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Search results 1 to 100 out of 211 for Cyp46a1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
10858 | CYP46A1
Type: gene
Organism: human
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Gene
613111 | cyp46a1
Type: gene
Organism: frog, western clawed
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Gene
362782 | Cyp46a1
Type: gene
Organism: rat
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Gene
480432 | CYP46A1
Type: gene
Organism: dog, domestic
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Gene
453154 | CYP46A1
Type: gene
Organism: chimpanzee
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Gene
506438 | CYP46A1
Type: gene
Organism: cattle
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Gene
423450 | CYP46A1
Type: gene
Organism: chicken
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Gene
705843 | CYP46A1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR039983 | CYP46A1
Type: Family
Description: Cholesterol 24-hydroxylase (CYP46A1) is the neuronal-specific and rate-limiting enzyme for cholesterol conversion to 24S-hydroxycholesterol (24S-OHC) [, ]. It has a neuroprotective effect in Huntington's disease, a genetic disease that leads to many cellular dysfunctions, including abnormalities in cholesterol metabolism [, ].
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Protein Coding Gene
MGI:1341877 | Cyp46a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10377398 | J:56019
First Author: Lund EG
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain.
Volume: 96
Issue: 13
Pages: 7238-43
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Publication
30107216 | J:268841
     
First Author: Boussicault L
Year: 2018
Journal: Biochimie
Title: CYP46A1 protects against NMDA-mediated excitotoxicity in Huntington's disease: Analysis of lipid raft content.
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Publication
31063705 | J:293734
First Author: Petrov AM
Year: 2019
Journal: FASEB J
Title: The key genes, phosphoproteins, processes, and pathways affected by efavirenz-activated CYP46A1 in the amyloid-decreasing paradigm of efavirenz treatment.
Volume: 33
Issue: 8
Pages: 8782-8798
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Publication
38540675 | J:346698
 
First Author: Shu HJ
Year: 2024
Journal: Biomolecules
Title: Effects of Complete and Partial Loss of the 24S-Hydroxycholesterol-Generating Enzyme Cyp46a1 on Behavior and Hippocampal Transcription in Mouse.
Volume: 14
Issue: 3
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Protein
Q9WVK8
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
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Protein
A0A1Y7VM34
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: true
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Protein
Q3US73
Organism: Mus musculus/domesticus
Length: 500  
Fragment?: false
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Publication
14764421 | -
First Author: Björkhem I
Year: 2004
Journal: Arterioscler Thromb Vasc Biol
Title: Brain cholesterol: long secret life behind a barrier.
Volume: 24
Issue: 5
Pages: 806-15
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Publication
26912634 | -
First Author: Boussicault L
Year: 2016
Journal: Brain
Title: CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington's disease.
Volume: 139
Issue: Pt 3
Pages: 953-70
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Publication
37944529 | J:358291
First Author: Tsitsou-Kampeli A
Year: 2023
Journal: Cell Rep Med
Title: Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis.
Volume: 4
Issue: 11
Pages: 101278
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Publication
28655608 | J:249708
 
First Author: Mast N
Year: 2017
Journal: Neuropharmacology
Title: Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's disease.
Volume: 123
Pages: 465-476
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Publication
25084760 | J:325345
First Author: Moutinho M
Year: 2015
Journal: Mol Neurobiol
Title: Cholesterol 24S-Hydroxylase Overexpression Inhibits the Liver X Receptor (LXR) Pathway by Activating Small Guanosine Triphosphate-Binding Proteins (sGTPases) in Neuronal Cells.
Volume: 51
Issue: 3
Pages: 1489-503
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Publication
29073233 | J:248888
First Author: Mast N
Year: 2017
Journal: PLoS One
Title: Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1).
Volume: 12
Issue: 10
Pages: e0187168
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Publication
28190002 | J:241374
First Author: Mast N
Year: 2017
Journal: J Biol Chem
Title: Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum.
Volume: 292
Issue: 12
Pages: 4913-4924
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Publication
30448403 | J:270474
First Author: Saadane A
Year: 2019
Journal: Am J Pathol
Title: Retinal Vascular Abnormalities and Microglia Activation in Mice with Deficiency in Cytochrome P450 46A1-Mediated Cholesterol Removal.
Volume: 189
Issue: 2
Pages: 405-425
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Publication
22343944 | J:182508
First Author: Sodero AO
Year: 2012
Journal: EMBO J
Title: Cholesterol loss during glutamate-mediated excitotoxicity.
Volume: 31
Issue: 7
Pages: 1764-73
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Publication
32698250 | J:348010
First Author: El-Darzi N
Year: 2021
Journal: Br J Pharmacol
Title: 2-Hydroxypropyl-β-cyclodextrin reduces retinal cholesterol in wild-type and Cyp27a1(-/-) Cyp46a1(-/-) mice with deficiency in the oxysterol production.
Volume: 178
Issue: 16
Pages: 3220-3234
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Publication
14643015 | J:86935
First Author: Quan G
Year: 2003
Journal: Brain Res Dev Brain Res
Title: Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse.
Volume: 146
Issue: 1-2
Pages: 87-98
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Publication
22111624 | J:196553
First Author: Lorbek G
Year: 2012
Journal: FEBS J
Title: Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.
Volume: 279
Issue: 9
Pages: 1516-33
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Protein Coding Gene
MGP_CAROLIEiJ_G0018101 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020104 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020058 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020034 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019846 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1341877 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020489 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019388 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019813 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019930 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020005 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019147 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029858 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018951 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
18241055 | J:269548
First Author: Ramirez DM
Year: 2008
Journal: J Comp Neurol
Title: Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain.
Volume: 507
Issue: 5
Pages: 1676-93
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Publication
33051477 | J:299048
First Author: Nishi T
Year: 2020
Journal: Sci Rep
Title: Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice.
Volume: 10
Issue: 1
Pages: 17081
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Publication
12686551 | J:84116
First Author: Lund EG
Year: 2003
Journal: J Biol Chem
Title: Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover.
Volume: 278
Issue: 25
Pages: 22980-8
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Publication
19204288 | J:146447
First Author: Halford RW
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan.
Volume: 106
Issue: 9
Pages: 3502-6
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Publication
28346482 | J:245999
First Author: Sun MY
Year: 2017
Journal: PLoS One
Title: 24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation.
Volume: 12
Issue: 3
Pages: e0174416
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Publication
32132201 | J:286767
First Author: Yutuc E
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism.
Volume: 117
Issue: 11
Pages: 5749-5760
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Publication
24491562 | J:325508
First Author: Meljon A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse.
Volume: 446
Issue: 3
Pages: 768-74
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Publication
12810827 | J:85795
First Author: Xie C
Year: 2003
Journal: J Lipid Res
Title: Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration.
Volume: 44
Issue: 9
Pages: 1780-9
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3053374
Age: embryonic day 7.0
Specimen Label: E7
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3053374
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3053374
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3053374
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3053374
Age: postnatal week 8-12
Specimen Label: Heart
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3053374
Age: postnatal week 8-12
Specimen Label: Brain
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3053374
Age: postnatal week 8-12
Specimen Label: Spleen
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3053374
Age: postnatal week 8-12
Specimen Label: Lung
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3053374
Age: postnatal week 8-12
Specimen Label: Liver
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Absent
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3053374
Age: postnatal week 8-12
Specimen Label: S.M.
Detected: false
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3053374
Age: postnatal week 8-12
Specimen Label: Kidney
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3053314
Assay Type: RT-PCR
Annotation Date: 2004-10-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3053374
Age: postnatal week 8-12
Specimen Label: Testis
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:3691304
Assay Type: RT-PCR
Annotation Date: 2006-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3691309
Age: embryonic day 13.5
Image: 4
Specimen Label: 13.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3691304
Assay Type: RT-PCR
Annotation Date: 2006-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3691309
Age: embryonic day 13.5
Image: 4
Specimen Label: 13.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3691304
Assay Type: RT-PCR
Annotation Date: 2006-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3691309
Age: embryonic day 18.5
Image: 4
Specimen Label: 18.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3691304
Assay Type: RT-PCR
Annotation Date: 2006-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3691309
Age: embryonic day 18.5
Image: 4
Specimen Label: 18.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:3691304
Assay Type: RT-PCR
Annotation Date: 2006-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:3691309
Age: embryonic day 11.5
Image: 4
Specimen Label: 11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3691304
Assay Type: RT-PCR
Annotation Date: 2006-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:3691309
Age: embryonic day 11.5
Image: 4
Specimen Label: 11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3691304
Assay Type: RT-PCR
Annotation Date: 2006-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3691309
Age: embryonic day 20.5
Image: 4
Specimen Label: 20.5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:3691304
Assay Type: RT-PCR
Annotation Date: 2006-12-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:3691309
Age: embryonic day 20.5
Image: 4
Specimen Label: 20.5
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:6509656
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510249
Age: postnatal month 2
Image: 7
Specimen Label: WT 2MO
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6509656
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510249
Age: postnatal month 2
Image: 7
Specimen Label: DKO 2 MO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6509656
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510249
Age: postnatal month 7
Image: 7
Specimen Label: WT 7MO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6509656
Assay Type: RT-PCR
Annotation Date: 2021-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6510249
Age: postnatal month 7
Image: 7
Specimen Label: DKO 7MO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7385095
Assay Type: Western blot
Annotation Date: 2022-11-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7385093
Age: postnatal
Image: 1
Specimen Label: WT 1A7
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7385095
Assay Type: Western blot
Annotation Date: 2022-11-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7385093
Age: postnatal
Image: 1
Specimen Label: KO 1A7
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7385096
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7388168
Age: postnatal
Image: 1
Specimen Label: WT 1F11
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7385096
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7388168
Age: postnatal
Image: 1
Specimen Label: KO 1F11
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7385095
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7388169
Age: postnatal
Image: 1
Specimen Label: mouse
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7385096
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7388170
Age: postnatal
Image: 1
Specimen Label: mouse
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385095
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:7388171
Age: embryonic day 16.0
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385095
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284524
Stage: TS24
Assay Id: MGI:7388171
Age: embryonic day 16.0
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385095
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:7388171
Age: embryonic day 16.0
Image: 1
Specimen Label: KO
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385095
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284524
Stage: TS24
Assay Id: MGI:7388171
Age: embryonic day 16.0
Image: 1
Specimen Label: KO
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385096
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:7388172
Age: embryonic day 16.0
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385096
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284524
Stage: TS24
Assay Id: MGI:7388172
Age: embryonic day 16.0
Image: 1
Specimen Label: WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385096
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:7388172
Age: embryonic day 16.0
Image: 1
Specimen Label: KO
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385096
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284524
Stage: TS24
Assay Id: MGI:7388172
Age: embryonic day 16.0
Image: 1
Specimen Label: KO
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385097
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7388167
Age: postnatal
Image: 1
Specimen Label: WT 1F4
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385097
Assay Type: Western blot
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7388167
Age: postnatal
Image: 1
Specimen Label: KO 1F4
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7385095
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-29
Strength: Present
Sex: Female
Emaps: EMAPS:3558828
Pattern: Diffuse
Stage: TS28
Assay Id: MGI:7388174
Age: postnatal month 3
Image: 9A
Note: Expression was diffuse in the neuropil in all layers of the cortex.
Specimen Label: 9A
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7385095
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-29
Strength: Present
Sex: Female
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7388174
Age: postnatal month 3
Image: 9A
Note: Expression is in the somata of cortical neurons.
Specimen Label: 9A
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385096
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-29
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3526028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7388178
Age: postnatal month 3
Specimen Label: not shown WT
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7385095
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-29
Strength: Absent
Sex: Male
Emaps: EMAPS:3574428
Stage: TS28
Assay Id: MGI:7388174
Age: postnatal month 3
Image: 10A
Specimen Label: 10A
Detected: false
Specimen Num: 13
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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