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Search results 1 to 100 out of 287 for Cul3

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: McEvoy JD
Year: 2007
Journal: Mol Cell Biol
Title: Constitutive turnover of cyclin E by Cul3 maintains quiescence.
Volume: 27
Issue: 10
Pages: 3651-66
Publication
First Author: Salinas GD
Year: 2006
Journal: J Biol Chem
Title: Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway.
Volume: 281
Issue: 52
Pages: 40164-73
Publication
First Author: Dong Z
Year: 2020
Journal: Neuron
Title: CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation.
Volume: 105
Issue: 3
Pages: 475-490.e6
Publication
First Author: Morandell J
Year: 2021
Journal: Nat Commun
Title: Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development.
Volume: 12
Issue: 1
Pages: 3058
Publication
First Author: Rapanelli M
Year: 2023
Journal: Transl Psychiatry
Title: Cholinergic neurons in the basal forebrain are involved in behavioral abnormalities associated with Cul3 deficiency: Role of prefrontal cortex projections in cognitive deficits.
Volume: 13
Issue: 1
Pages: 22
Publication
First Author: Huang G
Year: 2017
Journal: J Biol Chem
Title: Squamous cell carcinoma-related oncogene (SCCRO) neddylates Cul3 protein to selectively promote midbody localization and activity of Cul3KLHL21 protein complex during abscission.
Volume: 292
Issue: 37
Pages: 15254-15265
Publication
First Author: He X
Year: 2006
Journal: J Biol Chem
Title: Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.
Volume: 281
Issue: 33
Pages: 23620-31
Publication
First Author: Amar M
Year: 2021
Journal: Mol Psychiatry
Title: Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling.
Volume: 26
Issue: 7
Pages: 3586-3613
Publication    
First Author: Agbor LN
Year: 2019
Journal: JCI Insight
Title: Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension.
Volume: 5
Publication
First Author: Araki Y
Year: 2015
Journal: Biol Open
Title: Generation and analysis of knock-in mice carrying pseudohypoaldosteronism type II-causing mutations in the cullin 3 gene.
Volume: 4
Issue: 11
Pages: 1509-17
Publication
First Author: Abdel Khalek W
Year: 2019
Journal: J Am Soc Nephrol
Title: Severe Arterial Hypertension from Cullin 3 Mutations Is Caused by Both Renal and Vascular Effects.
Volume: 30
Issue: 5
Pages: 811-823
Publication
First Author: Saritas T
Year: 2019
Journal: Sci Rep
Title: Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis.
Volume: 9
Issue: 1
Pages: 4596
Publication
First Author: Schumacher FR
Year: 2015
Journal: EMBO Mol Med
Title: Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia.
Volume: 7
Issue: 10
Pages: 1285-306
Publication
First Author: Agbor LN
Year: 2016
Journal: JCI Insight
Title: Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism.
Volume: 1
Issue: 19
Pages: e91015
Publication  
First Author: Ferdaus MZ
Year: 2017
Journal: JCI Insight
Title: Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects.
Volume: 2
Issue: 24
Publication
First Author: Mathew R
Year: 2012
Journal: Nature
Title: BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.
Volume: 491
Issue: 7425
Pages: 618-21
Publication
First Author: Kossatz U
Year: 2010
Journal: J Clin Invest
Title: The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells.
Volume: 120
Issue: 11
Pages: 3820-33
Publication
First Author: Li X
Year: 2017
Journal: J Exp Med
Title: Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation.
Volume: 214
Issue: 4
Pages: 1093-1109
Publication
First Author: Maeoka Y
Year: 2022
Journal: J Am Soc Nephrol
Title: Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice.
Volume: 33
Issue: 3
Pages: 584-600
Publication
First Author: McCormick JA
Year: 2014
Journal: J Clin Invest
Title: Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3.
Volume: 124
Issue: 11
Pages: 4723-36
Publication
First Author: Mathew R
Year: 2014
Journal: J Exp Med
Title: A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation.
Volume: 211
Issue: 6
Pages: 1137-51
Publication
First Author: Papizan JB
Year: 2018
Journal: J Biol Chem
Title: Cullin-3-RING ubiquitin ligase activity is required for striated muscle function in mice.
Volume: 293
Issue: 23
Pages: 8802-8811
Publication
First Author: Schenková K
Year: 2012
Journal: J Mol Biol
Title: MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a predominantly nuclear dimeric protein.
Volume: 422
Issue: 5
Pages: 659-73
Publication
First Author: Bowlin KM
Year: 2013
Journal: Differentiation
Title: Kbtbd5 is regulated by MyoD and restricted to the myogenic lineage.
Volume: 86
Issue: 4-5
Pages: 184-91
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Jin L
Year: 2012
Journal: Nature
Title: Ubiquitin-dependent regulation of COPII coat size and function.
Volume: 482
Issue: 7386
Pages: 495-500
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Brain
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Heart
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Kidney
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Liver
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Spleen
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Thymus
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Sk. Muscle
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Ovary
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3054420
Assay Type: Western blot
Annotation Date: 2004-10-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3054438
Age: postnatal adult
Image: 2
Specimen Label: Testis
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689418
Stage: TS18
Assay Id: MGI:5688327
Age: embryonic day 11.0
Image: S2
Specimen Label: E11
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:5688327
Age: embryonic day 14.0
Image: S2
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:5688327
Age: embryonic day 17.0
Image: S2
Specimen Label: E17
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5688327
Age: postnatal day 0
Image: S2
Specimen Label: P0
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5688327
Age: postnatal day 2
Image: S2
Specimen Label: P2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5688327
Age: postnatal day 5
Image: S2
Specimen Label: P5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5688327
Age: postnatal day 10
Image: S2
Specimen Label: P10
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5688327
Age: postnatal day 17
Image: S2
Specimen Label: P17
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5688322
Assay Type: Western blot
Annotation Date: 2015-09-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5688327
Age: postnatal adult
Image: S2
Specimen Label: Adult
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3054427
Assay Type: Immunohistochemistry
Annotation Date: 2004-10-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1606511
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:3054441
Age: embryonic day 7.5
Image: 5A +/+
Specimen Label: 5A +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3054427
Assay Type: Immunohistochemistry
Annotation Date: 2004-10-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1606511
Stage: TS11
Assay Id: MGI:3054441
Age: embryonic day 7.5
Image: 5A -/-
Specimen Label: 5A -/-
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:7281821
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7282009
Age: embryonic day 15.5
Image: 10B
Specimen Label: 10B
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3054427
Assay Type: Immunohistochemistry
Annotation Date: 2004-10-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1606611
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:3054441
Age: embryonic day 7.5
Image: 5A +/+
Specimen Label: 5A +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3054427
Assay Type: Immunohistochemistry
Annotation Date: 2004-10-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1606611
Stage: TS11
Assay Id: MGI:3054441
Age: embryonic day 7.5
Image: 5A -/-
Specimen Label: 5A -/-
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:7281821
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7282009
Age: embryonic day 15.5
Image: 10B
Note: Strongest expression is along the ventricular surface.
Specimen Label: 10B
Detected: true
Specimen Num: 1
Publication    
First Author: Levy N
Year: 2000
Journal: GenBank Submission
Title: Mus musculus cullin 3 (Cul3) mRNA, complete cds
Pages: AF129738
Publication
First Author: Tseng LA
Year: 2011
Journal: Mol Cell Neurosci
Title: Interaction of an intracellular pentraxin with a BTB-Kelch protein is associated with ubiquitylation, aggregation and neuronal apoptosis.
Volume: 47
Issue: 4
Pages: 254-64
Publication
First Author: Israeli E
Year: 2016
Journal: Hum Mol Genet
Title: Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.
Volume: 25
Issue: 11
Pages: 2143-2157
Publication  
First Author: Gladwyn-Ng IE
Year: 2015
Journal: Neural Dev
Title: Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex.
Volume: 10
Pages: 9
Publication
First Author: Jin X
Year: 2016
Journal: Cell Rep
Title: The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells.
Volume: 16
Issue: 6
Pages: 1629-1641
Publication
First Author: Meyer SJ
Year: 2020
Journal: J Immunol
Title: Cullin 3 Is Crucial for Pro-B Cell Proliferation, Interacts with CD22, and Controls CD22 Internalization on B Cells.
Volume: 204
Issue: 12
Pages: 3360-3374
Publication    
First Author: Tian M
Year: 2021
Journal: Elife
Title: ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation.
Volume: 10
Publication
First Author: Liu CC
Year: 2016
Journal: Mol Cell
Title: Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.
Volume: 61
Issue: 1
Pages: 84-97
Publication
First Author: Pelham CJ
Year: 2012
Journal: Cell Metab
Title: Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARγ and RhoA/Rho-kinase.
Volume: 16
Issue: 4
Pages: 462-72
Publication
First Author: Sun S
Year: 2019
Journal: Genes Dev
Title: The orphan nuclear receptor SHP regulates ER stress response by inhibiting XBP1s degradation.
Volume: 33
Issue: 15-16
Pages: 1083-1094
Publication
First Author: Singer JD
Year: 1999
Journal: Genes Dev
Title: Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.
Volume: 13
Issue: 18
Pages: 2375-87
Publication
First Author: Bunker JJ
Year: 2015
Journal: Immunity
Title: Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A.
Volume: 43
Issue: 3
Pages: 541-53
Publication
First Author: Lee J
Year: 2012
Journal: J Biol Chem
Title: Autophagy suppresses interleukin-1β (IL-1β) signaling by activation of p62 degradation via lysosomal and proteasomal pathways.
Volume: 287
Issue: 6
Pages: 4033-40
Publication
First Author: Raghavan S
Year: 2018
Journal: J Biol Chem
Title: Protease-activated receptor 1 inhibits cholesterol efflux and promotes atherogenesis via cullin 3-mediated degradation of the ABCA1 transporter.
Volume: 293
Issue: 27
Pages: 10574-10589
Publication
First Author: Claiborn KC
Year: 2010
Journal: J Clin Invest
Title: Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice.
Volume: 120
Issue: 10
Pages: 3713-21
Publication
First Author: Zhang Z
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.
Volume: 113
Issue: 42
Pages: E6418-E6426
Publication
First Author: Matsuki T
Year: 2021
Journal: J Neurosci
Title: STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development.
Volume: 41
Issue: 43
Pages: 8887-8903
Publication
First Author: Boettger-Tong HL
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Identification and sequencing the juvenile spermatogonial depletion critical interval on mouse chromosome 1 reveals the presence of eight candidate genes.
Volume: 288
Issue: 5
Pages: 1129-35
Publication
First Author: Tron AE
Year: 2012
Journal: Mol Cell
Title: The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.
Volume: 46
Issue: 1
Pages: 67-78
Publication
First Author: Miranda-Carboni GA
Year: 2008
Journal: Genes Dev
Title: A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors.
Volume: 22
Issue: 22
Pages: 3121-34
Publication
First Author: Ren K
Year: 2014
Journal: PLoS One
Title: KCTD10 is involved in the cardiovascular system and Notch signaling during early embryonic development.
Volume: 9
Issue: 11
Pages: e112275
Publication      
First Author: Zhang M
Year: 2017
Journal: Genes Dev
Title: Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.
Publication
First Author: Lo JC
Year: 2012
Journal: PLoS Genet
Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
Volume: 8
Issue: 10
Pages: e1002969