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Search results 1 to 100 out of 458 for Dazl

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0.059s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: This entry includes human DAZL that belong to the DAZ family. DAZ family members include BOULE, DAZ-Like (DAZL) and DAZ. They are found almost exclusively in germ cells and are key players for germ cell development [, ]. They contain a highly conserved RNA-binding motif (RNA recognition motif; RRM) and a unique DAZ repeat []. Their RRM has been shown to bind 3'-UTR sequences of target mRNAs. They may be involved in regulation of mRNA translation [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Pan HA
Year: 2008
Journal: Fertil Steril
Title: DAZL protein expression in mouse preimplantation embryo.
Volume: 89
Issue: 5 Suppl
Pages: 1324-7
Publication
First Author: Li H
Year: 2019
Journal: Natl Sci Rev
Title: DAZL is a master translational regulator of murine spermatogenesis.
Volume: 6
Issue: 3
Pages: 455-468
Protein
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
Publication
First Author: Schrans-Stassen BH
Year: 2001
Journal: Biol Reprod
Title: Nature of the spermatogenic arrest in Dazl -/- mice.
Volume: 65
Issue: 3
Pages: 771-6
Publication
First Author: Vogel T
Year: 2002
Journal: Mol Hum Reprod
Title: Partial rescue of the Dazl knockout mouse by the human DAZL gene.
Volume: 8
Issue: 9
Pages: 797-804
Publication
First Author: Fu XF
Year: 2015
Journal: Int J Biol Sci
Title: DAZ Family Proteins, Key Players for Germ Cell Development.
Volume: 11
Issue: 10
Pages: 1226-35
Publication
First Author: Sousa Martins JP
Year: 2016
Journal: J Cell Sci
Title: DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.
Volume: 129
Issue: 6
Pages: 1271-82
Protein
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
Publication
First Author: Zagore LL
Year: 2018
Journal: Cell Rep
Title: DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.
Volume: 25
Issue: 5
Pages: 1225-1240.e6
Publication
First Author: Rilianawati
Year: 2003
Journal: Reproduction
Title: Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.
Volume: 126
Issue: 5
Pages: 599-604
Publication
First Author: Kee K
Year: 2009
Journal: Nature
Title: Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation.
Volume: 462
Issue: 7270
Pages: 222-5
Publication
First Author: Yen PH
Year: 2004
Journal: Int J Androl
Title: Putative biological functions of the DAZ family.
Volume: 27
Issue: 3
Pages: 125-9
Publication    
First Author: Mikedis MM
Year: 2020
Journal: Elife
Title: DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.
Volume: 9
Publication
First Author: Kim B
Year: 2012
Journal: Development
Title: DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.
Volume: 139
Issue: 3
Pages: 568-78
Publication
First Author: Collier B
Year: 2005
Journal: EMBO J
Title: The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.
Volume: 24
Issue: 14
Pages: 2656-66
Publication
First Author: Chen HH
Year: 2014
Journal: Stem Cell Reports
Title: DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells.
Volume: 3
Issue: 5
Pages: 892-904
Publication
First Author: Yang CR
Year: 2020
Journal: Nat Commun
Title: The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.
Volume: 11
Issue: 1
Pages: 1399
Publication
First Author: Slee R
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.
Volume: 96
Issue: 14
Pages: 8040-5
Publication
First Author: Maratou K
Year: 2004
Journal: Mol Reprod Dev
Title: Expression profiling of the developing testis in wild-type and Dazl knockout mice.
Volume: 67
Issue: 1
Pages: 26-54
Publication
First Author: Fukuda K
Year: 2018
Journal: PLoS Genet
Title: Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.
Volume: 14
Issue: 6
Pages: e1007436
Publication  
First Author: Kato Y
Year: 2016
Journal: Nat Commun
Title: Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells.
Volume: 7
Pages: 11272
Publication
First Author: Lin Y
Year: 2005
Journal: Dev Biol
Title: Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.
Volume: 288
Issue: 2
Pages: 309-16
Publication
First Author: McNeilly JR
Year: 2011
Journal: Biol Reprod
Title: Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.
Volume: 85
Issue: 3
Pages: 584-93
Publication
First Author: Lee KH
Year: 2006
Journal: EMBO J
Title: Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.
Volume: 25
Issue: 18
Pages: 4263-70
Publication
First Author: McNeilly JR
Year: 2000
Journal: Endocrinology
Title: Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.
Volume: 141
Issue: 11
Pages: 4284-94
Publication
First Author: He J
Year: 2013
Journal: PLoS One
Title: A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.
Volume: 8
Issue: 9
Pages: e73996
Publication
First Author: Haston KM
Year: 2009
Journal: PLoS One
Title: Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.
Volume: 4
Issue: 5
Pages: e5654
GXD Expression      
Probe: MGI:5629360
Assay Type: Western blot
Annotation Date: 2015-04-13
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5629362
Age: postnatal adult
Specimen Label: Dazl KO
Detected: false
Specimen Num: 3
Publication
First Author: Jenkins HT
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.
Volume: 108
Issue: 45
Pages: 18266-71
Publication
First Author: Jiao X
Year: 2002
Journal: Biol Reprod
Title: Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.
Volume: 66
Issue: 2
Pages: 475-85
Publication
First Author: Moore FL
Year: 2004
Journal: Genomics
Title: Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.
Volume: 83
Issue: 5
Pages: 834-43
Publication      
First Author: Garbers DL
Year: 2009
Journal: MGI Direct Data Submission
Title: Generation of a Dazl transgenic reporter allele
Publication
First Author: Xu EY
Year: 2007
Journal: Mol Reprod Dev
Title: A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.
Volume: 74
Issue: 7
Pages: 912-21
Publication
First Author: Guzeloglu-Kayisli O
Year: 2012
Journal: Biochem J
Title: Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.
Volume: 446
Issue: 1
Pages: 47-58
Publication
First Author: Reynolds N
Year: 2007
Journal: RNA
Title: Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.
Volume: 13
Issue: 7
Pages: 974-81
Publication
First Author: Koubova J
Year: 2014
Journal: PLoS Genet
Title: Retinoic acid activates two pathways required for meiosis in mice.
Volume: 10
Issue: 8
Pages: e1004541
Publication
First Author: Fu XF
Year: 2017
Journal: Histochem Cell Biol
Title: The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.
Volume: 148
Issue: 1
Pages: 61-72
Publication  
First Author: Liu W
Year: 2017
Journal: Nat Commun
Title: BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis.
Volume: 8
Pages: 14182
Publication
First Author: Giese S
Year: 2012
Journal: Dis Model Mech
Title: Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.
Volume: 5
Issue: 6
Pages: 895-913
Publication
First Author: Maatouk DM
Year: 2006
Journal: Development
Title: DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages.
Volume: 133
Issue: 17
Pages: 3411-8
Publication
First Author: Wang Q
Year: 2013
Journal: Stem Cell Res
Title: GASZ promotes germ cell derivation from embryonic stem cells.
Volume: 11
Issue: 2
Pages: 845-60
Publication
First Author: Saunders PT
Year: 2003
Journal: Reproduction
Title: Absence of mDazl produces a final block on germ cell development at meiosis.
Volume: 126
Issue: 5
Pages: 589-97
Publication
First Author: Olive V
Year: 2007
Journal: Development
Title: PU.1 (Sfpi1), a pleiotropic regulator expressed from the first embryonic stages with a crucial function in germinal progenitors.
Volume: 134
Issue: 21
Pages: 3815-25
Publication
First Author: Gill ME
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cells.
Volume: 108
Issue: 18
Pages: 7443-8
Publication
First Author: Chen J
Year: 2011
Journal: Genes Dev
Title: Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition.
Volume: 25
Issue: 7
Pages: 755-66
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Elliott DJ
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.
Volume: 97
Issue: 11
Pages: 5717-22
Publication
First Author: Maiwald R
Year: 1996
Journal: Mamm Genome
Title: Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.
Volume: 7
Issue: 8
Pages: 628
Publication
First Author: Cooke HJ
Year: 1996
Journal: Hum Mol Genet
Title: A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.
Volume: 5
Issue: 4
Pages: 513-6
Publication
First Author: Reijo R
Year: 1996
Journal: Genomics
Title: Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.
Volume: 35
Issue: 2
Pages: 346-52
Publication
First Author: Ruggiu M
Year: 1997
Journal: Nature
Title: The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.
Volume: 389
Issue: 6646
Pages: 73-7
Publication
First Author: Ruggiu M
Year: 2000
Journal: Gene
Title: In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.
Volume: 252
Issue: 1-2
Pages: 119-26
Publication
First Author: Shan Z
Year: 1996
Journal: Hum Mol Genet
Title: A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.
Volume: 5
Issue: 12
Pages: 2005-11
Publication
First Author: Yen PH
Year: 1996
Journal: Hum Mol Genet
Title: The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.
Volume: 5
Issue: 12
Pages: 2013-7
Publication
First Author: Seboun E
Year: 1997
Journal: Genomics
Title: Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.
Volume: 41
Issue: 2
Pages: 227-35
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:2156424
Age: embryonic day 15.0
Image: 3
Specimen Label: E15
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797225
Stage: TS25
Assay Id: MGI:2156424
Age: embryonic day 17.0
Image: 3
Specimen Label: E17
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:2156424
Age: postnatal newborn
Image: 3
Specimen Label: Day 0
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:2156424
Age: postnatal day 3
Image: 3
Specimen Label: Day 3
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal day 7
Image: 3
Specimen Label: Day 7
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal day 14
Image: 3
Specimen Label: Day 14
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal day 20
Image: 3
Specimen Label: Day 20
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal adult
Image: 3
Specimen Label: Adult
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal
Image: 3
Specimen Label: W/W
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 6
Image: 5
Specimen Label: day 6
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 8
Image: 5
Specimen Label: day 8
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 13
Image: 5
Specimen Label: day 13
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 19
Image: 5
Specimen Label: day 19
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 27
Image: 5
Specimen Label: day 27
Detected: true
Specimen Num: 5