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Search results 1 to 100 out of 461 for Dazl

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Hits by Category

Hits by Strain

Type Details Score
Gene
1618 | DAZL
Type: gene
Organism: human
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Gene
394676 | dazl
Type: gene
Organism: frog, western clawed
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Gene
106992263 | DAZL
Type: gene
Organism: macaque, rhesus
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Gene
680486 | Dazl
Type: gene
Organism: rat
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Gene
460209 | DAZL
Type: gene
Organism: chimpanzee
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Gene
477055 | DAZL
Type: gene
Organism: dog, domestic
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Gene
530116 | DAZL
Type: gene
Organism: cattle
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Gene
374054 | DAZL
Type: gene
Organism: chicken
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Gene
58039 | dazl
Type: gene
Organism: zebrafish
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Protein Domain
IPR034779 | DAZL
Type: Family
Description: This entry includes human DAZL that belong to the DAZ family. DAZ family members include BOULE, DAZ-Like (DAZL) and DAZ. They are found almost exclusively in germ cells and are key players for germ cell development [, ]. They contain a highly conserved RNA-binding motif (RNA recognition motif; RRM) and a unique DAZ repeat []. Their RRM has been shown to bind 3'-UTR sequences of target mRNAs. They may be involved in regulation of mRNA translation [].
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Protein Coding Gene
MGI:1342328 | Dazl
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17761180 | J:136904
First Author: Pan HA
Year: 2008
Journal: Fertil Steril
Title: DAZL protein expression in mouse preimplantation embryo.
Volume: 89
Issue: 5 Suppl
Pages: 1324-7
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Publication
31355046 | J:277616
First Author: Li H
Year: 2019
Journal: Natl Sci Rev
Title: DAZL is a master translational regulator of murine spermatogenesis.
Volume: 6
Issue: 3
Pages: 455-468
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Protein
A0A3B2WD26
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
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Publication
11514340 | J:71070
First Author: Schrans-Stassen BH
Year: 2001
Journal: Biol Reprod
Title: Nature of the spermatogenic arrest in Dazl -/- mice.
Volume: 65
Issue: 3
Pages: 771-6
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Publication
12200456 | J:102354
First Author: Vogel T
Year: 2002
Journal: Mol Hum Reprod
Title: Partial rescue of the Dazl knockout mouse by the human DAZL gene.
Volume: 8
Issue: 9
Pages: 797-804
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Publication
26327816 | -
First Author: Fu XF
Year: 2015
Journal: Int J Biol Sci
Title: DAZ Family Proteins, Key Players for Germ Cell Development.
Volume: 11
Issue: 10
Pages: 1226-35
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Publication
26826184 | J:246427
First Author: Sousa Martins JP
Year: 2016
Journal: J Cell Sci
Title: DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation.
Volume: 129
Issue: 6
Pages: 1271-82
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Protein
Q64368
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Protein
Q499F1
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Protein
Q3TUC3
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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Publication
30380414 | J:270404
First Author: Zagore LL
Year: 2018
Journal: Cell Rep
Title: DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions.
Volume: 25
Issue: 5
Pages: 1225-1240.e6
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Publication
14611632 | J:87151
First Author: Rilianawati
Year: 2003
Journal: Reproduction
Title: Spermatogenesis in testes of Dazl null mice after transplantation of wild-type germ cells.
Volume: 126
Issue: 5
Pages: 599-604
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Publication
19865085 | -
First Author: Kee K
Year: 2009
Journal: Nature
Title: Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation.
Volume: 462
Issue: 7270
Pages: 222-5
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Publication
15139965 | -
First Author: Yen PH
Year: 2004
Journal: Int J Androl
Title: Putative biological functions of the DAZ family.
Volume: 27
Issue: 3
Pages: 125-9
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Publication
32686646 | J:324076
   
First Author: Mikedis MM
Year: 2020
Journal: Elife
Title: DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors.
Volume: 9
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Publication
22223682 | J:179729
First Author: Kim B
Year: 2012
Journal: Development
Title: DAZL is essential for stress granule formation implicated in germ cell survival upon heat stress.
Volume: 139
Issue: 3
Pages: 568-78
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Publication
16001084 | J:114722
First Author: Collier B
Year: 2005
Journal: EMBO J
Title: The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells.
Volume: 24
Issue: 14
Pages: 2656-66
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Publication
25418731 | J:316527
First Author: Chen HH
Year: 2014
Journal: Stem Cell Reports
Title: DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells.
Volume: 3
Issue: 5
Pages: 892-904
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Publication
32170089 | J:286388
First Author: Yang CR
Year: 2020
Journal: Nat Commun
Title: The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation.
Volume: 11
Issue: 1
Pages: 1399
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Publication
10393944 | J:120235
First Author: Slee R
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A human DAZ transgene confers partial rescue of the mouse Dazl null phenotype.
Volume: 96
Issue: 14
Pages: 8040-5
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Publication
14648873 | J:109709
First Author: Maratou K
Year: 2004
Journal: Mol Reprod Dev
Title: Expression profiling of the developing testis in wild-type and Dazl knockout mice.
Volume: 67
Issue: 1
Pages: 26-54
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Publication
29883445 | J:263627
First Author: Fukuda K
Year: 2018
Journal: PLoS Genet
Title: Requirement of the 3'-UTR-dependent suppression of DAZL in oocytes for pre-implantation mouse development.
Volume: 14
Issue: 6
Pages: e1007436
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Publication
27072294 | J:230563
 
First Author: Kato Y
Year: 2016
Journal: Nat Commun
Title: Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells.
Volume: 7
Pages: 11272
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Publication
16310179 | J:104848
First Author: Lin Y
Year: 2005
Journal: Dev Biol
Title: Dazl deficiency leads to embryonic arrest of germ cell development in XY C57BL/6 mice.
Volume: 288
Issue: 2
Pages: 309-16
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Publication
21270429 | J:176706
First Author: McNeilly JR
Year: 2011
Journal: Biol Reprod
Title: Decreased oocyte DAZL expression in mice results in increased litter size by modulating follicle-stimulating hormone-induced follicular growth.
Volume: 85
Issue: 3
Pages: 584-93
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Publication
16946704 | J:200430
First Author: Lee KH
Year: 2006
Journal: EMBO J
Title: Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAs.
Volume: 25
Issue: 18
Pages: 4263-70
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Publication
11089564 | J:65576
First Author: McNeilly JR
Year: 2000
Journal: Endocrinology
Title: Loss of oocytes in Dazl knockout mice results in maintained ovarian steroidogenic function but altered gonadotropin secretion in adult animals.
Volume: 141
Issue: 11
Pages: 4284-94
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Publication
24086306 | J:207748
First Author: He J
Year: 2013
Journal: PLoS One
Title: A developmental stage-specific switch from DAZL to BOLL occurs during fetal oogenesis in humans, but not mice.
Volume: 8
Issue: 9
Pages: e73996
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Publication
19468308 | J:148836
First Author: Haston KM
Year: 2009
Journal: PLoS One
Title: Dazl functions in maintenance of pluripotency and genetic and epigenetic programs of differentiation in mouse primordial germ cells in vivo and in vitro.
Volume: 4
Issue: 5
Pages: e5654
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GXD Expression
GXD Expression
     
Probe: MGI:5629360
Assay Type: Western blot
Annotation Date: 2015-04-13
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5629362
Age: postnatal adult
Specimen Label: Dazl KO
Detected: false
Specimen Num: 3
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Publication
22021443 | J:180264
First Author: Jenkins HT
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Kinked β-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.
Volume: 108
Issue: 45
Pages: 18266-71
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Publication
11804965 | J:74010
First Author: Jiao X
Year: 2002
Journal: Biol Reprod
Title: Identification of target messenger RNA substrates for the murine deleted in azoospermia-like RNA-binding protein.
Volume: 66
Issue: 2
Pages: 475-85
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Publication
15081113 | J:265619
First Author: Moore FL
Year: 2004
Journal: Genomics
Title: Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells.
Volume: 83
Issue: 5
Pages: 834-43
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Publication
- | J:147188
     
First Author: Garbers DL
Year: 2009
Journal: MGI Direct Data Submission
Title: Generation of a Dazl transgenic reporter allele
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Publication
17219433 | J:123531
First Author: Xu EY
Year: 2007
Journal: Mol Reprod Dev
Title: A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.
Volume: 74
Issue: 7
Pages: 912-21
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Publication
17526644 | J:136465
First Author: Reynolds N
Year: 2007
Journal: RNA
Title: Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl.
Volume: 13
Issue: 7
Pages: 974-81
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Publication
22621333 | J:187525
First Author: Guzeloglu-Kayisli O
Year: 2012
Journal: Biochem J
Title: Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.
Volume: 446
Issue: 1
Pages: 47-58
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Publication
25102060 | J:215225
First Author: Koubova J
Year: 2014
Journal: PLoS Genet
Title: Retinoic acid activates two pathways required for meiosis in mice.
Volume: 10
Issue: 8
Pages: e1004541
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Publication
28235998 | J:264399
First Author: Fu XF
Year: 2017
Journal: Histochem Cell Biol
Title: The epigenetic modifications and the anterior to posterior characterization of meiotic entry during mouse oogenesis.
Volume: 148
Issue: 1
Pages: 61-72
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Publication
28128212 | J:244859
 
First Author: Liu W
Year: 2017
Journal: Nat Commun
Title: BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis.
Volume: 8
Pages: 14182
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Publication
22699423 | J:191905
First Author: Giese S
Year: 2012
Journal: Dis Model Mech
Title: Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice.
Volume: 5
Issue: 6
Pages: 895-913
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Publication
16887828 | J:112224
First Author: Maatouk DM
Year: 2006
Journal: Development
Title: DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages.
Volume: 133
Issue: 17
Pages: 3411-8
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Publication
14611631 | J:87152
First Author: Saunders PT
Year: 2003
Journal: Reproduction
Title: Absence of mDazl produces a final block on germ cell development at meiosis.
Volume: 126
Issue: 5
Pages: 589-97
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Publication
17913791 | J:126326
First Author: Olive V
Year: 2007
Journal: Development
Title: PU.1 (Sfpi1), a pleiotropic regulator expressed from the first embryonic stages with a crucial function in germinal progenitors.
Volume: 134
Issue: 21
Pages: 3815-25
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Publication
23816659 | J:316493
First Author: Wang Q
Year: 2013
Journal: Stem Cell Res
Title: GASZ promotes germ cell derivation from embryonic stem cells.
Volume: 11
Issue: 2
Pages: 845-60
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Publication
21504946 | J:172213
First Author: Gill ME
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cells.
Volume: 108
Issue: 18
Pages: 7443-8
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Publication
21460039 | J:170300
First Author: Chen J
Year: 2011
Journal: Genes Dev
Title: Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition.
Volume: 25
Issue: 7
Pages: 755-66
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Protein Coding Gene
MGP_CAROLIEiJ_G0021735 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023881 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023841 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1342328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024286 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023582 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023705 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023152 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020724 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022647 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10823932 | J:230391
First Author: Elliott DJ
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.
Volume: 97
Issue: 11
Pages: 5717-22
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Publication
8679003 | J:34796
First Author: Maiwald R
Year: 1996
Journal: Mamm Genome
Title: Isolation of a mouse homolog of the human DAZ (Deleted in Azoospermia) gene.
Volume: 7
Issue: 8
Pages: 628
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Publication
8845845 | J:32990
First Author: Cooke HJ
Year: 1996
Journal: Hum Mol Genet
Title: A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads.
Volume: 5
Issue: 4
Pages: 513-6
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Publication
8661148 | J:34143
First Author: Reijo R
Year: 1996
Journal: Genomics
Title: Mouse autosomal homolog of DAZ, a candidate male sterility gene in humans, is expressed in male germ cells before and after puberty.
Volume: 35
Issue: 2
Pages: 346-52
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Publication
9288969 | J:42612
First Author: Ruggiu M
Year: 1997
Journal: Nature
Title: The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis.
Volume: 389
Issue: 6646
Pages: 73-7
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Publication
10903443 | J:143695
First Author: Ruggiu M
Year: 2000
Journal: Gene
Title: In vivo and in vitro analysis of homodimerisation activity of the mouse Dazl1 protein.
Volume: 252
Issue: 1-2
Pages: 119-26
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Publication
8968755 | J:37122
First Author: Shan Z
Year: 1996
Journal: Hum Mol Genet
Title: A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene boule is autosomal and expressed only in the human male gonad.
Volume: 5
Issue: 12
Pages: 2005-11
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Publication
8968756 | J:37965
First Author: Yen PH
Year: 1996
Journal: Hum Mol Genet
Title: The human autosomal gene DAZLA: testis specificity and a candidate for male infertility.
Volume: 5
Issue: 12
Pages: 2013-7
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Publication
9143498 | J:39835
First Author: Seboun E
Year: 1997
Journal: Genomics
Title: Gene sequence, localization, and evolutionary conservation of DAZLA, a candidate male sterility gene.
Volume: 41
Issue: 2
Pages: 227-35
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:2156424
Age: embryonic day 15.0
Image: 3
Specimen Label: E15
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797225
Stage: TS25
Assay Id: MGI:2156424
Age: embryonic day 17.0
Image: 3
Specimen Label: E17
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:2156424
Age: postnatal newborn
Image: 3
Specimen Label: Day 0
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:2156424
Age: postnatal day 3
Image: 3
Specimen Label: Day 3
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal day 7
Image: 3
Specimen Label: Day 7
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal day 14
Image: 3
Specimen Label: Day 14
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal day 20
Image: 3
Specimen Label: Day 20
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal adult
Image: 3
Specimen Label: Adult
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:2156181
Assay Type: RT-PCR
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156424
Age: postnatal
Image: 3
Specimen Label: W/W
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 6
Image: 5
Specimen Label: day 6
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 8
Image: 5
Specimen Label: day 8
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 13
Image: 5
Specimen Label: day 13
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 19
Image: 5
Specimen Label: day 19
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2156443
Assay Type: Western blot
Annotation Date: 2002-01-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2156444
Age: postnatal day 27
Image: 5
Specimen Label: day 27
Detected: true
Specimen Num: 5
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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