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Search results 1 to 100 out of 125 for Crisp2

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
7180 | CRISP2
Type: gene
Organism: human
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Gene
360445 | Crisp2
Type: gene
Organism: rat
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Gene
462756 | CRISP2
Type: gene
Organism: chimpanzee
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Gene
474932 | CRISP2
Type: gene
Organism: dog, domestic
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Gene
512443 | CRISP2
Type: gene
Organism: cattle
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Gene
422045 | CRISP2
Type: gene
Organism: chicken
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Gene
706747 | CRISP2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:98815 | Crisp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30759213 | J:273472
First Author: Lim S
Year: 2019
Journal: Endocrinology
Title: CRISP2 Is a Regulator of Multiple Aspects of Sperm Function and Male Fertility.
Volume: 160
Issue: 4
Pages: 915-924
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Publication
17202389 | J:121287
First Author: Busso D
Year: 2007
Journal: Biol Reprod
Title: Evidence for the involvement of testicular protein CRISP2 in mouse sperm-egg fusion.
Volume: 76
Issue: 4
Pages: 701-8
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Publication
2613236 | J:10248
First Author: Kasahara M
Year: 1989
Journal: Genomics
Title: Cloning and mapping of a testis-specific gene with sequence similarity to a sperm-coating glycoprotein gene.
Volume: 5
Issue: 3
Pages: 527-34
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Publication
26786179 | J:280685
First Author: Brukman NG
Year: 2016
Journal: Mol Hum Reprod
Title: Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: implications for fertility disorders.
Volume: 22
Issue: 4
Pages: 240-51
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Publication
18502891 | J:137028
First Author: Jamsai D
Year: 2008
Journal: Reproduction
Title: Characterization of gametogenetin 1 (GGN1) and its potential role in male fertility through the interaction with the ion channel regulator, cysteine-rich secretory protein 2 (CRISP2) in the sperm tail.
Volume: 135
Issue: 6
Pages: 751-9
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Publication
17377140 | J:124176
First Author: Gibbs GM
Year: 2007
Journal: Biol Reprod
Title: Cysteine-rich secretory protein 2 binds to mitogen-activated protein kinase kinase kinase 11 in mouse sperm.
Volume: 77
Issue: 1
Pages: 108-14
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Protein Coding Gene
MGP_CAROLIEiJ_G0021615 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023718 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023722 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_98815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023462 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023588 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023555 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023669 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023584 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024210 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022712 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020607 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022527 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10102277 | J:53890
First Author: Zhou G
Year: 1999
Journal: Invest Ophthalmol Vis Sci
Title: Eye1 and Eye2: gene loci that modulate eye size, lens weight, and retinal area in the mouse.
Volume: 40
Issue: 5
Pages: 817-25
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Publication
3472212 | J:8695
First Author: Kasahara M
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: Random cloning of genes from mouse chromosome 17.
Volume: 84
Issue: 10
Pages: 3325-8
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Publication
9115720 | J:33395
First Author: Foster JA
Year: 1996
Journal: Mol Reprod Dev
Title: Autoantigen 1 of the guinea pig sperm acrosome is the homologue of mouse Tpx-1 and human TPX1 and is a member of the cysteine-rich secretory protein (CRISP) family.
Volume: 44
Issue: 2
Pages: 221-9
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Publication
12459257 | J:80770
First Author: Giese A
Year: 2002
Journal: Gene
Title: Molecular characterization of the equine testis-specific protein 1 (TPX1) and acidic epididymal glycoprotein 2 (AEG2) genes encoding members of the cysteine-rich secretory protein (CRISP) family.
Volume: 299
Issue: 1-2
Pages: 101-9
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Publication
11562501 | J:71831
First Author: Olson JH
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Allurin, a 21-kDa sperm chemoattractant from Xenopus egg jelly, is related to mammalian sperm-binding proteins.
Volume: 98
Issue: 20
Pages: 11205-10
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Publication
2562800 | J:9493
First Author: Kasahara M
Year: 1989
Journal: Immunogenetics
Title: A testis-specific gene Tpx-1 maps between Pgk-2 and Mep-1 on mouse chromosome 17.
Volume: 29
Issue: 1
Pages: 61-3
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Publication
34422816 | J:311209
 
First Author: Gaikwad AS
Year: 2021
Journal: Front Cell Dev Biol
Title: CRISPs Function to Boost Sperm Power Output and Motility.
Volume: 9
Pages: 693258
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Publication
10580147 | J:58757
First Author: Klemme LM
Year: 1999
Journal: Gene
Title: Cloning and characterization of the rat Crisp-1 gene.
Volume: 240
Issue: 2
Pages: 279-88
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Publication
1978716 | J:10826
First Author: Vincek V
Year: 1990
Journal: Immunogenetics
Title: Mapping in the mouse of the region homologous to the rat growth and reproduction complex (grc).
Volume: 32
Issue: 4
Pages: 293-5
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Publication
1638086 | J:1307
First Author: Mizuki N
Year: 1992
Journal: Mamm Genome
Title: The mouse male germ cell-specific gene Tpx-1: molecular structure, mode of expression in spermatogenesis, and sequence similarity to two non-mammalian genes.
Volume: 3
Issue: 5
Pages: 274-80
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Publication
9428696 | J:44892
First Author: Haendler B
Year: 1997
Journal: Eur J Biochem
Title: Differential androgen regulation of the murine genes for cysteine-rich secretory proteins (CRISP).
Volume: 250
Issue: 2
Pages: 440-6
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Publication
10048974 | J:53683
First Author: Tseng YL
Year: 1999
Journal: Int J Cancer
Title: Sterically stabilized anti-idiotype immunoliposomes improve the therapeutic efficacy of doxorubicin in a murine B-cell lymphoma model.
Volume: 80
Issue: 5
Pages: 723-30
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Publication
33037689 | J:307637
First Author: Curci L
Year: 2020
Journal: FASEB J
Title: Functional redundancy and compensation: Deletion of multiple murine Crisp genes reveals their essential role for male fertility.
Volume: 34
Issue: 12
Pages: 15718-15733
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Publication
- | J:12811
First Author: Vincek V
Year: 1993
Journal: Mouse Genome
Title: Genetic mapping of the mouse t complex distal inversion
Volume: 91
Issue: 2
Pages: 337-38
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Publication
2793207 | J:10054
First Author: Brorson KA
Year: 1989
Journal: Immunogenetics
Title: Analysis of a new class I gene mapping to the Hmt region of the mouse.
Volume: 30
Issue: 4
Pages: 273-83
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Publication
1672293 | J:11045
First Author: Nadeau JH
Year: 1991
Journal: Genomics
Title: Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci.
Volume: 9
Issue: 1
Pages: 78-89
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Publication
2573520 | J:10105
First Author: Richards S
Year: 1989
Journal: EMBO J
Title: Genetic and molecular mapping of the Hmt region of mouse.
Volume: 8
Issue: 12
Pages: 3749-57
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Publication
16458478 | J:114923
First Author: Chan WY
Year: 2006
Journal: Genomics
Title: The complexity of antisense transcription revealed by the study of developing male germ cells.
Volume: 87
Issue: 6
Pages: 681-92
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Publication
2574145 | J:10135
First Author: Vincek V
Year: 1989
Journal: Genomics
Title: Linkage map of mouse chromosome 17: localization of 27 new DNA markers.
Volume: 5
Issue: 4
Pages: 773-86
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
23965306 | J:210719
First Author: Chen HY
Year: 2013
Journal: Nucleic Acids Res
Title: DAZAP1 regulates the splicing of Crem, Crisp2 and Pot1a transcripts.
Volume: 41
Issue: 21
Pages: 9858-69
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Allele
Crisp2<em1Smoc> | MGI:7289148
Name: cysteine-rich secretory protein 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7718014 | C57BL/6JSmoc-Crisp2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR001283 | CRISP-related
Type: Family
Description: The cysteine-rich secretory proteins (Crisp) are predominantly found in the mammalian male reproductive tract as well as in the venom of reptiles. This family includes mammalian testis-specific protein (Tpx-1), also known as cysteine-rich secretory protein 2 (CRISP2) []; venom allergen 5 from vespid wasps and venom allergen 3 from fire ants, which are potent allergens that mediate allergic reactions to stings insects of the Hymenoptera family []; scoloptoxins from Scolopendra dehaani (Thai centipede) []; plant pathogenesis proteins of the PR-1 family [], which are synthesised during pathogen infection or other stress-related responses; allurin, a sperm chemoattractant [], serotriflin [], etc.The precise function of some of these proteins is still unclear. Tpx-1 or CRISP2 may regulate some ion channels' activity and thereby regulate calcium fluxes during sperm capacitation [].This entry also includes several Tabinhibitin proteins and allergen Tab y 5.0101 from horsefly salivary glands [, ]and antigen 5 like allergen Cul n 1 from biting midge salivary glands [].
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Protein Domain
IPR018244 | Allrgn_V5/Tpx1_CS
Type: Conserved_site
Description: The cysteine-rich secretory proteins (Crisp) are predominantly found in the mammalian male reproductive tract as well as in the venom of reptiles. This family includes mammalian testis-specific protein (Tpx-1), also known as cysteine-rich secretory protein 2 (CRISP2) []; venom allergen 5 from vespid wasps and venom allergen 3 from fire ants, which are potent allergens that mediate allergic reactions to stings insects of the Hymenoptera family []; scoloptoxins from Scolopendra dehaani (Thai centipede) []; plant pathogenesis proteins of the PR-1 family [], which are synthesised during pathogen infection or other stress-related responses; allurin, a sperm chemoattractant [], serotriflin [], etc.The precise function of some of these proteins is still unclear. Tpx-1 or CRISP2 may regulate some ion channels' activity and thereby regulate calcium fluxes during sperm capacitation [].This entry also includes allergen Tab y 5.0101 from horsefly salivary glands [].
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Publication
21482758 | J:171346
First Author: Gibbs GM
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Cysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm function.
Volume: 108
Issue: 17
Pages: 7034-9
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Publication
2026137 | -
First Author: Dixon DC
Year: 1991
Journal: EMBO J
Title: Differential targeting of the tobacco PR-1 pathogenesis-related proteins to the extracellular space and vacuoles of crystal idioblasts.
Volume: 10
Issue: 6
Pages: 1317-24
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Publication
18342304 | -
First Author: Burnett LA
Year: 2008
Journal: Dev Biol
Title: Xenopus tropicalis allurin: expression, purification, and characterization of a sperm chemoattractant that exhibits cross-species activity.
Volume: 316
Issue: 2
Pages: 408-16
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Publication
18222185 | -
First Author: Aoki N
Year: 2008
Journal: Biochim Biophys Acta
Title: Serotriflin, a CRISP family protein with binding affinity for small serum protein-2 in snake serum.
Volume: 1784
Issue: 4
Pages: 621-8
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Publication
18571638 | J:139154
First Author: Da Ros VG
Year: 2008
Journal: Dev Biol
Title: Impaired sperm fertilizing ability in mice lacking Cysteine-RIch Secretory Protein 1 (CRISP1).
Volume: 320
Issue: 1
Pages: 12-8
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Publication
20537727 | -
First Author: Schaffartzik A
Year: 2010
Journal: Vet Immunol Immunopathol
Title: Cloning, production and characterization of antigen 5 like proteins from Simulium vittatum and Culicoides nubeculosus, the first cross-reactive allergen associated with equine insect bite hypersensitivity.
Volume: 137
Issue: 1-2
Pages: 76-83
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Publication
19531497 | -
First Author: Ma D
Year: 2009
Journal: Mol Cell Proteomics
Title: Anti-thrombosis repertoire of blood-feeding horsefly salivary glands.
Volume: 8
Issue: 9
Pages: 2071-9
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Publication
23148443 | -
First Author: Liu ZC
Year: 2012
Journal: J Proteome Res
Title: Venomic and transcriptomic analysis of centipede Scolopendra subspinipes dehaani.
Volume: 11
Issue: 12
Pages: 6197-212
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Publication
8454859 | -
First Author: Lu G
Year: 1993
Journal: J Immunol
Title: Sequence analysis and antigenic cross-reactivity of a venom allergen, antigen 5, from hornets, wasps, and yellow jackets.
Volume: 150
Issue: 7
Pages: 2823-30
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Publication
20608917 | -
First Author: Ma D
Year: 2011
Journal: Allergy
Title: Purification and characterization of two new allergens from the salivary glands of the horsefly, Tabanus yao.
Volume: 66
Issue: 1
Pages: 101-9
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Publication
16339766 | -
First Author: Gibbs GM
Year: 2006
Journal: J Biol Chem
Title: The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling.
Volume: 281
Issue: 7
Pages: 4156-63
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Protein
Q9CYL5
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: false
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Protein
Q9ET66
Organism: Mus musculus/domesticus
Length: 498  
Fragment?: false
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Protein
Q8BS03
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: false
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Protein
G3UYI2
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
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Protein
A0A0R4J126
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: false
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