|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 127 for Crybb1

<< First    < Previous  |  Next >    Last >>
0.043s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: Beta-crystallin B1 (CRYBB1) is a structural component of the vertebrate eye lens. It may plays a role in promoting higher-order crystallin association in the lens []. Mutations of the CRYBB1 gene have been associated with autosomal recessive nuclear pulverulent cataract [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chan MP
Year: 2008
Journal: Biochemistry
Title: Association properties of betaB1- and betaA3-crystallins: ability to form heterotetramers.
Volume: 47
Issue: 42
Pages: 11062-9
Publication  
First Author: Meyer E
Year: 2009
Journal: Mol Vis
Title: Initiation codon mutation in betaB1-crystallin (CRYBB1) associated with autosomal recessive nuclear pulverulent cataract.
Volume: 15
Pages: 1014-9
Protein
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
Publication
First Author: Limi S
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers.
Volume: 60
Issue: 1
Pages: 234-244
Publication      
First Author: Brioschi S
Year: 2023
Journal: Immunity
Title: A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.
Publication
First Author: Hulsebos TJ
Year: 1995
Journal: Genomics
Title: Assignment of the beta B1 crystallin gene (CRYBB1) to human chromosome 22 and mouse chromosome 5.
Volume: 29
Issue: 3
Pages: 712-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kumar MS
Year: 2009
Journal: FEBS Lett
Title: Disulfide cross-links in the interaction of a cataract-linked alphaA-crystallin mutant with betaB1-crystallin.
Volume: 583
Issue: 1
Pages: 175-9
Publication
First Author: Chen WV
Year: 2001
Journal: Biochim Biophys Acta
Title: The mouse beta B1-crystallin promoter: strict regulation of lens fiber cell specificity.
Volume: 1519
Issue: 1-2
Pages: 30-8
Publication
First Author: Duncan MK
Year: 1996
Journal: Mech Dev
Title: Developmental regulation of the chicken beta B1-crystallin promoter in transgenic mice.
Volume: 57
Issue: 1
Pages: 79-89
Publication
First Author: Stempel D
Year: 2003
Journal: Invest Ophthalmol Vis Sci
Title: BetaB1-crystallin: identification of a candidate ciliary body uveitis antigen.
Volume: 44
Issue: 1
Pages: 203-9
GXD Expression    
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 +/+ 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 -/- 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 +/- 1
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 +/+ 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 -/- 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 +/- 1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 +/+ 1/10
Specimen Num: 2
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 +/+ 1/100
Specimen Num: 3
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 -/- 1/10
Specimen Num: 5
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 -/- 1/100
Specimen Num: 6
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 +/- 1/10
Specimen Num: 8
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2001-09-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:2149582
Age: embryonic day 11.5
Image: 4
Specimen Label: betaB1 E11.5 +/- 1/100
Specimen Num: 9
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 +/+ 1/10
Specimen Num: 2
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 +/+ 1/100
Specimen Num: 3
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 -/- 1/10
Specimen Num: 5
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 -/- 1/100
Specimen Num: 6
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 +/- 1/10
Specimen Num: 8
GXD Expression      
Probe: MGI:2149570
Assay Type: RT-PCR
Annotation Date: 2012-11-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1619825
Stage: TS25
Assay Id: MGI:5444144
Age: embryonic day 17.5
Image: 4
Specimen Label: betaB1 E17.5 +/- 1/100
Specimen Num: 9
GXD Expression    
Probe: MGI:2447315
Assay Type: Northern blot
Annotation Date: 2003-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:2447320
Age: postnatal day 9
Image: 4
Specimen Label: 9 d.p.n. -
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2447315
Assay Type: Northern blot
Annotation Date: 2003-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:2447320
Age: postnatal day 9
Image: 4
Specimen Label: 9 d.p.c. -
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2447315
Assay Type: Northern blot
Annotation Date: 2003-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619824
Stage: TS24
Assay Id: MGI:2447320
Age: embryonic day 16.0
Image: 4
Specimen Label: 16 d.p.c. -
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783823
Stage: TS23
Assay Id: MGI:7423680
Age: embryonic day 15.0
Image: 6
Specimen Label: E15
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783826
Stage: TS26
Assay Id: MGI:7423680
Age: embryonic day 18.0
Image: 6
Specimen Label: E18
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783827
Stage: TS27
Assay Id: MGI:7423680
Age: postnatal day 0
Image: 6
Specimen Label: P0
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783827
Stage: TS27
Assay Id: MGI:7423680
Age: postnatal day 3
Image: 6
Specimen Label: P3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7423680
Age: postnatal day 6
Image: 6
Specimen Label: P6
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7423680
Age: postnatal day 9
Image: 6
Specimen Label: P9
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7423680
Age: postnatal day 12
Image: 6
Specimen Label: P12
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7423680
Age: postnatal day 14
Image: 6
Specimen Label: P14
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7423680
Age: postnatal day 21
Image: 6
Specimen Label: P21
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7423680
Age: postnatal day 28
Image: 6
Specimen Label: P28
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7423680
Age: postnatal day 28
Image: 6
Specimen Label: P42
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:7423675
Assay Type: RT-PCR
Annotation Date: 2023-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783828
Stage: TS28
Assay Id: MGI:7423680
Age: postnatal day 28
Image: 6
Specimen Label: P56
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:7545107
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1783821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7545126
Age: embryonic day 13.5
Image: 7D control
Specimen Label: 7D control
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7545107
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1783821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7545126
Age: embryonic day 13.5
Image: 7D DcKO
Note: Reduced expression compared with the control.
Specimen Label: 7D DcKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2447317
Assay Type: RNA in situ
Annotation Date: 2003-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1784024
Stage: TS24
Assay Id: MGI:2447321
Age: embryonic day 16.5
Image: G,H
Specimen Label: G,H
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:2447317
Assay Type: RNA in situ
Annotation Date: 2003-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1783924
Stage: TS24
Assay Id: MGI:2447321
Age: embryonic day 16.5
Image: G,H
Specimen Label: G,H
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:2447317
Assay Type: RNA in situ
Annotation Date: 2003-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784124
Pattern: Uniform
Stage: TS24
Assay Id: MGI:2447321
Age: embryonic day 16.5
Image: G,H
Specimen Label: G,H
Detected: true
Specimen Num: 1
Publication
First Author: Jiao X
Year: 2016
Journal: PLoS One
Title: A Common Ancestral Mutation in CRYBB3 Identified in Multiple Consanguineous Families with Congenital Cataracts.
Volume: 11
Issue: 6
Pages: e0157005
Publication  
First Author: Terrell AM
Year: 2015
Journal: Exp Eye Res
Title: Molecular characterization of mouse lens epithelial cell lines and their suitability to study RNA granules and cataract associated genes.
Volume: 131
Pages: 42-55
Publication
First Author: Lovicu FJ
Year: 1998
Journal: Development
Title: Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice.
Volume: 125
Issue: 17
Pages: 3365-77
Publication
First Author: Duncan MK
Year: 2004
Journal: Invest Ophthalmol Vis Sci
Title: Ectopic Pax6 expression disturbs lens fiber cell differentiation.
Volume: 45
Issue: 10
Pages: 3589-98
Publication
First Author: Suzuki T
Year: 2002
Journal: Nat Genet
Title: Hermansky-Pudlak syndrome is caused by mutations in HPS4, the human homolog of the mouse light-ear gene.
Volume: 30
Issue: 3
Pages: 321-4
Publication
First Author: Reneker LW
Year: 1996
Journal: Dev Biol
Title: Lens-specific expression of PDGF-A alters lens growth and development.
Volume: 180
Issue: 2
Pages: 554-65
Publication
First Author: Liao X
Year: 1997
Journal: Oncogene
Title: Proviral integrations at the Evi5 locus disrupt a novel 90 kDa protein with homology to the Tre2 oncogene and cell-cycle regulatory proteins.
Volume: 14
Issue: 9
Pages: 1023-9
Publication
First Author: Kerr CL
Year: 2014
Journal: Dev Dyn
Title: AP-2α is required after lens vesicle formation to maintain lens integrity.
Volume: 243
Issue: 10
Pages: 1298-309
Publication
First Author: Yu W
Year: 2019
Journal: Lab Invest
Title: Lens-specific conditional knockout of Msx2 in mice leads to ocular anterior segment dysgenesis via activation of a calcium signaling pathway.
Volume: 99
Issue: 11
Pages: 1714-1727
Publication
First Author: Xie Q
Year: 2016
Journal: J Biol Chem
Title: Regulation of c-Maf and αA-Crystallin in Ocular Lens by Fibroblast Growth Factor Signaling.
Volume: 291
Issue: 8
Pages: 3947-58
Publication
First Author: Dimanlig PV
Year: 2001
Journal: Development
Title: The upstream ectoderm enhancer in Pax6 has an important role in lens induction.
Volume: 128
Issue: 22
Pages: 4415-24
Publication
First Author: Maeda YY
Year: 2001
Journal: Mamm Genome
Title: Two interactive genes responsible for a new inherited cataract (RCT) in the mouse.
Volume: 12
Issue: 4
Pages: 278-83
Publication
First Author: Gonzalez M
Year: 1999
Journal: Neuron
Title: Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions.
Volume: 24
Issue: 3
Pages: 567-83
Publication
First Author: Suzuki-Kerr H
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Forkhead Box Protein P1 Is Dispensable for Retina but Essential for Lens Development.
Volume: 58
Issue: 4
Pages: 1916-1929
Publication
First Author: Min JN
Year: 2004
Journal: Genesis
Title: Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation.
Volume: 40
Issue: 4
Pages: 205-17
Publication
First Author: Xie Q
Year: 2011
Journal: J Biol Chem
Title: The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.
Volume: 286
Issue: 50
Pages: 43259-71
Publication
First Author: Ring BZ
Year: 2000
Journal: Development
Title: Regulation of mouse lens fiber cell development and differentiation by the Maf gene.
Volume: 127
Issue: 2
Pages: 307-17
Publication
First Author: Logan CM
Year: 2017
Journal: Dev Biol
Title: N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.
Volume: 428
Issue: 1
Pages: 118-134
Publication
First Author: Wigle JT
Year: 1999
Journal: Nat Genet
Title: Prox1 function is crucial for mouse lens-fibre elongation.
Volume: 21
Issue: 3
Pages: 318-22
Publication
First Author: Maeda A
Year: 2009
Journal: Dev Dyn
Title: Transcription factor GATA-3 is essential for lens development.
Volume: 238
Issue: 9
Pages: 2280-91