First Author: Burnett LA
Year: 2008
Journal: Dev Biol
Title: Xenopus tropicalis allurin: expression, purification, and characterization of a sperm chemoattractant that exhibits cross-species activity.
Volume: 316
Issue: 2
Pages: 408-16
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Publication
18222185 | -
First Author: Aoki N
Year: 2008
Journal: Biochim Biophys Acta
Title: Serotriflin, a CRISP family protein with binding affinity for small serum protein-2 in snake serum.
Volume: 1784
Issue: 4
Pages: 621-8
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Publication
18571638 | J:139154
First Author: Da Ros VG
Year: 2008
Journal: Dev Biol
Title: Impaired sperm fertilizing ability in mice lacking Cysteine-RIch Secretory Protein 1 (CRISP1).
Volume: 320
Issue: 1
Pages: 12-8
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Publication
20537727 | -
First Author: Schaffartzik A
Year: 2010
Journal: Vet Immunol Immunopathol
Title: Cloning, production and characterization of antigen 5 like proteins from Simulium vittatum and Culicoides nubeculosus, the first cross-reactive allergen associated with equine insect bite hypersensitivity.
Volume: 137
Issue: 1-2
Pages: 76-83
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Publication
19531497 | -
First Author: Ma D
Year: 2009
Journal: Mol Cell Proteomics
Title: Anti-thrombosis repertoire of blood-feeding horsefly salivary glands.
Volume: 8
Issue: 9
Pages: 2071-9
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Publication
23148443 | -
First Author: Liu ZC
Year: 2012
Journal: J Proteome Res
Title: Venomic and transcriptomic analysis of centipede Scolopendra subspinipes dehaani.
Volume: 11
Issue: 12
Pages: 6197-212
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Publication
8454859 | -
First Author: Lu G
Year: 1993
Journal: J Immunol
Title: Sequence analysis and antigenic cross-reactivity of a venom allergen, antigen 5, from hornets, wasps, and yellow jackets.
Volume: 150
Issue: 7
Pages: 2823-30
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Publication
20608917 | -
First Author: Ma D
Year: 2011
Journal: Allergy
Title: Purification and characterization of two new allergens from the salivary glands of the horsefly, Tabanus yao.
Volume: 66
Issue: 1
Pages: 101-9
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Publication
16339766 | -
First Author: Gibbs GM
Year: 2006
Journal: J Biol Chem
Title: The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling.
Volume: 281
Issue: 7
Pages: 4156-63
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Protein
Q9CYL5
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
Q9ET66
Organism: Mus musculus/domesticus
Length: 498  
Fragment?: false
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Protein
Q8BS03
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: false
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Protein
G3UYI2
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
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Protein
A0A0R4J126
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: false
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Protein
D3YVR2
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: true
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Protein
A0A3Q4EC30
Organism: Mus musculus/domesticus
Length: 132  
Fragment?: true
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Protein
A0A3B2W3E6
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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