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Search results 1 to 100 out of 1743 for Cxcr4

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
7852 | CXCR4
Type: gene
Organism: human
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Gene
281736 | CXCR4
Type: gene
Organism: cattle
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Gene
395324 | CXCR4
Type: gene
Organism: chicken
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Gene
707329 | CXCR4
Type: gene
Organism: macaque, rhesus
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Gene
100038176 | cxcr4
Type: gene
Organism: frog, western clawed
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Gene
119863891 | CXCR4
Type: gene
Organism: dog, domestic
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Gene
60628 | Cxcr4
Type: gene
Organism: rat
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Gene
450130 | CXCR4
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:109563 | Cxcr4
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:7543789
Assay Type: Immunohistochemistry
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7544062
Age: embryonic day 16.5
Image: 3J Cxcr4
Specimen Label: 3J Cxcr4
Detected: true
Specimen Num: 1
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GO Term
GO:0031723 | CXCR4 chemokine receptor binding
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GXD Expression
GXD Expression
   
Probe: MGI:4938629
Assay Type: RT-PCR
Annotation Date: 2011-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:4938634
Age: embryonic day 11.5
Image: 5
Specimen Label: Cxcr4 +/+
Detected: true
Specimen Num: 7
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GO Term
GO:0038160 | CXCL12-activated CXCR4 signaling pathway
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Publication
18378795 | J:133973
First Author: Nie Y
Year: 2008
Journal: J Exp Med
Title: CXCR4 is required for the quiescence of primitive hematopoietic cells.
Volume: 205
Issue: 4
Pages: 777-83
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Publication
37045841 | J:335319
First Author: Anginot A
Year: 2023
Journal: Nat Commun
Title: WHIM Syndrome-linked CXCR4 mutations drive osteoporosis.
Volume: 14
Issue: 1
Pages: 2058
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Publication
26458529 | J:231840
 
First Author: Cash-Padgett T
Year: 2016
Journal: Neurosci Res
Title: Increased stereotypy in conditional Cxcr4 knockout mice.
Volume: 105
Pages: 75-9
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Publication
20010845 | J:158414
First Author: Trampont PC
Year: 2010
Journal: Nat Immunol
Title: CXCR4 acts as a costimulator during thymic beta-selection.
Volume: 11
Issue: 2
Pages: 162-70
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Publication
9634238 | J:69255
First Author: Zou YR
Year: 1998
Journal: Nature
Title: Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development.
Volume: 393
Issue: 6685
Pages: 595-9
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Publication
26190113 | J:232524
First Author: Roccaro AM
Year: 2015
Journal: Cell Rep
Title: CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation.
Volume: 12
Issue: 4
Pages: 622-35
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Publication
20880358 | J:169500
First Author: Burbassi S
Year: 2010
Journal: Eur J Neurosci
Title: Alterations of CXCR4 function in μ-opioid receptor-deficient glia.
Volume: 32
Issue: 8
Pages: 1278-88
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GO Term
GO:0038159 | C-X-C chemokine receptor CXCR4 signaling pathway
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Publication
12832536 | J:84362
First Author: Stumm RK
Year: 2003
Journal: J Neurosci
Title: CXCR4 regulates interneuron migration in the developing neocortex.
Volume: 23
Issue: 12
Pages: 5123-30
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Publication
27681431 | J:240571
First Author: Biajoux V
Year: 2016
Journal: Cell Rep
Title: Efficient Plasma Cell Differentiation and Trafficking Require Cxcr4 Desensitization.
Volume: 17
Issue: 1
Pages: 193-205
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Publication
18435916 | J:136264
First Author: Wang X
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Hypoxia enhances CXCR4 expression favoring microglia migration via HIF-1alpha activation.
Volume: 371
Issue: 2
Pages: 283-8
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Publication
11983855 | J:81783
First Author: Lu M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor.
Volume: 99
Issue: 10
Pages: 7090-5
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Publication
28550161 | J:244671
First Author: Freitas C
Year: 2017
Journal: J Exp Med
Title: Lymphoid differentiation of hematopoietic stem cells requires efficient Cxcr4 desensitization.
Volume: 214
Issue: 7
Pages: 2023-2040
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Publication
24816217 | J:225633
 
First Author: Bot I
Year: 2014
Journal: J Mol Cell Cardiol
Title: CXCR4 blockade induces atherosclerosis by affecting neutrophil function.
Volume: 74
Pages: 44-52
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Publication
24961298 | J:329030
 
First Author: Menichella DM
Year: 2014
Journal: Mol Pain
Title: CXCR4 chemokine receptor signaling mediates pain in diabetic neuropathy.
Volume: 10
Pages: 42
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Publication
34363012 | J:310831
First Author: Lewis R
Year: 2021
Journal: Leukemia
Title: CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness.
Volume: 35
Issue: 10
Pages: 2895-2905
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GXD Expression
GXD Expression
   
Probe: MGI:6170599
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190076
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Cxcr4
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6170599
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190076
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Cxcr4
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6170599
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190076
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Cxcr4
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6170599
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190076
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Cxcr4
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6170599
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190076
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Cxcr4
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6170599
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190076
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Cxcr4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6170599
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190076
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Cxcr4
Detected: true
Specimen Num: 7
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Publication
23881789 | J:329034
First Author: Leucht P
Year: 2013
Journal: J Orthop Res
Title: CXCR4 antagonism attenuates load-induced periosteal bone formation in mice.
Volume: 31
Issue: 11
Pages: 1828-38
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Publication
31845480 | J:284781
First Author: Borna S
Year: 2020
Journal: J Cell Mol Med
Title: Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis.
Volume: 24
Issue: 2
Pages: 1980-1992
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Publication
31071921 | J:289614
 
First Author: LaRocca TJ
Year: 2019
Journal: Int J Mol Sci
Title: CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy.
Volume: 20
Issue: 9
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Publication
23528817 | J:202414
First Author: Takekoshi T
Year: 2013
Journal: J Invest Dermatol
Title: CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis.
Volume: 133
Issue: 11
Pages: 2530-2537
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Publication
17715292 | J:124901
First Author: Hirbe AC
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Disruption of CXCR4 enhances osteoclastogenesis and tumor growth in bone.
Volume: 104
Issue: 35
Pages: 14062-7
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Publication
32042176 | J:288822
First Author: Werner Y
Year: 2020
Journal: Nat Neurosci
Title: Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke.
Volume: 23
Issue: 3
Pages: 351-362
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Publication
23669394 | J:200954
First Author: Schmidt TH
Year: 2013
Journal: J Exp Med
Title: CXCR4 promotes B cell egress from Peyer's patches.
Volume: 210
Issue: 6
Pages: 1099-107
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Publication
31921208 | J:298501
 
First Author: Mcheik S
Year: 2019
Journal: Front Immunol
Title: Coexpression of CCR7 and CXCR4 During B Cell Development Controls CXCR4 Responsiveness and Bone Marrow Homing.
Volume: 10
Pages: 2970
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Publication
21220099 | J:223711
First Author: Wang Y
Year: 2011
Journal: Neuron
Title: CXCR4 and CXCR7 have distinct functions in regulating interneuron migration.
Volume: 69
Issue: 1
Pages: 61-76
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Publication
20534485 | J:161391
First Author: Patel JR
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination.
Volume: 107
Issue: 24
Pages: 11062-7
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Publication
25537742 | J:237549
First Author: Yuan A
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Chemokine receptor Cxcr4 contributes to kidney fibrosis via multiple effectors.
Volume: 308
Issue: 5
Pages: F459-72
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Publication
23474530 | J:194910
First Author: Xie J
Year: 2013
Journal: Cell Immunol
Title: Notch signaling regulates CXCR4 expression and the migration of mesenchymal stem cells.
Volume: 281
Issue: 1
Pages: 68-75
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Publication
12583436 | J:80760
First Author: Hovden AO
Year: 2002
Journal: APMIS
Title: The influence of CD4 and CXCR4 on maedi-visna virus-induced syncytium formation.
Volume: 110
Issue: 10
Pages: 697-708
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Publication
35926459 | J:327277
First Author: Venkataramanappa S
Year: 2022
Journal: Cell Rep
Title: Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers.
Volume: 40
Issue: 5
Pages: 111157
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Publication
36148060 | J:329018
 
First Author: Winnicki A
Year: 2022
Journal: Front Cardiovasc Med
Title: Role of endothelial CXCR4 in the development of aortic valve stenosis.
Volume: 9
Pages: 971321
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Publication
21911833 | J:178789
First Author: Mayol K
Year: 2011
Journal: Blood
Title: Sequential desensitization of CXCR4 and S1P5 controls natural killer cell trafficking.
Volume: 118
Issue: 18
Pages: 4863-71
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Publication
31852686 | J:284164
 
First Author: Niimi K
Year: 2020
Journal: Development
Title: FOXO1 regulates developmental lymphangiogenesis by upregulating CXCR4 in the mouse-tail dermis.
Volume: 147
Issue: 2
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Publication
24953490 | J:329028
First Author: Jung SH
Year: 2014
Journal: Atherosclerosis
Title: DJ-1 protein regulates CD3+ T cell migration via overexpression of CXCR4 receptor.
Volume: 235
Issue: 2
Pages: 503-9
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Publication
9634237 | J:69256
First Author: Tachibana K
Year: 1998
Journal: Nature
Title: The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract.
Volume: 393
Issue: 6685
Pages: 591-4
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Publication
24646609 | J:329035
First Author: Wang ER
Year: 2014
Journal: Gene Ther
Title: Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration.
Volume: 21
Issue: 5
Pages: 496-506
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Publication
33512437 | J:327651
First Author: Alouche N
Year: 2021
Journal: Blood
Title: Hematologic disorder-associated Cxcr4 gain-of-function mutation leads to uncontrolled extrafollicular immune response.
Volume: 137
Issue: 22
Pages: 3050-3063
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Publication
18495324 | J:141682
First Author: Iyer CV
Year: 2008
Journal: Exp Hematol
Title: Rapid and recurrent neutrophil mobilization regulated by T134, a CXCR4 peptide antagonist.
Volume: 36
Issue: 9
Pages: 1098-109
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Publication
20516641 | J:163726
First Author: Eash KJ
Year: 2010
Journal: J Clin Invest
Title: CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow.
Volume: 120
Issue: 7
Pages: 2423-31
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Publication
23469143 | J:197260
First Author: de Poorter C
Year: 2013
Journal: PLoS One
Title: Consequences of ChemR23 heteromerization with the chemokine receptors CXCR4 and CCR7.
Volume: 8
Issue: 2
Pages: e58075
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Publication
14568925 | J:132791
First Author: Plotkin J
Year: 2003
Journal: J Immunol
Title: Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus.
Volume: 171
Issue: 9
Pages: 4521-7
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Publication
17889832 | J:127352
First Author: Liang Z
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Blockade of invasion and metastasis of breast cancer cells via targeting CXCR4 with an artificial microRNA.
Volume: 363
Issue: 3
Pages: 542-6
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Publication
19384956 | J:148407
First Author: Ueland J
Year: 2009
Journal: Dev Dyn
Title: A novel role for the chemokine receptor Cxcr4 in kidney morphogenesis: an in vitro study.
Volume: 238
Issue: 5
Pages: 1083-91
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Publication
24973450 | J:309265
First Author: Chaix J
Year: 2014
Journal: J Immunol
Title: Cutting edge: CXCR4 is critical for CD8+ memory T cell homeostatic self-renewal but not rechallenge self-renewal.
Volume: 193
Issue: 3
Pages: 1013-6
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Publication
18279715 | J:132714
First Author: Skinner AM
Year: 2008
Journal: Exp Hematol
Title: CXCR4 induction in hematopoietic progenitor cells from Fanca(-/-), -c(-/-), and -d2(-/-) mice.
Volume: 36
Issue: 3
Pages: 273-82
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Publication
27340942 | J:238360
First Author: Shi X
Year: 2016
Journal: Stem Cells
Title: Local CXCR4 Upregulation in the Injured Arterial Wall Contributes to Intimal Hyperplasia.
Volume: 34
Issue: 11
Pages: 2744-2757
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Publication
21270405 | J:169389
First Author: Yoshida N
Year: 2011
Journal: J Immunol
Title: CXCR4 expression on activated B cells is downregulated by CD63 and IL-21.
Volume: 186
Issue: 5
Pages: 2800-8
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Publication
15520246 | J:94911
First Author: Nie Y
Year: 2004
Journal: J Exp Med
Title: The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunity.
Volume: 200
Issue: 9
Pages: 1145-56
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Publication
36088505 | J:330352
First Author: Ahn S
Year: 2022
Journal: Oncogene
Title: CXCR4 and CXCR7 signaling promotes tumor progression and obesity-associated epithelial-mesenchymal transition in prostate cancer cells.
Volume: 41
Issue: 41
Pages: 4633-4644
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Publication
21124917 | J:167314
First Author: Cronshaw DG
Year: 2010
Journal: PLoS One
Title: An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis.
Volume: 5
Issue: 11
Pages: e15397
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Publication
26058076 | J:222918
First Author: Passaro D
Year: 2015
Journal: Cancer Cell
Title: CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia.
Volume: 27
Issue: 6
Pages: 769-79
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Publication
32606001 | J:296622
First Author: Morita T
Year: 2020
Journal: Cancer Res
Title: CXCR4 in Tumor Epithelial Cells Mediates Desmoplastic Reaction in Pancreatic Ductal Adenocarcinoma.
Volume: 80
Issue: 19
Pages: 4058-4070
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Publication
26755698 | J:229008
First Author: Escot S
Year: 2016
Journal: Development
Title: Disruption of CXCR4 signaling in pharyngeal neural crest cells causes DiGeorge syndrome-like malformations.
Volume: 143
Issue: 4
Pages: 582-8
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Publication
24718993 | J:213419
First Author: Abe P
Year: 2014
Journal: Development
Title: CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons.
Volume: 141
Issue: 9
Pages: 1857-63
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Publication
28400375 | J:242010
First Author: Karpova D
Year: 2017
Journal: Blood
Title: Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells.
Volume: 129
Issue: 21
Pages: 2939-2949
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Publication
33512478 | J:327653
First Author: Gallego C
Year: 2021
Journal: Blood
Title: CXCR4 signaling controls dendritic cell location and activation at steady state and in inflammation.
Volume: 137
Issue: 20
Pages: 2770-2784
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Publication
20007826 | J:164109
First Author: Sengupta N
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization.
Volume: 51
Issue: 5
Pages: 2697-704
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Publication
25403444 | J:337986
First Author: Beck TC
Year: 2014
Journal: J Exp Med
Title: CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow.
Volume: 211
Issue: 13
Pages: 2567-81
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Publication
33435128 | J:306219
 
First Author: Kim J
Year: 2021
Journal: Int J Mol Sci
Title: CXCR4 Regulates Temporal Differentiation via PRC1 Complex in Organogenesis of Epithelial Glands.
Volume: 22
Issue: 2
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Publication
37815869 | J:343444
 
First Author: Lyu F
Year: 2023
Journal: JCI Insight
Title: Maternal CXCR4 deletion results in placental defects and pregnancy loss mediated by immune dysregulation.
Volume: 8
Issue: 21
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Publication
22438253 | J:186735
First Author: Balabanian K
Year: 2012
Journal: Blood
Title: Proper desensitization of CXCR4 is required for lymphocyte development and peripheral compartmentalization in mice.
Volume: 119
Issue: 24
Pages: 5722-30
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Publication
26967480 | J:231152
First Author: Meuris F
Year: 2016
Journal: J Invest Dermatol
Title: Symptomatic Improvement in Human Papillomavirus-Induced Epithelial Neoplasia by Specific Targeting of the CXCR4 Chemokine Receptor.
Volume: 136
Issue: 2
Pages: 473-80
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Publication
26519029 | J:231349
First Author: Mayorga M
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Early upregulation of myocardial CXCR4 expression is critical for dimethyloxalylglycine-induced cardiac improvement in acute myocardial infarction.
Volume: 310
Issue: 1
Pages: H20-8
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Publication
22345572 | J:187489
First Author: Ghosh MC
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2.
Volume: 302
Issue: 9
Pages: L846-56
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Publication
17596540 | J:147014
First Author: De La Luz Sierra M
Year: 2007
Journal: Blood
Title: Transcription factor Gfi-1 induced by G-CSF is a negative regulator of CXCR4 in myeloid cells.
Volume: 110
Issue: 7
Pages: 2276-85
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Publication
19064997 | J:147597
First Author: Dubeykovskaya Z
Year: 2009
Journal: J Biol Chem
Title: Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines.
Volume: 284
Issue: 6
Pages: 3650-62
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Publication
22992418 | J:190102
First Author: Otani Y
Year: 2012
Journal: FEBS Lett
Title: Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016.
Volume: 586
Issue: 20
Pages: 3639-44
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Publication
24723559 | J:223610
First Author: Noels H
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Deficiency of endothelial CXCR4 reduces reendothelialization and enhances neointimal hyperplasia after vascular injury in atherosclerosis-prone mice.
Volume: 34
Issue: 6
Pages: 1209-20
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Publication
24752354 | J:215177
First Author: Geherin SA
Year: 2014
Journal: PLoS One
Title: CXCR4 is dispensable for T cell egress from chronically inflamed skin via the afferent lymph.
Volume: 9
Issue: 4
Pages: e95626
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Publication
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Title: Loss of Cxcr4 in Endometriosis Reduces Proliferation and Lesion Number while Increasing Intraepithelial Lymphocyte Infiltration.
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Title: CXCR4 signaling and function require the expression of the IgD-class B-cell antigen receptor.
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