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Search results 1 to 100 out of 114 for Ddx41

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
51428 | DDX41
Type: gene
Organism: human
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Gene
462310 | DDX41
Type: gene
Organism: chimpanzee
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Gene
505276 | DDX41
Type: gene
Organism: cattle
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Gene
427630 | DDX41
Type: gene
Organism: chicken
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Gene
394020 | ddx41
Type: gene
Organism: zebrafish
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Gene
700742 | DDX41
Type: gene
Organism: macaque, rhesus
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Gene
100491281 | ddx41
Type: gene
Organism: frog, western clawed
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Gene
314336 | Ddx41
Type: gene
Organism: rat
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Gene
479274 | DDX41
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1920185 | Ddx41
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
34473945 | J:326963
First Author: Chlon TM
Year: 2021
Journal: Cell Stem Cell
Title: Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia.
Volume: 28
Issue: 11
Pages: 1966-1981.e6
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Publication
36229594 | J:342740
First Author: Shinriki S
Year: 2022
Journal: Leukemia
Title: DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells.
Volume: 36
Issue: 11
Pages: 2605-2620
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Publication
35303436 | J:326717
First Author: Ma J
Year: 2022
Journal: Stem Cell Reports
Title: DDX41 is needed for pre- and postnatal hematopoietic stem cell differentiation in mice.
Volume: 17
Issue: 4
Pages: 879-893
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Publication
21892174 | J:176439
First Author: Zhang Z
Year: 2011
Journal: Nat Immunol
Title: The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells.
Volume: 12
Issue: 10
Pages: 959-65
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Publication
25704810 | J:324776
First Author: Lee KG
Year: 2015
Journal: Cell Rep
Title: Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.
Volume: 10
Issue: 7
Pages: 1055-65
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Publication
29871919 | J:265023
 
First Author: Stavrou S
Year: 2018
Journal: MBio
Title: DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection.
Volume: 9
Issue: 3
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Publication
23142775 | J:200472
First Author: Parvatiyar K
Year: 2012
Journal: Nat Immunol
Title: The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.
Volume: 13
Issue: 12
Pages: 1155-61
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Publication
23222971 | J:192552
First Author: Zhang Z
Year: 2013
Journal: Nat Immunol
Title: The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA.
Volume: 14
Issue: 2
Pages: 172-8
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Protein Coding Gene
MGP_CAROLIEiJ_G0018568 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020602 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020556 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020534 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020552 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1920185 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019865 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020311 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020413 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019621 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019633 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019448 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692035
Age: postnatal adult
Image: TCP_2460006
Specimen Label: TCP_2460006
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692035
Age: postnatal adult
Image: TCP_2460007
Specimen Label: TCP_2460007
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692035
Age: postnatal adult
Image: TCP_2460003
Specimen Label: TCP_2460003
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692035
Age: postnatal adult
Image: TCP_2460004
Specimen Label: TCP_2460004
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692035
Age: postnatal adult
Image: TCP_2460005
Specimen Label: TCP_2460005
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_09
Specimen Label: euxassay_000473_09
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_10
Specimen Label: euxassay_000473_10
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_11
Specimen Label: euxassay_000473_11
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_12
Specimen Label: euxassay_000473_12
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_15
Specimen Label: euxassay_000473_15
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_16
Specimen Label: euxassay_000473_16
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_17
Specimen Label: euxassay_000473_17
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_09
Specimen Label: euxassay_000473_09
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_10
Specimen Label: euxassay_000473_10
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_11
Specimen Label: euxassay_000473_11
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_15
Specimen Label: euxassay_000473_15
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_16
Specimen Label: euxassay_000473_16
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
 
Probe: MGI:532810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4824271
Age: embryonic day 14.5
Image: euxassay_000473_17
Specimen Label: euxassay_000473_17
Detected: true
Specimen Num: 7
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Publication
16595651 | J:113459
First Author: Nagamori I
Year: 2006
Journal: J Biol Chem
Title: Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.
Volume: 281
Issue: 22
Pages: 15073-81
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Probable ATP-dependent RNA helicase DDX41
Type: chain
End: 622
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Protein
Q91VN6
Organism: Mus musculus/domesticus
Length: 622  
Fragment?: false
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Publication
25920683 | -
First Author: Polprasert C
Year: 2015
Journal: Cancer Cell
Title: Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.
Volume: 27
Issue: 5
Pages: 658-70
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Publication
27502187 | -
First Author: Jiang Y
Year: 2017
Journal: Protein Cell
Title: The emerging roles of the DDX41 protein in immunity and diseases.
Volume: 8
Issue: 2
Pages: 83-89
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Gene
6208 | RPS14
Type: gene
Organism: human
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Protein Domain
IPR044113 | DEADc_DDX41
Type: Domain
Description: DDX41 interacts with several spliceosomal proteins and may recognise the bacterial second messengers cyclic di-GMP and cyclic di-AMP, resulting in the induction of genes involved in the innate immune response []. DDX41 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. Mutations of the DDX41 gene cause myeloproliferative/lymphoproliferative neoplasms, familial (MPLPF) [].This entry represents the DEAD-box domain of DDX41. It contains the ATP-binding region [].
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