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Search results 1 to 98 out of 98 for Cutc

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
51076 | CUTC
Type: gene
Organism: human
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Gene
496655 | cutc
Type: gene
Organism: frog, western clawed
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Gene
361760 | Cutc
Type: gene
Organism: rat
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Gene
477793 | CUTC
Type: gene
Organism: dog, domestic
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Gene
535065 | CUTC
Type: gene
Organism: cattle
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Gene
100614738 | CUTC
Type: gene
Organism: chimpanzee
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Gene
423829 | CUTC
Type: gene
Organism: chicken
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Gene
709050 | CUTC
Type: gene
Organism: macaque, rhesus
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Gene
450025 | cutc
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:1913638 | Cutc
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0022985 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025157 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025102 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024888 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913638 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025571 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025086 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025629 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024102 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024423 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014475 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023906 | -
Type: protein_coding_gene
Organism: Mus spretus
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Protein
Q9D8X1
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
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Protein
Q9D725
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: false
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Protein
F8WHX2
Organism: Mus musculus/domesticus
Length: 262  
Fragment?: false
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Protein
D3YY50
Organism: Mus musculus/domesticus
Length: 254  
Fragment?: true
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
19878721 | -
First Author: Li Y
Year: 2010
Journal: J Struct Biol
Title: Crystal structure of human copper homeostasis protein CutC reveals a potential copper-binding site.
Volume: 169
Issue: 3
Pages: 399-405
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Publication
26660891 | -
First Author: Kunjunni R
Year: 2016
Journal: Biol Trace Elem Res
Title: Silencing of Human CutC Gene (hCutC) Induces Apoptosis in HepG2 Cells.
Volume: 172
Issue: 1
Pages: 120-126
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Gene
735227 | cutc.L
Type: gene
Organism: frog, African clawed
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Protein Domain
IPR005627 | Cu_homeostasis_CutC
Type: Family
Description: Copper homeostasis protein CutC was originally thought to be involved in copper tolerance in Escherichia coli, as mutation in the corresponding gene lead to an increased copper sensitivity []. However, this phenotype has been later reported to depend on the levels of the mRNA-interfering complementary RNA regulator MicL, which is transcribed from a promoter located within the coding sequence of the cutC gene in the enterobacteria []. In the plant pathogen Xylella fastidiosa, this protein has been reported as specific for copper efflux []. The structure of this protein in the bacteria Shigella flexneri showed a monomer structure that adopts a common TIM β/α barrel with 8 β-strands surrounded by 8 α-helices [].The human homologue of this protein, which structure showed a potential copper-binding site, has an important role in intracellular copper homeostasis [, ].
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UniProt Feature
UniProt Feature
Begin: 1
Description: Copper homeostasis protein cutC homolog
Type: chain
End: 272
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Publication
7635807 | -
First Author: Gupta SD
Year: 1995
Journal: J Bacteriol
Title: Identification of cutC and cutF (nlpE) genes involved in copper tolerance in Escherichia coli.
Volume: 177
Issue: 15
Pages: 4207-15
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Allele
Cutc<+> | MGI:3048254
   
Name: cutC copper transporter; wild type
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Allele
Cutc<tm1(KOMP)Vlcg> | MGI:5292871
Name: cutC copper transporter; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Publication
15624211 | -
First Author: Zhu DY
Year: 2005
Journal: Proteins
Title: Crystal structure of the copper homeostasis protein (CutCm) from Shigella flexneri at 1.7 A resolution: the first structure of a new sequence family of TIM barrels.
Volume: 58
Issue: 3
Pages: 764-8
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Publication
25030700 | -
First Author: Guo MS
Year: 2014
Journal: Genes Dev
Title: MicL, a new σE-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein.
Volume: 28
Issue: 14
Pages: 1620-34
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Publication
34616378 | -
 
First Author: Carvalho IGB
Year: 2021
Journal: Front Microbiol
Title: Overexpression of mqsR in Xylella fastidiosa Leads to a Priming Effect of Cells to Copper Stress Tolerance.
Volume: 12
Pages: 712564
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Allele
Cutc<Gt(OST2928)Lex> | MGI:4133005
 
Name: cutC copper transporter; gene trap OST2928, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Cutc<Gt(OST21294)Lex> | MGI:4144496
 
Name: cutC copper transporter; gene trap OST21294, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Cutc<tm1e(EUCOMM)Wtsi> | MGI:4431649
Name: cutC copper transporter; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cutc<tm1a(EUCOMM)Wtsi> | MGI:4432504
Name: cutC copper transporter; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cutc<em8Gpt> | MGI:7297586
Name: cutC copper transporter; endonuclease-mediated mutation 8, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cutc<Gt(IST13019A5)Tigm> | MGI:5156822
 
Name: cutC copper transporter; gene trap IST13019A5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Protein Domain
IPR030905 | CutC_activ_rSAM
Type: Family
Description: A gene cluster responsible for anaerobic choline degradation has been identified within the genome of sulfate-reducing bacteria. The choline utilisation (cut) gene cluster consist of cutC and cutD. Members of this family are CutD, a radical enzyme that serves as an activase for choline TMA-lyase, CutC. CutC is a glycyl radical enzyme related to pyruvate formate-lyase. CutD is related to pyruvate formate-lyase activase [].
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Publication
23151509 | -
First Author: Craciun S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme.
Volume: 109
Issue: 52
Pages: 21307-12
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Protein Domain
IPR036822 | CutC_dom_sf
Type: Homologous_superfamily
Description: Copper homeostasis protein CutC was originally thought to be involved in copper tolerance in Escherichia coli, as mutation in the corresponding gene lead to an increased copper sensitivity []. However, this phenotype has been later reported to depend on the levels of the mRNA-interfering complementary RNA regulator MicL, which is transcribed from a promoter located within the coding sequence of the cutC gene in the enterobacteria []. In the plant pathogen Xylella fastidiosa, this protein has been reported as specific for copper efflux []. The structure of this protein in the bacteria Shigella flexneri showed a monomer structure that adopts a common TIM β/α barrel with 8 β-strands surrounded by 8 α-helices [].The human homologue of this protein, which structure showed a potential copper-binding site, has an important role in intracellular copper homeostasis [, ].
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Publication
24854437 | -
First Author: Craciun S
Year: 2014
Journal: ACS Chem Biol
Title: Characterization of choline trimethylamine-lyase expands the chemistry of glycyl radical enzymes.
Volume: 9
Issue: 7
Pages: 1408-13
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Publication
30718429 | -
First Author: Peck SC
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia.
Volume: 116
Issue: 8
Pages: 3171-3176
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Protein Domain
IPR040074 | BssD/PflA/YjjW
Type: Family
Description: This group of enzymes are activating enzymes (activases) and include:Pyruvate formate-lyase-activating enzyme (PflA, ), which activates pyruvate formate-lyase under anaerobic conditions using S-adenosylmethionine and reduced flavodoxin as cosubstrates [].4-hydroxyphenylacetate decarboxylase activating enzyme (HpdA), which activates 4-hydroxyphenylacetate decarboxylase under anaerobic conditions [].Benzylsuccinate synthase activating enzyme (BssD), which activates benzylsuccinate synthase under anaerobic conditions using S-adenosylmethionine and reduced flavodoxin as cosubstrates [].Choline trimethylamine-lyase activating enzyme (CutD), which activates choline trimethylamine-lyase CutC under anaerobic conditions [].Putative glycyl-radical enzyme activating enzyme YjjW.Trans-4-hydroxy-L-proline dehydratase activating enzyme PflE []. Isethionate sulfite-lyase activating enzyme IslB [].
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Publication
28183913 | -
 
First Author: Levin BJ
Year: 2017
Journal: Science
Title: A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-l-proline.
Volume: 355
Issue: 6325
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Publication
18852451 | -
First Author: Vey JL
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for glycyl radical formation by pyruvate formate-lyase activating enzyme.
Volume: 105
Issue: 42
Pages: 16137-41
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Publication
9632263 | -
First Author: Leuthner B
Year: 1998
Journal: Mol Microbiol
Title: Biochemical and genetic characterization of benzylsuccinate synthase from Thauera aromatica: a new glycyl radical enzyme catalysing the first step in anaerobic toluene metabolism.
Volume: 28
Issue: 3
Pages: 615-28
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Publication
15153112 | -
First Author: Andrei PI
Year: 2004
Journal: Eur J Biochem
Title: Subunit composition of the glycyl radical enzyme p-hydroxyphenylacetate decarboxylase. A small subunit, HpdC, is essential for catalytic activity.
Volume: 271
Issue: 11
Pages: 2225-30
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Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
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Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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