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Search results 1 to 91 out of 91 for Cwc25

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
100145020 | cwc25
Type: gene
Organism: frog, western clawed
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Gene
54883 | CWC25
Type: gene
Organism: human
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Gene
360613 | Cwc25
Type: gene
Organism: rat
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Gene
480536 | CWC25
Type: gene
Organism: dog, domestic
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Gene
454617 | CWC25
Type: gene
Organism: chimpanzee
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Gene
512527 | CWC25
Type: gene
Organism: cattle
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Gene
420000 | CWC25
Type: gene
Organism: chicken
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Gene
406771 | cwc25
Type: gene
Organism: zebrafish
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Gene
695474 | CWC25
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1914730 | Cwc25
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR022209 | CWC25
Type: Family
Description: This domain family is found in eukaryotes, and is approximately 100 amino acids in length. The family is found in association with . There is a single completely conserved residue Y that may be functionally important. Cwc25 has been identified to associate with pre-mRNA splicing factor Cef1/Ntc85, a component of the Prp19-associated complex (NTC) involved in spliceosome activation. Cwc25 is neither tightly associated with NTC nor required for spliceosome activation, but is required for the first catalytic reaction.
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Protein
Q9DBF7
Organism: Mus musculus/domesticus
Length: 416  
Fragment?: false
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Protein
A2A6F5
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0017064 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_AJ_G0019007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018980 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018348 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018873 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018398 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_SPRETEiJ_G0017910 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:510180
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4824126
Age: embryonic day 14.5
Image: euxassay_000128_05
Specimen Label: euxassay_000128_05
Detected: true
Specimen Num: 1
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Protein Coding Gene
MGP_129S1SvImJ_G0019039 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018794 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019433 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018765 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018862 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018120 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018193 | -
Type: protein_coding_gene
Organism: Mus pahari
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GXD Expression
GXD Expression
 
Probe: MGI:510180
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4824126
Age: embryonic day 14.5
Image: euxassay_000128_05
Specimen Label: euxassay_000128_05
Detected: true
Specimen Num: 1
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Protein
Q05CS1
Organism: Mus musculus/domesticus
Length: 371  
Fragment?: true
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Protein
Q9DBF7-2
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: false
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Protein
Q9DBF7-3
Organism: Mus musculus/domesticus
Length: 325  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 1
Description: Pre-mRNA-splicing factor CWC25 homolog
Type: chain
End: 416
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Protein
F7BY36
Organism: Mus musculus/domesticus
Length: 132  
Fragment?: true
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Gene
394402 | cwc25.L
Type: gene
Organism: frog, African clawed
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Gene
446339 | cwc25.S
Type: gene
Organism: frog, African clawed
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Allele
Cwc25<+> | MGI:3610291
 
Name: CWC25 spliceosome-associated protein; wild type
Allele Type: Not Specified
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Allele
Cwc25<tm1(KOMP)Vlcg> | MGI:5051386
Name: CWC25 spliceosome-associated protein; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cwc25<em1(IMPC)J> | MGI:7666143
Name: CWC25 spliceosome-associated protein; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cwc25<Gt(OST194556)Lex> | MGI:4225748
 
Name: CWC25 spliceosome-associated protein; gene trap OST194556, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Cwc25<Gt(EUCE0232d02)Hmgu> | MGI:4371124
 
Name: CWC25 spliceosome-associated protein; gene trap EUCE0232d02, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Cwc25<tm1a(EUCOMM)Wtsi> | MGI:4433107
Name: CWC25 spliceosome-associated protein; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cwc25<tm1e(EUCOMM)Wtsi> | MGI:4433602
Name: CWC25 spliceosome-associated protein; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cwc25<em1Gpt> | MGI:7297590
Name: CWC25 spliceosome-associated protein; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7666144 | C57BL/6NJ-Cwc25<em1(IMPC)J>/Mmjax
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein
Q9DB98
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Publication
15652350 | J:114123
First Author: Maita H
Year: 2005
Journal: Exp Cell Res
Title: CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing.
Volume: 303
Issue: 2
Pages: 375-87
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Publication
14690591 | -
First Author: Hazbun TR
Year: 2003
Journal: Mol Cell
Title: Assigning function to yeast proteins by integration of technologies.
Volume: 12
Issue: 6
Pages: 1353-65
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Protein Domain
IPR019339 | CIR_N_dom
Type: Domain
Description: This entry represents a 45 residue conserved domain found at the N-terminal end CIR protein (CBF1-interacting co-repressor, also known as corepressor interacting with RBPJ 1). This domain can be found in the fungal CWC25 family members and mammlian LENG1 (leukocyte receptor cluster member 1) protein.CBF1 (centromere-binding factor 1) acts as a transcription factor that causes repression by binding specifically to GTGGGAA motifs in responsive promoters, and it requires CIR as a co-repressor. CIR binds to histone deacetylase and to SAP30 and serves as a linker between CBF1 and the histone deacetylase complex []. CIR also plays a role in alternative splicing []. Budding yeast Cwc25 is a pre-mRNA-splicing factor involved in pre-mRNA splicing [].
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Protein
Q9DA19
Organism: Mus musculus/domesticus
Length: 450  
Fragment?: false
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Publication
9874765 | -
First Author: Hsieh JJ
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex.
Volume: 96
Issue: 1
Pages: 23-8
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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