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Search results 1 to 100 out of 4413 for Ctnnb1

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Type Details Score
Gene
1499 | CTNNB1
Type: gene
Organism: human
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Gene
477032 | CTNNB1
Type: gene
Organism: dog, domestic
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Gene
539003 | CTNNB1
Type: gene
Organism: cattle
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Gene
395964 | CTNNB1
Type: gene
Organism: chicken
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Gene
30265 | ctnnb1
Type: gene
Organism: zebrafish
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Gene
574265 | CTNNB1
Type: gene
Organism: macaque, rhesus
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Gene
549712 | ctnnb1
Type: gene
Organism: frog, western clawed
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Gene
84353 | Ctnnb1
Type: gene
Organism: rat
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Gene
450183 | CTNNB1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:88276 | Ctnnb1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:2449010
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7384545
Age: embryonic day 15.5
Image: 5a Ctnnb1 WT
Note: Expression concentrated at apical surface.
Specimen Label: 5a Ctnnb1 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2449010
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7384545
Age: embryonic day 15.5
Image: 5a Ctnnb1 Fmr1 KO
Note: No difference compared with wild type.
Specimen Label: 5a Ctnnb1 Fmr1 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Ctnnb1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is weak staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is weak staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Ctnnb1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is weak staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is weak staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: There is strong staining in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Ctnnb1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is strong staining in the ventricular zone of the prethalamus and weak staining in the dorsal thalamus.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is strong staining in the ventricular zone of the prethalamus and moderate staining in the dorsal thalamus.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: There is strong staining in the mantle zone of the AVH. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and the anterior and posterior IDs.
Specimen Label: Ctnnb1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is moderate staining in the mantle zone of the AVH. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and the anterior and posterior IDs.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is moderate staining in the mantle zone of the AVH and the VMH nucleus and weak staining in the dorsal and ventral POAs, the DAH and the PH. Staining is either absent or ubiquitous in the mantle zone of the PVH, SCH, DMH and ARH nuclei.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450849
Age: embryonic day 11.5
Image: Ctnnb1 - E11.5
Note: There is strong staining in the ventricular zone of the ganglionic eminences and weak staining in the ventricular zone of the cerebral cortex.
Specimen Label: Ctnnb1 - E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: There is weak staining in the mantle zone of the supramam zone. Staining is either absent or ubiquitous in the mantle zone of the premam and mam zones and the TT.
Specimen Label: Ctnnb1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Ctnnb1 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is weak staining in the mantle zone of the premam, mam and supramam zones.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450849
Age: embryonic day 11.5
Image: Ctnnb1 - E11.5
Note: There is strong staining in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Ctnnb1 - E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: There is strong staining in the VZ of the dorsal and ventral POAs, the PVH nucleus, the AVH and anterior ID and weaking staining in the posterior ID and the ARH nucleus. Staining is either absent or ubiquitous in the VZ of the VMH nucleus.
Specimen Label: Ctnnb1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is strong staining in the ventricular zone of the dorsal and ventral POAs, the PVH and VMH nuclei, the AVH and anterior and posterior IDs and weak staining in the ARH nucleus.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is strong staining in the ventricular zone of the dorsal and ventral POAs, the PVH, DMH, VMH, annd ARH nuclei, the AVH, the DAH and the PH and weak staining in the SCH nucleus.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450849
Age: embryonic day 11.5
Image: Ctnnb1 - E11.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Label: Ctnnb1 - E11.5
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: There is strong staining in the ventricular zone of the cerebral cortex.
Specimen Label: Ctnnb1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is moderate staining in the ventricular zone of the cerebral cortex.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is moderate staining in the ventricular zone of the cerebral cortex.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: There is weak staining in the ventricular zone of the premam and mam zones and the TT. Staining is either absent or ubiquitous in the ventricular zone of the supramam zone.
Specimen Label: Ctnnb1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is strong staining in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is strong staining in the ventricular zone of the premam, mam and supramam zones.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: There is strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
Specimen Label: Ctnnb1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is moderate staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is strong staining in the ventricular zone of the ganglionic eminences and weak staining in the mantle zone of the ganglionic eminences.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450849
Age: embryonic day 11.5
Image: Ctnnb1 - E11.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Label: Ctnnb1 - E11.5
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450849
Age: embryonic day 12.5
Image: Ctnnb1 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Ctnnb1 - E12.5
Specimen Num: 2
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•
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•
GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450849
Age: embryonic day 14.5
Image: Ctnnb1 - E14.5
Note: There is weak staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Specimen Label: Ctnnb1 - E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3584756
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450849
Age: embryonic day 16.5
Image: Ctnnb1 - E16.5
Note: There is moderate staining in the mantle zone of the dorsal thalamus and weak staining in the prethalamus.
Specimen Label: Ctnnb1 - E16.5
Detected: true
Specimen Num: 4
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Publication
27131348 | J:236989
First Author: Dong F
Year: 2016
Journal: Hum Mol Genet
Title: Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects.
Volume: 25
Issue: 13
Pages: 2738-2751
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Publication
22253774 | J:184318
First Author: Boyer A
Year: 2012
Journal: PLoS One
Title: CTNNB1 signaling in sertoli cells downregulates spermatogonial stem cell activity via WNT4.
Volume: 7
Issue: 1
Pages: e29764
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Publication
34015032 | J:312327
First Author: Boyer A
Year: 2021
Journal: PLoS One
Title: Constitutive activation of CTNNB1 results in a loss of spermatogonial stem cell activity in mice.
Volume: 16
Issue: 5
Pages: e0251911
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Publication
30782821 | J:273844
     
First Author: Terakawa J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Ovarian insufficiency and CTNNB1 mutations drive malignant transformation of endometrial hyperplasia with altered PTEN/PI3K activities.
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Publication
33577921 | J:307230
First Author: Liang B
Year: 2021
Journal: J Hepatol
Title: TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis.
Volume: 75
Issue: 1
Pages: 120-131
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Publication
23904126 | J:314892
First Author: Stewart CA
Year: 2013
Journal: Mol Endocrinol
Title: CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development.
Volume: 27
Issue: 9
Pages: 1442-54
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Publication
35915089 | J:339243
First Author: Wang J
Year: 2022
Journal: Cell Discov
Title: A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors.
Volume: 8
Issue: 1
Pages: 74
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Publication
21216847 | J:170659
First Author: Sekine S
Year: 2011
Journal: Carcinogenesis
Title: Hepatomas with activating Ctnnb1 mutations in 'Ctnnb1-deficient' livers: a tricky aspect of a conditional knockout mouse model.
Volume: 32
Issue: 4
Pages: 622-8
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Protein
Q80VE7
Organism: Mus musculus/domesticus
Length: 554  
Fragment?: true
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GXD Expression
GXD Expression
   
Probe: MGI:6170503
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190065
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ctnnb1
Detected: true
Specimen Num: 2
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•
•
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•
GXD Expression
GXD Expression
   
Probe: MGI:6170503
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190065
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ctnnb1
Detected: true
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170503
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190065
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ctnnb1
Detected: true
Specimen Num: 5
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170503
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190065
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ctnnb1
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170503
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190065
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ctnnb1
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170503
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190065
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ctnnb1
Detected: true
Specimen Num: 4
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•
•
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•
GXD Expression
GXD Expression
   
Probe: MGI:6170503
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190065
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ctnnb1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6448440
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607210
Pattern: Not Specified
Stage: TS10
Assay Id: MGI:6448451
Age: embryonic day 7.5
Note: Cytosolic levels of Ctnnb1 rise after mesodermal cells downregulate Cdh1 and traverse the primitive streak.
Specimen Label: 2B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6448440
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607210
Pattern: Regionally restricted
Stage: TS10
Assay Id: MGI:6448451
Age: embryonic day 7.5
Note: Ctnnb1 colocalized with Cdh1 at the cell membrane in the primitive streak of the mutant.
Specimen Label: 2E
Detected: true
Specimen Num: 2
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Publication
9783587 | -
First Author: Roose J
Year: 1998
Journal: Nature
Title: The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors.
Volume: 395
Issue: 6702
Pages: 608-12
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Publication
15765502 | -
First Author: Veien ES
Year: 2005
Journal: Dev Dyn
Title: Expression pattern of zebrafish tcf7 suggests unexplored domains of Wnt/beta-catenin activity.
Volume: 233
Issue: 1
Pages: 233-9
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Protein Domain
IPR013558 | CTNNB1-bd_N
Type: Domain
Description: This region tends to appear at the N terminus of proteins also containing DNA-binding HMG (high mobility group) boxes () and appears to bind the armadillo repeat of CTNNB1 (beta-catenin), forming a stable complex. Signalling by Wnt through TCF/LCF is involved in developmental patterning, induction of neural tissues, cell fate decisions and stem cell differentiation []. Isoforms of HMG T-cell factors lacking the N-terminal CTNNB1-binding domain cannot fulfil their role as transcriptional activators in T-cell differentiation [, ].
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GXD Expression
GXD Expression
   
Probe: MGI:7431511
Assay Type: RT-PCR
Annotation Date: 2023-02-06
Strength: Present
Sex: Male
Emaps: EMAPS:2913822
Stage: TS22
Assay Id: MGI:7431529
Age: embryonic day 14.5
Image: 5
Specimen Label: CTNNB1 flox/flox
Detected: true
Specimen Num: 1
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•
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Publication
9566975 | J:47861
First Author: Wong MH
Year: 1998
Journal: J Cell Biol
Title: Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasis.
Volume: 141
Issue: 3
Pages: 765-77
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Publication
32685004 | J:291705
First Author: Ye G
Year: 2020
Journal: Theranostics
Title: Nuclear MYH9-induced CTNNB1 transcription, targeted by staurosporin, promotes gastric cancer cell anoikis resistance and metastasis.
Volume: 10
Issue: 17
Pages: 7545-7560
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Publication
21652632 | J:183055
First Author: Bikkavilli RK
Year: 2011
Journal: J Cell Sci
Title: Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA.
Volume: 124
Issue: Pt 13
Pages: 2310-20
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•
•
•
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Publication
20332102 | J:159634
First Author: Bikkavilli RK
Year: 2010
Journal: J Cell Sci
Title: Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA.
Volume: 123
Issue: Pt 8
Pages: 1352-62
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•
•
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Publication
28347990 | J:242311
First Author: Pflug T
Year: 2017
Journal: Biol Open
Title: Reduced β-catenin expression affects patterning of bone primordia, but not bone maturation.
Volume: 6
Issue: 5
Pages: 582-588
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Publication
25376241 | J:250490
 
First Author: Murata T
Year: 2014
Journal: Sci Rep
Title: β-CateninC429S mice exhibit sterility consequent to spatiotemporally sustained Wnt signalling in the internal genitalia.
Volume: 4
Pages: 6959
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Publication
21613219 | J:175392
First Author: Kato H
Year: 2011
Journal: J Biol Chem
Title: Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival.
Volume: 286
Issue: 29
Pages: 26003-15
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Publication
21685890 | J:174452
First Author: Lyashenko N
Year: 2011
Journal: Nat Cell Biol
Title: Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation.
Volume: 13
Issue: 7
Pages: 753-61
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Publication
18820693 | J:143334
First Author: Maguschak KA
Year: 2008
Journal: Nat Neurosci
Title: Beta-catenin is required for memory consolidation.
Volume: 11
Issue: 11
Pages: 1319-26
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Publication
27902722 | J:254192
First Author: Engel NW
Year: 2016
Journal: PLoS One
Title: Canonical Wnt Signaling Drives Tumor-Like Lesions from Sox2-Positive Precursors of the Murine Olfactory Epithelium.
Volume: 11
Issue: 11
Pages: e0166690
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•
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•
Publication
26159615 | J:225988
   
First Author: Wu H
Year: 2015
Journal: Elife
Title: Slit2 as a β-catenin/Ctnnb1-dependent retrograde signal for presynaptic differentiation.
Volume: 4
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•
•
•
•
Publication
34758313 | J:320924
First Author: Chen WS
Year: 2021
Journal: Cell Rep
Title: Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment.
Volume: 37
Issue: 6
Pages: 109974
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•
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•
Publication
36122209 | J:329211
First Author: Liu F
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic β-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer.
Volume: 119
Issue: 39
Pages: e2202157119
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•
•
•
Publication
23801632 | J:202272
First Author: Kaveri D
Year: 2013
Journal: Blood
Title: β-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL.
Volume: 122
Issue: 5
Pages: 694-704
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•
•
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•
Publication
31131404 | J:294409
First Author: Wickham RJ
Year: 2019
Journal: Hum Mol Genet
Title: Learning impairments and molecular changes in the brain caused by β-catenin loss.
Volume: 28
Issue: 17
Pages: 2965-2975
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•
•
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Publication
23494738 | J:326892
First Author: Zhang R
Year: 2013
Journal: Int J Biol Sci
Title: Disruption of Wnt/β-catenin signaling in odontoblasts and cementoblasts arrests tooth root development in postnatal mouse teeth.
Volume: 9
Issue: 3
Pages: 228-36
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•
•
•
•
Publication
25483876 | J:232607
First Author: Tamarina NA
Year: 2014
Journal: Islets
Title: Characterization of mice expressing Ins1 gene promoter driven CreERT recombinase for conditional gene deletion in pancreatic β-cells.
Volume: 6
Issue: 1
Pages: e27685
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•
•
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Publication
24443144 | J:213360
First Author: Rivas B
Year: 2014
Journal: Genesis
Title: Normal fertility in male mice with deletion of β-catenin gene in germ cells.
Volume: 52
Issue: 4
Pages: 328-32
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Publication
26538583 | J:239437
First Author: Tran KA
Year: 2016
Journal: Circulation
Title: Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis.
Volume: 133
Issue: 2
Pages: 177-86
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Publication
24874479 | J:213270
First Author: Singh Y
Year: 2014
Journal: Br J Cancer
Title: Genetic ablation of β-catenin inhibits the proliferative phenotype of mouse liver adenomas.
Volume: 111
Issue: 1
Pages: 132-8
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•
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•
Publication
21047994 | J:167630
First Author: Rignall B
Year: 2011
Journal: Carcinogenesis
Title: Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen.
Volume: 32
Issue: 1
Pages: 52-7
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•
•
•
•
Publication
24122933 | J:318235
First Author: Fanti M
Year: 2014
Journal: Hepatology
Title: Tri-iodothyronine induces hepatocyte proliferation by protein kinase A-dependent β-catenin activation in rodents.
Volume: 59
Issue: 6
Pages: 2309-20
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•
•
•
•
Publication
25131582 | J:320827
First Author: Wang H
Year: 2015
Journal: Mol Carcinog
Title: Genetic analysis of colon tumors induced by a dietary carcinogen PhIP in CYP1A humanized mice: Identification of mutation of β-catenin/Ctnnb1 as the driver gene for the carcinogenesis.
Volume: 54
Issue: 11
Pages: 1264-74
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•
•
•
•
Publication
32820720 | J:294998
   
First Author: Zhao X
Year: 2020
Journal: Elife
Title: β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells.
Volume: 9
•
•
•
•
•
Publication
27246714 | J:232771
First Author: Messerschmidt D
Year: 2016
Journal: Development
Title: β-catenin-mediated adhesion is required for successful preimplantation mouse embryo development.
Volume: 143
Issue: 11
Pages: 1993-9
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•
•
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Publication
20960542 | J:166528
First Author: Zacharias AL
Year: 2010
Journal: Dev Dyn
Title: Canonical Wnt/β-catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development.
Volume: 239
Issue: 12
Pages: 3215-25
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•
•
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Publication
30696710 | J:272569
 
First Author: Hou Z
Year: 2019
Journal: Development
Title: Wnt/Fgf crosstalk is required for the specification of basal cells in the mouse trachea.
Volume: 146
Issue: 3
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•
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Publication
19154719 | J:144980
First Author: Phng LK
Year: 2009
Journal: Dev Cell
Title: Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.
Volume: 16
Issue: 1
Pages: 70-82
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•
•
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Publication
20610534 | J:182854
First Author: Fan HY
Year: 2010
Journal: Mol Endocrinol
Title: Beta-catenin (CTNNB1) promotes preovulatory follicular development but represses LH-mediated ovulation and luteinization.
Volume: 24
Issue: 8
Pages: 1529-42
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Publication
34658910 | J:312664
 
First Author: Koch PS
Year: 2021
Journal: Front Physiol
Title: Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation.
Volume: 12
Pages: 722394
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Publication
11867232 | J:75296
First Author: Li Q
Year: 2002
Journal: Gene
Title: Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
Volume: 283
Issue: 1-2
Pages: 255-62
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Publication
29152756 | J:320555
First Author: Liang Y
Year: 2018
Journal: Hepatology
Title: β-catenin deficiency in hepatocytes aggravates hepatocarcinogenesis driven by oncogenic β-catenin and MET.
Volume: 67
Issue: 5
Pages: 1807-1822
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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