|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 2060 for Cxcl12

<< First    < Previous  |  Next >    Last >>
0.031s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
6387 | CXCL12
Type: gene
Organism: human
•
•
•
•
•
Gene
548481 | cxcl12
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
24772 | Cxcl12
Type: gene
Organism: rat
•
•
•
•
•
Gene
741624 | CXCL12
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
449622 | CXCL12
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
613811 | CXCL12
Type: gene
Organism: cattle
•
•
•
•
•
Gene
395180 | CXCL12
Type: gene
Organism: chicken
•
•
•
•
•
Gene
574334 | CXCL12
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Domain
IPR039813 | CXCL12
Type: Family
Description: CXCL12 (stromal cell-derived factor-1, SDF1) is a chemokine that regulates development in hematopoietic, cardiovascular and nervous systems, and also regulates diverse cell functions, including differentiation, immune synapse formation, proliferation and survival in the immune system []. CXCL12 has two known receptors, CXCR4 and ACKR3/RDC [, ]. Binding of CXCL12 to CXCR4 induces trimeric G protein signaling leading to activation of the Src, phosphoinositide-3 kinase (PI3K)/AKT, ERK, and JNK pathways, contributing to pro-inflammatory function such as protease production and cellular migration [, ].CXCL12 is constitutively expressed in many tissues. It may also be upregulated in the context of infection and inflammation, acting both as a homeostatic and inflammatory chemokine [].
•
•
•
•
•
Protein Coding Gene
MGI:103556 | Cxcl12
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
29398278 | -
 
First Author: Murphy PM
Year: 2018
Journal: Cytokine
Title: Multisystem multitasking by CXCL12 and its receptors CXCR4 and ACKR3.
Volume: 109
Pages: 2-10
•
•
•
•
•
Publication
16107333 | -
First Author: Balabanian K
Year: 2005
Journal: J Biol Chem
Title: The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes.
Volume: 280
Issue: 42
Pages: 35760-6
•
•
•
•
•
Publication
17169327 | -
First Author: Busillo JM
Year: 2007
Journal: Biochim Biophys Acta
Title: Regulation of CXCR4 signaling.
Volume: 1768
Issue: 4
Pages: 952-63
•
•
•
•
•
Publication
12421931 | -
First Author: Vlahakis SR
Year: 2002
Journal: J Immunol
Title: G protein-coupled chemokine receptors induce both survival and apoptotic signaling pathways.
Volume: 169
Issue: 10
Pages: 5546-54
•
•
•
•
•
Publication
8752281 | -
First Author: Oberlin E
Year: 1996
Journal: Nature
Title: The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1.
Volume: 382
Issue: 6594
Pages: 833-5
•
•
•
•
•
Publication
22949334 | -
First Author: Shachar I
Year: 2013
Journal: J Leukoc Biol
Title: The dual roles of inflammatory cytokines and chemokines in the regulation of autoimmune diseases and their clinical implications.
Volume: 93
Issue: 1
Pages: 51-61
•
•
•
•
•
Protein
P40224
Organism: Mus musculus/domesticus
Length: 93  
Fragment?: false
•
•
•
•
•
Protein
H7BX38
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
•
•
•
•
•
Publication
35313337 | J:326031
First Author: Leberzammer J
Year: 2022
Journal: Blood
Title: Targeting platelet-derived CXCL12 impedes arterial thrombosis.
Volume: 139
Issue: 17
Pages: 2691-2705
•
•
•
•
•
Publication
22314082 | J:317844
First Author: Boimel PJ
Year: 2012
Journal: Breast Cancer Res
Title: Contribution of CXCL12 secretion to invasion of breast cancer cells.
Volume: 14
Issue: 1
Pages: R23
•
•
•
•
•
Publication
28132854 | J:240868
First Author: Rezk AF
Year: 2017
Journal: J Invest Dermatol
Title: Misbalanced CXCL12 and CCL5 Chemotactic Signals in Vitiligo Onset and Progression.
Volume: 137
Issue: 5
Pages: 1126-1134
•
•
•
•
•
Publication
32442338 | J:292438
     
First Author: Rajendiran S
Year: 2020
Journal: Stem Cells
Title: Ubiquitous overexpression of CXCL12 confers radiation protection and enhances mobilization of hematopoietic stem and progenitor cells.
•
•
•
•
•
Publication
34433040 | J:310651
First Author: Ridge LA
Year: 2021
Journal: Cell Rep
Title: Dual role for CXCL12 signaling in semilunar valve development.
Volume: 36
Issue: 8
Pages: 109610
•
•
•
•
•
Publication
31533830 | J:292800
First Author: Hardy D
Year: 2019
Journal: Skelet Muscle
Title: Defective angiogenesis in CXCL12 mutant mice impairs skeletal muscle regeneration.
Volume: 9
Issue: 1
Pages: 25
•
•
•
•
•
Publication
26505253 | J:226611
First Author: Hillmer RE
Year: 2015
Journal: Int J Dev Biol
Title: Generation and characterization of mice harboring a conditional CXCL12 allele.
Volume: 59
Issue: 4-6
Pages: 205-9
•
•
•
•
•
Publication
36239312 | J:331053
 
First Author: Chandrasekaran P
Year: 2022
Journal: Development
Title: CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth.
Volume: 149
Issue: 21
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170586
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190075
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Cxcl12
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170586
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190075
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Cxcl12
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170586
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190075
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Cxcl12
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170586
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190075
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Cxcl12
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170586
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190075
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Cxcl12
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170586
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190075
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Cxcl12
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6170586
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190075
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Cxcl12
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
12077273 | J:77238
First Author: Luther SA
Year: 2002
Journal: J Immunol
Title: Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis.
Volume: 169
Issue: 1
Pages: 424-33
•
•
•
•
•
Publication
23434756 | J:193594
First Author: Greenbaum A
Year: 2013
Journal: Nature
Title: CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance.
Volume: 495
Issue: 7440
Pages: 227-30
•
•
•
•
•
Publication
29720724 | J:314996
First Author: Ahirwar DK
Year: 2018
Journal: Oncogene
Title: Fibroblast-derived CXCL12 promotes breast cancer metastasis by facilitating tumor cell intravasation.
Volume: 37
Issue: 32
Pages: 4428-4442
•
•
•
•
•
Publication
36631780 | J:344500
First Author: Wang S
Year: 2023
Journal: J Neuroinflammation
Title: Brain endothelial CXCL12 attracts protective natural killer cells during ischemic stroke.
Volume: 20
Issue: 1
Pages: 8
•
•
•
•
•
Publication
16037394 | J:123937
First Author: Semerad CL
Year: 2005
Journal: Blood
Title: G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow.
Volume: 106
Issue: 9
Pages: 3020-7
•
•
•
•
•
Publication
25833331 | J:224708
First Author: Chen Q
Year: 2015
Journal: Stem Cells
Title: CXCR7 Mediates Neural Progenitor Cells Migration to CXCL12 Independent of CXCR4.
Volume: 33
Issue: 8
Pages: 2574-85
•
•
•
•
•
Publication
18227348 | J:133530
First Author: Bernardini G
Year: 2008
Journal: Blood
Title: CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets.
Volume: 111
Issue: 7
Pages: 3626-34
•
•
•
•
•
Publication
31662443 | J:294765
First Author: Gao JH
Year: 2019
Journal: J Lipid Res
Title: CXCL12 promotes atherosclerosis by downregulating ABCA1 expression via the CXCR4/GSK3β/β-cateninT120/TCF21 pathway.
Volume: 60
Issue: 12
Pages: 2020-2033
•
•
•
•
•
Publication
15626744 | J:98453
First Author: Ara T
Year: 2005
Journal: Blood
Title: The role of CXCL12 in the organ-specific process of artery formation.
Volume: 105
Issue: 8
Pages: 3155-61
•
•
•
•
•
Publication
24747690 | J:217042
First Author: Penzo M
Year: 2014
Journal: Biochim Biophys Acta
Title: Cell migration to CXCL12 requires simultaneous IKKα and IKKβ-dependent NF-κB signaling.
Volume: 1843
Issue: 9
Pages: 1796-1804
•
•
•
•
•
Publication
38095299 | J:344967
 
First Author: Le VH
Year: 2024
Journal: Development
Title: CXCL12 promotes the crossing of retinal ganglion cell axons at the optic chiasm.
Volume: 151
Issue: 2
•
•
•
•
•
Publication
30905620 | J:301425
First Author: Agarwal P
Year: 2019
Journal: Cell Stem Cell
Title: Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.
Volume: 24
Issue: 5
Pages: 769-784.e6
•
•
•
•
•
Publication
31912645 | J:305739
First Author: Chen X
Year: 2020
Journal: J Cell Mol Med
Title: Follicular helper T cells recruit eosinophils into host liver by producing CXCL12 during Schistosoma japonicum infection.
Volume: 24
Issue: 4
Pages: 2566-2572
•
•
•
•
•
Publication
23727298 | J:203016
First Author: Ojeda AF
Year: 2013
Journal: Gene Expr Patterns
Title: Expression of CXCL12 and CXCL14 during eye development in chick and mouse.
Volume: 13
Issue: 8
Pages: 303-10
•
•
•
•
•
Publication
37880234 | J:355364
First Author: Nakatani T
Year: 2023
Journal: Nat Commun
Title: Ebf3(+) niche-derived CXCL12 is required for the localization and maintenance of hematopoietic stem cells.
Volume: 14
Issue: 1
Pages: 6402
•
•
•
•
•
Publication
32319178 | J:294897
First Author: Ankamreddy H
Year: 2020
Journal: Dev Dyn
Title: CXCL12 is required for stirrup-shaped stapes formation during mammalian middle ear development.
Volume: 249
Issue: 9
Pages: 1117-1126
•
•
•
•
•
Publication
39470100 | J:359863
 
First Author: Do LNH
Year: 2024
Journal: Development
Title: A neuro-lymphatic communication guides lymphatic development by CXCL12 and CXCR4 signaling.
Volume: 151
Issue: 22
•
•
•
•
•
Publication
33809663 | J:305633
 
First Author: Pagella P
Year: 2021
Journal: Int J Mol Sci
Title: Distinct Expression Patterns of Cxcl12 in Mesenchymal Stem Cell Niches of Intact and Injured Rodent Teeth.
Volume: 22
Issue: 6
•
•
•
•
•
Publication
16148115 | J:116731
First Author: Honczarenko M
Year: 2005
Journal: J Immunol
Title: Complement C3a enhances CXCL12 (SDF-1)-mediated chemotaxis of bone marrow hematopoietic cells independently of C3a receptor.
Volume: 175
Issue: 6
Pages: 3698-706
•
•
•
•
•
Publication
21990345 | J:177414
First Author: Drury LJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways.
Volume: 108
Issue: 43
Pages: 17655-60
•
•
•
•
•
Publication
22511975 | J:187086
First Author: Bouchery T
Year: 2012
Journal: PLoS One
Title: The chemokine CXCL12 is essential for the clearance of the filaria Litomosoides sigmodontis in resistant mice.
Volume: 7
Issue: 4
Pages: e34971
•
•
•
•
•
Publication
30202007 | J:267594
First Author: Yakulov TA
Year: 2018
Journal: Nat Commun
Title: CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury.
Volume: 9
Issue: 1
Pages: 3660
•
•
•
•
•
Publication
27497284 | J:264478
First Author: Wu PR
Year: 2017
Journal: Cereb Cortex
Title: The Cytokine CXCL12 Promotes Basket Interneuron Inhibitory Synapses in the Medial Prefrontal Cortex.
Volume: 27
Issue: 9
Pages: 4303-4313
•
•
•
•
•
Publication
38678562 | J:348036
First Author: Lee D
Year: 2024
Journal: Cell Rep
Title: Smooth muscle cell-derived Cxcl12 directs macrophage accrual and sympathetic innervation to control thermogenic adipose tissue.
Volume: 43
Issue: 5
Pages: 114169
•
•
•
•
•
Publication
26718114 | J:233163
First Author: Arthur A
Year: 2016
Journal: Stem Cells
Title: Twist-1 Enhances Bone Marrow Mesenchymal Stromal Cell Support of Hematopoiesis by Modulating CXCL12 Expression.
Volume: 34
Issue: 2
Pages: 504-9
•
•
•
•
•
Publication
27251706 | J:308155
First Author: Mühlstedt S
Year: 2016
Journal: J Mol Med (Berl)
Title: Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction.
Volume: 94
Issue: 9
Pages: 1005-14
•
•
•
•
•
Publication
29715476 | J:268109
 
First Author: Liu H
Year: 2018
Journal: Exp Neurol
Title: Epigenetic upregulation of CXCL12 expression contributes to the acquisition and maintenance of morphine-induced conditioned place preference.
Volume: 306
Pages: 55-63
•
•
•
•
•
Publication
17114479 | J:140687
First Author: McCandless EE
Year: 2006
Journal: J Immunol
Title: CXCL12 limits inflammation by localizing mononuclear infiltrates to the perivascular space during experimental autoimmune encephalomyelitis.
Volume: 177
Issue: 11
Pages: 8053-64
•
•
•
•
•
Publication
30865486 | J:289908
First Author: Döring Y
Year: 2019
Journal: Circulation
Title: CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease.
Volume: 139
Issue: 10
Pages: 1338-1340
•
•
•
•
•
Publication
31809740 | J:313385
First Author: Kunz L
Year: 2019
Journal: Cell Stem Cell
Title: A 3D Tissue-wide Digital Imaging Pipeline for Quantitation of Secreted Molecules Shows Absence of CXCL12 Gradients in Bone Marrow.
Volume: 25
Issue: 6
Pages: 846-854.e4
•
•
•
•
•
Publication
23395391 | J:195048
First Author: Li W
Year: 2013
Journal: Dev Cell
Title: Peripheral nerve-derived CXCL12 and VEGF-A regulate the patterning of arterial vessel branching in developing limb skin.
Volume: 24
Issue: 4
Pages: 359-71
•
•
•
•
•
Publication
28418886 | J:274113
First Author: Romain B
Year: 2017
Journal: Oncotarget
Title: Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration.
Volume: 8
Issue: 24
Pages: 38351-38366
•
•
•
•
•
Publication
22956548 | J:200277
First Author: McGinn OJ
Year: 2012
Journal: J Cell Sci
Title: CXCL12 receptor preference, signal transduction, biological response and the expression of 5T4 oncofoetal glycoprotein.
Volume: 125
Issue: Pt 22
Pages: 5467-78
•
•
•
•
•
Publication
28637665 | J:244956
First Author: Dutta A
Year: 2017
Journal: Blood
Title: Hmga2 promotes the development of myelofibrosis in Jak2V617F knockin mice by enhancing TGF-β1 and Cxcl12 pathways.
Volume: 130
Issue: 7
Pages: 920-932
•
•
•
•
•
Publication
24277834 | J:205406
First Author: Feig C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer.
Volume: 110
Issue: 50
Pages: 20212-7
•
•
•
•
•
Publication
22736769 | J:192977
First Author: Hoffmann F
Year: 2012
Journal: J Biol Chem
Title: Rapid uptake and degradation of CXCL12 depend on CXCR7 carboxyl-terminal serine/threonine residues.
Volume: 287
Issue: 34
Pages: 28362-77
•
•
•
•
•
Publication
21690321 | J:178027
First Author: Delano MJ
Year: 2011
Journal: J Immunol
Title: Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.
Volume: 187
Issue: 2
Pages: 911-8
•
•
•
•
•
Publication
24174685 | J:204198
First Author: Memi F
Year: 2013
Journal: J Neurosci
Title: CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability.
Volume: 33
Issue: 44
Pages: 17527-37
•
•
•
•
•
Publication
12444109 | J:80571
First Author: Krug A
Year: 2002
Journal: J Immunol
Title: IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation.
Volume: 169
Issue: 11
Pages: 6079-83
•
•
•
•
•
Publication
38766687 | J:348735
First Author: Jiang G
Year: 2024
Journal: J Cell Mol Med
Title: SAP deletion promotes malignant insulinoma progression by inducing CXCL12 secretion from CAFs via the CXCR4/p38/ERK signalling pathway.
Volume: 28
Issue: 10
Pages: e18397
•
•
•
•
•
Publication
19443644 | J:164624
First Author: Takabatake Y
Year: 2009
Journal: J Am Soc Nephrol
Title: The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature.
Volume: 20
Issue: 8
Pages: 1714-23
•
•
•
•
•
Publication
22473778 | J:250727
First Author: Marchionni I
Year: 2012
Journal: J Physiol
Title: The chemokine CXCL12 and the HIV-1 envelope protein gp120 regulate spontaneous activity of Cajal-Retzius cells in opposite directions.
Volume: 590
Issue: 13
Pages: 3185-202
•
•
•
•
•
Publication
26400936 | J:226478
First Author: Abe P
Year: 2015
Journal: J Neurosci
Title: Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling.
Volume: 35
Issue: 38
Pages: 13053-63
•
•
•
•
•
Publication
34072818 | J:307829
 
First Author: Ghadge SK
Year: 2021
Journal: Int J Mol Sci
Title: Smooth Muscle Specific Ablation of CXCL12 in Mice Downregulates CXCR7 Associated with Defective Coronary Arteries and Cardiac Hypertrophy.
Volume: 22
Issue: 11
•
•
•
•
•
Publication
23901140 | J:260309
First Author: Smith X
Year: 2013
Journal: Sci Signal
Title: The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76.
Volume: 6
Issue: 286
Pages: ra65
•
•
•
•
•
Publication
37772431 | J:354439
First Author: D'Cruz R
Year: 2023
Journal: J Pathol
Title: Hedgehog signalling in Foxd1+ embryonic kidney stromal progenitors controls nephron formation via Cxcl12 and Wnt5a.
Volume: 261
Issue: 4
Pages: 385-400
•
•
•
•
•
Publication
19141863 | J:151732
First Author: Christopher MJ
Year: 2009
Journal: Blood
Title: Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization.
Volume: 114
Issue: 7
Pages: 1331-9
•
•
•
•
•
Publication
22370717 | J:182700
First Author: Schiraldi M
Year: 2012
Journal: J Exp Med
Title: HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4.
Volume: 209
Issue: 3
Pages: 551-63
•
•
•
•
•
Publication
26017771 | J:239363
First Author: Cavallero S
Year: 2015
Journal: Dev Cell
Title: CXCL12 Signaling Is Essential for Maturation of the Ventricular Coronary Endothelial Plexus and Establishment of Functional Coronary Circulation.
Volume: 33
Issue: 4
Pages: 469-77
•
•
•
•
•
Publication
28174416 | J:241884
First Author: Itkin T
Year: 2017
Journal: Leukemia
Title: MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling.
Volume: 31
Issue: 5
Pages: 1247-1250
•
•
•
•
•
Publication
18925577 | J:143266
First Author: Achatz-Straussberger G
Year: 2008
Journal: Eur J Immunol
Title: Migration of antibody secreting cells towards CXCL12 depends on the isotype that forms the BCR.
Volume: 38
Issue: 11
Pages: 3167-77
•
•
•
•
•
Publication
22645180 | J:189114
First Author: Itkin T
Year: 2012
Journal: Blood
Title: FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.
Volume: 120
Issue: 9
Pages: 1843-55
•
•
•
•
•
Publication
15096537 | J:120190
First Author: Scimone ML
Year: 2004
Journal: J Exp Med
Title: CXCL12 mediates CCR7-independent homing of central memory cells, but not naive T cells, in peripheral lymph nodes.
Volume: 199
Issue: 8
Pages: 1113-20
•
•
•
•
•
Publication
36550214 | J:336536
First Author: Anderson NR
Year: 2023
Journal: Leukemia
Title: Microenvironmental CXCL12 deletion enhances Flt3-ITD acute myeloid leukemia stem cell response to therapy by reducing p38 MAPK signaling.
Volume: 37
Issue: 3
Pages: 560-570
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7435182
Assay Type: RNA in situ
Annotation Date: 2023-02-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3598220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7435180
Age: embryonic day 12.5
Image: 1W
Note: Cxcl12 was not expressed in the malleus and incus condensations and was decreased in stapes condensation.
Specimen Label: 1W
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
21882187 | J:179517
First Author: Tussiwand R
Year: 2011
Journal: Eur J Immunol
Title: The preTCR-dependent DN3 to DP transition requires Notch signaling, is improved by CXCL12 signaling and is inhibited by IL-7 signaling.
Volume: 41
Issue: 11
Pages: 3371-80
•
•
•
•
•
Publication
21703397 | J:173594
First Author: Darisipudi MN
Year: 2011
Journal: Am J Pathol
Title: Dual blockade of the homeostatic chemokine CXCL12 and the proinflammatory chemokine CCL2 has additive protective effects on diabetic kidney disease.
Volume: 179
Issue: 1
Pages: 116-24
•
•
•
•
•
Publication
24449842 | J:208337
First Author: Bodea GO
Year: 2014
Journal: Development
Title: Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system.
Volume: 141
Issue: 3
Pages: 661-73
•
•
•
•
•
Publication
16637021 | J:114909
First Author: Mendes-da-Cruz DA
Year: 2006
Journal: Eur J Immunol
Title: Altered thymocyte migration during experimental acute Trypanosoma cruzi infection: combined role of fibronectin and the chemokines CXCL12 and CCL4.
Volume: 36
Issue: 6
Pages: 1486-93
•
•
•
•
•
Publication
28322746 | J:252562
 
First Author: Janssens R
Year: 2017
Journal: Biochem Pharmacol
Title: Truncation of CXCL12 by CD26 reduces its CXC chemokine receptor 4- and atypical chemokine receptor 3-dependent activity on endothelial cells and lymphocytes.
Volume: 132
Pages: 92-101
•
•
•
•
•
Publication
32049021 | J:288091
First Author: Giri J
Year: 2020
Journal: Cell Rep
Title: CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury.
Volume: 30
Issue: 6
Pages: 1923-1934.e4
•
•
•
•
•
Publication
24663215 | J:211677
First Author: Fleige H
Year: 2014
Journal: J Exp Med
Title: IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs.
Volume: 211
Issue: 4
Pages: 643-51
•
•
•
•
•
Publication
19103804 | J:143512
First Author: Li G
Year: 2009
Journal: Development
Title: Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling.
Volume: 136
Issue: 2
Pages: 327-35
•
•
•
•
•
Publication
20305788 | J:158899
First Author: Berge T
Year: 2010
Journal: PLoS One
Title: T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.
Volume: 5
Issue: 3
Pages: e9761
•
•
•
•
•
Publication
22287708 | J:181251
First Author: Kew RR
Year: 2012
Journal: J Immunol
Title: The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1.
Volume: 188
Issue: 5
Pages: 2380-6
•
•
•
•
•
Publication
20534452 | J:161281
First Author: Carbajal KS
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis.
Volume: 107
Issue: 24
Pages: 11068-73
•
•
•
•
•
GO Term
GO:0097390 | chemokine (C-X-C motif) ligand 12 production
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom