Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
763
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
763
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
MacNair L |
Year: |
2016 |
Journal: |
Brain |
Title: |
MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. |
Volume: |
139 |
Issue: |
Pt 1 |
Pages: |
86-100 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
926
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
227
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
472
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
410
|
Fragment?: |
false |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Ferrage F |
Year: |
2012 |
Journal: |
Structure |
Title: |
Structure and dynamics of the second CARD of human RIG-I provide mechanistic insights into regulation of RIG-I activation. |
Volume: |
20 |
Issue: |
12 |
Pages: |
2048-61 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the CARD domain found in the DDX58 protein (also known as RIG1), which is a key protein in the cellular chordates' sentinel system to detect viral infection. This domain is near the N terminus of RIG1 and interacts with its C-terminal domain []. |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2016 |
Journal: |
EMBO Rep |
Title: |
RNF123 has an E3 ligase-independent function in RIG-I-like receptor-mediated antiviral signaling. |
Volume: |
17 |
Issue: |
8 |
Pages: |
1155-68 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of RING finger-containing proteins, including RNF123/RSPRY1 from humans and RKP from Arabidopsis.RNF123 is the catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. It also functions as an inhibitor of innate antiviral signalling mediated by DDX58 and IFIH1 independently of its E3 ligase activity []. The role of RSPRY1 (RING finger and SPRY domain-containing protein 1) is not known, but it may have a role in bone development. Mutations in RSPRY1 cause skeletal dysplasia [].RKP is an E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of KRP1 and KRP2 [, ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Sheikh F |
Year: |
2014 |
Journal: |
J Leukoc Biol |
Title: |
An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages. |
Volume: |
96 |
Issue: |
4 |
Pages: |
591-600 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li ZA |
Year: |
2024 |
Journal: |
Virus Res |
Title: |
Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response. |
Volume: |
342 |
|
Pages: |
199335 |
|
•
•
•
•
•
|
Publication |
First Author: |
Faden M |
Year: |
2015 |
Journal: |
Am J Hum Genet |
Title: |
Identification of a Recognizable Progressive Skeletal Dysplasia Caused by RSPRY1 Mutations. |
Volume: |
97 |
Issue: |
4 |
Pages: |
608-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lai J |
Year: |
2009 |
Journal: |
Plant J |
Title: |
RKP, a RING finger E3 ligase induced by BSCTV C4 protein, affects geminivirus infection by regulation of the plant cell cycle. |
Volume: |
57 |
Issue: |
5 |
Pages: |
905-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren H |
Year: |
2008 |
Journal: |
Plant J |
Title: |
Degradation of the cyclin-dependent kinase inhibitor KRP1 is regulated by two different ubiquitin E3 ligases. |
Volume: |
53 |
Issue: |
5 |
Pages: |
705-16 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
267
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
267
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
503
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1239
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
549
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1025
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1314
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
576
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
733
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1025
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
707
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1025
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
924
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
925
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|