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Search results 1 to 100 out of 555 for Cxcr2

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Hits by Pathway

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Type Details Score
Gene
3579 | CXCR2
Type: gene
Organism: human
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Gene
782719 | CXCR2
Type: gene
Organism: cattle
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Gene
796724 | cxcr2
Type: gene
Organism: zebrafish
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Gene
700407 | CXCR2
Type: gene
Organism: macaque, rhesus
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Gene
101732165 | cxcr2
Type: gene
Organism: frog, western clawed
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Gene
29385 | Cxcr2
Type: gene
Organism: rat
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Gene
478905 | CXCR2
Type: gene
Organism: dog, domestic
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Gene
470644 | CXCR2
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:105303 | Cxcr2
Type: protein_coding_gene
Organism: mouse, laboratory
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GO Term
GO:0045238 | CXCR2 chemokine receptor binding
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Publication
10951241 | J:63935
First Author: Devalaraja RM
Year: 2000
Journal: J Invest Dermatol
Title: Delayed wound healing in CXCR2 knockout mice.
Volume: 115
Issue: 2
Pages: 234-44
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Publication
15004193 | J:88625
First Author: Sue RD
Year: 2004
Journal: J Immunol
Title: CXCR2 is critical to hyperoxia-induced lung injury.
Volume: 172
Issue: 6
Pages: 3860-8
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Publication
31107242 | J:295528
First Author: Capitano ML
Year: 2019
Journal: J Clin Invest
Title: Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling.
Volume: 129
Issue: 6
Pages: 2555-2570
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Publication
18555777 | J:138149
First Author: Acosta JC
Year: 2008
Journal: Cell
Title: Chemokine signaling via the CXCR2 receptor reinforces senescence.
Volume: 133
Issue: 6
Pages: 1006-18
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Publication
25950520 | J:226004
First Author: Steele CW
Year: 2015
Journal: J Pathol
Title: CXCR2 inhibition suppresses acute and chronic pancreatic inflammation.
Volume: 237
Issue: 1
Pages: 85-97
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Publication
14500678 | J:85647
First Author: Ness TL
Year: 2003
Journal: J Immunol
Title: Immunomodulatory role of CXCR2 during experimental septic peritonitis.
Volume: 171
Issue: 7
Pages: 3775-84
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Publication
30517976 | J:295619
First Author: Dyer DP
Year: 2019
Journal: J Leukoc Biol
Title: The chemokine receptor CXCR2 contributes to murine adipocyte development.
Volume: 105
Issue: 3
Pages: 497-506
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Publication
12753603 | J:103539
First Author: Milatovic S
Year: 2003
Journal: Wound Repair Regen
Title: Impaired healing of nitrogen mustard wounds in CXCR2 null mice.
Volume: 11
Issue: 3
Pages: 213-9
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Publication
12626595 | J:82293
First Author: Miller AL
Year: 2003
Journal: J Immunol
Title: CXCR2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction.
Volume: 170
Issue: 6
Pages: 3348-56
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Publication
20610741 | J:166287
First Author: Liu L
Year: 2010
Journal: J Neurosci
Title: Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells.
Volume: 30
Issue: 27
Pages: 9074-83
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Publication
25757087 | J:319071
First Author: Hale SJ
Year: 2015
Journal: Br J Haematol
Title: CXCR2 modulates bone marrow vascular repair and haematopoietic recovery post-transplant.
Volume: 169
Issue: 4
Pages: 552-64
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Publication
24338666 | J:211966
First Author: Lee YS
Year: 2014
Journal: Int J Cancer
Title: CXCR2 inhibition enhances sulindac-mediated suppression of colon cancer development.
Volume: 135
Issue: 1
Pages: 232-7
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Publication
22922255 | J:190744
First Author: Jamieson T
Year: 2012
Journal: J Clin Invest
Title: Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Volume: 122
Issue: 9
Pages: 3127-44
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Publication
18199703 | J:134052
First Author: Amura CR
Year: 2008
Journal: Am J Physiol Cell Physiol
Title: CXCR2 agonists in ADPKD liver cyst fluids promote cell proliferation.
Volume: 294
Issue: 3
Pages: C786-96
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Publication
36311783 | J:333893
 
First Author: Delobel P
Year: 2022
Journal: Front Immunol
Title: CXCR2 intrinsically drives the maturation and function of neutrophils in mice.
Volume: 13
Pages: 1005551
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Publication
31041783 | J:289646
First Author: Hishida T
Year: 2019
Journal: Protein Cell
Title: Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway.
Volume: 10
Issue: 7
Pages: 485-495
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Publication
17656654 | J:127182
First Author: Buanne P
Year: 2007
Journal: J Leukoc Biol
Title: Crucial pathophysiological role of CXCR2 in experimental ulcerative colitis in mice.
Volume: 82
Issue: 5
Pages: 1239-46
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Publication
27222476 | J:236118
First Author: Sinclair A
Year: 2016
Journal: Blood
Title: CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells.
Volume: 128
Issue: 3
Pages: 371-83
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Publication
27265504 | J:232333
First Author: Steele CW
Year: 2016
Journal: Cancer Cell
Title: CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma.
Volume: 29
Issue: 6
Pages: 832-845
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Publication
34260914 | J:330750
First Author: Agarwal P
Year: 2021
Journal: Cell Rep
Title: TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling.
Volume: 36
Issue: 2
Pages: 109386
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Publication
20516641 | J:163726
First Author: Eash KJ
Year: 2010
Journal: J Clin Invest
Title: CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow.
Volume: 120
Issue: 7
Pages: 2423-31
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Publication
31085833 | J:289684
First Author: Karpova D
Year: 2019
Journal: J Clin Invest
Title: Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells.
Volume: 129
Issue: 7
Pages: 2745-2759
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Publication
19118017 | J:143026
First Author: Cataisson C
Year: 2009
Journal: Cancer Res
Title: Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis.
Volume: 69
Issue: 1
Pages: 319-28
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Publication
20044435 | J:157649
First Author: Nemzek JA
Year: 2010
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Functional contribution of CXCR2 to lung injury after aspiration of acid and gastric particulates.
Volume: 298
Issue: 3
Pages: L382-91
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Publication
11714818 | J:72824
First Author: Del Rio L
Year: 2001
Journal: J Immunol
Title: CXCR2 deficiency confers impaired neutrophil recruitment and increased susceptibility during Toxoplasma gondii infection.
Volume: 167
Issue: 11
Pages: 6503-9
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Publication
23986515 | J:202999
First Author: Ranganathan P
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: CXCR2 knockout mice are protected against DSS-colitis-induced acute kidney injury and inflammation.
Volume: 305
Issue: 10
Pages: F1422-7
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Publication
16485040 | J:106505
First Author: Reutershan J
Year: 2006
Journal: J Clin Invest
Title: Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung.
Volume: 116
Issue: 3
Pages: 695-702
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Publication
11801688 | J:73947
First Author: Schuh JM
Year: 2002
Journal: J Immunol
Title: CXCR2 is necessary for the development and persistence of chronic fungal asthma in mice.
Volume: 168
Issue: 3
Pages: 1447-56
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Publication
16094689 | J:113489
First Author: Mihara K
Year: 2005
Journal: Eur J Immunol
Title: Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
Volume: 35
Issue: 9
Pages: 2573-82
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Publication
14978086 | J:88233
First Author: Keane MP
Year: 2004
Journal: J Immunol
Title: Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer.
Volume: 172
Issue: 5
Pages: 2853-60
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Publication
15361358 | J:104756
First Author: Johnston RA
Year: 2005
Journal: Am J Physiol Lung Cell Mol Physiol
Title: CXCR2 is essential for maximal neutrophil recruitment and methacholine responsiveness after ozone exposure.
Volume: 288
Issue: 1
Pages: L61-7
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Publication
30068506 | J:266007
First Author: Yago T
Year: 2018
Journal: Blood
Title: Cooperative PSGL-1 and CXCR2 signaling in neutrophils promotes deep vein thrombosis in mice.
Volume: 132
Issue: 13
Pages: 1426-1437
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Publication
16941672 | J:115957
First Author: Shen H
Year: 2006
Journal: Prostate
Title: Critical and opposing roles of the chemokine receptors CXCR2 and CXCR3 in prostate tumor growth.
Volume: 66
Issue: 16
Pages: 1721-8
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Publication
32019585 | J:298472
First Author: Khaw YM
Year: 2020
Journal: J Neuroinflammation
Title: Neutrophil-selective deletion of Cxcr2 protects against CNS neurodegeneration in a mouse model of multiple sclerosis.
Volume: 17
Issue: 1
Pages: 49
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Publication
31433989 | J:285688
First Author: Di Mitri D
Year: 2019
Journal: Cell Rep
Title: Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer.
Volume: 28
Issue: 8
Pages: 2156-2168.e5
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Publication
23755134 | J:204256
First Author: Reddy AS
Year: 2014
Journal: PLoS One
Title: Central nervous system pathology progresses independently of KC and CXCR2 in globoid-cell leukodystrophy.
Volume: 8
Issue: 6
Pages: e64647
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Publication
16618742 | J:108306
First Author: Wislez M
Year: 2006
Journal: Cancer Res
Title: High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Volume: 66
Issue: 8
Pages: 4198-207
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Publication
32881070 | J:304611
First Author: Sawant KV
Year: 2021
Journal: J Leukoc Biol
Title: Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions.
Volume: 109
Issue: 4
Pages: 777-791
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Publication
12176324 | J:78470
First Author: Tsai HH
Year: 2002
Journal: Cell
Title: The chemokine receptor CXCR2 controls positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration.
Volume: 110
Issue: 3
Pages: 373-83
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Publication
12028561 | J:103682
First Author: Gonçalves AS
Year: 2002
Journal: Scand J Immunol
Title: The involvement of the chemokine receptor CXCR2 in neutrophil recruitment in LPS-induced inflammation and in Mycobacterium avium infection.
Volume: 55
Issue: 6
Pages: 585-91
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Publication
25412626 | J:220190
First Author: Mishra HK
Year: 2015
Journal: J Leukoc Biol
Title: Regulation of CXCR2 expression and function by a disintegrin and metalloprotease-17 (ADAM17).
Volume: 97
Issue: 3
Pages: 447-54
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Publication
27551153 | J:237238
First Author: Bajrami B
Year: 2016
Journal: J Exp Med
Title: G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling.
Volume: 213
Issue: 10
Pages: 1999-2018
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Publication
22326959 | J:184571
First Author: Mei J
Year: 2012
Journal: J Clin Invest
Title: Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice.
Volume: 122
Issue: 3
Pages: 974-86
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Publication
21224471 | J:172615
First Author: Köhler A
Year: 2011
Journal: Blood
Title: G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands.
Volume: 117
Issue: 16
Pages: 4349-57
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Publication
18077323 | J:130586
First Author: Hallgren J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors.
Volume: 104
Issue: 51
Pages: 20478-83
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Publication
21521824 | J:180913
First Author: Zhao C
Year: 2011
Journal: J Lipid Res
Title: TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
Volume: 52
Issue: 7
Pages: 1307-18
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Publication
31573846 | J:282850
First Author: Cui S
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: The antagonist of CXCR1 and CXCR2 protects db/db mice from metabolic diseases through modulating inflammation.
Volume: 317
Issue: 6
Pages: E1205-E1217
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Publication
28763485 | J:245631
First Author: Jee J
Year: 2017
Journal: PLoS One
Title: Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia.
Volume: 12
Issue: 8
Pages: e0182089
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Publication
19864593 | J:157178
First Author: Nagarkar DR
Year: 2009
Journal: J Immunol
Title: CXCR2 is required for neutrophilic airway inflammation and hyperresponsiveness in a mouse model of human rhinovirus infection.
Volume: 183
Issue: 10
Pages: 6698-707
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Publication
21356370 | J:169689
First Author: Eisele NA
Year: 2011
Journal: Am J Pathol
Title: Chemokine receptor CXCR2 mediates bacterial clearance rather than neutrophil recruitment in a murine model of pneumonic plague.
Volume: 178
Issue: 3
Pages: 1190-200
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Publication
32289253 | J:288342
First Author: Teijeira Á
Year: 2020
Journal: Immunity
Title: CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.
Volume: 52
Issue: 5
Pages: 856-871.e8
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Publication
18401338 | J:152873
First Author: Svensson M
Year: 2008
Journal: Kidney Int
Title: Effects of epithelial and neutrophil CXCR2 on innate immunity and resistance to kidney infection.
Volume: 74
Issue: 1
Pages: 81-90
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Publication
24663678 | J:209983
First Author: Sumida H
Year: 2014
Journal: J Immunol
Title: Interplay between CXCR2 and BLT1 facilitates neutrophil infiltration and resultant keratinocyte activation in a murine model of imiquimod-induced psoriasis.
Volume: 192
Issue: 9
Pages: 4361-9
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Publication
24446518 | J:209354
First Author: Mizutani N
Year: 2014
Journal: J Immunol
Title: IL-17A promotes the exacerbation of IL-33-induced airway hyperresponsiveness by enhancing neutrophilic inflammation via CXCR2 signaling in mice.
Volume: 192
Issue: 4
Pages: 1372-84
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Publication
22869904 | J:189842
First Author: Raghuwanshi SK
Year: 2012
Journal: J Immunol
Title: The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions.
Volume: 189
Issue: 6
Pages: 2824-32
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Publication
24321240 | J:314614
First Author: Gong L
Year: 2013
Journal: Mol Cancer
Title: Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase.
Volume: 12
Issue: 1
Pages: 154
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Publication
25765938 | J:250760
First Author: Herlea-Pana O
Year: 2015
Journal: Cardiovasc Res
Title: Chemokine receptors CXCR2 and CX3CR1 differentially regulate functional responses of bone-marrow endothelial progenitors during atherosclerotic plaque regression.
Volume: 106
Issue: 2
Pages: 324-37
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Publication
17603159 | J:124372
First Author: Mihara K
Year: 2007
Journal: Biol Pharm Bull
Title: Functional replacement of murine CXCR2 by its human homologue in the development of atherosclerosis in LDLR knockout mice.
Volume: 30
Issue: 7
Pages: 1231-6
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Publication
34743985 | J:330558
 
First Author: La Cognata V
Year: 2021
Journal: Neurobiol Dis
Title: CXCR2 increases in ALS cortical neurons and its inhibition prevents motor neuron degeneration in vitro and improves neuromuscular function in SOD1G93A mice.
Volume: 160
Pages: 105538
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Publication
16565511 | J:107325
First Author: Boisvert WA
Year: 2006
Journal: Am J Pathol
Title: Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression.
Volume: 168
Issue: 4
Pages: 1385-95
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Publication
18442092 | J:156266
First Author: Lindner M
Year: 2008
Journal: Glia
Title: The chemokine receptor CXCR2 is differentially regulated on glial cells in vivo but is not required for successful remyelination after cuprizone-induced demyelination.
Volume: 56
Issue: 10
Pages: 1104-13
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Publication
31492743 | J:280781
First Author: Neamah WH
Year: 2019
Journal: J Immunol
Title: AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes.
Volume: 203
Issue: 7
Pages: 1830-1844
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Publication
33953162 | J:319853
First Author: Shi X
Year: 2021
Journal: Nat Commun
Title: Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Volume: 12
Issue: 1
Pages: 2547
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Publication
8955112 | J:37299
First Author: Dunstan CA
Year: 1996
Journal: J Biol Chem
Title: Identification of two rat genes orthologous to the human interleukin-8 receptors.
Volume: 271
Issue: 51
Pages: 32770-6
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Publication
19147552 | J:143714
First Author: Singh S
Year: 2009
Journal: Cancer Res
Title: Host CXCR2-dependent regulation of melanoma growth, angiogenesis, and experimental lung metastasis.
Volume: 69
Issue: 2
Pages: 411-5
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Publication
29136508 | J:248839
First Author: Kumar V
Year: 2017
Journal: Cancer Cell
Title: Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors.
Volume: 32
Issue: 5
Pages: 654-668.e5
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Publication
24229710 | J:206735
First Author: Katoh H
Year: 2013
Journal: Cancer Cell
Title: CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis.
Volume: 24
Issue: 5
Pages: 631-44
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Publication
28743719 | J:247010
First Author: Del Prete A
Year: 2017
Journal: Blood
Title: The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage.
Volume: 130
Issue: 10
Pages: 1223-1234
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Publication
23433011 | J:345863
First Author: Zenobia C
Year: 2013
Journal: Cell Microbiol
Title: Commensal bacteria-dependent select expression of CXCL2 contributes to periodontal tissue homeostasis.
Volume: 15
Issue: 8
Pages: 1419-26
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Publication
22865624 | J:204048
First Author: Hogmalm A
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Role of CXC chemokine receptor-2 in a murine model of bronchopulmonary dysplasia.
Volume: 47
Issue: 6
Pages: 746-58
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Publication
23650205 | J:204482
First Author: Liu L
Year: 2013
Journal: Genesis
Title: Functional defect of peripheral neutrophils in mice with induced deletion of CXCR2.
Volume: 51
Issue: 8
Pages: 587-95
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Publication
17028201 | J:117239
First Author: Khan S
Year: 2007
Journal: J Leukoc Biol
Title: The role of CXC chemokine receptor 2 in Pseudomonas aeruginosa corneal infection.
Volume: 81
Issue: 1
Pages: 315-8
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Publication
25756662 | J:233443
First Author: Wilson GC
Year: 2015
Journal: PLoS One
Title: CXC chemokines function as a rheostat for hepatocyte proliferation and liver regeneration.
Volume: 10
Issue: 3
Pages: e0120092
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Publication
21814172 | J:194803
First Author: Svensson M
Year: 2011
Journal: Kidney Int
Title: Acute pyelonephritis and renal scarring are caused by dysfunctional innate immunity in mCxcr2 heterozygous mice.
Volume: 80
Issue: 10
Pages: 1064-72
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Publication
16210641 | J:119108
First Author: Mestas J
Year: 2005
Journal: J Immunol
Title: The role of CXCR2/CXCR2 ligand biological axis in renal cell carcinoma.
Volume: 175
Issue: 8
Pages: 5351-7
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Publication
21704645 | J:178566
First Author: Raman D
Year: 2011
Journal: Toxicol Appl Pharmacol
Title: Chemokines, macrophage inflammatory protein-2 and stromal cell-derived factor-1α, suppress amyloid β-induced neurotoxicity.
Volume: 256
Issue: 3
Pages: 300-13
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Publication
20368349 | J:160181
First Author: Herbold W
Year: 2010
Journal: Infect Immun
Title: Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection.
Volume: 78
Issue: 6
Pages: 2620-30
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Publication
32041848 | J:305049
 
First Author: Timaxian C
Year: 2020
Journal: Life Sci Alliance
Title: The health status alters the pituitary function and reproduction of mice in a Cxcr2-dependent manner.
Volume: 3
Issue: 3
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Publication
33453178 | J:306340
First Author: Purohit A
Year: 2021
Journal: Am J Pathol
Title: Host Cxcr2-Dependent Regulation of Pancreatic Cancer Growth, Angiogenesis, and Metastasis.
Volume: 191
Issue: 4
Pages: 759-771
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Publication
26337969 | J:319156
First Author: Herz J
Year: 2015
Journal: Stroke
Title: Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic Mice.
Volume: 46
Issue: 10
Pages: 2916-25
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Publication
27737879 | J:320226
First Author: Chao T
Year: 2016
Journal: Cancer Immunol Res
Title: CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma.
Volume: 4
Issue: 11
Pages: 968-982
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Publication
25511644 | J:325917
First Author: Sharma B
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