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Search results 1 to 100 out of 418 for Cyp1b1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Cytochrome P450 1B1 (CYP1B1) is an enzyme that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics [, ]. It has been linked to primary congenital glaucoma []and cancers [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Choudhary D
Year: 2004
Journal: Drug Metab Dispos
Title: Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1.
Volume: 32
Issue: 8
Pages: 840-7
Gene
Type: gene
Organism: human
Publication
First Author: Madeen EP
Year: 2017
Journal: Mol Carcinog
Title: Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
Volume: 56
Issue: 1
Pages: 163-171
Publication
First Author: Li F
Year: 2014
Journal: J Proteome Res
Title: Lipidomics reveals a link between CYP1B1 and SCD1 in promoting obesity.
Volume: 13
Issue: 5
Pages: 2679-87
Publication
First Author: Nishida CR
Year: 2013
Journal: Mol Pharmacol
Title: Specificity determinants of CYP1B1 estradiol hydroxylation.
Volume: 84
Issue: 3
Pages: 451-8
Publication  
First Author: Mitsui Y
Year: 2015
Journal: BMC Cancer
Title: CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma.
Volume: 15
Pages: 942
Publication
First Author: Dong H
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins.
Volume: 435
Issue: 4
Pages: 727-32
Publication
First Author: Palenski TL
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: Cyp1B1 expression promotes angiogenesis by suppressing NF-κB activity.
Volume: 305
Issue: 11
Pages: C1170-84
Publication
First Author: Buters JT
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas.
Volume: 96
Issue: 5
Pages: 1977-82
Publication
First Author: Choudhary D
Year: 2007
Journal: Drug Metab Dispos
Title: Cyp1b1 protein in the mouse eye during development: an immunohistochemical study.
Volume: 35
Issue: 6
Pages: 987-94
Publication
First Author: Alexander DL
Year: 1997
Journal: Cancer Res
Title: Ah receptor regulation of CYP1B1 expression in primary mouse embryo-derived cells.
Volume: 57
Issue: 20
Pages: 4498-506
Publication
First Author: Tang Y
Year: 2009
Journal: Blood
Title: CYP1B1 expression promotes the proangiogenic phenotype of endothelium through decreased intracellular oxidative stress and thrombospondin-2 expression.
Volume: 113
Issue: 3
Pages: 744-54
Publication
First Author: Palenski TL
Year: 2013
Journal: Lab Invest
Title: Lack of Cyp1b1 promotes the proliferative and migratory phenotype of perivascular supporting cells.
Volume: 93
Issue: 6
Pages: 646-62
Publication
First Author: Dempsie Y
Year: 2013
Journal: Cardiovasc Res
Title: Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension.
Volume: 99
Issue: 1
Pages: 24-34
Publication
First Author: Falero-Perez J
Year: 2018
Journal: PLoS One
Title: Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells.
Volume: 13
Issue: 10
Pages: e0206756
Publication  
First Author: Falero-Perez J
Year: 2019
Journal: Trends Dev Biol
Title: Targeted deletion of Cyp1b1 in pericytes results in attenuation of retinal neovascularization and trabecular meshwork dysgenesis.
Volume: 12
Pages: 1-12
Publication
First Author: Ye G
Year: 2023
Journal: Exp Mol Med
Title: ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression.
Volume: 55
Issue: 8
Pages: 1743-1756
Publication
First Author: Zhao Y
Year: 2013
Journal: Mol Cell Biol
Title: Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress.
Volume: 33
Issue: 21
Pages: 4225-40
Publication
First Author: Zheng W
Year: 2013
Journal: Arch Biochem Biophys
Title: Stimulation of mouse Cyp1b1 during adipogenesis: characterization of promoter activation by the transcription factor Pax6.
Volume: 532
Issue: 1
Pages: 1-14
Publication  
First Author: Bushkofsky JR
Year: 2016
Journal: Arch Biochem Biophys
Title: Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα.
Volume: 597
Pages: 30-47
Publication  
First Author: Maguire M
Year: 2017
Journal: Mol Cell Endocrinol
Title: Cyp1b1 deletion and retinol deficiency coordinately suppress mouse liver lipogenic genes and hepcidin expression during post-natal development.
Volume: 454
Pages: 50-68
Publication
First Author: Kerzee JK
Year: 2001
Journal: Circ Res
Title: Constitutive and inducible expression of Cyp1a1 and Cyp1b1 in vascular smooth muscle cells: role of the Ahr bHLH/PAS transcription factor.
Volume: 89
Issue: 7
Pages: 573-82
Publication
First Author: Maguire M
Year: 2020
Journal: PLoS One
Title: Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development.
Volume: 15
Issue: 2
Pages: e0228436
Publication
First Author: Tang Y
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: CYP1B1 and endothelial nitric oxide synthase combine to sustain proangiogenic functions of endothelial cells under hyperoxic stress.
Volume: 298
Issue: 3
Pages: C665-78
Publication
First Author: Smerdová L
Year: 2014
Journal: Carcinogenesis
Title: Upregulation of CYP1B1 expression by inflammatory cytokines is mediated by the p38 MAP kinase signal transduction pathway.
Volume: 35
Issue: 11
Pages: 2534-43
Publication
First Author: Dragin N
Year: 2006
Journal: J Biol Chem
Title: For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.
Volume: 281
Issue: 27
Pages: 18591-600
Protein
Organism: Mus musculus/domesticus
Length: 543  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 307  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 324  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 543  
Fragment?: false
Publication
First Author: Shimada T
Year: 1999
Journal: Carcinogenesis
Title: Catalytic properties of polymorphic human cytochrome P450 1B1 variants.
Volume: 20
Issue: 8
Pages: 1607-13
Publication
First Author: Zhao Y
Year: 2015
Journal: J Ophthalmic Vis Res
Title: Cytochrome P450 1B1 and Primary Congenital Glaucoma.
Volume: 10
Issue: 1
Pages: 60-7
Publication
First Author: Wei YK
Year: 2015
Journal: J Environ Pathol Toxicol Oncol
Title: Genistein Induces Cytochrome P450 1B1 Gene Expression and Cell Proliferation in Human Breast Cancer MCF-7 Cells.
Volume: 34
Issue: 2
Pages: 153-9
Publication
First Author: Uno S
Year: 2006
Journal: Mol Pharmacol
Title: Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.
Volume: 69
Issue: 4
Pages: 1103-14
Publication  
First Author: Larsen MC
Year: 2023
Journal: Int J Mol Sci
Title: AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors.
Volume: 24
Issue: 23
Publication
First Author: Savas U
Year: 1997
Journal: Arch Biochem Biophys
Title: Biological oxidations and P450 reactions. Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1.
Volume: 347
Issue: 2
Pages: 181-92
Publication
First Author: Siddens LK
Year: 2015
Journal: Toxicol Appl Pharmacol
Title: Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.
Volume: 287
Issue: 2
Pages: 149-60
Publication
First Author: Shen Z
Year: 1994
Journal: DNA Cell Biol
Title: cDNA cloning, sequence analysis, and induction by aryl hydrocarbons of a murine cytochrome P450 gene, Cyp1b1.
Volume: 13
Issue: 7
Pages: 763-9
Publication
First Author: Sarfarazi M
Year: 2003
Journal: Ophthalmol Clin North Am
Title: Genetics and biochemistry of primary congenital glaucoma.
Volume: 16
Issue: 4
Pages: 543-54, vi
Publication
First Author: Libby RT
Year: 2003
Journal: Science
Title: Modification of ocular defects in mouse developmental glaucoma models by tyrosinase.
Volume: 299
Issue: 5612
Pages: 1578-81
Publication  
First Author: Grimm SL
Year: 2023
Journal: Redox Biol
Title: Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation.
Volume: 64
Pages: 102790
Publication
First Author: Heidel SM
Year: 2000
Journal: Cancer Res
Title: Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7,12-dimethylbenz[a]anthracene.
Volume: 60
Issue: 13
Pages: 3454-60
Publication
First Author: Falero-Perez J
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Cyp1b1-deficient retinal astrocytes are more proliferative and migratory and are protected from oxidative stress and inflammation.
Volume: 316
Issue: 6
Pages: C767-C781
Publication
First Author: Ward JM
Year: 2004
Journal: Toxicol Pathol
Title: Progressive glomerulonephritis and histiocytic sarcoma associated with macrophage functional defects in CYP1B1-deficient mice.
Volume: 32
Issue: 6
Pages: 710-8
Publication  
First Author: Larsen MC
Year: 2015
Journal: Arch Biochem Biophys
Title: Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis.
Volume: 571
Pages: 21-39
Publication
First Author: Peng J
Year: 2013
Journal: Carcinogenesis
Title: Estrogen metabolism within the lung and its modulation by tobacco smoke.
Volume: 34
Issue: 4
Pages: 909-15
Publication
First Author: Lewis JM
Year: 2015
Journal: J Invest Dermatol
Title: Mechanisms of chemical cooperative carcinogenesis by epidermal Langerhans cells.
Volume: 135
Issue: 5
Pages: 1405-1414
Publication
First Author: McLellan RA
Year: 2000
Journal: Arch Biochem Biophys
Title: Characterization and functional analysis of two common human cytochrome P450 1B1 variants.
Volume: 378
Issue: 1
Pages: 175-81
Publication
First Author: Jennings BL
Year: 2012
Journal: Hypertension
Title: Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice.
Volume: 59
Issue: 2
Pages: 348-54
Publication
First Author: Gálvez-Peralta M
Year: 2013
Journal: Int J Cancer
Title: Oral benzo[a]pyrene in Cyp1a1/1b1(-/-) double-knockout mice: Microarray analysis during squamous cell carcinoma formation in preputial gland duct.
Volume: 132
Issue: 9
Pages: 2065-75
Publication
First Author: Xu M
Year: 2004
Journal: Toxicol Appl Pharmacol
Title: Determination of murine fetal Cyp1a1 and 1b1 expression by real-time fluorescence reverse transcription-polymerase chain reaction.
Volume: 201
Issue: 3
Pages: 295-302
Publication
First Author: Savas U
Year: 1994
Journal: J Biol Chem
Title: Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression.
Volume: 269
Issue: 21
Pages: 14905-11
Publication
First Author: White K
Year: 2012
Journal: Circulation
Title: Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension.
Volume: 126
Issue: 9
Pages: 1087-98
Publication
First Author: Dinu D
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury.
Volume: 476
Issue: 4
Pages: 346-351
Publication  
First Author: Amirmokhtari N
Year: 2021
Journal: Front Cell Dev Biol
Title: Absence of Cytochrome P450-1b1 Increases Susceptibility of Pressure-Induced Axonopathy in the Murine Retinal Projection.
Volume: 9
Pages: 636321
Publication
First Author: Gao J
Year: 2005
Journal: Toxicol Sci
Title: Cytochrome P450 1B1 is required for 7,12-dimethylbenz(a)-anthracene (DMBA) induced spleen cell immunotoxicity.
Volume: 86
Issue: 1
Pages: 68-74
Publication
First Author: Bhattacharyya KK
Year: 1995
Journal: J Biol Chem
Title: Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation.
Volume: 270
Issue: 19
Pages: 11595-602
Publication  
First Author: Stoilov I
Year: 2004
Journal: Mol Vis
Title: Expression of cytochrome P4501b1 (Cyp1b1) during early murine development.
Volume: 10
Pages: 629-36
Publication
First Author: Mukherjee K
Year: 2018
Journal: J Am Heart Assoc
Title: Cytochrome P450 1B1 Is Critical for Neointimal Growth in Wire-Injured Carotid Artery of Male Mice.
Volume: 7
Issue: 18
Pages: e010065
Publication
First Author: Song CY
Year: 2016
Journal: Hypertension
Title: Cytochrome P450 1B1 Contributes to the Development of Atherosclerosis and Hypertension in Apolipoprotein E-Deficient Mice.
Volume: 67
Issue: 1
Pages: 206-13
Publication
First Author: Pingili AK
Year: 2016
Journal: Hypertension
Title: 6β-Hydroxytestosterone, a Cytochrome P450 1B1-Testosterone-Metabolite, Mediates Angiotensin II-Induced Renal Dysfunction in Male Mice.
Volume: 67
Issue: 5
Pages: 916-26
Publication
First Author: Thirunavukkarasu S
Year: 2016
Journal: Am J Pathol
Title: Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice.
Volume: 186
Issue: 8
Pages: 2204-2219
Publication  
First Author: Mair KM
Year: 2019
Journal: Eur Respir J
Title: Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension.
Volume: 53
Issue: 6
Publication
First Author: Choudhary D
Year: 2005
Journal: Arch Biochem Biophys
Title: Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.
Volume: 436
Issue: 1
Pages: 50-61
Publication
First Author: Hwang DY
Year: 2001
Journal: Arch Biochem Biophys
Title: Xenobiotic response in humanized double transgenic mice expressing tetracycline-controlled transactivator and human CYP1B1.
Volume: 395
Issue: 1
Pages: 32-40
Publication
First Author: Pingili AK
Year: 2020
Journal: Biol Sex Differ
Title: 6β-Hydroxytestosterone, a metabolite of testosterone generated by CYP1B1, contributes to vascular changes in angiotensin II-induced hypertension in male mice.
Volume: 11
Issue: 1
Pages: 4
Publication
First Author: Iqbal J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes.
Volume: 110
Issue: 27
Pages: 11115-20
Publication
First Author: Bansal S
Year: 2014
Journal: J Biol Chem
Title: Mitochondrial targeting of cytochrome P450 (CYP) 1B1 and its role in polycyclic aromatic hydrocarbon-induced mitochondrial dysfunction.
Volume: 289
Issue: 14
Pages: 9936-51
Publication
First Author: Uno S
Year: 2008
Journal: Free Radic Biol Med
Title: Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.
Volume: 44
Issue: 4
Pages: 570-83
Publication  
First Author: Stading R
Year: 2024
Journal: Free Radic Biol Med
Title: Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1.
Volume: 211
Pages: 35-46
Publication
First Author: Gonzalez FJ
Year: 1999
Journal: Cancer Lett
Title: Role of gene knockout mice in understanding the mechanisms of chemical toxicity and carcinogenesis.
Volume: 143
Issue: 2
Pages: 199-204
Publication
First Author: MacPherson L
Year: 2013
Journal: Nucleic Acids Res
Title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation.
Volume: 41
Issue: 3
Pages: 1604-21
Publication
First Author: Shertzer HG
Year: 2007
Journal: Carcinogenesis
Title: 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.
Volume: 28
Issue: 6
Pages: 1371-8
Publication  
First Author: Alessandrini F
Year: 2022
Journal: Front Immunol
Title: Lung Epithelial CYP1 Activity Regulates Aryl Hydrocarbon Receptor Dependent Allergic Airway Inflammation.
Volume: 13
Pages: 901194
Publication
First Author: Shin S
Year: 2007
Journal: Mol Cell Biol
Title: NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.
Volume: 27
Issue: 20
Pages: 7188-97
Publication
First Author: Borland MG
Year: 2014
Journal: Carcinogenesis
Title: Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes.
Volume: 35
Issue: 7
Pages: 1602-12
Publication
First Author: Nebert DW
Year: 2004
Journal: J Biol Chem
Title: Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer.
Volume: 279
Issue: 23
Pages: 23847-50
Publication
First Author: Dragin N
Year: 2008
Journal: Mol Pharmacol
Title: Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse.
Volume: 73
Issue: 6
Pages: 1844-56
Publication
First Author: Behesti H
Year: 2009
Journal: Dev Biol
Title: Loss of Tbx2 delays optic vesicle invagination leading to small optic cups.
Volume: 333
Issue: 2
Pages: 360-72
Publication
First Author: Choudhary D
Year: 2003
Journal: Arch Biochem Biophys
Title: Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.
Volume: 414
Issue: 1
Pages: 91-100
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory