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Search results 1 to 100 out of 388 for Cyp2e1

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0.047s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Cheung C
Year: 2005
Journal: Drug Metab Dispos
Title: The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity.
Volume: 33
Issue: 3
Pages: 449-57
Publication  
First Author: Cederbaum AI
Year: 2014
Journal: Redox Biol
Title: Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction.
Volume: 2
Pages: 1048-54
Publication
First Author: Kang JS
Year: 2008
Journal: Toxicol Appl Pharmacol
Title: Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity.
Volume: 228
Issue: 3
Pages: 295-300
Publication
First Author: Cheng J
Year: 2013
Journal: Toxicol Sci
Title: Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping.
Volume: 135
Issue: 1
Pages: 37-47
Publication
First Author: Konstandi M
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Sex steroid hormones regulate constitutive expression of Cyp2e1 in female mouse liver.
Volume: 304
Issue: 10
Pages: E1118-28
Publication
First Author: Kang JS
Year: 2007
Journal: Cancer Res
Title: Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo.
Volume: 67
Issue: 23
Pages: 11141-6
Publication
First Author: Lee SS
Year: 1996
Journal: J Biol Chem
Title: Role of CYP2E1 in the hepatotoxicity of acetaminophen.
Volume: 271
Issue: 20
Pages: 12063-7
Publication
First Author: Powley MW
Year: 2001
Journal: Toxicology
Title: Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice.
Volume: 169
Issue: 3
Pages: 187-94
Publication  
First Author: Abdelmegeed MA
Year: 2013
Journal: Free Radic Biol Med
Title: CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis.
Volume: 65
Pages: 1238-1245
Publication
First Author: Zaher H
Year: 1998
Journal: Toxicol Appl Pharmacol
Title: Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice.
Volume: 152
Issue: 1
Pages: 193-9
Publication
First Author: Wong FW
Year: 1998
Journal: Toxicol Appl Pharmacol
Title: Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression.
Volume: 153
Issue: 1
Pages: 109-18
Publication
First Author: Zong H
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance.
Volume: 302
Issue: 5
Pages: E532-9
Publication
First Author: Forkert PG
Year: 1991
Journal: Carcinogenesis
Title: Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration.
Volume: 12
Issue: 12
Pages: 2259-68
Publication
First Author: Leclercq IA
Year: 2000
Journal: J Clin Invest
Title: CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis.
Volume: 105
Issue: 8
Pages: 1067-75
Publication
First Author: Valentine JL
Year: 1996
Journal: Toxicol Appl Pharmacol
Title: Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression.
Volume: 141
Issue: 1
Pages: 205-13
Publication
First Author: Zhang RH
Year: 2013
Journal: Biochim Biophys Acta
Title: Inhibition of CYP2E1 attenuates chronic alcohol intake-induced myocardial contractile dysfunction and apoptosis.
Volume: 1832
Issue: 1
Pages: 128-41
Publication
First Author: Sohn OS
Year: 2001
Journal: Cancer Res
Title: Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol.
Volume: 61
Issue: 23
Pages: 8435-40
Publication
First Author: Tamási V
Year: 2003
Journal: Cell Biol Int
Title: Upregulation of CYP2e1 and CYP3a activities in histamine-deficient histidine decarboxylase gene targeted mice.
Volume: 27
Issue: 12
Pages: 1011-5
Publication
First Author: Cui X
Year: 2019
Journal: Front Med
Title: Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression levels.
Volume: 13
Issue: 1
Pages: 104-111
Publication
First Author: Leclercq IA
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice.
Volume: 268
Issue: 2
Pages: 337-44
Publication
First Author: Wang C
Year: 2014
Journal: J Cell Mol Med
Title: ATF4 deficiency protects hepatocytes from oxidative stress via inhibiting CYP2E1 expression.
Volume: 18
Issue: 1
Pages: 80-90
Publication
First Author: Boadas-Vaello P
Year: 2009
Journal: Toxicol Sci
Title: Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse.
Volume: 107
Issue: 2
Pages: 461-72
Publication
First Author: Zhang W
Year: 2011
Journal: FEBS J
Title: Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice.
Volume: 278
Issue: 9
Pages: 1484-92
Publication
First Author: Enriquez A
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Altered expression of hepatic CYP2E1 and CYP4A in obese, diabetic ob/ob mice, and fa/fa Zucker rats.
Volume: 255
Issue: 2
Pages: 300-6
Publication
First Author: Seree EM
Year: 1996
Journal: Biochem Biophys Res Commun
Title: High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks.
Volume: 219
Issue: 2
Pages: 429-34
Publication
First Author: Wang S
Year: 2015
Journal: Toxicol Sci
Title: N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer.
Volume: 144
Issue: 2
Pages: 393-405
Publication
First Author: Keating AF
Year: 2008
Journal: Toxicol Sci
Title: Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure.
Volume: 105
Issue: 2
Pages: 351-9
Publication
First Author: Lewis DF
Year: 1997
Journal: Toxicology
Title: Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and rationalization of CYP2E substrate specificity.
Volume: 118
Issue: 2-3
Pages: 93-113
Publication
First Author: Gong P
Year: 2006
Journal: J Biol Chem
Title: Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity.
Volume: 281
Issue: 21
Pages: 14573-9
Publication
First Author: Wu D
Year: 2009
Journal: Free Radic Biol Med
Title: Role of nitric oxide and nuclear factor-kappaB in the CYP2E1 potentiation of tumor necrosis factor alpha hepatotoxicity in mice.
Volume: 46
Issue: 4
Pages: 480-91
Publication
First Author: Zhou R
Year: 2014
Journal: Biochim Biophys Acta
Title: Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis.
Volume: 1840
Issue: 1
Pages: 209-18
Publication  
First Author: Wang X
Year: 2013
Journal: Free Radic Biol Med
Title: Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo.
Volume: 63
Pages: 175-86
Publication
First Author: Lu Y
Year: 2010
Journal: Free Radic Biol Med
Title: Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice.
Volume: 49
Issue: 9
Pages: 1406-16
Publication
First Author: Lu Y
Year: 2012
Journal: Toxicol Sci
Title: Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway.
Volume: 128
Issue: 2
Pages: 427-38
Publication
First Author: Bondoc FY
Year: 1999
Journal: Biochem Pharmacol
Title: Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice.
Volume: 58
Issue: 3
Pages: 461-3
Publication
First Author: Picklo MJ Sr
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Ethanol intoxication increases hepatic N-lysyl protein acetylation.
Volume: 376
Issue: 3
Pages: 615-9
Publication  
First Author: Freeman JE
Year: 1992
Journal: Biochem J
Title: cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse Cyp2e1.
Volume: 281 ( Pt 3)
Pages: 689-95
Publication
First Author: Ferdouse A
Year: 2022
Journal: PLoS One
Title: Alcohol induced hepatic retinoid depletion is associated with the induction of multiple retinoid catabolizing cytochrome P450 enzymes.
Volume: 17
Issue: 1
Pages: e0261675
Publication
First Author: Chen C
Year: 2008
Journal: J Biol Chem
Title: Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice.
Volume: 283
Issue: 8
Pages: 4543-59
Publication  
First Author: Abdelmegeed MA
Year: 2016
Journal: Free Radic Biol Med
Title: Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress.
Volume: 91
Pages: 188-202
Publication
First Author: Shi X
Year: 2012
Journal: J Biol Chem
Title: Identification of N-acetyltaurine as a novel metabolite of ethanol through metabolomics-guided biochemical analysis.
Volume: 287
Issue: 9
Pages: 6336-49
Publication  
First Author: Abdelmegeed MA
Year: 2017
Journal: Sci Rep
Title: Cytochrome P450-2E1 promotes fast food-mediated hepatic fibrosis.
Volume: 7
Pages: 39764
Publication
First Author: Gonzalez FJ
Year: 2005
Journal: Mutat Res
Title: Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1.
Volume: 569
Issue: 1-2
Pages: 101-10
Publication
First Author: Cheng J
Year: 2013
Journal: Toxicol Appl Pharmacol
Title: CYP2E1-dependent elevation of serum cholesterol, triglycerides, and hepatic bile acids by isoniazid.
Volume: 266
Issue: 2
Pages: 245-53
Publication
First Author: Wang X
Year: 2007
Journal: Free Radic Biol Med
Title: Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and -independent pathways.
Volume: 42
Issue: 7
Pages: 971-84
Publication
First Author: Wu D
Year: 2010
Journal: Free Radic Biol Med
Title: Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor alpha liver injury.
Volume: 49
Issue: 3
Pages: 348-60
Publication
First Author: Hoffler U
Year: 2003
Journal: J Pharmacol Exp Ther
Title: Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice.
Volume: 305
Issue: 2
Pages: 557-64
Publication
First Author: Park BC
Year: 1995
Journal: Pharmacology
Title: Cytochemical localization of the acetone-inducible cytochrome P-450 isoform, CYP2E1, in murine colonic epithelium.
Volume: 50
Issue: 6
Pages: 339-47
Publication
First Author: Tomasi ML
Year: 2018
Journal: FASEB J
Title: SUMOylation regulates cytochrome P450 2E1 expression and activity in alcoholic liver disease.
Volume: 32
Issue: 6
Pages: 3278-3288
Publication
First Author: Ghanayem BI
Year: 1999
Journal: J Pharmacol Exp Ther
Title: Role of cytochrome P-450 2E1 in methacrylonitrile metabolism and disposition.
Volume: 289
Issue: 2
Pages: 1054-9
Publication
First Author: Constan AA
Year: 1999
Journal: Toxicol Appl Pharmacol
Title: Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice.
Volume: 160
Issue: 2
Pages: 120-6
Publication
First Author: Wu D
Year: 2012
Journal: Free Radic Biol Med
Title: Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy.
Volume: 53
Issue: 6
Pages: 1346-57
Publication
First Author: Ghanayem BI
Year: 2005
Journal: Mutat Res
Title: Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect.
Volume: 578
Issue: 1-2
Pages: 284-97
Publication
First Author: Hoffler U
Year: 2005
Journal: Mutat Res
Title: Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice.
Volume: 572
Issue: 1-2
Pages: 58-72
Publication
First Author: El Hadri L
Year: 2005
Journal: Toxicol Appl Pharmacol
Title: Comparative metabolism of methacrylonitrile and acrylonitrile to cyanide using cytochrome P4502E1 and microsomal epoxide hydrolase-null mice.
Volume: 205
Issue: 2
Pages: 116-25
Publication
First Author: Evans MV
Year: 2010
Journal: Toxicol Appl Pharmacol
Title: Evaluation of two different metabolic hypotheses for dichloromethane toxicity using physiologically based pharmacokinetic modeling for in vivo inhalation gas uptake data exposure in female B6C3F1 mice.
Volume: 244
Issue: 3
Pages: 280-90
Publication
First Author: Das S
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis.
Volume: 305
Issue: 12
Pages: G950-63
Publication
First Author: Matsumoto A
Year: 2007
Journal: Alcohol
Title: Single-dose ethanol administration downregulates expression of cytochrome p450 2E1 mRNA in aldehyde dehydrogenase 2 knockout mice.
Volume: 41
Issue: 8
Pages: 587-9
Publication  
First Author: Lee GH
Year: 2016
Journal: Sci Rep
Title: Effect of BI-1 on insulin resistance through regulation of CYP2E1.
Volume: 6
Pages: 32229
Publication
First Author: Gonzalez FJ
Year: 1990
Journal: DNA Cell Biol
Title: Decreased Hnf-1 gene expression in mice homozygous for a 1.2-centiMorgan deletion on chromosome 7.
Volume: 9
Issue: 10
Pages: 771-6
Publication
First Author: Feng D
Year: 2014
Journal: J Immunol
Title: Acute and chronic effects of IL-22 on acetaminophen-induced liver injury.
Volume: 193
Issue: 5
Pages: 2512-8
Publication
First Author: Long N
Year: 2019
Journal: J Toxicol Sci
Title: Effects of infection of MRSA on the expression and activity of renal cytochrome P450s in mice.
Volume: 44
Issue: 4
Pages: 299-307
Publication
First Author: Seth RK
Year: 2013
Journal: Toxicol Sci
Title: Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice.
Volume: 134
Issue: 2
Pages: 291-303
Publication
First Author: Jugert FK
Year: 1994
Journal: J Invest Dermatol
Title: Multiple cytochrome P450 isozymes in murine skin: induction of P450 1A, 2B, 2E, and 3A by dexamethasone.
Volume: 102
Issue: 6
Pages: 970-5
Publication
First Author: Choudhary D
Year: 2005
Journal: Arch Biochem Biophys
Title: Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.
Volume: 436
Issue: 1
Pages: 50-61
Publication
First Author: Yang L
Year: 2012
Journal: Free Radic Biol Med
Title: Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver.
Volume: 53
Issue: 5
Pages: 1170-80
Publication
First Author: Seth RK
Year: 2014
Journal: Toxicol Appl Pharmacol
Title: CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis.
Volume: 274
Issue: 1
Pages: 42-54
Publication
First Author: Bae SH
Year: 2011
Journal: Hepatology
Title: Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver.
Volume: 53
Issue: 3
Pages: 945-53
Publication
First Author: Roe AL
Year: 1999
Journal: Int J Obes Relat Metab Disord
Title: Characterization of cytochrome P450 and glutathione S-transferase activity and expression in male and female ob/ob mice.
Volume: 23
Issue: 1
Pages: 48-53
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Davis JF
Year: 1993
Journal: J Biol Chem
Title: Mouse ethanol-inducible cytochrome P-450 (P450IIE1). Characterization of cDNA clones and testosterone induction in kidney tissue.
Volume: 268
Issue: 22
Pages: 16584-9
Publication
First Author: Vaglini F
Year: 2004
Journal: J Neurochem
Title: Involvement of cytochrome P450 2E1 in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse model of Parkinson's disease.
Volume: 91
Issue: 2
Pages: 285-98
Publication
First Author: Viaggi C
Year: 2009
Journal: Neuropharmacology
Title: MPTP-induced model of Parkinson's disease in cytochrome P450 2E1 knockout mice.
Volume: 56
Issue: 8
Pages: 1075-81