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Search results 1 to 100 out of 458 for Ctbp2

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0.062s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:6512487
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Pattern: Widespread
Stage: TS25
Assay Id: MGI:6512502
Age: embryonic day 17.0
Image: S3c CtBP2
Note: Widely expression in nucleus of various types of cells.
Specimen Label: S3c CtBP2
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6512487
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-26
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286025
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6512502
Age: embryonic day 17.0
Image: S3c CtBP2
Note: Expression at particularly high levels in lung epithelial cells.
Specimen Label: S3c CtBP2
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6512487
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-26
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286026
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6512502
Age: embryonic day 21.0
Image: 3c CtBP2 E21
Note: Expression at particularly high levels in lung epithelial cells.
Specimen Label: 3c CtBP2 E21
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Punctate
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 14
Image: 5a CtBP2 P14 WT
Note: Expression in pre-synaptic ribbons. Expression in lateral aspect of IHCs.
Specimen Label: 5a CtBP2 P14 WT
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Punctate
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 14
Image: 5a CtBP2 P14 DKO
Note: No difference in expression compared to wild type from apical to basal turns.
Specimen Label: 5a CtBP2 P14 DKO
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Punctate
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 30
Image: 5a CtBP2 P30 DKO
Note: No difference in expression compared to wild type from apical to basal turns.
Specimen Label: 5a CtBP2 P30 DKO
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6512487
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Pattern: Widespread
Stage: TS26
Assay Id: MGI:6512502
Age: embryonic day 18.0
Image: 3c CtBP2 E18
Note: Widely expression in nucleus of various types of cells.
Specimen Label: 3c CtBP2 E18
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6512487
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Pattern: Widespread
Stage: TS26
Assay Id: MGI:6512502
Age: embryonic day 21.0
Image: 3c CtBP2 E21
Note: Widely expression in nucleus of various types of cells.
Specimen Label: 3c CtBP2 E21
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6512487
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-26
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3286026
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6512502
Age: embryonic day 18.0
Image: 3c CtBP2 E18
Note: Expression at particularly high levels in lung epithelial cells.
Specimen Label: 3c CtBP2 E18
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Punctate
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 30
Image: 5a CtBP2 P30 WT
Note: Expression in pre-synaptic ribbons. Expression in lateral aspect of IHCs.
Specimen Label: 5a CtBP2 P30 WT
Detected: true
Specimen Num: 3
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
GXD Expression  
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 14
Image: S4 CtBP2 APEX P14 WT
Specimen Label: S4 CtBP2 APEX P14 WT
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 30
Image: S4 CtBP2 APEX P30 DKO
Specimen Label: S4 CtBP2 APEX P30 DKO
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 30
Image: S4 CtBP2 MID P30 WT
Specimen Label: S4 CtBP2 MID P30 WT
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 14
Image: S4 CtBP2 APEX P14 DKO
Specimen Label: S4 CtBP2 APEX P14 DKO
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 30
Image: S4 CtBP2 APEX P30 WT
Specimen Label: S4 CtBP2 APEX P30 WT
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 14
Image: S4 CtBP2 MID P14 WT
Specimen Label: S4 CtBP2 MID P14 WT
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 14
Image: S4 CtBP2 MID P14 DKO
Specimen Label: S4 CtBP2 MID P14 DKO
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:6251597
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7506982
Age: postnatal day 30
Image: S4 CtBP2 MID P30 DKO
Specimen Label: S4 CtBP2 MID P30 DKO
Detected: true
Specimen Num: 12
Publication
First Author: Sekiya M
Year: 2021
Journal: Nat Commun
Title: The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis.
Volume: 12
Issue: 1
Pages: 6315
Publication
First Author: Bajpe PK
Year: 2013
Journal: Mol Cell Biol
Title: The corepressor CTBP2 is a coactivator of retinoic acid receptor/retinoid X receptor in retinoic acid signaling.
Volume: 33
Issue: 16
Pages: 3343-53
Publication
First Author: Hildebrand JD
Year: 2002
Journal: Mol Cell Biol
Title: Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.
Volume: 22
Issue: 15
Pages: 5296-307
Publication
First Author: Wang H
Year: 2019
Journal: Cell Rep
Title: ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development.
Volume: 27
Issue: 8
Pages: 2335-2353.e6
Publication  
First Author: Karaca E
Year: 2020
Journal: Mol Cell Neurosci
Title: The corepressor CtBP2 is required for proper development of the mouse cerebral cortex.
Volume: 104
Pages: 103481
Publication
First Author: Furusawa T
Year: 1999
Journal: Mol Cell Biol
Title: Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1.
Volume: 19
Issue: 12
Pages: 8581-90
Publication    
First Author: Sekiya M
Year: 2023
Journal: Cell Rep
Title: Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function.
Pages: 112914
Publication
First Author: Kim TW
Year: 2015
Journal: Stem Cells
Title: Ctbp2 Modulates NuRD-Mediated Deacetylation of H3K27 and Facilitates PRC2-Mediated H3K27me3 in Active Embryonic Stem Cell Genes During Exit from Pluripotency.
Volume: 33
Issue: 8
Pages: 2442-55
GXD Expression    
Probe: MGI:6512487
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6512502
Age: postnatal newborn
Specimen Label: +/+ CtBP2 not shown
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6512487
Assay Type: Immunohistochemistry
Annotation Date: 2021-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6512502
Age: postnatal newborn
Note: Expression indistinguishable from wild type.
Specimen Label: -/- CtBP2 not shown
Detected: true
Specimen Num: 5
Publication
First Author: Katsuyama E
Year: 2017
Journal: J Immunol
Title: Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells.
Volume: 198
Issue: 11
Pages: 4268-4276
GXD Expression    
Probe: MGI:6170473
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190063
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ctbp2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6170473
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190063
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ctbp2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6170473
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190063
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ctbp2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6170473
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190063
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ctbp2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6170473
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190063
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ctbp2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6170473
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190063
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ctbp2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6170473
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190063
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ctbp2
Detected: true
Specimen Num: 7
Publication
First Author: Zhang W
Year: 2018
Journal: J Biol Chem
Title: The TEA domain family transcription factor TEAD4 represses murine adipogenesis by recruiting the cofactors VGLL4 and CtBP2 into a transcriptional complex.
Volume: 293
Issue: 44
Pages: 17119-17134
Publication
First Author: Vernochet C
Year: 2009
Journal: Mol Cell Biol
Title: C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists.
Volume: 29
Issue: 17
Pages: 4714-28
Publication
First Author: Katsanis N
Year: 1998
Journal: Genomics
Title: A novel C-terminal binding protein (CTBP2) is closely related to CTBP1, an adenovirus E1A-binding protein, and maps to human chromosome 21q21.3.
Volume: 47
Issue: 2
Pages: 294-9
Publication  
First Author: Shankhwar S
Year: 2022
Journal: Front Mol Neurosci
Title: RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons.
Volume: 15
Pages: 838311
Publication
First Author: Verger A
Year: 2006
Journal: Mol Cell Biol
Title: Mechanisms directing the nuclear localization of the CtBP family proteins.
Volume: 26
Issue: 13
Pages: 4882-94
Publication
First Author: Hübler D
Year: 2012
Journal: PLoS One
Title: Differential spatial expression and subcellular localization of CtBP family members in rodent brain.
Volume: 7
Issue: 6
Pages: e39710
Publication
First Author: Sumner ET
Year: 2017
Journal: Oncogene
Title: Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia.
Volume: 36
Issue: 33
Pages: 4810-4816
Publication
First Author: Liberman LD
Year: 2011
Journal: J Neurosci
Title: Opposing gradients of ribbon size and AMPA receptor expression underlie sensitivity differences among cochlear-nerve/hair-cell synapses.
Volume: 31
Issue: 3
Pages: 801-8
Publication
First Author: Stankovic-Valentin N
Year: 2006
Journal: FEBS J
Title: A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP.
Volume: 273
Issue: 13
Pages: 2879-90
Publication
First Author: Chen X
Year: 2023
Journal: Exp Cell Res
Title: Accumulation of advanced glycation end products promotes atrophic nonunion incidence in mice through a CtBP1/2-dependent mechanism.
Volume: 432
Issue: 1
Pages: 113765
Protein
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Turner J
Year: 1998
Journal: EMBO J
Title: Cloning and characterization of mCtBP2, a co-repressor that associates with basic Krüppel-like factor and other mammalian transcriptional regulators.
Volume: 17
Issue: 17
Pages: 5129-40
Publication
First Author: Maxeiner S
Year: 2016
Journal: EMBO J
Title: How to make a synaptic ribbon: RIBEYE deletion abolishes ribbons in retinal synapses and disrupts neurotransmitter release.
Volume: 35
Issue: 10
Pages: 1098-114
Publication    
First Author: Becker L
Year: 2018
Journal: Elife
Title: The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse.
Volume: 7
Publication  
First Author: Mesnard CS
Year: 2022
Journal: Int J Mol Sci
Title: Eliminating Synaptic Ribbons from Rods and Cones Halves the Releasable Vesicle Pool and Slows Down Replenishment.
Volume: 23
Issue: 12
Publication    
First Author: Grabner CP
Year: 2021
Journal: Elife
Title: The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast synaptic vesicle fusion.
Volume: 10
Publication  
First Author: Dembla M
Year: 2018
Journal: EMBO Mol Med
Title: Early auto-immune targeting of photoreceptor ribbon synapses in mouse models of multiple sclerosis.
Volume: 10
Issue: 11
Publication
First Author: Fairless R
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: ERG Responses in Mice with Deletion of the Synaptic Ribbon Component RIBEYE.
Volume: 61
Issue: 5
Pages: 37
Publication    
First Author: Jean P
Year: 2018
Journal: Elife
Title: The synaptic ribbon is critical for sound encoding at high rates and with temporal precision.
Volume: 7
Publication
First Author: Dembla M
Year: 2014
Journal: J Neurosci
Title: ArfGAP3 is a component of the photoreceptor synaptic ribbon complex and forms an NAD(H)-regulated, redox-sensitive complex with RIBEYE that is important for endocytosis.
Volume: 34
Issue: 15
Pages: 5245-60
Publication
First Author: Nishikata I
Year: 2011
Journal: Oncogene
Title: Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiation.
Volume: 30
Issue: 40
Pages: 4194-207
Publication
First Author: Schmitz F
Year: 2000
Journal: Neuron
Title: RIBEYE, a component of synaptic ribbons: a protein's journey through evolution provides insight into synaptic ribbon function.
Volume: 28
Issue: 3
Pages: 857-72
GXD Expression      
Probe: MGI:1351200
Assay Type: Northern blot
Annotation Date: 2006-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:3623785
Age: embryonic day 9.5
Specimen Label: 9.5 dpc
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1351200
Assay Type: Northern blot
Annotation Date: 2006-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:3623785
Age: embryonic day 10.5
Specimen Label: 10.5 dpc
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1351200
Assay Type: Northern blot
Annotation Date: 2006-06-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:3623785
Age: embryonic day 11.5
Specimen Label: 11.5 dpc
Detected: true
Specimen Num: 3