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Search results 1 to 100 out of 103 for Dcaf7

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0.045s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Xiang J
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome.
Volume: 114
Issue: 7
Pages: E1224-E1233
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:7387140
Assay Type: RT-PCR
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:7388121
Age: embryonic day 2.0
Specimen Label: 4-cell
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:7387140
Assay Type: RT-PCR
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160331
Stage: TS01
Assay Id: MGI:7388121
Age: embryonic day 0.5
Specimen Label: zygote
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:7387140
Assay Type: RT-PCR
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318653
Stage: TS03
Assay Id: MGI:7388121
Age: embryonic day 2.5
Specimen Label: 8-cell
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:7387140
Assay Type: RT-PCR
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360354
Stage: TS04
Assay Id: MGI:7388121
Age: embryonic day 3.5
Specimen Label: blast
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:7387140
Assay Type: RT-PCR
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160404
Stage: TS04
Assay Id: MGI:7388121
Age: embryonic day 3.0
Specimen Label: morula
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:7387140
Assay Type: RT-PCR
Annotation Date: 2022-11-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:7388121
Age: embryonic day 1.0
Specimen Label: 2-cell
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4416926
Assay Type: RNA in situ
Annotation Date: 2024-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7621103
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3691828
Assay Type: RNA in situ
Annotation Date: 2006-12-26
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1640517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3691831
Age: embryonic day 10.5
Note: Uniform expression along the antero-posterior axis.
Specimen Label: 6A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4416926
Assay Type: RNA in situ
Annotation Date: 2024-04-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7621103
Age: embryonic day 14.5
Note: Cortical plate expression was greater than in the subventricular zone.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4416926
Assay Type: RNA in situ
Annotation Date: 2011-02-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4881827
Age: embryonic day 14.5
Image: 1
Note: Expression is present in all tissues and structures.
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6170966
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191555
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Wdr68
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6170966
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191555
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Wdr68
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6170966
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191555
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Wdr68
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6170966
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191555
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Wdr68
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6170966
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191555
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Wdr68
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6170966
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191555
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Wdr68
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6170966
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191555
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Wdr68
Detected: true
Specimen Num: 7
Publication
First Author: Morita K
Year: 2006
Journal: J Dermatol Sci
Title: HAN11 binds mDia1 and controls GLI1 transcriptional activity.
Volume: 44
Issue: 1
Pages: 11-20
Publication
First Author: Stoller JZ
Year: 2010
Journal: Exp Biol Med (Maywood)
Title: Ash2l interacts with Tbx1 and is required during early embryogenesis.
Volume: 235
Issue: 5
Pages: 569-76
Publication  
First Author: Zhang YL
Year: 2018
Journal: EMBO J
Title: DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development.
Volume: 37
Issue: 18
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: DDB1 and CUL4 associated factor 7; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication  
First Author: Paffendorf BAM
Year: 2020
Journal: PeerJ
Title: TRANSPARENT TESTA GLABRA 1 participates in flowering time regulation in Arabidopsis thaliana.
Volume: 8
Pages: e8303
Publication  
First Author: Nissen RM
Year: 2006
Journal: BMC Dev Biol
Title: A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression.
Volume: 6
Pages: 28
Publication
First Author: Park J
Year: 2013
Journal: Exp Neurobiol
Title: New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down Syndrome.
Volume: 22
Issue: 4
Pages: 244-8
Publication
First Author: Wu JF
Year: 2008
Journal: Plant Physiol
Title: Two new clock proteins, LWD1 and LWD2, regulate Arabidopsis photoperiodic flowering.
Volume: 148
Issue: 2
Pages: 948-59
Publication
First Author: Leslie EJ
Year: 2016
Journal: Hum Mol Genet
Title: A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13.
Volume: 25
Issue: 13
Pages: 2862-2872
Protein Domain
Type: Family
Description: This entry represents a group of WD repeat-containing proteins, including DCAF7 from animals, LWD1/2/TTG1 from Arabidopsis and YPL247C from budding yeasts. In general, WD40 repeat domain-containing proteins are scaffolding elements for the assembly of multi-subunit protein complexes. DCAF7, also known as WDR68, interacts with Dual-specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A, a Down's syndrome-associated protein kinase) []and is required for Endothelin-1 (EDN1) signalling []. It also acts as a DDB1- and CUL4-associated factor []. Mutations in the DCAF7 gene have been linked to cleft lip with or without cleft palate (CL/P) []. In Arabidopsis, LWD1 and LWD2 serve as clock proteins involved in photoperiod flowering control []. TRANSPARENT TESTA GLABRA 1 (TTG1) is a regulator of early developmental traits and is also involved in flowering time regulation [].
Publication
First Author: Jin J
Year: 2006
Journal: Mol Cell
Title: A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.
Volume: 23
Issue: 5
Pages: 709-21
Publication
First Author: Xu J
Year: 2023
Journal: Cancer Res
Title: MEN1 Degradation Induced by Neddylation and the CUL4B-DCAF7 Axis Promotes Pancreatic Neuroendocrine Tumor Progression.
Volume: 83
Issue: 13
Pages: 2226-2247