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Search results 1 to 100 out of 485 for Ctsl

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Spötter A
Year: 2001
Journal: Cytogenet Cell Genet
Title: Characterization and comparative mapping of the porcine CTSL gene indicates a novel synteny between HSA9q21-->q22 and SSC10q11-->q12.
Volume: 95
Issue: 1-2
Pages: 92-6
Publication
First Author: Petermann I
Year: 2006
Journal: FASEB J
Title: Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice.
Volume: 20
Issue: 8
Pages: 1266-8
Publication
First Author: Reinheckel T
Year: 2005
Journal: J Cell Sci
Title: The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.
Volume: 118
Issue: Pt 15
Pages: 3387-95
Publication
First Author: Xu X
Year: 2016
Journal: PLoS One
Title: Cathepsin L Helps to Defend Mice from Infection with Influenza A.
Volume: 11
Issue: 10
Pages: e0164501
Publication
First Author: Spira D
Year: 2007
Journal: J Biol Chem
Title: Cell type-specific functions of the lysosomal protease cathepsin L in the heart.
Volume: 282
Issue: 51
Pages: 37045-52
Publication
First Author: Xu X
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Cathepsin L protects mice from mycoplasmal infection and is essential for airway lymphangiogenesis.
Volume: 49
Issue: 3
Pages: 437-44
Publication
First Author: Wartmann T
Year: 2010
Journal: Gastroenterology
Title: Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.
Volume: 138
Issue: 2
Pages: 726-37
Publication  
First Author: Xu S
Year: 2018
Journal: Neurobiol Aging
Title: Inhibition of cathepsin L alleviates the microglia-mediated neuroinflammatory responses through caspase-8 and NF-ÎşB pathways.
Volume: 62
Pages: 159-167
Publication
First Author: Tobin DJ
Year: 2002
Journal: Am J Pathol
Title: The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling.
Volume: 160
Issue: 5
Pages: 1807-21
Publication
First Author: Roth W
Year: 2000
Journal: FASEB J
Title: Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling.
Volume: 14
Issue: 13
Pages: 2075-86
Publication
First Author: Dennemärker J
Year: 2010
Journal: Oncogene
Title: Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis.
Volume: 29
Issue: 11
Pages: 1611-21
Publication
First Author: Nakagawa T
Year: 1998
Journal: Science
Title: Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus.
Volume: 280
Issue: 5362
Pages: 450-3
Publication
First Author: Stypmann J
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.
Volume: 99
Issue: 9
Pages: 6234-9
Publication
First Author: Goulet B
Year: 2004
Journal: Mol Cell
Title: A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor.
Volume: 14
Issue: 2
Pages: 207-19
Publication
First Author: Garsen M
Year: 2016
Journal: Kidney Int
Title: Cathepsin L is crucial for the development of early experimental diabetic nephropathy.
Volume: 90
Issue: 5
Pages: 1012-1022
Publication
First Author: Funkelstein L
Year: 2008
Journal: J Biol Chem
Title: Major role of cathepsin L for producing the peptide hormones ACTH, beta-endorphin, and alpha-MSH, illustrated by protease gene knockout and expression.
Volume: 283
Issue: 51
Pages: 35652-9
Publication
First Author: Nishimura F
Year: 2002
Journal: Am J Pathol
Title: Cathepsin-L, a key molecule in the pathogenesis of drug-induced and I-cell disease-mediated gingival overgrowth: a study with cathepsin-L-deficient mice.
Volume: 161
Issue: 6
Pages: 2047-52
Publication  
First Author: Kim MJ
Year: 2024
Journal: JCI Insight
Title: Inhibition of cysteine protease cathepsin Lincreases the level and activity of lysosomal glucocerebrosidase.
Volume: 9
Issue: 3
Publication
First Author: Sugita S
Year: 2009
Journal: J Immunol
Title: Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.
Volume: 183
Issue: 8
Pages: 5013-22
Publication
First Author: Lo CW
Year: 2019
Journal: Diabetologia
Title: Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L.
Volume: 62
Issue: 5
Pages: 822-834
Publication
First Author: Funkelstein L
Year: 2008
Journal: J Neurochem
Title: Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression.
Volume: 106
Issue: 1
Pages: 384-91
Publication
First Author: Zhu CS
Year: 2023
Journal: Sci Adv
Title: Identification of procathepsin L (pCTS-L)-neutralizing monoclonal antibodies to treat potentially lethal sepsis.
Volume: 9
Issue: 5
Pages: eadf4313
Publication
First Author: Hagemann S
Year: 2004
Journal: Eur J Cell Biol
Title: The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles.
Volume: 83
Issue: 11-12
Pages: 775-80
Publication
First Author: Lin Y
Year: 2019
Journal: BMC Biol
Title: Peripheral cathepsin L inhibition induces fat loss in C. elegans and mice through promoting central serotonin synthesis.
Volume: 17
Issue: 1
Pages: 93
Publication
First Author: Shimada N
Year: 2010
Journal: Am J Pathol
Title: Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization.
Volume: 176
Issue: 5
Pages: 2571-80
Publication
First Author: Sever S
Year: 2007
Journal: J Clin Invest
Title: Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease.
Volume: 117
Issue: 8
Pages: 2095-104
Publication
First Author: Honey K
Year: 2002
Journal: Nat Immunol
Title: Thymocyte expression of cathepsin L is essential for NKT cell development.
Volume: 3
Issue: 11
Pages: 1069-74
Publication
First Author: Sun J
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice.
Volume: 31
Issue: 11
Pages: 2500-8
Publication
First Author: Abboud-Jarrous G
Year: 2008
Journal: J Biol Chem
Title: Cathepsin L is responsible for processing and activation of proheparanase through multiple cleavages of a linker segment.
Volume: 283
Issue: 26
Pages: 18167-76
Publication      
First Author: Russell J
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for patch.
Publication
First Author: Pensa S
Year: 2014
Journal: Cell Death Differ
Title: The PI3K regulatory subunits p55α and p50α regulate cell death in vivo.
Volume: 21
Issue: 9
Pages: 1442-50
Publication  
First Author: Grimm C
Year: 2014
Journal: Nat Commun
Title: High susceptibility to fatty liver disease in two-pore channel 2-deficient mice.
Volume: 5
Pages: 4699
Publication
First Author: Wilson SR
Year: 2009
Journal: J Biol Chem
Title: Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption.
Volume: 284
Issue: 4
Pages: 2584-92
Publication
First Author: Kitamoto S
Year: 2007
Journal: Circulation
Title: Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice.
Volume: 115
Issue: 15
Pages: 2065-75
Publication
First Author: Yang M
Year: 2007
Journal: Nat Cell Biol
Title: Cathepsin L activity controls adipogenesis and glucose tolerance.
Volume: 9
Issue: 8
Pages: 970-7
Publication
First Author: Gonzalez AC
Year: 2018
Journal: Cell Rep
Title: Unconventional Trafficking of Mammalian Phospholipase D3 to Lysosomes.
Volume: 22
Issue: 4
Pages: 1040-1053
Publication
First Author: Roy KC
Year: 2008
Journal: J Immunol
Title: Involvement of secretory and endosomal compartments in presentation of an exogenous self-glycolipid to type II NKT cells.
Volume: 180
Issue: 5
Pages: 2942-50
Publication
First Author: Felbor U
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Neuronal loss and brain atrophy in mice lacking cathepsins B and L.
Volume: 99
Issue: 12
Pages: 7883-8
Publication
First Author: Benavides F
Year: 2006
Journal: J Immunol
Title: The radiation-induced nackt (nkt) allele is a loss-of-function mutation of the mouse cathepsin L gene.
Volume: 176
Issue: 2
Pages: 702-3
Publication
First Author: Steenhuis P
Year: 2012
Journal: Biochim Biophys Acta
Title: Proteolytic cleavage of the disease-related lysosomal membrane glycoprotein CLN7.
Volume: 1822
Issue: 10
Pages: 1617-28
Publication
First Author: Minokadeh A
Year: 2010
Journal: Mol Cell Neurosci
Title: Cathepsin L participates in dynorphin production in brain cortex, illustrated by protease gene knockout and expression.
Volume: 43
Issue: 1
Pages: 98-107
Publication
First Author: Benavides F
Year: 2001
Journal: Immunogenetics
Title: The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (CtsI) gene.
Volume: 53
Issue: 3
Pages: 233-42
Publication
First Author: Lennon-Duménil AM
Year: 2001
Journal: EMBO J
Title: The p41 isoform of invariant chain is a chaperone for cathepsin L.
Volume: 20
Issue: 15
Pages: 4055-64
Publication
First Author: Fiebiger E
Year: 2002
Journal: J Exp Med
Title: Invariant chain controls the activity of extracellular cathepsin L.
Volume: 196
Issue: 9
Pages: 1263-9
Publication
First Author: Friedrichs B
Year: 2003
Journal: J Clin Invest
Title: Thyroid functions of mouse cathepsins B, K, and L.
Volume: 111
Issue: 11
Pages: 1733-45
Publication
First Author: Röcken C
Year: 2006
Journal: J Pathol
Title: Cathepsin protease activity modulates amyloid load in extracerebral amyloidosis.
Volume: 210
Issue: 4
Pages: 478-87
Publication
First Author: Everts V
Year: 2006
Journal: J Bone Miner Res
Title: Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone.
Volume: 21
Issue: 9
Pages: 1399-408
Publication  
First Author: Klibi J
Year: 2020
Journal: Front Immunol
Title: Cortical Thymocytes Along With Their Selecting Ligands Are Required for the Further Thymic Maturation of NKT Cells in Mice.
Volume: 11
Pages: 815
Publication
First Author: Silva-Vilches C
Year: 2017
Journal: PLoS One
Title: Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion.
Volume: 12
Issue: 7
Pages: e0178114
Publication
First Author: Mareninova OA
Year: 2015
Journal: Cell Mol Gastroenterol Hepatol
Title: Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis.
Volume: 1
Issue: 6
Pages: 678-694
Publication
First Author: Nepal RM
Year: 2008
Journal: J Leukoc Biol
Title: DM, but not cathepsin L, is required to control an aerosol infection with Mycobacterium tuberculosis.
Volume: 84
Issue: 4
Pages: 1011-8
Publication
First Author: Sargeant TJ
Year: 2014
Journal: Nat Cell Biol
Title: Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization.
Volume: 16
Issue: 11
Pages: 1057-1068
Publication
First Author: Brindle NR
Year: 2015
Journal: PLoS One
Title: Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer.
Volume: 10
Issue: 4
Pages: e0120348
Publication
First Author: Koike M
Year: 2003
Journal: Mol Cell Neurosci
Title: Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice.
Volume: 22
Issue: 2
Pages: 146-61
Publication
First Author: Hsing LC
Year: 2010
Journal: J Autoimmun
Title: Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse.
Volume: 34
Issue: 2
Pages: 96-104
Publication
First Author: Maehr R
Year: 2005
Journal: J Clin Invest
Title: Cathepsin L is essential for onset of autoimmune diabetes in NOD mice.
Volume: 115
Issue: 10
Pages: 2934-43
Publication
First Author: Urbich C
Year: 2005
Journal: Nat Med
Title: Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
Volume: 11
Issue: 2
Pages: 206-13
Publication
First Author: Benavides F
Year: 2002
Journal: Am J Pathol
Title: Impaired hair follicle morphogenesis and cycling with abnormal epidermal differentiation in nackt mice, a cathepsin L-deficient mutation.
Volume: 161
Issue: 2
Pages: 693-703
Publication
First Author: Sun M
Year: 2011
Journal: Cardiovasc Res
Title: Cathepsin-L contributes to cardiac repair and remodelling post-infarction.
Volume: 89
Issue: 2
Pages: 374-83
Publication  
First Author: Parigiani MA
Year: 2020
Journal: Cancers (Basel)
Title: Conditional Gene Targeting Reveals Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression.
Volume: 12
Issue: 8
Publication
First Author: Lombardi G
Year: 2005
Journal: J Immunol
Title: Cathepsin-L influences the expression of extracellular matrix in lymphoid organs and plays a role in the regulation of thymic output and of peripheral T cell number.
Volume: 174
Issue: 11
Pages: 7022-32
Publication
First Author: Badano MN
Year: 2013
Journal: PLoS One
Title: B-cell lymphopoiesis is regulated by cathepsin L.
Volume: 8
Issue: 4
Pages: e61347
Publication
First Author: Benavides F
Year: 2012
Journal: Mol Carcinog
Title: Protective role of cathepsin L in mouse skin carcinogenesis.
Volume: 51
Issue: 4
Pages: 352-61
Publication
First Author: Gonzalez-Suarez I
Year: 2011
Journal: EMBO J
Title: A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair.
Volume: 30
Issue: 16
Pages: 3383-96
Publication
First Author: McGlinchey RP
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.
Volume: 112
Issue: 30
Pages: 9322-7
Publication
First Author: Tholen M
Year: 2015
Journal: J Biol Chem
Title: Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression.
Volume: 290
Issue: 25
Pages: 15758-15769
Publication
First Author: Tholen S
Year: 2014
Journal: Cell Mol Life Sci
Title: Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis.
Volume: 71
Issue: 5
Pages: 899-916
Publication
First Author: Miller G
Year: 2011
Journal: FASEB J
Title: Asparagine endopeptidase is required for normal kidney physiology and homeostasis.
Volume: 25
Issue: 5
Pages: 1606-17
Publication
First Author: Zeeuwen PL
Year: 2010
Journal: FASEB J
Title: The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea.
Volume: 24
Issue: 10
Pages: 3744-55
Publication
First Author: Henningsson F
Year: 2005
Journal: J Cell Sci
Title: A role for cathepsin E in the processing of mast-cell carboxypeptidase A.
Volume: 118
Issue: Pt 9
Pages: 2035-42
Publication
First Author: Konjar S
Year: 2010
Journal: Immunology
Title: Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L.
Volume: 131
Issue: 2
Pages: 257-67
Publication
First Author: Hämälistö S
Year: 2020
Journal: Nat Commun
Title: Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation.
Volume: 11
Issue: 1
Pages: 229
Publication
First Author: Gocheva V
Year: 2006
Journal: Genes Dev
Title: Distinct roles for cysteine cathepsin genes in multistage tumorigenesis.
Volume: 20
Issue: 5
Pages: 543-56
Publication  
First Author: Tholen M
Year: 2014
Journal: Nat Commun
Title: Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo.
Volume: 5
Pages: 4931
Publication
First Author: Dennemärker J
Year: 2010
Journal: Biol Chem
Title: Impaired turnover of autophagolysosomes in cathepsin L deficiency.
Volume: 391
Issue: 8
Pages: 913-22
Publication
First Author: Orlowski GM
Year: 2017
Journal: J Leukoc Biol
Title: Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation.
Volume: 102
Issue: 1
Pages: 7-17
Publication
First Author: Allan ER
Year: 2015
Journal: PLoS One
Title: Redundancy between Cysteine Cathepsins in Murine Experimental Autoimmune Encephalomyelitis.
Volume: 10
Issue: 6
Pages: e0128945
Publication
First Author: Kalantari P
Year: 2014
Journal: Cell Rep
Title: Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Volume: 6
Issue: 1
Pages: 196-210
Publication
First Author: Honey K
Year: 2002
Journal: J Exp Med
Title: Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands.
Volume: 195
Issue: 10
Pages: 1349-58
Publication
First Author: Maehr R
Year: 2005
Journal: J Immunol
Title: Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice.
Volume: 174
Issue: 11
Pages: 7066-74
Publication
First Author: Shen L
Year: 2004
Journal: Immunity
Title: Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo.
Volume: 21
Issue: 2
Pages: 155-65
Publication
First Author: Gocheva V
Year: 2010
Journal: Genes Dev
Title: IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.
Volume: 24
Issue: 3
Pages: 241-55
Publication
First Author: Prudova A
Year: 2016
Journal: Cell Rep
Title: TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors.
Volume: 16
Issue: 6
Pages: 1762-1773
Publication
First Author: Ohkouchi S
Year: 2013
Journal: PLoS One
Title: Biogenesis and proteolytic processing of lysosomal DNase II.
Volume: 8
Issue: 3
Pages: e59148
Publication
First Author: Zhou X
Year: 2017
Journal: Mol Neurodegener
Title: Lysosomal processing of progranulin.
Volume: 12
Issue: 1
Pages: 62
Publication
First Author: Duewell P
Year: 2010
Journal: Nature
Title: NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Volume: 464
Issue: 7293
Pages: 1357-61
Publication
First Author: Koike M
Year: 2005
Journal: Am J Pathol
Title: Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).
Volume: 167
Issue: 6
Pages: 1713-28
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory